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Oncology (Williston Park, NY)

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https://read.qxmd.com/read/31219612/extending-adjuvant-endocrine-therapy-in-breast-cancer-who-what-why
#1
Shaveta Vinayak, Nancy E Davidson
Adjuvant endocrine therapy provides substantial benefit by reducing breast cancer recurrences and improving associated mortality in early-stage endocrine-responsive breast cancers (estrogen receptor- and/or progesterone receptor-positive). Residual risk of relapse, even after completion of 5 years of adjuvant endocrine therapy, has fueled development of extended therapy (beyond 5 years) trials. However, several questions remain when recommending extended adjuvant endocrine therapy, such as those concerning patient selection, agent of choice, use of biomarkers or clinical variables to assess residual risk of relapse, and duration of treatment...
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219611/breaking-new-ground-in-the-treatment-of-advanced-endometrial-cancer
#2
Vicky Makker
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219610/counterpoint-should-active-surveillance-be-used-for-gleason-3-4-prostate-cancer
#3
Ikenna Madueke, Michael R Abern
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219609/point-should-active-surveillance-be-used-for-gleason-3-4-prostate-cancer
#4
Abhishek Bhat, Sanoj Punnen Mas
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219608/considerations-when-initiating-neratinib-for-breast-cancer-how-to-prevent-and-treat-diarrhea
#5
Meagan S Barbee
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219607/preventing-gastric-cancer-development-by-inhibiting-the-virulence-of-h-pylori-infection
#6
Keith T Wilson
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219606/suicide-in-patients-with-cancer-identifying-the-risk-factors
#7
Daniel C McFarland, Leah Walsh, Stephanie Napolitano, Jody Morita, Reena Jaiswal
Thoughts of suicide while dealing with cancer are exceedingly common, though relatively few patients make a suicide attempt or complete suicide. Suicide rates among cancer patients are generally thought to be twice as high as that of the general population. However, patients with certain cancer types are at much higher risk for suicide; patients may also be more at risk at certain times during their cancer trajectory. While it is not possible to predict a suicidal act, key features identify those who should be screened more closely...
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219605/progressive-red-to-violaceous-papules-and-plaques-on-the-neck-and-abdominal-skin-of-a-70-year-old-woman
#8
Mehmet Sitki Copur, Karine Turcotte, Kai Fu, Pornchai Jonglertham
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219604/honing-in-on-subtypes-to-guide-more-individualized-treatment-of-soft-tissue-sarcoma
#9
Margaret Von Mehren
No abstract text is available yet for this article.
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31219603/evolving-strategies-for-the-management-of-braf-mutant-metastatic-colorectal-cancer
#10
Hey Min Lee, Van Morris, Stefania Napolitano, Scott Kopetz
Detection of the BRAF V600E mutation has important genetic, prognostic, and therapeutic implications for patients with metastatic colorectal cancer (mCRC), as it aids in the identification of a subgroup of patients who derive little benefit from standard treatments and have an extremely poor prognosis. Secondary analyses of BRAF V600E-mutated subsets from multiple randomized clinical trials have demonstrated a lack of therapeutic benefit and poor prognosis with conventional cytotoxic chemotherapy doublets, highlighting the need for novel effective treatments for this subpopulation...
June 19, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095720/hope-after-salvage-therapy-fails-novel-agents-for-relapsed-refractory-hodgkin-lymphoma
#11
Avyakta Kallam, Julie M Vose
Hodgkin lymphoma is a highly curable malignancy, with an excellent prognosis. However, around 10% to 25% of patients will have primary refractory or relapsed disease, despite using risk-adapted strategies. The standard of care for patients with relapsed/refractory Hodgkin lymphoma has been cytoreduction using salvage chemotherapy, followed by high-dose chemotherapy and autologous hematopoietic stem cell transplantation (AHSCT). Studies have shown that AHSCT produces a durable response rate of 50%, and that patients achieve a complete response with salvage chemotherapy...
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095719/the-role-of-primary-tumor-treatment-and-metastasis-directed-therapy-in-oligometastatic-prostate-cancer
#12
Abhinav Gupta, Thomas J Pugh, Elaine Lam, Alison D Sheridan, Sameer Nath
No abstract text is available yet for this article.
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095718/fda-approves-two-new-indications-and-dosage-form-for-pembrolizumab
#13
Traci DeVito, Naveed Saleh
No abstract text is available yet for this article.
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095717/state-of-cancer-research-around-the-globe
#14
Mehmet Sitki Copur
Cancer, the second leading cause of death globally, remains a significant challenge for societies, healthcare systems, and affected individuals worldwide. Adding to this challenge are complex disparities in access to and use of cancer care, basic and clinical research, and clinical trials, as well as disparities in cultural beliefs and genetics. To improve cancer treatment, it is essential that cancer investigators, cooperative groups, national research institutions, national governments, competent authorities, ethics committees, and pharmaceutical companies come together to strengthen global collaboration in cancer research...
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095716/evaluating-immunotherapy-in-nonmetastatic-colorectal-cancer
#15
Frank A Sinicrope
No abstract text is available yet for this article.
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095715/non-small-cell-lung-cancer-after-mantle-radiation-a-case-report-and-brief-review
#16
Carlos A Lopez, Emily S Tonorezos
Survivors of childhood and young adult cancer are at risk for developing subsequent malignant neoplasms, including lung cancer. As survival rates in this group continue to improve and patients enter later decades in life, determining the optimal surveillance and counseling strategies with regards to subsequent cancers remains a challenge. In this case report, we present a non-Hodgkin lymphoma survivor who was incidentally found to have non-small-cell lung cancer 30 years after undergoing treatment that included mantle radiation...
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/31095714/when-surgery-is-not-an-option-in-renal-cell-carcinoma-the-evolving-role-of-stereotactic-body-radiation-therapy
#17
Joseph Miccio, Kimberly Johung
Historically, radiation therapy has played a limited role in the management of renal cell carcinoma because early studies showed that it had no benefit in the neoadjuvant or adjuvant settings. Thus, radiation has typically been employed for only palliation of metastatic sites. As the ability to deliver conformal high-dose-per-fraction radiation became available, studies began to show excellent local control when treating oligometastatic sites of renal cell carcinoma with stereotactic body radiation therapy (SBRT)...
May 14, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/30990570/supporting-data-vs-patient-requests-in-oncology-when-the-two-don-t-coincide
#18
Mehmet Sitki Copur
Relationships between cancer patients and their oncologists flourish in a milieu of trust and goodwill. However, at times cancer patients may express strong preferences for medical tests, treatments, or other interventions that are not beneficial. Actively challenging these requests can be difficult and may threaten the patient-physician relationship. However, failure to discuss why specific diagnostic or therapeutic interventions are not appropriate may be harmful to the patient and lead to inefficient use or overuse of healthcare resources...
April 15, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/30990569/targeted-therapy-for-mutation-driven-metastatic-non-small-cell-lung-cancer-considerations-for-alk-rearranged-tumors
#19
Kathryn F Mileham, Mufti N Ahmad, Edward S Kim
No abstract text is available yet for this article.
April 15, 2019: Oncology (Williston Park, NY)
https://read.qxmd.com/read/30990568/multiple-myeloma-with-extramedullary-disease-a-challenging-clinical-dilemma
#20
Katherinee Morales-Chacón, María T Bourlon, Deborah Martínez-Baños, Jesús Delgado-de-la-Mora, Christianne Bourlon
No abstract text is available yet for this article.
April 15, 2019: Oncology (Williston Park, NY)
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