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https://read.qxmd.com/read/31000833/long-term-natural-history-of-idiopathic-epiretinal-membranes-with-good-visual-acuity
#1
Kieu-Yen Luu, Tynisha Koenigsaecker, Amirfarbod Yazdanyar, Lekha Mukkamala, Blythe P Durbin-Johnson, Lawrence S Morse, Ala Moshiri, Susanna S Park, Glenn Yiu
BACKGROUND/OBJECTIVES: To evaluate the long-term progression of idiopathic epiretinal membranes (iERMs) with good baseline visual acuity, and to identify predictors of visual decline. DESIGN: Retrospective case series SUBJECTS METHODS: We reviewed records of 145 eyes with iERM and best-corrected visual acuity (BCVA) of 20/40 or greater at presentation, including BCVA, lens status, and central macular thickness (CMT) at yearly visits; as well as anatomic biomarkers including vitreomacular adhesion, pseudohole, lamellar hole, intraretinal cysts, disorganization of the inner retinal layers (DRIL), and disruption of outer retinal layers...
April 19, 2019: Eye
https://read.qxmd.com/read/30996339/tyrosinase-tyr-gene-sequencing-and-literature-review-reveals-recurrent-mutations-and-multiple-population-founder-gene-mutations-as-causative-of-oculocutaneous-albinism-oca-in-pakistani-families
#2
Muhammad Shakil, Gaurav V Harlalka, Shamshad Ali, Siying Lin, Ilaria D'Atri, Shabbir Hussain, Abdul Nasir, Muhammad Aiman Shahzad, Muhammad Ikram Ullah, Jay E Self, Emma L Baple, Andrew H Crosby, Saqib Mahmood
PURPOSE: To investigate eight previously unreported Pakistani families with genetically undefined OCA for mutations in TYR. METHODS: Sanger sequencing of TYR has been performed in eight families with OCA phenotype. Mutation analysis was performed to establish the pathogenic role of novel mutation. Bioinformatics analysis was performed to predict the structural and functional impacts on protein due to the mutation. RESULTS: In this study, we identified six likely pathogenic variants of TYR (c...
April 17, 2019: Eye
https://read.qxmd.com/read/30996338/visual-function-questionnaire-as-an-outcome-measure-for-homonymous-hemianopia-subscales-and-supplementary-questions-analysis-from-the-vision-trial
#3
Fiona J Rowe, Lauren R Hepworth, Elizabeth J Conroy, Naomi E A Rainford, Emma Bedson, Avril Drummond, Marta García-Fiñana, Claire Howard, Alex Pollock, Tracey Shipman, Caroline Dodridge, Stevie Johnson, Carmel Noonan, Catherine Sackley
BACKGROUND: We conduct supplementary analyses of the NEI VFQ-25 data to evaluate where changes occurred within subscales of the NEI VFQ-25 leading to change in the composite scores between the three treatment arms, and evaluate the NEI VFQ-25 with and without the Neuro 10 supplement. METHODS: A prospective, multicentre, parallel, single-blind, three-arm RCT of fourteen UK acute stroke units was conducted. Stroke survivors with homonymous hemianopia were recruited...
April 17, 2019: Eye
https://read.qxmd.com/read/30996337/a-hidden-footprint-embryological-origins-of-age-related-macular-degeneration
#4
EDITORIAL
Glen Jeffery, Sobha Sivaprasad
No abstract text is available yet for this article.
April 17, 2019: Eye
https://read.qxmd.com/read/30988421/comparison-between-patient-reported-outcomes-after-enucleation-and-proton-beam-radiotherapy-for-uveal-melanomas-a-2-year-cohort-study
#5
Laura Hope-Stone, Stephen L Brown, Heinrich Heimann, Bertil Damato
BACKGROUND: Uveal melanomas affect 2-8 per million Europeans each year. Approximately 35%, are treated by enucleation. Proton beam radiotherapy (PBR) can be an eye-conserving alternative to enucleation for patients who wish to retain the eye. Both treatments have adverse effects, and it is difficult for clinicians and patients to make fully informed choices between them because the relative effects of enucleation and PBR on patient-reported outcomes are unknown. METHODS: We compared differential effects of enucleation and PBR on patient-reported outcomes on the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Ophthalmological module (EORTC QLQ- OPT30) in a consecutive sample of 115 treated patients ~ 6, 12 and 24 months after diagnosis...
April 15, 2019: Eye
https://read.qxmd.com/read/30976073/national-incidence-of-eyelid-cancer-in-ireland-2005-2015
#6
Clare Quigley, Sandra Deady, Emily Hughes, Elizabeth McElnea, Lina Zgaga, Shivona Chetty
AIMS: We report on the incidence of cutaneous eyelid tumours in Ireland over the 11-year-period from 2005 to 2015, we identify associations between demographic factors and cutaneous eyelid tumour risk. METHODS: Skin cancers, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), melanoma, and other cancers, located on the eyelid or canthus according to ICD-10 coding, as registered by the National Cancer Registry of Ireland (NCRI), were captured from the period 2005 to 2015...
April 11, 2019: Eye
https://read.qxmd.com/read/30976072/two-stage-aqueous-drainage-tube-implant-with-pericardial-graft-patch
#7
LETTER
Minak Bhalla, Sheila Luk, Rohit Jolly, Faisal Ahmed
No abstract text is available yet for this article.
April 11, 2019: Eye
https://read.qxmd.com/read/30971816/risk-of-aphakic-glaucoma-after-pars-plana-lensectomy-with-and-without-removal-of-the-peripheral-lens-capsule
#8
M Stech, B Grundel, M Daniel, D Böhringer, L Joachimsen, N Gross, C Wolf, H Link, U Gilles, W A Lagrèze
BACKGROUND: The etiology of aphakic glaucoma is unclear. It has been suggested that remaining lens epithelium releases cytokines transducing trabecular meshwork cells. Therefore, we compared two cohorts of children undergoing lensectomy. In cohort 1, the entire lens including its capsule was removed, in cohort 2 the peripheral lens capsule was left intact, also to facilitate secondary intraocular lens implantation later on. METHODS: We included children with uni- or bilateral congenital cataract who underwent lensectomy during the first year of life with subsequent contact lenses fitting...
April 10, 2019: Eye
https://read.qxmd.com/read/30971815/test-performance-of-optical-coherence-tomography-angiography-in-detecting-retinal-diseases-a-systematic-review-and-meta-analysis
#9
Livia Faes, Nicolas S Bodmer, Silvan Locher, Pearse A Keane, Konstantinos Balaskas, Lucas M Bachmann, Reinier O Schlingemann, Martin K Schmid
OBJECTIVE: To investigate the diagnostic accuracy of optical coherence tomography angiography (OCTA) in detecting vascular characteristics of chorio-retinal disease. METHODS: Evidence acquisition: We searched Web of Science, Scopus, and Medline by the citation of references and complemented these electronic searches by checking the list of references of included and review articles. Screening, selection, assessment, and extraction was performed in parallel by two authors...
April 10, 2019: Eye
https://read.qxmd.com/read/30971814/optical-coherence-tomography-angiography-of-types-1-and-2-choroidal-neovascularization-in-age-related-macular-degeneration-during-anti-vegf-therapy-evaluation-of-a-new-quantitative-method
#10
Henrik Faatz, Marie-Louise Farecki, Kai Rothaus, Frederic Gunnemann, Matthias Gutfleisch, Albrecht Lommatzsch, Daniel Pauleikhoff
PURPOSE: The aim of this pilot study was to test whether mathematical parameters of the vascular morphology of choroidal neovascularization (CNV) can be used as biomarkers and to investigate how these parameters change during anti-vascular endothelial growth factor (VEGF) therapy. METHODS: Treatment-naive CNV in exudative age-related macular degeneration (AMD) was diagnosed in 28 patients. OCT-angiography (OCT-A) (Avanti/FA Optovue) performed before and after anti-VEGF therapy...
April 10, 2019: Eye
https://read.qxmd.com/read/30971813/correlation-between-structural-progression-in-glaucoma-and-obstructive-sleep-apnea
#11
Yuan-Yao Fan, Wei-Wen Su, Chun-Hsiu Liu, Henry Shen-Lih Chen, Shiu-Chen Wu, Shirley H L Chang, Kuan-Jen Chen, Wei-Chi Wu, Ning-Hung Chen, Hsueh-Yu Li, Ming-Hui Sun
BACKGROUND/OBJECTIVES: To investigate the correlation between obstructive sleep apnea (OSA) severity and the structural and functional progression in patients with glaucoma. SUBJECTS/METHODS: This retrospective comparative cohort study included subjects from the polysomnography database in Chang Gung Memorial Hospital between June 1, 2009, and June 1, 2017, by identifying patients who had received diagnoses of primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), or glaucoma suspect...
April 10, 2019: Eye
https://read.qxmd.com/read/30967643/biotherapeutics-and-immunogenicity-ophthalmic-perspective
#12
Ashish Sharma, Nilesh Kumar, Baruch D Kuppermann, Bandello Francesco, Anat Loewenstein
No abstract text is available yet for this article.
April 9, 2019: Eye
https://read.qxmd.com/read/30962545/the-potential-and-value-of-objective-eye-tracking-in-the-ophthalmology-clinic
#13
Rosie Clark, James Blundell, Matt J Dunn, Jonathan T Erichsen, Mario E Giardini, Irene Gottlob, Chris Harris, Helena Lee, Lee Mcilreavy, Andrew Olson, Jay E Self, Valldeflors Vinuela-Navarro, Jonathan Waddington, J Margaret Woodhouse, Iain D Gilchrist, Cathy Williams
No abstract text is available yet for this article.
April 8, 2019: Eye
https://read.qxmd.com/read/30962544/children-s-hospital-of-philadelphia-score-to-predict-severe-retinopathy-in-indian-preterm-infants
#14
Suraj Doshi, Saumil Desai, Ruchi Nanavati, Nandkishor Kabra, Snehal Martin
BACKGROUND: Retinopathy of Prematurity (ROP) screenings are expensive and entail heavy workload. Predictive models using postnatal weight gain reduces the number of ophthalmological examinations. The objective was to validate Children's Hospital of Philadelphia (CHOP) score to predict severe ROP in resource limited settings. METHODS: Prior to ophthalmic examination, the CHOP score was calculated to predict severe ROP (point estimate = 0.014) in 191 preterm infants...
April 8, 2019: Eye
https://read.qxmd.com/read/30962543/foveal-and-parafoveal-choroidal-thickness-pattern-measuring-by-swept-source-optical-coherence-tomography
#15
Pear Pongsachareonnont, Thanapong Somkijrungroj, Buravej Assavapongpaiboon, Theerada Chitamara, Maytavee Chuntarapas, Disorn Suwajanakorn
OBJECTIVE: To evaluate the choroidal thickness (CT) in foveal and parafoveal regions in Thai adults using swept-source optical coherence tomography (SS-OCT). METHODS: We enrolled healthy volunteers ≥18 years of age from King Chulalongkorn Memorial Hospital, Thailand, during September 2015 to March 2016. Optical coherence tomography (OCT) of the macula was performed, and subfoveal CT was measured manually using a line scan. Average thicknesses of retinal and choroidal layers in regions of the Early Treatment Diabetic Retinopathy Study grid were measured automatically...
April 8, 2019: Eye
https://read.qxmd.com/read/30952958/the-practice-patterns-in-the-management-of-sebaceous-carcinoma-of-the-eyelid-in-the-asia-pacific-region
#16
Janice J C Cheung, Bita Esmaeli, Stacey C Lam, Tracey Kwok, Hunter K L Yuen
PURPOSE: To determine the practice patterns of ophthalmic plastic surgeons regarding the management of eyelid sebaceous carcinoma (SC). METHODS: An electronic survey was distributed to oculoplastic surgical colleagues in the Asia Pacific region requesting clinical information and treatment approaches to SC. RESULTS: The responses from 192 respondents from the Asia Pacific region was included and analyzed in this study. For initial diagnosis, most surgeons selected incisional biopsy (55%), followed by complete excision (35%)...
April 5, 2019: Eye
https://read.qxmd.com/read/30952957/long-term-outcomes-of-patients-with-myopic-traction-maculopathy-after-phacoemulsification-for-incident-cataract
#17
Lei Cai, Zhongcui Sun, Diwen Guo, Qi Fan, Xiangjia Zhu, Jin Yang, Yi Lu
PURPOSE: To evaluate the long-term effect of cataract surgery on highly myopic patients with myopic traction maculopathy (MTM) and the risk factors associated with MTM progression. METHODS: Highly myopic patients with cataract and MTM were included. Phacoemulsification surgery was performed on patients who had vision loss below 20/63 and were willing to operation. Exclusion criteria included full thickness macular hole, foveal/retinal detachment, history of vitreoretinal surgery, myopic choroidal neovascularization, macular chorioretinal atrophy, peripheral lattice degeneration, incomplete follow up, or intraoperative complications...
April 5, 2019: Eye
https://read.qxmd.com/read/30944463/diagnosis-and-surgical-management-of-orbital-sparganosis
#18
Qing Xia, Jianhua Yan
PURPOSE/BACKGROUND: Orbital sparganosis represents an extremely rare condition with only a few cases being reported in literature. Here we describe cases of orbital sparganosis, including their etiology, clinical findings, and surgical outcomes. PATIENTS AND METHODS: A retrospective review was performed on patients with orbital sparganosis, who were treated at Zhongshan Ophthalmic Center, of Sun Yat-sen University, China between 2000 and 2012. RESULTS: Five patients (three males and two females, one right orbit and four left orbits) were identified...
April 3, 2019: Eye
https://read.qxmd.com/read/30944462/direct-eyelid-defect-closure-a-prospective-study-of-functional-and-aesthetic-outcomes
#19
Vladimir T Thaller, Simon N Madge, W Chan, I Vujic, F Jazayeri
BACKGROUND/OBJECTIVES: Direct closure (DC) of eyelid defects has been retrospectively shown to give excellent outcomes. We present prospective outcome data as further evidence to promote its wider use. SUBJECTS AND METHODS: A consecutive, unselected, series of patients undergoing eyelid tumour resection was studied prospectively. DC was attempted at the time of biopsy in all of them. If DC proved impossible, delayed reconstruction using other techniques was later performed...
April 3, 2019: Eye
https://read.qxmd.com/read/30944461/intra-lenticular-lens-aspiration-in-paediatric-cases-with-anterior-dislocation-of-lens
#20
Pranita Sahay, Prafulla K Maharana, Nawazish Shaikh, Siddhi Goel, Rajesh Sinha, Tushar Agarwal, Namrata Sharma, Jeewan S Titiyal
PURPOSE: To assess the outcomes of intra-lenticular lens aspiration (ILLA) in paediatric cases with anterior dislocation of lens. METHODS: A retrospective review of medical records of cases with anterior dislocation of the lens in children (age < 16 years) that underwent ILLA between June 2017 and May 2018 was performed. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and anterior segment findings were noted at presentation and follow-up...
April 3, 2019: Eye
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