Juliana Nunes Ramos, Max Roberto Batista Araújo, Lincoln Oliveira Sant'Anna, Sérgio Bokermann, Carlos Henrique Camargo, Fernanda Diniz Prates, Cláudio Tavares Sacchi, Verônica Viana Vieira, Karoline Rodrigues Campos, Marlon Benedito Nascimento Santos, Marcus Vinícius Canário Viana, Vasco Azevedo, Flávia Figueira Aburjaile, Ana Luiza de Mattos-Guaraldi, Louisy Sanches Dos Santos
We present a case of skin lesion caused by nontoxigenic Corynebacterium diphtheriae. Genomic taxonomy analyses corroborated the preliminary identification provided by mass spectrometry. The strain showed a susceptible phenotype with increased exposure to penicillin, the first drug of choice for the treatment. An empty type 1 class integron carrying only the sul1 gene, which encodes sulfonamide resistance, was found flanked by transposases. Virulence factors involved in adherence and iron uptake, as well as the CRISPR-Cas system, were predicted...
November 21, 2023: European Journal of Clinical Microbiology & Infectious Diseases