journal
https://read.qxmd.com/read/38688657/retraction
#1
JOURNAL ARTICLE
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No abstract text is available yet for this article.
2024: In Vivo
https://read.qxmd.com/read/38688656/the-effect-of-roflumilast-on-lipopolysaccharide-induced-acute-lung-injury-during-neutropenia-recovery-in-mice
#2
JOURNAL ARTICLE
Kyu Yean Kim, Young Ae Kim, Hyon Soo Joo, Jin Woo Kim
BACKGROUND/AIM: Patients with pneumonia after prolonged neutropenia are at increased risk for acute respiratory distress syndrome (ARDS). The key molecule of endothelial barrier breakdown in sepsis is lipopolysaccharide (LPS), which is a component of the outer membrane of gram-negative bacterial cell walls. Maintaining increased cyclic adenosine monophosphate (cAMP) levels in endothelial cells is effective in preventing endothelial dysfunction and microvascular permeability. The aim of this study was to elucidate whether roflumilast, a phosphodiesterase-4 (PDE-4) inhibitor, is effective in LPS-induced acute lung injury (ALI) during neutropenia recovery in a murine model...
2024: In Vivo
https://read.qxmd.com/read/38688655/patient-reported-outcome-measure-prom-rand-36-item-health-survey-for-gallstone-disease-patients-five-years-following-surgery-a-prospective-randomized-study
#3
RANDOMIZED CONTROLLED TRIAL
Anni Repo, Maaret Eskelinen, Iina Saimanen, Tuomas Selander, Jari Kärkkäinen, Petri Juvonen, Samuli Aspinen, Jukka Pulkkinen, Matti Eskelinen
BACKGROUND/AIM: There are no studies assessing the long-term quality of life (QoL) following three-dimensional laparoscopy cholecystectomy (3D-LC) in patients with cholelithiasis (Chole). PATIENTS AND METHODS: A cohort of 200 patients with Chole were randomized into 3D-LC or minilaparotomy cholecystectomy (MC) groups. RAND-36 survey was performed before randomization, four weeks and five years postoperatively. RESULTS: Similar postoperative five years RAND-36 scores were reported in the 3D-LC and MC groups...
2024: In Vivo
https://read.qxmd.com/read/38688654/role-of-high-sensitivity-c-reactive-protein-in-future-cardiovascular-events-in-hemodialysis-patients
#4
JOURNAL ARTICLE
Hiroshi Osawa, Norio Nakamura, Chikako Tsutaya, Hisao Saitoh, Michiko Shimada, Reiichi Murakami, Takeshi Fujita, Ikuyo Narita-Kinjo, Daiki Nagawa, Masamichi Nakata, Takashi Yokota, Chikara Ohyama, Hirofumi Tomita
BACKGROUND/AIM: The pathogenesis of cardio-vascular disease (CVD) in hemodialysis (HD) patients involves inflammation and oxidative stress. High-sensitivity C-reactive protein (hs-CRP) is an established inflammatory biomarker associated with CVD. Several studies have suggested that the inflammatory biomarker pentraxin-3 (PTX-3) and the oxidative stress-related biomarker soluble lectin-like low-density lipoprotein receptor-1 (sLOX-1) are novel biomarkers for CVD in non-HD populations. This study aimed to clarify the association of these established and novel biomarkers with future cardiovascular (CV) events in HD patients...
2024: In Vivo
https://read.qxmd.com/read/38688653/artificial-intelligence-and-chatgpt-in-abdominopelvic-surgery-a-systematic-review-of-applications-and-impact
#5
REVIEW
Marta Goglia, Marco Pace, Marco Yusef, Gaetano Gallo, Matteo Pavone, Niccolò Petrucciani, Paolo Aurello
BACKGROUND/AIM: The integration of AI and natural language processing technologies, such as ChatGPT, into surgical practice has shown promising potential in enhancing various aspects of abdominopelvic surgical procedures. This systematic review aims to comprehensively evaluate the current state of research on the applications and impact of artificial intelligence (AI) and ChatGPT in abdominopelvic surgery summarizing existing literature towards providing a comprehensive overview of the diverse applications, effectiveness, challenges, and future directions of these innovative technologies...
2024: In Vivo
https://read.qxmd.com/read/38688652/the-role-of-radiotherapy-for-meningeal-melanocytomas-a-20-year-update
#6
JOURNAL ARTICLE
Dirk Rades, Oksana Zemskova, Jan Gliemroth, Nathan Y Yu
BACKGROUND/AIM: Meningeal melanocytomas are rare tumors of the central nervous system and optimal treatment needs further clarification. This study compared subtotal resection (STR), STR plus radiation therapy (RT), gross total resection (GTR), and GTR+RT to better define the role of postoperative RT. PATIENTS AND METHODS: All cases reported in the literature were reviewed. Patients (n=184) with complete data were analyzed for local control (LC) and overall survival (OS)...
2024: In Vivo
https://read.qxmd.com/read/38688651/long-term-intravital-investigation-of-an-orthotopic-glioma-mouse-model-via-optical-coherence-tomography-angiography
#7
JOURNAL ARTICLE
Kaili Zheng, Guangxing Wang, Kangwei Zhou, Xiaofei Wen, Yuying Zhou, Shuting Ling, Qiong Yang, Huiling Wu, Jiwei Xing, Lisong Lin, Qingliang Zhao
BACKGROUND/AIM: Probing brain tumor microvasculature holds significant importance in both basic cancer research and medical practice for tracking tumor development and assessing treatment outcomes. However, few imaging methods commonly used in clinics can noninvasively monitor the brain microvascular network at high precision and without exogenous contrast agents in vivo. The present study aimed to investigate the characteristics of microvasculature during brain tumor development in an orthotopic glioma mouse model...
2024: In Vivo
https://read.qxmd.com/read/38688650/risk-and-time-to-onset-of-acute-kidney-injury-with-vancomycin-plus-piperacillin-tazobactam-combination-analysis-using-jader
#8
JOURNAL ARTICLE
Naohito Ide, Ken-Ichi Sako, Masaki Takigawa, Hiroyuki Tanaka
BACKGROUND/AIM: Pharmacovigilance data and clinical studies have indicated a risk of acute kidney injury (AKI) associated with concomitant administration of vancomycin and piperacillin-tazobactam. However, no pharmacovigilance studies have evaluated time-to-onset and outcomes of AKI related to this combination. Therefore, this study used a pharmacovigilance database to investigate the incidence, time-to-onset, and outcomes of AKI in patients treated with intravenous vancomycin plus piperacillin-tazobactam or other antipseudomonal antibiotics...
2024: In Vivo
https://read.qxmd.com/read/38688649/correlation-between-low-cytoplasmic-expression-of-xbp1-and-the-likelihood-of-surviving-hepatocellular-carcinoma
#9
JOURNAL ARTICLE
Hui-Ting Hsu, Yueh-Min Lin, Ming-Tai Hsing, Kun-Tu Yeh, Jeng-Wei Lu, Shun-Fa Yang
BACKGROUND/AIM: Our objectives in this study were to (i) evaluate the clinical significance of X-box-binding protein 1 (XBP1) expression in cases of hepatocellular carcinoma (HCC) and (ii) assess the potential of XBP1 to be used as a prognostic biomarker. PATIENTS AND METHODS: The expression of XBP1 protein in 267 HCC tissue specimens was measured using immunohistochemistry in order to characterize the associations among XBP1 expression, clinicopathological factors and survival outcomes...
2024: In Vivo
https://read.qxmd.com/read/38688648/progression-to-lymph-node-metastasis-after-spontaneous-regression-of-pulmonary-adenocarcinoma-following-biopsy
#10
JOURNAL ARTICLE
Kyoichi Kaira, Hisao Imai, Atsuto Mouri, O U Yamaguchi, Hiroshi Kagamu
BACKGROUND/AIM: Spontaneous regression (SR) of cancer, which indicates the natural disappearance of malignant tumors, is rare. Little is known about the mechanisms underlying SR; however, immunological reactions, infections, injuries, and medications have been presumed. Among previously reported cases of SR, lung cancer cases have been extremely limited. CASE REPORT: Here, we present a case of lymph node metastasis exacerbation after SR of a primary adenocarcinoma following a biopsy...
2024: In Vivo
https://read.qxmd.com/read/38688647/oncological-outcomes-in-men-with-favorable-intermediate-risk-prostate-cancer-enrolled-in-active-surveillance
#11
JOURNAL ARTICLE
Pietro Pepe, Ludovica Pepe, Michele Pennisi, Filippo Fraggetta
BACKGROUND/AIM: To evaluate the long-term oncological outcomes in men with intermediate risk prostate cancer (PCa) enrolled in active surveillance (AS). PATIENTS AND METHODS: From April 2015 to December 2022, 30 men with Gleason score 3+4/ISUP Grade Group2 (GG2), greatest percentage of cancer (GPC) ≤50%, Gleason pattern 4 ≤10%, ≤3 positive biopsy cores were enrolled in AS. All patients underwent confirmatory transperineal saturation biopsy (SPBx: 20 cores) 12 months from diagnosis plus multiparametric magnetic resonance (mpMRI) evaluation...
2024: In Vivo
https://read.qxmd.com/read/38688646/dectin-1-syk-activation-induces-antimicrobial-peptide-and-negative-regulator-of-nf-%C3%AE%C2%BAb-signaling-in-human-oral-epithelial-cells
#12
JOURNAL ARTICLE
Megumi Inomata, Masayo Abe, Yasuko Kawase, Toru Hayashi, Shigeru Amano, Hiroshi Sakagami
BACKGROUND/AIM: Oral epithelial cells serve as the primary defense against microbial exposure in the oral cavity, including the fungus Candida albicans. Dectin-1 is crucial for recognition of β-glucan in fungi. However, expression and function of Dectin-1 in oral epithelial cells remain unclear. MATERIALS AND METHODS: We assessed Dectin-1 expression in Ca9-22 (gingiva), HSC-2 (mouth), HSC-3 (tongue), and HSC-4 (tongue) human oral epithelial cells using flow cytometry and real-time polymerase chain reaction...
2024: In Vivo
https://read.qxmd.com/read/38688645/methionine-dependence-of-hair-maintenance-in-c57bl-6-mice
#13
JOURNAL ARTICLE
Yutaro Kubota, Nundini Varshney, Keita Kobayashi, Takuya Tsunoda, Robert M Hoffman
BACKGROUND/AIM: Hair-follicle keratinocytes contain high levels of cysteine, which is derived from methionine, rapidly proliferate, and form the hair shaft. The high proliferation rate of hair-follicle keratinocytes resembles that of aggressive cancer cells. In the present study, we determined the effect of a methionine-deficient diet on hair loss (alopecia) in mice with or without homocysteine supplementation. MATERIALS AND METHODS: Mice were fed a normal rodent diet (2020X, ENVIGO) (Group 1); a methionine-choline-deficient diet (TD...
2024: In Vivo
https://read.qxmd.com/read/38688644/acute-myelomonoblastic-leukemia-my1-de-a-preclinical-rat-model
#14
JOURNAL ARTICLE
Viktória Arató, Zita Képes, Judit P Szabó, Gergely Farkasinszky, Tamás Sass, Noémi Dénes, Adrienn Kis, Gábor Opposits, István Jószai, Ferenc Krisztián Kálmán, István Hajdu, György Trencsényi, István Kertész
BACKGROUND/AIM: Since acute myeloid leukemias still represent the most aggressive type of adult acute leukemias, the profound understanding of disease pathology is of paramount importance for diagnostic and therapeutic purposes. Hence, this study aimed to explore the real-time disease fate with the establishment of an experimental myelomonoblastic leukemia (My1/De) rat model using preclinical positron emission tomography (PET) and whole-body autoradiography. MATERIALS AND METHODS: In vitro [18 F]F-FDG uptake studies were performed to compare the tracer accumulation in the newly cultured My1/De tumor cell line (blasts) with that in healthy control and My1/De bone marrow suspensions...
2024: In Vivo
https://read.qxmd.com/read/38688643/feasibility-and-satisfaction-with-the-word-catheter-in-treatment-of-bartholin-s-cyst-and-abscess
#15
JOURNAL ARTICLE
Iason Psilopatis, Julius Emons, Georgia Levidou, Thomas Hildebrandt, Jutta Pretscher, Sven Kehl
BACKGROUND/AIM: The Word catheter is a silicone device with a balloon system that may be inserted into a Bartholin's cyst or abscess in order to provide drainage and epithelization. The aim of this study was to evaluate the Word catheter as a therapy for Bartholin's cyst and abscess. Both patient and physician satisfaction, as well as the feasibility in an outpatient setting, were examined. PATIENTS AND METHODS: A total of 51 women with a Bartholin's cyst or abscess were given the option of Word catheter insertion in an outpatient setting between August 2013 and March 2018...
2024: In Vivo
https://read.qxmd.com/read/38688642/primary-omental-torsion-in-children-in-the-laparoscopy-era-what-have-we-learned-so-far
#16
JOURNAL ARTICLE
Vasileios Alexopoulos, Xenophon Sinopidis, Aspasia Louta, Christos Damaskos, Nikolaos Garmpis, Gerasimos Tsourouflis, Stylianos Kykalos, Katerina Kambouri, Evangelos Blevrakis, Stylianos Roupakias, Antonios Panagidis, Dimitrios Dimitroulis
BACKGROUND/AIM: Primary omental torsion is uncommon, mimicking appendicitis and other acute abdominal pathologies. It often escapes diagnosis on imaging investigation or conventional open laparotomy. This study aimed to evaluate the effect of laparoscopy on the various parameters of this entity, including incidence, diagnosis, and treatment. MATERIALS AND METHODS: A systematic review was performed, including PubMed and Scopus databases, without a time limit, following the PRISMA principles...
2024: In Vivo
https://read.qxmd.com/read/38688641/parotid-gland-cancer-with-first-bite-syndrome-detected-via-ct-guided-fine-needle-aspiration-cytology
#17
JOURNAL ARTICLE
Misato Haneda, Isaku Okamoto, Akira Shimizu, Sayaka Arai, Tatsuya Yamakura, Daisuke Yunaiyama, Kiyoaki Tsukahara
BACKGROUND/AIM: First bite syndrome (FBS) is a symptom of severe pain at the beginning of a meal that lessens as the meal progresses. It is a common postoperative complication of parapharyngeal space tumors and is rarely reported as the first symptom of parotid carcinoma. The parapharyngeal space is considered a difficult area for approach; hence, preoperative histopathology is often challenging. However, there are hardly any reports on the approach of performing biopsies under computerized tomography (CT) guidance...
2024: In Vivo
https://read.qxmd.com/read/38688640/augmentation-of-therapeutic-efficacy-of-extraction-of-causative-teeth-by-irrigation-for-odontogenic-maxillary-sinusitis
#18
JOURNAL ARTICLE
Takao Kato, Hiroshi Sakagami
BACKGROUND/AIM: Odontogenic maxillary sinusitis is a clinically popular disease, but radical surgery and endoscopic surgery are often required. In the present study, we compared for the first time the therapeutic efficacy of the extraction of causative teeth with or without irrigation of the extraction fossa. PATIENTS AND METHODS: A total of 60 patients underwent extraction of causative tooth. Among them, 34 patients underwent irrigation, while other 26 patients did not...
2024: In Vivo
https://read.qxmd.com/read/38688639/robust-rat-and-mouse-models-of-bilateral-renal-ischemia-reperfusion-injury
#19
JOURNAL ARTICLE
Tanya Smith, Aeliya Zaidi, Charlotte Victoria Maynard Brown, Gilda Pino-Chavez, Timothy Bowen, Soma Meran, Donald Fraser, Rafael Chavez, Usman Khalid
BACKGROUND/AIM: Acute and chronic kidney diseases are a major contributor to morbidity and mortality worldwide, with no specific treatments currently available for these. To enable understanding the pathophysiology of and testing novel treatments for acute and chronic kidney disease, a suitable in vivo model of kidney disease is essential. In this article, we describe two reliable rodent models (rats and mice) of efficacious kidney injury displaying acute to chronic kidney injury progression, which is also reversible through novel therapeutic strategies such as ischemic preconditioning (IPC)...
2024: In Vivo
https://read.qxmd.com/read/38688638/evaluation-of-biocompatibility-and-healing-properties-of-dural-substitutes-produced-by-electrospinning-technology
#20
JOURNAL ARTICLE
Minjoo Cho, Kyung Mi Shim, Sang Soo Park, Seong Soo Kang, Kwangsik Jang, Se Eun Kim
BACKGROUND/AIM: Dural reconstruction is a critical process after neurosurgical procedures. Improper dural repair leads to serious side-effects, such as cerebrospinal fluid leakage or infection. This is why it is important to properly repair the dura using a dural substitute, and research into dural substitutes is ongoing. The ideal dural substitute should be non-toxic, biocompatible, and capable of maintaining adequate tension and preventing cerebrospinal fluid leakage for extended periods in vivo...
2024: In Vivo
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