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Journal of Laryngology and Otology

S H Yoon, M E Kim, H Y Kim, J S Lee, C H Jang
OBJECTIVE: This study evaluated tumour necrosis factor-α, interleukins 10 and 12, and interferon-γ levels, peripheral blood mononuclear cells, and clusters of differentiation 17c and 86 expression in unilateral sudden sensorineural hearing loss. METHODS: Twenty-four patients with unilateral sudden sensorineural hearing loss, and 24 individuals with normal hearing and no history of sudden sensorineural hearing loss (who were attending the clinic for other problems), were enrolled...
February 11, 2019: Journal of Laryngology and Otology
S Üstün Bezgin, T Çakabay, K Irak, M Koçyiğit, B Serin Keskineğe, S Giran Örtekin
OBJECTIVE: This study aimed to examine nasal mucociliary clearance time in patients with Helicobacter pylori infection. METHODS: Fifty patients who were newly diagnosed with H pylori infection using gastric biopsy in the gastroenterology out-patient clinic, and 50 age- and gender-matched healthy adults who were admitted to the otorhinolaryngology out-patient clinic, were included in this study. After an otorhinolaryngological examination (anterior rhinoscopy and nasal endoscopic examination), the nasal mucociliary clearance time of each subject was calculated using the saccharine test...
February 6, 2019: Journal of Laryngology and Otology
K Lau, M G Watson
BACKGROUND: Pharyngeal pouch surgical treatments can be carried out via an endoscopic or open approach. Injection of botulinum toxin into the cricopharyngeus was first described as an alternative treatment to the more invasive surgical procedures performed for cricopharyngeal dysfunction. It has not been previously described as a treatment option for pharyngeal pouch. OBJECTIVES: To compare operative time, average stay, complication rates and symptom control between endoscopic laser diverticulotomy, botulinum toxin injection and open procedures for pharyngeal pouch patients...
February 6, 2019: Journal of Laryngology and Otology
S Brophy-Williams, K Jarosz, J Sommer, A J Leach, P S Morris
BACKGROUND: Important ear problems can affect the outer ear, the middle ear and the inner ear. Globally, the greatest burden of disease is due to ear conditions that are associated with otorrhoea and hearing loss. METHODS: This study reviewed the literature on the prevention and treatment of common ear conditions that are most relevant to settings with high rates of ear disease and limited resources. The grading of recommendations assessment, development and evaluation ('GRADE') approach was utilised to assess interventions...
February 1, 2019: Journal of Laryngology and Otology
E Shamil, M J Rouhani, A C Panayi, J Lynch, J Tysome, N Jonas
OBJECTIVE: Adenotonsillectomy is frequently performed for obstructive sleep apnoea, but is associated with post-operative respiratory morbidity. This study assessed the effect of paediatric Otrivine (0.05 per cent xylometazoline hydrochloride) on post-operative respiratory compromise. METHODS: Paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea were included. The control group (n = 24) received no intervention and the intervention group (n = 25) received intra-operative paediatric Otrivine during induction using a nasal patty...
February 1, 2019: Journal of Laryngology and Otology
O Erdur, O Gul, K Ozturk
OBJECTIVE: To evaluate dysphagia and manometric changes in the upper oesophageal sphincter in patients with unilateral vocal fold paralysis. METHODS: Thirty patients with unilateral vocal fold paralysis due to vagal nerve paralysis scheduled for evaluation were enrolled in the study group; 24 healthy subjects were included in the control group. Upper oesophageal sphincter basal and residual pressure, relaxation time, and pharyngeal pressure values were evaluated by manometry...
February 1, 2019: Journal of Laryngology and Otology
E S Hogg, A J Kinshuck, N Littley, A Lau, S Tandon, J Lancaster
BACKGROUND: Simulation-based training has a fundamental role in medical education as it allows the learner to gain experience managing emergencies in a safe, controlled environment. METHODS: This 1-day course consisted of eight high-fidelity simulation scenarios, followed by a video-assisted debrief focusing on the technical and non-technical (communication skills, teamwork, leadership and situational awareness) aspects of managing ENT and head and neck emergencies...
February 1, 2019: Journal of Laryngology and Otology
R Y Hei, J Qin, S H Li
OBJECTIVE: To examine the diagnostic value of hyoid cephalometrics in predicting retroglossal obstruction severity in patients with obstructive sleep apnoea hypopnea syndrome. METHODS: Ninety-six obstructive sleep apnoea hypopnea syndrome patients diagnosed by polysomnography were recruited. Polysomnography was repeated with a nasopharyngeal tube after eliminating rhinal and palatopharyngeal obstruction. Cervical vertebra lateral films and hyoid cephalometric measurements were obtained, including the distances of the hyoid to the: mental tubercle, prevertebral plane, mental tubercle coronal plane and mental tubercle horizontal plane...
January 25, 2019: Journal of Laryngology and Otology
Y Tu, H Zhang, L Zhao, P Jin, X Zi, T Li, L Shi, L Zhi
BACKGROUND: Subcutaneous immunotherapy is an effective and safe treatment for allergic rhinitis and allergic asthma. Different symptom scores are used to evaluate the efficacy of subcutaneous immunotherapy in clinical trials. METHOD: A total of 58 allergic rhinitis patients sensitised to house dust mites, with or without mild asthma, were included. Symptom score, medication score, visual analogue scale score and quality of life were assessed before and after 6, 12 and 24 months of subcutaneous immunotherapy...
January 24, 2019: Journal of Laryngology and Otology
C Min, B Park, S Sim, H G Choi
OBJECTIVE: This study aimed to determine the relationship between laryngopharyngeal reflux and dietary modification. METHODS: A systematic review was conducted. The data sources for the study were PubMed, Embase, Cochrane Library and Web of Science. Articles were independently extracted by two authors according to inclusion and exclusion criteria. The outcome focus was laryngopharyngeal reflux improvement through diet or dietary behaviour. RESULTS: Of the 372 studies identified, 7 met our inclusion criteria...
January 16, 2019: Journal of Laryngology and Otology
N Goncalves, D Lubbe, S Peer, J Fagan
A novel, smartphone-based technique for endoscopic grommet insertion is presented.Results and conclusionThis method is both cost-effective and time-saving, offering a valuable alternative to the traditional microscope-based method in a resource-constrained setting.
January 14, 2019: Journal of Laryngology and Otology
M R Ahmed, A S Abou-Halawa, I H Ibrahim, R F Zittoon, E F Y Makary
BACKGROUND: Adenoid hypertrophy is a common cause of upper airway obstruction, and adenoidectomy is one of the most frequently performed operations in children. Topical nasal steroids can act directly on nasopharyngeal lymphoid tissue to decrease its reactive inflammatory changes and potentially reduce its size. OBJECTIVE: To study the light microscopic changes in adenoidal lymphoid tissue after one month of topical steroid use. METHODS: Twenty-six children with adenoid hypertrophy grade 3 scheduled for adenoidectomy were randomly divided into two equal groups: one group received mometasone furoate aqueous nasal spray (Nasonex) 100 mcg/day for four weeks, and a control group received nasal normal saline 0...
January 8, 2019: Journal of Laryngology and Otology
J Choi, H Dharmarajan, J Yu, K A Dunsky, T J Vece, E H Chiou, J Ongkasuwan
OBJECTIVE: This project compares the degree of tracheal collapse determined by rigid and flexible bronchoscopy in paediatric patients with tracheomalacia. METHODS: A total of nine patients with tracheomalacia underwent both rigid and flexible video bronchoscopy. All patients were breathing spontaneously. Cross-sectional images of the airway were processed using the ImageJ program and analysed via colour histogram mode technique in order to delineate the luminal area...
December 19, 2018: Journal of Laryngology and Otology
M C F Smith, C Huins, M Bhutta
Surgery for chronic suppurative otitis media performed in low- and middle-income countries creates specific challenges. This paper describes the equipment and a variety of techniques that we find best suited to these conditions. These have been used over many years in remote areas of Nepal.Results and conclusionExtensive chronic suppurative otitis media is frequently encountered, with limited pre-operative investigation or treatment possible. Techniques learnt in better-resourced settings with good follow up need to be modified...
December 19, 2018: Journal of Laryngology and Otology
R Lawrence, E Jeffs, Deh Hartley
OBJECTIVE: Facial nerve paresis is rare following cochlear implantation. Mechanisms underlying delayed-onset facial paresis are poorly understood. This paper describes the case of a patient who developed facial nerve paresis three years after implantation. A literature review was performed with the aim of identifying any similar cases. METHODS: The patient case is reported, and the literature reviewed using PubMed, Embase and Ovid databases. RESULTS: The literature review revealed that the vast majority of delayed-onset facial nerve paresis cases occur within the first month of implantation...
December 19, 2018: Journal of Laryngology and Otology
G Tirelli, N Gardenal, A Gatto, E Quatela, G C Del Piero
BACKGROUND: Immunoglobulin G4 related disease is a recently described systemic syndrome. The head and neck region is the second most common site for presentation after the pancreas. METHODS: PubMed and the Cochrane Library were searched from 1995 to July 2017 for all the studies on immunoglobulin G4 related disease diagnosed in the head and neck compartment. Patient-specific data were extracted and basic statistical analysis was performed. RESULTS: Ninety-one patients were identified...
December 18, 2018: Journal of Laryngology and Otology
A Doğan, N Bayar Muluk, N Asal, M H Şahan, M Inal, Ö Gündüz, O K Arıkan
OBJECTIVE: To investigate olfactory bulb volume and olfactory sulcus depth in patients with Behçet's disease, using magnetic resonance imaging. METHODS: Cranial magnetic resonance imaging scans of 27 adults with Behçet's disease (10 males and 17 females) and 27 healthy controls were examined. Olfactory bulb volume and olfactory sulcus depth were measured on coronal, T2-weighted, spectral pre-saturation with inversion recovery sequences. RESULTS: Bilateral olfactory bulb volume and right-sided olfactory sulcus depth were significantly lower in the Behçet's disease group than in the control group (p < 0...
December 18, 2018: Journal of Laryngology and Otology
M F Bhutta
BACKGROUND: There is poor availability of ear and hearing services globally, because of a lack of infrastructure, funding, equipment and appropriately trained personnel. When deciding upon delivery of ear and hearing services, an approach based upon community assessment is advocated, with subsequent asset mapping and acquisition. OBJECTIVES: Some of the challenges to delivery of care in resource-constrained or remote environments are acknowledged, with discussion of several existing models of service delivery, and their advantages and disadvantages...
December 18, 2018: Journal of Laryngology and Otology
K Sato, S Chitose, F Sato, H Umeno
BACKGROUND: In order to improve a large posterior glottal gap and/or aspiration, injections of augmentation substances should not only be administered at the mid-membranous vocal fold in the thyroarytenoid muscle, but also at the cartilaginous portion of the vocal fold to make adduction arytenopexy possible. METHOD: Ten adult human larynges were investigated using the whole-organ serial section technique. RESULTS: Vertical thickness of the posterior aspect of the thyroarytenoid muscle was relatively thin (3...
December 18, 2018: Journal of Laryngology and Otology
T Hardcastle, A Wood
OBJECTIVE: To examine the impact of temporal bone virtual reality surgical simulator use in the undergraduate otorhinolaryngology curriculum. METHODS: Medical students attended a workshop involving the use of a temporal bone virtual reality surgical simulator. Students completed a pre-workshop questionnaire on career interests. A post-workshop questionnaire evaluated the perceived usefulness and enjoyment of the virtual reality surgical simulator experience, and assessed changes in their interest in ENT...
November 20, 2018: Journal of Laryngology and Otology
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