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Archives of Gynecology and Obstetrics

N de Gregorio, A de Gregorio, F Ebner, T W P Friedl, J Huober, R Hefty, M Wittau, W Janni, P Widschwendter
BACKGROUND: Pelvic exenterations are a last resort procedure for advanced gynecologic malignancies with elevated risks in terms of patients' morbidity. METHODS: This single-center analysis reports surgical details, outcome and survival of all patients treated with exenteration for non-ovarian gynecologic malignancies at our university hospital during a 13-year time period. We collected data regarding patients and tumor characteristics, surgical procedures, peri- and postoperative management, transfusions, complications, and analyzed the impact on survival outcomes...
April 22, 2019: Archives of Gynecology and Obstetrics
Ying Feng, Zihan Zhang, Tong Lou, Shuzhen Wang, Huimin Bai, Zhenyu Zhang
PURPOSE: The aim of this study was to assess the security of radical trachelectomy (RT) in the treatment of IA-IIA cervical carcinoma and conducted a new survey based upon the results of previous researches. METHODS: The PMC, PubMed, Web of Science, Cochrane and EMBASE databases were retrieved to collect prospective clinical controlled trials (CCTs) published from 1984 to 2018. The oncologic outcomes were evaluated by meta-analysis, trial sequence analysis (TSA) and statistical analysis...
April 22, 2019: Archives of Gynecology and Obstetrics
Liangliang Han, Peijing Yan, Liang Yao, Rong Liu, Ruixue Shao, Jian Liu, Xiaohong Chen, Liuli Wang, Kehu Yang, Tiankang Guo, Hailin Wang
OBJECTIVE: The aim of this study was to compare the safety and effectiveness of robotic hysterectomy (RH) with conventional laparoscopic hysterectomy (LH) for the treatment of cervical cancer using multivariate regressions. METHODS: We designed a retrospective single-center study and consecutively collected patients with cervical cancer from February 2014 to October 2017. Data extraction was performed by two independent researchers. The surgical outcomes include operative time, estimated blood loss, number of lymph nodes, time to first flatus, time to a full diet, time to remove drainage tube, length of hospital stay, and postoperative complication...
April 21, 2019: Archives of Gynecology and Obstetrics
Kristin Nicolaus, Dominik Bräuer, Robert Sczesny, Thomas Lehmann, Herbert Diebolder, Ingo B Runnebaum
PURPOSE: To determine risk factors for unexpected coexistent endometriosis in laparoscopic myomectomy for symptomatic uterine leiomyomas. METHODS: This was a single-centre, retrospective cohort study conducted at a University Women's Hospital with a certified endometriosis centre. Data were collected from patients with symptomatic uterine leiomyomas who underwent laparoscopic myomectomy. The main outcome measured in the study was the presence of histologically confirmed endometriosis...
April 21, 2019: Archives of Gynecology and Obstetrics
G Gitas, L Proppe, I Alkatout, A Rody, C Kotanidis, D Tsolakidis, S Baum
PURPOSE: The aim of this study was to estimate the accuracy of intra-operative frozen section (FS) diagnosis during hysterectomy for early-stage endometrial cancer (EC). METHODS: At the Department of Obstetrics and Gynecology, University of Luebeck, between 2009 and 2014, the intra-operative FS pathology of 164 patients with pre-operative endometrial curettage, showing G1 or G2 endometrioid EC at an early clinical stage (FIGO I-II), was compared retrospectively with the final paraffin section reports...
April 21, 2019: Archives of Gynecology and Obstetrics
Li-Dong Liu, Ying-Xin Pang, Xin-Rui Zhao, Rui Li, Cheng-Juan Jin, Jing Xue, Rui-Ying Dong, Pei-Shu Liu
PURPOSE: Curcumin (Cur), a yellow-colored dietary flavor from the plant (Curcuma longa), has been demonstrated to potentially resist diverse diseases, including ovarian cancer, but drug resistance becomes a major limitation of its success clinically. The key molecule or mechanism associated with curcumin resistance in ovarian cancer still remains unclear. The aim of our study was to investigate the effects of curcumin on autophagy in ovarian cancer cells and elucidate the underlying mechanism...
April 21, 2019: Archives of Gynecology and Obstetrics
Yu Zhao, Jianing Hu, Junmiao Xiang, Wenju Li, Xiujie Zhu, Min Zhao, Rongjiao Sun, Yue Hu, Qiong Zhang
PURPOSE: Laparoscopy and laparotomy are the two most common surgical options used to treat women with early-stage cervical cancer. This study aimed to examine the volume of hidden blood loss (HBL) between laparoscopy and laparotomy for cervical cancer and to identify its risk factors. METHODS: Sixty-one patients treated with laparotomy and 50 patients treated with laparoscopy were enrolled in this study. Their medical data were collected to calculate the HBL according to the Nadler and Gross formula, and its risk factors were identified by multiple linear regression analysis...
April 21, 2019: Archives of Gynecology and Obstetrics
G F Vercellino, E Erdemoglu, P Lichtenberg, M Z Muallem, R Richter, N R Abu-Rustum, M Plante, F Lécuru, S Greggi, B J Monk, S Sagae, C Denkert, M Keller, M Alhakeem, M Hellriegel, A M Dückelmann, V Chiantera, Jalid Sehouli
PURPOSE: To evaluate the practice patterns among centers and physicians worldwide regarding sentinel lymph node biopsies (SLNB) in cervical cancer (CC) patients. METHOD: A validated 35-item questionnaire regarding SLNB in CC supported by the Gynecologic Cancer Intergroup (GCIG), and sponsored by the North-Eastern German Society of Gynaecologic-Oncology (NOGGO) was sent to all major gynecological cancer societies across the globe for further distribution from October 2015 and continued for a period of 7 months...
April 21, 2019: Archives of Gynecology and Obstetrics
Ditte Gommesen, Ellen Aagaard Nohr, Henrik Christian Drue, Niels Qvist, Vibeke Rasch
PURPOSE: To assess risk factors for perineal tears, wound infection and dehiscence among primiparous women. METHODS: A prospective cohort study at four Danish hospitals (Odense, Esbjerg, Aarhus and Kolding) among 603 primiparous women sampled in three groups: 203 with none/labia/1st degree, 200 with 2nd degree, and 200 with 3rd/4th degree tears included between July 2015 and January 2018. Baseline data were obtained and a clinical examination of perineal wound healing was performed 11-21 days postpartum...
April 19, 2019: Archives of Gynecology and Obstetrics
Cheng Zeng, Jing Shang, Ao-Ming Jin, Pei-Li Wu, Xin Li, Qing Xue
PURPOSE: Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproductive technology (ART) treatment. However, there are limited data regarding the ability of the luteal GnRH antagonist cetrorelix to reduce the incidence of moderate and severe OHSS, and the mechanism remains unclear. Thus, we designed a study to assess the effectiveness of cetrorelix to prevent early moderate and severe OHSS in high-risk patients undergoing controlled ovarian stimulation for IVF/ICSI...
April 19, 2019: Archives of Gynecology and Obstetrics
Gokhan Boyraz, Yasin Durmus, Irfan Cicin, Oguzhan Kuru, Esra Bostanci, Gunsu Kimyon Comert, Hanifi Sahin, Hulya Ayik, Isin Ureyen, Alper Karalok, Mehmet Mutlu Meydanli, Mehmet Coskun Salman, Nejat Ozgul, Anil Onan, Tayup Simsek, Kunter Yuce, Taner Turan
PURPOSE: To investigate the clinico-pathological prognostic factors and treatment outcomes in patients with ovarian yolk sac tumors (YST). METHODS: A multicenter, retrospective department database review was performed to identify patients with ovarian YST who underwent surgery between 2000 and 2017 at seven Gynecologic Oncology Centers in Turkey. RESULTS: The study group consisted of 99 consecutive patients with a mean age of 23.9 years. While 52 patients had early stage (stage I-II) disease, the remaining 47 patients had advanced stage (stage III-IV) disease...
April 13, 2019: Archives of Gynecology and Obstetrics
Mehmet Sipahi, Mucahit Gunaydin, Tugrul Kesicioglu, Murat Usta, Berna Tezcan Yavuz, Canberk Tomruk
PURPOSE: To evaluate the effect of remote ischemic conditioning (RIC) on ovarian ischemia/reperfusion injury in a rat model. METHODS: A total of 36 Wistar albino rats with a body weight of 220-250 g were used for this study. Right adnexal torsion was performed for 180 min, and at the end of the period, the adnex was released and the abdomen was reclosed for 180 min for reperfusion. Torsion and detorsion procedures were applied to all rats except group 1 (sham, control)...
April 12, 2019: Archives of Gynecology and Obstetrics
Laurin Burla, David Scheiner, Eleftherios Pierre Samartzis, Stefan Seidel, Markus Eberhard, Daniel Fink, Andreas Boss, Patrick Imesch
PURPOSE: Comparison of preoperative magnetic resonance imaging (MRI) with intraoperative findings in patients with deep infiltrating endometriosis (DIE) by means of the ENZIAN score. METHODS: This retrospective two-center study includes 63 patients with deep infiltrating endometriosis, who underwent surgery between 2012 and 2016 at both the University Hospital of Zurich and the Cantonal Hospital of Schaffhausen. Inclusion criteria were a preoperative pelvic MRI and intraoperative or bioptic confirmation of DIE...
April 12, 2019: Archives of Gynecology and Obstetrics
Rubina Pandit, Vanita Jain, Rashmi Bagga, Pooja Sikka, Kajal Jain
OBJECTIVE: To assess the applicability of WHO Maternal Severity Score (MSS) and Maternal Severity Index (MSI) Model in near miss (NM) obstetric patients METHODS: It was a prospective observational study conducted at a tertiary health care center from July 2015 to Feb 2016. All patients fulfilling one or more WHO NM criteria were included. MSS and MSI were calculated for all NM patients on admission. They were then followed up till the final outcome (NM or death). Each NM parameter, system-wise MSS, total MSS and MSI were then associated with the final outcome...
April 11, 2019: Archives of Gynecology and Obstetrics
Mengchen Zhu, Shanshan Wang, Shanling Yi, Xiaomin Huang, Junan Meng, Li Chen, Haixiang Sun, Jianjun Zhou
BACKGROUND: Although exogenous follicle-stimulating hormone (FSH) has been used for decades and millions of cycles have been performed worldwide until now, criteria for selecting the proper FSH starting dose have not been clearly identified. The aim of this study was to elaborate a formula based on markers of ovarian reserve for the calculation of the appropriate starting dose of FSH. METHODS: A total of 931 patients underwent in vitro fertilization (IVF) treatment using long GnRH agonist protocol was retrospectively identified and reviewed...
April 11, 2019: Archives of Gynecology and Obstetrics
Nora K Schaal, Tanja Fehm, Josefine Albert, Martin Heil, Anya Pedersen, Markus Fleisch, Philip Hepp
PURPOSE: In developed countries, around 25% of all births involve labour induction. Studies have indicated that labour induction negatively influences the birth experience as well as the birth process. However, the impact of labour induction when only considering vaginal deliveries has not been studied yet, which was the purpose of the present study. METHODS: 186 women who gave birth vaginally took part in this prospective study. 95 women gave birth after spontaneous onset of labour (SL-group) and 91 women received a labour induction (LI-group)...
April 11, 2019: Archives of Gynecology and Obstetrics
Judit Lőrincz, Szabolcs Molnár, Attila Jakab, Tünde Herman, Singh Jashanjeet, Péter Török
AIM: Our purpose is to investigate if transcervical resection of endometrial polyps improves the fertility in ovulatory infertile women, and whether polyp histology, intrauterine location, and the technique of polypectomy have any influence on the pregnancy rates. METHODS: In this retrospective study, clinical data of 87 ovulatory infertile women who underwent hysteroscopy and polypectomy, and their 12-month follow-up have been analyzed. Subgroups according to the method of polyp removal (resectoscope or curettage), the polyp localization (utero-tubal, anterior, posterior, lateral, multiple) and the histological result were interpreted...
April 11, 2019: Archives of Gynecology and Obstetrics
Xuegong Ma, Yingmei Wang, Fengxia Xue
No abstract text is available yet for this article.
April 6, 2019: Archives of Gynecology and Obstetrics
Sindy Schug, Anja Baunacke, Maren Goeckenjan, Lars-Christian Horn, Gabriele Pretzsch, Gerolf Zimmermann, Henry Alexander
PURPOSE: Successful embryo implantation into the endometrium depends on embryonic characteristics and proper endometrial development. Reproductive medicine often focuses on embryo quality, whereas reliable diagnostic tests for endometrial receptivity are still needed. We previously found that human chorionic gonadotropin (hCG), one of the earliest proteins secreted by the embryo, was also expressed by the luteal phase endometrium around the implantation window. Here, we tested our hypothesis of endometrial hCG as an implantation marker...
April 6, 2019: Archives of Gynecology and Obstetrics
Daniela Di Martino, Bianca Masturzo, Sara Paracchini, Benedetta Bracco, Paolo Cavoretto, Federico Prefumo, Chiara Germano, Danila Morano, Flavia Girlando, Veronica Giorgione, Giulia Parpinel, Luisa Cariello, Federica Fusè, Massimo Candiani, Tullia Todros, Nicola Rizzo, Antonio Farina
PURPOSE: To compare the performance of the algorithms proposed by the Fetal Medicine Foundation in 2012 and BCNatal in 2013 in an Italian population. METHODS: A multicentric prospective study was carried out which included pregnancies at 11-13 weeks' gestation from Jan 2014 through May 2017. Two previously published algorithms were used for the calculation of the "a priori" risk of preeclampsia (based on risk factors from medical history) in each individual...
April 5, 2019: Archives of Gynecology and Obstetrics
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