Zhuo Zhang, Duoli Zhang, Fang Wang, Jiao Liu, Xian Jiang, Songyot Anuchapreeda, Singkome Tima, Zhangang Xiao, Suwit Duangmano
Malignant melanoma is the most lethal form of skin cancer, and its incidence rates are increasing in Europe, America, and Oceania countries. Despite immune checkpoint inhibitors, such as PD-1 inhibitors, have been shown to have significant therapeutic effects on malignant melanoma, many patients are unresponsive to these treatments, even emerged resistance. There is an urgent need to discover novel biomarkers that might distinguish resistant patients from responders. In this study, we used a series of bioinformatics analyses and experimental validation...
August 9, 2023: Molecular and Cellular Probes