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Clinical Neurophysiology

Clément Dondé, Charlotte Brevet-Aeby, Emmanuel Poulet, Marine Mondino, Jérôme Brunelin
OBJECTIVE: The Stroop effect performance reflects cognitive resistance to interference. We aimed to investigate the effect of a single transcranial random noise stimulation session (tRNS) applied over the dorsolateral prefrontal cortex (DLPFC) on the semantic Stroop effect and its resting electroencephalography (EEG) correlates (β/α ratio). METHODS: In a randomized, double-blind study, healthy volunteers were allocated to receive either one session of active tRNS (n=8) or one session of sham tRNS (n=11)...
March 28, 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Qiangfeng Zhao, Xiong Jiao, Yingying Tang, Shan Chen, Shanbao Tong, Jijun Wang, Junfeng Sun
OBJECTIVES: Studies have reported that depressed patients have difficulties in disengaging attention from negative information, but knowledge of the temporal characteristics of this disengagement is still rudimentary. Our objective is to reveal the temporal characteristics of attentional disengagement from emotional facial cues in depression. METHODS: We recruited 22 depressed patients and 22 healthy controls to participate in a cued target-response task with emotional facial expressions (happy, natural, and sad) as cues and three types of cue-target intervals (CTIs: 350ms, 1000ms, and 1500ms)...
March 19, 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Tuba Cerrahoğlu Şirin, Pınar Bekdik Şirinocak, Burcu Nuran Arkalı, Tuba Akıncı, Seher Naz Yeni
OBJECTIVE: To investigate the clinical importance of intermittent rhythmic delta activity (IRDA) in terms of accompanying electrophysiological findings on EEG and their association with IRDA. METHODS: We retrospectively assessed all EEG studies recorded in our institution from 2011 to 2017. Patients with intermittent rhythmic delta activity (IRDA) in EEGs were included. Clinical data were collected from charts of the patients with IRDA. RESULTS: We identified 69 EEGs with IRDA in 58 patients from a total of 18,625 EEG recordings...
January 31, 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Thierry Lelard, John Stins, Harold Mouras
Postural control is a motor skill that allows individuals to interact with their environment. Indeed, in all species, development of postural control is a prerequisite for acquiring further motor abilities. In humans, the maintenance of a bipedal posture plays an important role in interaction with the environment, as it provides a stable postural basis allowing upper limbs and hands to be used to manipulate objects. On the other hand, this bipedal posture induces a constraint in terms of balance, as individuals have to deal with a relatively small base of support enclosed by the surface of the two feet...
January 30, 2019: Clinical Neurophysiology
Hela Mrabet, Amel Mrabet, Nejib Hattab, Rachid Manai, Bechir Zouari
No abstract text is available yet for this article.
January 30, 2019: Clinical Neurophysiology
Pierre Decavel, Yoshimasa Sagawa
Gait disorders can be disabling in persons with multiple sclerosis (PMS). Different gait parameters have been used to evaluate gait disorders according to the International classification of functioning. Some authors have reported a direct relation between evaluations over short distances and long-term outcomes. This relationship is of interest for the purposes of clinical research, as it enables short-distance evaluations to be used as a primary endpoint for trials. However, these endpoints are not always particularly relevant for PMS, and furthermore, all evaluations do not present the same metrological characteristics, especially with regards to reproducibility...
January 30, 2019: Clinical Neurophysiology
Philippe Derambure, Jean-Pascal Lefaucheur
No abstract text is available yet for this article.
April 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Maenia Scarpino, Giovanni Lanzo, Maya Salimova, Francesco Lolli, Amedeo Del Vecchio, Cesarina Cossu, Maria Bastianelli, Brunella Occupati, Cecilia Lanzi, Stefano Pallanti, Aldo Amantini, Guido Mannaioni, Antonello Grippo
BACKGROUND: Cocaine use disorder (CUD) is very common and has psychological and physical consequences. Patients with CUD present hypoactivity of the prefrontal cortical area. Thus, excitatory repetitive transcranial magnetic stimulation (rTMS) targeting the premotor cortex/dorsolateral prefrontal cortex (PMC/DLPFC), given its ability to increase prefrontal area excitability and to modulate cortico-limbic activity, could result in a decrease in cocaine intake. METHODS: We designed a protocol for a monocentric, randomized, double-blind, placebo-controlled, parallel-group pilot trial, with the principal aim of assessing the efficacy of rTMS on the reduction of cocaine intake...
February 2019: Clinical Neurophysiology
Filippo Zappasodi, Gabriella Musumeci, Riccardo Navarra, Vincenzo Di Lazzaro, Massimo Caulo, Antonino Uncini
BACKGROUND AND OBJECTIVE: Application parameters of transcranial direct current stimulation (tDCS) for therapeutic purposes are relatively restricted. The aim of this study was to assess safety and effects on motor cortex excitability of an intensive anodal-tDCS protocol. METHODS: In 26 healthy subjects, five 15-minute anodal-tDCS sessions were delivered, at increasing time intervals, over 24hours. Safety was defined as absence of serious adverse events including brain tissue alterations on magnetic resonance imaging...
February 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Catarina Falcão de Campos, Pedro Viana, Isabel de Castro, José Castro, Mamede de Carvalho, Isabel Conceição
OBJECTIVES: Myasthenia gravis (MG) is an autoimmune disease associated with antibodies against the nicotinic muscle acetylcholine receptor (AChR) at the neuromuscular junction. Dysautonomia has been previously described in MG. Electrochemical skin conductance (ESC), assessed by Sudoscan® , is a non-invasive method that allows evaluation of sudomotor function. Since sweat glands are innervated by sudomotor, postganglionic, cholinergic sympathetic C-fibers, we hypothesized that ESC could be a reliable method for assessing autonomic dysfunction in MG...
February 2019: Clinical Neurophysiology
Jan Rosner, Janosch Rinert, Mario Ernst, Armin Curt, Michèle Hubli
INTRODUCTION: Cold evoked potentials (CEPs) represent a novel technique to assess the integrity of cold-specific pathways within the somatosensory system. So far an objective assessment of these pathways has not been implemented into the clinical routine. Specifically, CEPs may help to elucidate the pathophysiological underpinnings of altered cold processing in neurological diseases. OBJECTIVE: To test feasibility and test-retest reliability of CEPs within two cervical dermatomes, including recording sites in glabrous and hairy skin, in order to facilitate the transition into clinical practice...
February 2019: Clinical Neurophysiology
Jean-Pascal Lefaucheur
No abstract text is available yet for this article.
January 24, 2019: Clinical Neurophysiology
Hervé Devanne, Etienne Allart
No abstract text is available yet for this article.
January 24, 2019: Clinical Neurophysiology
Nathalie Chastan, Leslie M Decker
Parkinson's disease (PD) is known to have a long prodromal stage due to the degeneration of dopaminergic neurons of the substantia nigra pars compacta over the course of many years without clinical manifestations of PD. When the diagnosis is made, the neuropathological process is already well entrenched. Consequently, identifying individuals during this prodromal period could be very helpful for future trials of neuroprotective or disease-modifying therapies, which might slow or prevent the degeneration of dopaminergic neurons...
January 24, 2019: Clinical Neurophysiology
Claire Calmels
This paper depicts an approach aiming to allow individuals with orthopedic trauma injuries to optimize recovery and safely return to daily life. The core of this approach is motor simulation, used in complement to conventional physical rehabilitation methods. This paper provides recent scientific insights on the basis of motor simulation, discusses benefits of this approach in motor rehabilitation, and provides applied perspectives.
January 23, 2019: Clinical Neurophysiology
Frederic Viseux, Antoine Lemaire, Franck Barbier, Pascal Charpentier, Sebastien Leteneur, Philippe Villeneuve
Postural control requires constant and subconscious postural sway to manage balance and achieve postural stability. These movements of regulation are based in particular on cutaneous plantar information. The foot constitutes a functional whole that participates in the mechanisms of postural control and regulation. It represents the direct interface between the body and the ground during quiet standing, and plantar cutaneous information contributes to postural control. Upright balance mechanically depends on the gravitational torque produced by the forces of gravity and reaction of the ground...
January 10, 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Sophie Ng Wing Tin, Hela G Zouari, Samar S Ayache, Anne-Isabelle Tropeano, Christiane Ajzenberg, Jora Xhaxho, Abir Wahab, Jean-Pascal Lefaucheur, Alain Créange
OBJECTIVES: Metabolic abnormalities, such as, glycemic disorders and metabolic syndrome (GDMS) are one of the main causes of peripheral neuropathies. The objective of this study was to evaluate the impact of adding specific coaching care (CC) to standard care (SC) of therapeutic education based on lifestyle recommendations for neuropathies associated with GDMS. METHODS: This prospective randomized study included two groups of four patients (SC vs. CC) with examiners blinded to group allocation...
January 4, 2019: Neurophysiologie Clinique, Clinical Neurophysiology
Etienne Allart, Hervé Devanne, Arnaud Delval
Parietofrontal (PF) networks link the posterior parietal cortex to premotor and prefrontal areas, and are involved in the control of many motor and cognitive behaviors in healthy humans. In recent years, electrophysiological experiments have provided a better understanding of the functional specificity and temporal involvement of the PF networks' different components during the planning of visually guided upper limb movements. In particular, transcranial magnetic stimulation has been used to temporarily inactivate a cortical area (virtual lesions) or to assess connectivity using paired-pulse protocols))...
December 29, 2018: Clinical Neurophysiology
Yosra Cherni, Geneviève Girardin-Vignola, Laurent Ballaz, Mickael Begon
BACKGROUND: The Lokomat (by L-Force tool) allows the measurement of the maximum voluntary isometric torque (MVIT) at the knee and hip joints in a standing position, as close as possible to the posture adopted during walking. However, the reliability of this measurement in children with cerebral palsy (CP) remains unknown. The main goal of this study was to evaluate inter and intra-tester reliability of a novel tool (L-Force) in CP population. PROCEDURE: L-Force reliability was determined in 17 children with CP by two experienced therapists...
December 23, 2018: Clinical Neurophysiology
Julien Grandjean, Caroline Quoilin, Julie Duque
OBJECTIVES: Motor-evoked potentials (MEPs) to transcranial magnetic stimulation (TMS) show a profound suppression when elicited during the instructed-delay of reaction time (RT) tasks. One predominant hypothesis is that this phenomenon, called "preparatory inhibition", reflects the operation of processes that suppress motor activity to withhold prepared (but delayed) responses, a form of impulse control. In addition, a startling acoustic stimulus (SAS) - a loud and narrow sound - can trigger the release of prepared responses in RT tasks...
December 5, 2018: Clinical Neurophysiology
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