Sebastián Marciano, Maria N Gutierrez-Acevedo, Sabrina Barbero, Lorena Del C Notari, Marina Agozino, Jose L Fernandez, Maria M Anders, Nadia Grigera, Florencia Antinucci, Orlando F Orozco Ganem, Maria D Murga, Daniela Perez, Ana Palazzo, Liria Martinez Rejtman, Ivonne G Duarte, Julio Vorobioff, Victoria Trevizan, Sofía Bulaty, Fernando Bessone, Marcelo Valverde, Martín Elizondo, José D Bosia, Silvia M Borzi, Teodoro E Stieben, Adriano Masola, Sebastian E Ferretti, Diego Arufe, Ezequiel Demirdjian, Maria P Raffa, Mirta Peralta, Hugo A Fainboim, Cintia E Vazquez, Pablo Ruiz, José E Martínez, Leandro A Heffner, Andrea Odzak, Melisa Dirchwolf, Astrid Smud, Manuel Mendizabal, Carla Bellizzi, Ana Martinez, Jesica Tomatis, Andres Bruno, Agñel Ramos, Josefina Pages, Silvina Tevez, Adrian C Gadano, Diego H Giunta
It is unclear whether norfloxacin predisposes to infections by multidrug-resistant organisms (MDROs). We aimed to evaluate if patients with cirrhosis receiving norfloxacin prophylaxis at the time of the diagnosis of bacterial infections were more likely to present a multidrug-resistant isolate than those without prophylaxis. This is a cross-sectional study of hospitalized patients with cirrhosis and bacterial infections from Argentina and Uruguay (NCT03919032) from September 2018 to December 2020. The outcome variable was a multidrug-resistant bacterial infection...
February 23, 2023: European Journal of Clinical Microbiology & Infectious Diseases