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Journal of Cardiology

Naofumi Amioka, Toru Miyoshi, Hiroaki Otsuka, Daisuke Yamada, Atsushi Takaishi, Masayuki Ueeda, Satoshi Hirohata, Hiroshi Ito
BACKGROUND: Malondialdehyde-modified low-density lipoprotein (MDA-LDL) is a predictive marker of cardiovascular events in patients with stable angina pectoris. However, little is known about this marker in patients with acute coronary syndrome (ACS). We investigated the prognostic relevance of MDA-LDL to cardiovascular outcomes in patients with ACS. METHODS: A total of 370 consecutive patients with ACS who underwent primary percutaneous coronary intervention (PCI) were enrolled from October 2009 to September 2014 at Mitoyo General Hospital...
March 18, 2019: Journal of Cardiology
Tetsuo Yamaguchi, Toshihiro Nozato, Naoyuki Miwa, Yuichiro Sagawa, Keita Watanabe, Yasutoshi Nagata, Ryoichi Miyazaki, Kentaro Mitsui, Masashi Nagase, Tatsuhiro Nagamine, Junji Yamaguchi, Ryo Masuda, Masakazu Kaneko, Nobuhiro Hara, Takashi Ashikaga
BACKGROUND: Malnutrition is associated with a poor prognosis in heart failure, angina pectoris, and peripheral artery disease. However, the clinical importance of the preprocedural nutrition status of patients requiring pacemaker implantation (PMI) for bradycardia is unclear. METHODS: We retrospectively enrolled 521 patients (median 79 years) who underwent their first PMI between January 1, 2012 and June 30, 2017. The nutrition status before implantation was assessed by the geriatric nutritional risk index (GNRI)...
March 14, 2019: Journal of Cardiology
Guiling Ma, Yidan Wang, Dongyan Hou, Jiamei Liu, Juan Zhang, Lin Xu, Hua Wang, Wenshu Zhao, Yuan Zhang, Lin Zhang
BACKGROUND: Peripartum cardiomyopathy (PPCM) is characterized by heart failure. Our previous study found that autoantibodies against the M2-muscarinic receptor (anti-M2-R) are increased in PPCM patients. We aimed to evaluate the association of anti-M2-R on prognosis of PPCM patients with standard treatment. METHODS: Synthetic peptides corresponding to the M2 receptor served as the target antigens in an enzyme-linked immunosorbent assay experiment. They were used to screen the sera of 80 PPCM patients, who were separated into anti-M2-R-negative and positive groups according to their anti-M2-R reactivity...
March 13, 2019: Journal of Cardiology
Evgeny Lyan, Kivanc Yalin, Amr Abdin, Noureddin Sawan, Spyridon Liosis, Stefan A Lange, Ingo Eitel, Christian-H Heeger, Roza Meyer-Saraei, Charlotte Eitel, Roland Richard Tilz
BACKGROUND: Data regarding atrial tachycardia (AT) following second-generation cryoballoon ablation (CBA) of atrial fibrillation (AF) are limited. AIM: To describe the incidence, mechanisms, and clinical predictors of ATs following CBA. METHODS AND RESULTS: In this retrospective single-center study 238 patients undergoing CBA for treatment of paroxysmal (91/238; 38.2%) or persistent AF were analyzed. During a mean follow-up of 11.9 ± 5...
March 13, 2019: Journal of Cardiology
Su Nam Lee, Donggyu Moon, Keon-Woong Moon, Ki-Dong Yoo
BACKGROUND: Many studies have reported both systemic inflammatory response and malnutrition provide valuable predictions of prognosis in patients with acute coronary syndrome (ACS). This study aims to assess the association between the Glasgow prognostic score (GPS) by combining C-reactive protein and serum albumin concentration, and clinical outcomes in patients with ACS. METHODS: This retrospective study included patients admitted for ACS between June 2010 and May 2013 in St...
March 13, 2019: Journal of Cardiology
Etsuko Tsuda, Osamu Yamada, Masataka Kitano
BACKGROUND: The treatment of heart failure has changed with the use of angiotensin-converting enzyme inhibitors (ACEIs) and beta-blockers since the middle of the 1990s. However, the outcome in infantile dilated cardiomyopathy (DCM) when treated with them remains poorly understood. METHODS: We reviewed the medical records of infants with DCM within 24 months old in our hospital between 1979 and 2012, and compared the outcome in the later group (1997-2012) with that in the early group (1979-1996)...
March 12, 2019: Journal of Cardiology
Hiroshi Inoue, Shinichiro Uchiyama, Hirotsugu Atarashi, Ken Okumura, Yukihiro Koretsune, Masahiro Yasaka, Takeshi Yamashita, Atsushi Taniguchi, Taku Fukaya
BACKGROUND: The effectiveness and safety of dabigatran etexilate (DE) have not been elucidated thoroughly in clinical practice for Japanese patients with non-valvular atrial fibrillation (NVAF). In particular, those of DE at a reduced dose due to dose reduction recommendations (DRR) remain unknown. METHODS: NVAF patients who had newly initiated DE treatment for prevention of thromboembolic events between December 2011 and November 2013 were enrolled. They were followed until August 2016...
March 11, 2019: Journal of Cardiology
Tomoharu Dohi, Daisaku Nakatani, Koichi Inoue, Shungo Hikoso, Takafumi Oka, Kenichi Hayashi, Masaharu Masuda, Yoshio Furukawa, Masato Kawasaki, Yasuyuki Egami, Kazunori Kashiwase, Akio Hirata, Tetsuya Watanabe, Miwa Miyoshi, Toshihiro Takeda, Akito Nakagawa, Hiroya Mizuno, Hitoshi Minamiguchi, Tetsuhisa Kitamura, Shinichiro Suna, Takayuki Kojima, Hirota Kida, Oeun Bolrathanak, Yuji Okuyama, Yasushi Sakata
BACKGROUND: Although extensive substrate modification in addition to pulmonary vein isolation (PVI) has been recommended in catheter ablation for persistent atrial fibrillation (AF), recent randomized controlled trials have not demonstrated efficacy of such additional ablations. METHODS AND STUDY DESIGN: The Osaka Cardiovascular Conference will conduct a multicenter, randomized, open-label trial aiming to examine whether PVI alone is non-inferior to PVI plus additional ablation such as linear ablation and/or complex fractionated atrial electrogram ablation in patients with persistent AF...
March 7, 2019: Journal of Cardiology
Jung Ok Kim, Jaemin Shim, Seung-Hyun Lee, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Il Choi, Jae Young Choi, Moon-Hyung Lee, Young-Hoon Kim, Byung-Chul Chang, Hui-Nam Pak
BACKGROUND: Although the hemodynamic burden and structural substrate contribute to valvular atrial fibrillation (VAF) mechanisms, the role of catheter ablation has rarely been reported. We investigated the clinical characteristics, mapping findings, and long-term rhythm outcomes after catheter ablation of hemodynamically corrected VAF. METHODS: We compared 77 patients with VAF (46.8% male, 52.7±8.8 years old, 46.8% paroxysmal AF, 24.7% with maze procedures) and 2244 patients with non-VAF (NVAF) who underwent catheter ablation...
March 5, 2019: Journal of Cardiology
Do Young Kim, Jong-Chan Youn, Myung-Soo Park, Sunki Lee, Suk-Won Choi, Kyu-Hyung Ryu, Lee Su Kim, Man-Shik Shim, Jae Jin Lee, Seongwoo Han
BACKGROUND: Cancer treatment increases the risk of cardiovascular (CV) events. However, the long-term CV outcome of breast cancer patients who undergo radiotherapy and chemotherapy concomitantly is unknown. This study aimed to determine the incidence and risk factors of CV events among these patients. METHODS: Six hundred sixty consecutive breast cancer patients older than 50 years from November 2005 to September 2015, were enrolled in four university hospitals...
February 28, 2019: Journal of Cardiology
Masahiko Goya
No abstract text is available yet for this article.
February 28, 2019: Journal of Cardiology
Chizuko A Kamiya, Jun Yoshimatsu
Maternal circulatory dynamics change drastically during pregnancy and delivery. Therefore, pregnancy with concomitant cardiovascular disease has risks, even for maternal death, in severe cases. This condition has tended to increase with advances in medical care and an increase in the age of pregnant women. Drug therapy during pregnancy and lactation should be administered if it is judged that this is necessary to improve the maternal pathology despite a risk of adverse effects. Fetuses and infants are exposed to maternal drugs, which is a specific concern in drug therapy for pregnant and lactating women...
February 26, 2019: Journal of Cardiology
Keiko Kajio, Kazuki Mizutani, Masahiko Hara, Mana Nakao, Tsukasa Okai, Asahiro Ito, Yosuke Takahashi, Shinichi Iwata, Taro Shimono, Yasuhiro Izumiya, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama
BACKGROUND: Little evidence is available regarding the risk of peri-procedural stroke detected by diffusion-weighted magnetic resonance imaging (DW-MRI) after transcatheter aortic valve replacement (TAVR). Our purpose was to evaluate stroke risk after TAVR using DW-MRI by enrolling consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI. METHODS: We prospectively enrolled 113 consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI...
February 19, 2019: Journal of Cardiology
Koji Yanaka, Hirokuni Akahori, Takahiro Imanaka, Kojiro Miki, Nagataka Yoshihara, Takamasa Tanaka, Masanori Asakura, Tohru Masuyama, Masaharu Ishihara
BACKGROUND: Peripheral artery disease (PAD) is often accompanied by heart failure with preserved ejection fraction (HFpEF). Left ventricular (LV) diastolic dysfunction is related to HFpEF. The aim of this study was to compare LV diastolic function between patients with or without PAD. METHODS: One thousand one hundred twenty-one patients (male 56%, mean age 68±13 years) with available preserved LV systolic function assessed by echocardiography (ejection fraction ≥50%) were enrolled from a single-center database between January 2013 and May 2015...
February 18, 2019: Journal of Cardiology
Ryusuke Miki, Masato Takeuchi, Takumi Imai, Tomotsugu Seki, Shiro Tanaka, Masaki Nakamura, Koji Kawakami
BACKGROUND: An admission to the intensive care unit (ICU) after developing acute myocardial infarction (AMI) has been the standard of care and is recommended by professional societies. However, evidence that justifies its use, such as a reduction in mortality, has never been shown despite the associated financial burden. This study aimed to investigate the association between ICU admission and a reduction in 30-day mortality in patients who developed AMI. METHODS: The multicenter retrospective cohort study was conducted using data from an administrative database between 2014 and 2016 in Japan...
February 14, 2019: Journal of Cardiology
Hideki Yano, Shigeo Horinaka, Manami Watahiki, Tomoko Watanabe, Toshihiko Ishimitsu
BACKGROUND: Use of the everolimus-eluting stent (EES) instead of the sirolimus-eluting stent (SES) has been shown to improve clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) out to 3 years. However, it is not known whether the differences in efficacy and safety outcomes remain constant throughout 5 years. METHODS: This was a retrospective, non-randomized, observational study. We followed 1460 consecutive patients undergoing PCI in our institutions from April 2005 to March 2012...
February 13, 2019: Journal of Cardiology
In-Soo Kim, Hyun-Jung Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong-Youn Kim, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
BACKGROUND: Amiodarone, which inhibits CYP2C9 and P-glycoprotein, is commonly prescribed with non-vitamin K antagonist oral anticoagulants (NOACs) and polypharmacy in high-risk atrial fibrillation (AF) patients. We studied efficacy and safety of NOACs in AF patients receiving amiodarone, P-glycoprotein inhibitor, or polypharmacy. METHODS: After a systematic database search (Medline, EMBASE, CENTRAL, SCOPUS, and Web of Science), four phase-III randomized trials comparing NOACs and warfarin in "with/without amiodarone," "with/without P-glycoprotein inhibitors," or "with/without multiple (≥5, polypharmacy) concomitant drugs" subgroups were included...
February 12, 2019: Journal of Cardiology
Takuya Nakahashi, Hayato Tada, Kenji Sakata, Yohei Yakuta, Yoshihiro Tanaka, Tadatsugu Gamou, Akihiro Nomura, Hidenobu Terai, Yuki Horita, Masatoshi Ikeda, Masanobu Namura, Masayuki Takamura, Kenshi Hayashi, Masakazu Yamagishi, Masa-Aki Kawashiri
BACKGROUND: Although concomitant peripheral artery disease in patients with acute coronary syndrome (ACS) has been considered as a high-risk subgroup with a greater incidence of bleeding after percutaneous coronary intervention (PCI), few data exist regarding the clinical utility of the ankle-brachial index (ABI) for predicting bleeding complications, which affects the subsequent outcome. METHODS: Eight hundred and twenty-four consecutive patients with ACS who underwent PCI and ABI examination were analyzed retrospectively...
February 7, 2019: Journal of Cardiology
Takanori Ikeda, Satoshi Ogawa, Takanari Kitazono, Jyoji Nakagawara, Kazuo Minematsu, Susumu Miyamoto, Yuji Murakawa, Makiko Takeichi, Yohei Ohashi, Yutaka Okayama, Toshiyuki Sunaya, Satoshi Yamanaka
BACKGROUND: Although the efficacy and safety of the factor Xa inhibitor rivaroxaban for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF) were shown in global and Japanese phase III clinical trials, safety and effectiveness data from unselected patients in everyday clinical practice are limited. The objective of the XAPASS (Xarelto Post-Authorization Safety & Effectiveness Study in Japanese Patients with Atrial Fibrillation) is to investigate the safety and effectiveness of rivaroxaban in Japanese real-world clinical practice...
February 7, 2019: Journal of Cardiology
Dong Oh Kang, Yoonjee Park, Ji Hoon Seo, Myung Ho Jeong, Shung Chull Chae, Tae Hoon Ahn, Won Young Jang, Woohyeun Kim, Eun Jin Park, Byoung Geol Choi, Jin Oh Na, Cheol Ung Choi, Eung Ju Kim, Seung-Woon Rha, Chang Gyu Park, Hong Seog Seo
BACKGROUND: Elevated high sensitivity C-reactive protein (hs-CRP) in acute myocardial infarction (AMI) patients undergoing percutaneous coronary intervention (PCI) has prognostic value for future cardiovascular events. This study aimed to ascertain a valid prognostic time-period for predicting cardiovascular outcome based on baseline hs-CRP in AMI patients undergoing successful PCI on statin therapy. METHODS: Overall, 4410 AMI patients were enrolled from the Korea Acute Myocardial Infarction-National Institutes of Health (KAMIR-NIH) registry...
February 7, 2019: Journal of Cardiology
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