Nicole Pochert, Mariella Schneider, Melitta B Köpke, Mathis Wild, Angelika Mattmer, Jacqueline Sagasser, Monika M Golas, Maggie Banys-Paluchowski, Aline Metz, Christian Hinske, Matthias Reiger, Udo Jeschke, Christian Dannecker, Avidan Neumann, Claudia Traidl-Hoffmann, Michael Untch, Thorsten Kühn, Nina Ditsch
PURPOSE: The development of a seroma after breast cancer surgery is a common postoperative complication seen after simple mastectomy and axillary surgery. We could recently demonstrate that breast cancer patients undergoing a simple mastectomy with subsequent seroma formation developed a T-helper cell increase within the aspirated fluid measured by flow cytometry. The same study revealed a Th2 and/or a Th17 immune response in peripheral blood and seroma fluid of the same patient. Based on these results and within the same study population, we now analyzed the Th2/Th17 cell associated cytokine content as well as the best known clinical important cytokine IL-6...
May 27, 2023: Archives of Gynecology and Obstetrics