Yoshitaka Hashimoto, Takuro Okamura, Ryo Bamba, Yuta Yoshimura, Chihiro Munekawa, Ayumi Kaji, Akane Miki, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Takakuwa, Ryoichi Sasano, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui
This study investigated the effects of miso, a traditional fermented soybean food in Japan, on muscle mass atrophy. Eight week old male C57BL/6J mice were fed high fat/high sucrose diet with or without miso for 12 weeks. A miso diet increased soleus muscle weights ( p <0.05) and reduced intraperitoneal glucose tolerance and insulin tolerance ( p <0.05). The miso diet downregulated the Tnfα and Ccl2 expression, related to inflammation, and Trim63 and Fbxo32 expression, related to muscle atrophy, in the soleus muscle ( p <0...
January 2024: Journal of Clinical Biochemistry and Nutrition