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Journals Diseases of the Esophagus : Of...

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus

https://read.qxmd.com/read/38862393/impact-of-bulky-loco-regional-lymphadenopathy-in-esophageal-adenocarcinoma-on-survival-a-retrospective-single-center-analysis
#1
JOURNAL ARTICLE
James Tankel, Yehonathan Nevo, Ruqaiya Al Shehhi, Rawan Sakalla, Mehrnoush Dehghani, Jonathan Spicer, Sara Najmeh, Carmen Mueller, Lorenzo Ferri, Jonathan Cools-Lartigue
The relationship between 'bulky' locoregional lymphadenopathy and survival has not been investigated in the setting of esophageal adenocarcinoma (EAC). This study aimed to explore whether bulky regional lymphadenopathy at diagnosis affected survival outcomes in patients with EAC treated with neoadjuvant chemotherapy and en bloc resection. A single-center retrospective review of a prospectively maintained upper GI cancer surgical database was performed between January 2012 and December 2019. Patients with locally advanced EAC (cT2-3, N+, M0) treated with neoadjuvant docetaxel-based chemotherapy and transthoracic en bloc esophagogastrectomy were identified...
June 12, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38857460/diagnostic-differences-in-high-resolution-esophageal-motility-in-a-large-mexican-cohort-based-on-geographic-distribution
#2
JOURNAL ARTICLE
Genaro Vázquez-Elizondo, José María Remes-Troche, Miguel Ángel Valdovinos-Díaz, Enrique Coss-Adame, Edgardo Suárez Morán, Sami R Achem
High-resolution esophageal manometry [HRM] has become the gold standard for the evaluation of esophageal motility disorders. It is unclear whether there are HRM differences in diagnostic outcome based on regional or geographic distribution. The diagnostic outcome of HRM in a diverse geographical population of Mexico was compared and determined if there is variability in diagnostic results among referral centers. Consecutive patients referred for HRM during 2016-2020 were included. Four major referral centers in Mexico participated in the study: northeastern, southeastern, and central (Mexico City, two centers)...
June 11, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38847416/impact-of-pre-existing-mesh-at-the-hiatus-at-revisional-hiatal-hernia-surgery
#3
JOURNAL ARTICLE
Ahmed W H Barazanchi, Juanita Noeline Chui, Nazim Bhimani, Steven Leibman, Garett Smith
Recurrence after laparoscopic hiatus hernia repair (LHR) is high, with few symptomatic patients undergoing redo LHR. Morbidity is higher in redo surgery compared with the primary operation. Tens of studies have explored the safety of redoing LHR. However, the impact of existing mesh on operative risk is rarely examined. We aim to assess the impact of mesh at the hiatus on the safety of redo LHR. This was a cohort study examining redo LHR patients from a prospectively maintained database from January 2002 to December 2023...
June 7, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38836354/overall-survival-after-definitive-chemoradiotherapy-for-patients-with-esophageal-cancer-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
Charlène J van der Zijden, Anna Bouwman, Bianca Mostert, Joost J M E Nuyttens, Pieter C van der Sluis, Manon C W Spaander, Jan Willem M Mens, Marjolein Y V Homs, Leni van Doorn, Bas P L Wijnhoven, Sjoerd M Lagarde
Definitive chemoradiotherapy (dCRT) is a potentially curative therapy for esophageal cancer. As indications for dCRT differ widely, it is challenging to draw conclusions on outcomes and survival. The aim of this study was to evaluate overall survival (OS) and recurrence patterns according to indications for treatment. Patients who underwent dCRT (50.4 Gy concomitant with carboplatin/paclitaxel) for esophageal cancer between 2012 and 2022 were identified. Indications for dCRT were: cervical tumor, irresectable disease, unfit for surgery, and patient and/or physician preference...
June 5, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38769843/the-effect-of-a-pre-and-post-operative-exercise-program-versus-standard-care-on-physical-activity-and-sedentary-behavior-of-patients-with-esophageal-and-gastric-cancer-undergoing-neoadjuvant-treatment-prior-to-surgery-the-periop-og-trial-a-randomized-controlled
#5
JOURNAL ARTICLE
Lisa Loughney, Kate Murphy, Roisin Tully, William B Robb, Noel McCaffrey, Kieran Dowd, Fiona Skelly
Neoadjuvant cancer treatment (NCT) reduces both physical fitness and physical activity (PA) levels, which can increase the risk of adverse outcomes in cancer patients. This study aims to determine the effect of exercise prehabilitation on PA and sedentary behavior (SB) in patients undergoing NCT and surgery for esophagogastric malignancies. This study is a randomized pragmatic controlled multi-center trial conducted across three Irish hospitals. Participants were aged ≥18 years scheduled for esophagectomy or gastrectomy and were planned for NCT and surgery...
May 20, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38762331/gastric-conduit-reconstruction-after-esophagectomy
#6
JOURNAL ARTICLE
Masayuki Watanabe, Naoki Takahashi, Masahiro Tamura, Masayoshi Terayama, Kengo Kuriyama, Akihiko Okamura, Jun Kanamori, Yu Imamura
A high risk of complications still accompanies gastric conduit reconstruction after esophagectomy. In this narrative review, we summarize the technological progress and the problems of gastric conduit reconstruction after esophagectomy. Several types of gastric conduits exist, including the whole stomach and the narrow gastric tube. The clinical outcomes are similar between the two types of conduits. Sufficient blood supply to the conduit is mandatory for a successful esophageal reconstruction. Recently, due to the availability of equipment and its convenience, indocyanine green angiography has been rapidly spreading...
May 18, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38745437/risk-factors-and-prognosis-for-supraclavicular-lymph-node-metastasis-in-patients-with-thoracic-esophageal-cancer-distant-or-regional-metastasis
#7
JOURNAL ARTICLE
Osamu Shiraishi, Takaomi Hagi, Yoko Hiraki, Hiroaki Kato, Masashi Koda, Tomoya Nakanishi, Atsushi Yasuda, Masayuki Shinkai, Motohiro Imano, Takushi Yasuda
We aimed to determine the frequency and prognosis of supraclavicular (#104) lymph node (LN) metastasis compared with other LN stations in patients with advanced thoracic esophageal cancer and to identify risk factors for metastasis to delineate the indications for three-field lymphadenectomy (3FL). The study cohort of 567 eligible patients with esophageal cancer had undergone subtotal esophagectomy from 2003 to 2020. LN metastasis was defined as pathologically proven metastasis or positron emission tomography-positive LNs...
May 14, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38745432/exploring-x-barriers-to-care-for-eosinophilic-esophagitis
#8
JOURNAL ARTICLE
Shivani U Thanawala, Ari Klein, Krish Raval, Jesus Ivan Flores Amaro, Claire A Beveridge, Amanda B Muir, Gary W Falk, Graciela Gonzalez-Hernandez, Kristle L Lynch
Patients with chronic diseases have increasingly turned to social media to discuss symptoms and share the challenges they face with disease management. The primary aim of this study is to use naturally occurring data from X (formerly known as Twitter) to identify barriers to care faced by individuals affected by eosinophilic esophagitis (EoE). For this qualitative study, the X application programming interface with academic research access was used to search for posts that referenced EoE between 1 January 2019 and 10 August 2022...
May 14, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38745429/treatment-of-anastomotic-leakage-following-ivor-lewis-esophagectomy-10%C3%A2-year-experience-from-a-nordic-center
#9
JOURNAL ARTICLE
Tobias Hauge, Thomas Dretvik, Egil Johnson, Tom Mala
Anastomotic leakage (AL) is a dreaded complication following esophageal resection. No clear consensus exist for the optimal handling of this severe complication. The aim of this study was to describe the treatment outcome following AL. We conducted a retrospective cross-sectional study including all patients with AL operated with Ivor Lewis esophagectomy from 2010 to 2021 at Oslo University Hospital, Norway. 74/526 (14%) patients had AL. Patient outcomes were analyzed and categorized according to main AL treatment strategy; stent (54%), endoscopic vacuum therapy and stent (EVT + stent) (19%), nasogastric tube and antibiotics (conservative) (16%), EVT (8%) and by other endoscopic means (other) (3%)...
May 14, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38741462/current-state-of-rumination-syndrome
#10
JOURNAL ARTICLE
Sydney Pomenti, David A Katzka
Rumination syndrome (RS) is an underdiagnosed behavioral disorder of recurrent regurgitation. Regurgitation occurs in RS due to increased gastric pressure achieved by subconscious contraction of the abdominal musculature wall, reversing the pressure gradient between the esophagus and the stomach. RS is mainly diagnosed clinically by the Rome Criteria with symptoms of regurgitation without retching of recently ingested food into the mouth and subsequent spitting or re-mastication. When the diagnosis is unable to be made clinically, supportive testing including fed impedance manometry can be considered...
May 13, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38693752/prognostic-impact-of-nodal-status-and-lymphovascular-invasion-in-patients-undergoing-neoadjuvant-chemotherapy-for-esophageal-squamous-cell-carcinoma
#11
JOURNAL ARTICLE
Hiroshi Miyata, Keijirou Sugimura, Takashi Kanemura, Tomohira Takeoka, Takahito Sugase, Masayoshi Yasui, Junichi Nishimura, Hiroshi Wada, Hiroshi Akita, Masaaki Yamamoto, Hisashi Hara, Naoki Shinno, Takeshi Omori, Masahiko Yano
Nodal status is well known to be the most important prognostic factor for esophageal cancer patients, even if they are treated with neoadjuvant therapy. To establish an optimal postoperative adjuvant strategy for patients, we aimed to more accurately predict the prognosis of patients and systemic recurrence by using clinicopathological factors, including nodal status, in patients with esophageal cancer who received neoadjuvant chemotherapy. The clinicopathological factors associated with survival and systemic recurrence were investigated in 488 patients with esophageal squamous cell carcinoma who received neoadjuvant chemotherapy...
May 1, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38688726/impaired-esophagogastric-junction-relaxation-and-lung-transplantation-outcomes
#12
JOURNAL ARTICLE
Andrés R Latorre-Rodríguez, Madison Golla, Ashwini Arjuna, Ross M Bremner, Sumeet K Mittal
The implications of impaired esophagogastric junction relaxation (i.e. esophagogastric junction outflow obstruction and achalasia) in lung transplants recipients (LTRs) are unclear. Thus, we examined the prevalence and clinical outcomes of LTRs with an abnormally elevated integrated relaxation pressure (IRP) on high-resolution manometry before lung transplantation (LTx). After IRB approval, we reviewed data on LTRs who underwent LTx between January 2019 and August 2022 with a preoperative median IRP >15 mmHg...
April 30, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38679488/expression-of-inducible-nitric-oxide-synthase-nitrotyrosine-eosinophilic-peroxidase-eotaxin-3-and-galectin-3-in-patients-with-gastroesophageal-reflux-disease-eosinophilic-esophagitis-and-in-healthy-controls-a-semiquantitative-image-analysis-of-3-3-diaminobenzidine
#13
JOURNAL ARTICLE
John Plate, Mogens Bove, Helen M Larsson, Elisabeth Norder Grusell, Nabanita Chatterjee, Leif E Johansson, Henrik Bergquist
Eosinophilic esophagitis (EoE) and gastroesophageal reflux disease (GERD) share many histopathological features; therefore, markers for differentiation are of diagnostic interest and may add to the understanding of the underlying mechanisms. The nitrergic system is upregulated in GERD and probably also in EoE. Esophageal biopsies of patients with EoE (n = 20), GERD (n = 20), and healthy volunteers (HVs) (n = 15) were exposed to antibodies against inducible nitric oxide synthase (iNOS), nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3...
April 28, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38678385/contemporary-outcomes-of-left-thoraco-abdominal-esophagectomy-due-to-cancer-in-the-esophagus-or-gastroesophageal-junction-a-multicenter-cohort-study
#14
JOURNAL ARTICLE
F Klevebro, S Ash, C Mueller, G M Garbarino, S S Gisbertz, M I van Berge Henegouwen, Y Mandeville, L Ferri, A Davies, N Maynard, D E Low
Surgery for cancer of the esophagus or gastro-esophageal junction can be performed with a variety of minimally invasive and open approaches. The left thoracoabdominal esophagectomy (LTE) is an open technique that gives an opportunity to operate in the chest and abdomen with excellent exposure of the gastro-esophageal junction through a single incision, and there is currently no equivalent minimally invasive technique available. The aim of this multi-institutional review was to study a large contemporary international study cohort of patients treated with LTE...
April 28, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38670809/mucosal-impedance-as-a-diagnostic-tool-for-gastroesophageal-reflux-disease-an-update-for-clinicians
#15
JOURNAL ARTICLE
Matthew Marshall-Webb, Jennifer C Myers, David I Watson, Tim Bright, Taher I Omari, Sarah K Thompson
Mucosal impedance is a marker of esophageal mucosal integrity and a novel technique for assessing esophageal function and pathology. This article highlights its development and clinical application for gastroesophageal reflux disease (GERD), Barrett's esophagus, and eosinophilic esophagitis. A narrative review of key publications describing the development and use of mucosal impedance in clinical practice was conducted. A low mean nocturnal baseline impedance (MNBI) has been shown to be an independent predictor of response to anti-reflux therapy...
April 26, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38670808/centralization-and-quality-control-in-esophageal-cancer-surgery-a-way-forward-in-europe
#16
JOURNAL ARTICLE
Maurits R Visser, Mark I van Berge Henegouwen, Richard van Hillegersberg
No abstract text is available yet for this article.
April 26, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38670807/western-european-variation-in-the-organization-of-esophageal-cancer-surgical-care
#17
JOURNAL ARTICLE
Maurits R Visser, Daan M Voeten, Suzanne S Gisbertz, Jelle P Ruurda, Michael P Achiam, Magnus Nilsson, Sheraz R Markar, Manuel Pera, Riccardo Rosati, Guillaume Piessen, Philippe Nafteux, Christian A Gutschow, Peter P Grimminger, Jari V Räsänen, John V Reynolds, Hans-Olaf Johannessen, Pedro Vieira, Michael Weitzendorfer, Aristotelis Kechagias, Mark I van Berge Henegouwen, Richard van Hillegersberg
Reasons for structural and outcome differences in esophageal cancer surgery in Western Europe remain unclear. This questionnaire study aimed to identify differences in the organization of esophageal cancer surgical care in Western Europe. A cross-sectional international questionnaire study was conducted among upper gastrointestinal (GI) surgeons from Western Europe. One surgeon per country was selected based on scientific output and active membership in the European Society for Diseases of the Esophagus or (inter)national upper GI committee...
April 26, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38661378/association-of-perioperative-oral-swallowing-function-with-post-esophagectomy-outcomes-and-nutritional-statuses-in-patients-with-esophageal-cancer
#18
JOURNAL ARTICLE
Sohei Matsumoto, Kohei Wakatsuki, Hiroshi Nakade, Tomohiro Kunishige, Shintaro Miyao, Satoko Aoki, Akinori Tsujimoto, Takanari Tatsumi, Masahiro Soga, Masayuki Sho
Dysphagia after esophagectomy is a serious complication; however, no method has been established to accurately assess swallowing function. We evaluated the association of swallowing function tests with patients' post-esophagectomy complications and nutritional statuses. We retrospectively reviewed the data of 95 patients with esophageal cancer who underwent esophagectomy between 2016 and 2021. We performed perioperative swallowing function tests, including the repetitive saliva swallowing test (RSST), maximum phonation time (MPT), and laryngeal elevation (LE)...
April 25, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38659256/safety-and-efficacy-of-esoflip-dilation-in-patients-with-esophageal-dysmotility-a-systematic-review
#19
JOURNAL ARTICLE
Umair Iqbal, Michael Yodice, Zohaib Ahmed, Hafsa Anwar, Syeda Faiza Arif, Wade M Lee-Smith, David L Diehl
Esophageal manometry is utilized for the evaluation and classification of esophageal motility disorders. EndoFlip has been introduced as an adjunctive test to evaluate esophagogastric junction (EGJ) distensibility. Treatment options for achalasia and EGJ outflow obstruction (EGJOO) include pneumatic dilation, myotomy, and botulinum toxin. Recently, a therapeutic 30 mm hydrostatic balloon dilator (EsoFLIP, Medtronic, Minneapolis, MN, USA) has been introduced, which uses impedance planimetry technology like EndoFlip...
April 24, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/38587429/metabolic-dysfunction-associated-steatotic-liver-disease-and-risk-of-esophageal-cancer-in-patients-with-diabetes-mellitus-a-nationwide-cohort-study
#20
JOURNAL ARTICLE
Yeong Jeong Jeon, Kyungdo Han, Seung Woo Lee, Ji Eun Lee, Junhee Park, In Young Cho, Jong Ho Cho, Dong Wook Shin
Metabolic dysfunction-associated steatotic liver disease (MASLD) is closely associated with type 2 diabetes and a developing several cancers including esophageal cancer (EC). However, the association between MASLD and EC in diabetic patients has not been investigated. Therefore, we aimed to investigate the relation between MASLD and developing EC in diabetic patients. This was a population-based retrospective cohort study of data from the Korean National Health Insurance Service (NHIS). A total of 1,904,468 subjects diagnosed with diabetes who underwent NHIS-provided health checkups from 2009 to 2012 were included...
April 8, 2024: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
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