Yixin Sun, Ziming Li, Xiaoyu Qi, Binghan Wang, Nanze Yu, Jiuzuo Huang, Wenyun Ting, Xiao Long
This review aims to assess the efficacy and safety of laser therapy in managing scars resulting from cleft lip and/or palate (CL/P) repair surgeries, as well as to determine the optimal timing for intervention. A systematic search was conducted across four databases using a predefined search strategy. Studies included were randomized controlled trials, non-randomized studies, and case series focusing on laser therapy for CL/P scars. Data extraction and analysis were performed using Revman Software. A total of two randomized controlled trials, four non-randomized studies, and three case series were included in the analysis...
June 20, 2024: Lasers in Medical Science
Vanessa Hafez, Doaa Mahgoub, Elsayed Mohamed Ali Satour, Marina Mozeih Shaker Mikhail, Mona El-Kalioby
Striae distensae are common dermatological complaint. Cold laser using low-level light/laser therapy (LLLT) offers healing and analgesic effects and was not yet compared to 'hot lasers' efficacy. Study objective: to assess the efficacy and safety of LLLT in the management of stria alba compared to fractional carbon dioxide (FCO2 ) laser alone and to the combined use of both devices. Thirty patients with stria alba were randomized to receive either LLLT using diode 808 nm; 8-12 sessions, 2-3 sessions weekly (Group A) or FCO2 laser; 2 monthly sessions (Group B) or combined both devices simultaneously (Group C)...
June 19, 2024: Lasers in Medical Science
Mohammad Bayat, Mehrdad Asgari, Mohammad-Amin Abdollahifar, Ali Moradi, Fatemeh Zare, Reza Kouhkheil, Rouhallah Gazor, Ali Ebrahiminia, Zahra Shahnazary Karbasaraea, Sufan Chien
Orthopedic surgeons face a significant challenge in treating critical-size femoral defects (CSFD) caused by osteoporosis (OP), trauma, infection, or bone tumor resections. In this study for the first time, the application of photobiomodulation (PBM) and bone marrow mesenchymal stem cell-conditioned medium (BM-MSC-CM) to improve the osteogenic characteristics of mineralized bone scaffold (MBS) in ovariectomy-induced osteoporotic (OVX) rats with a CSFD was tested. Five groups of OVX rats with CSFD were created: (1) Control (C); (2) MBS; (3) MBS + CM; (4) MBS + PBM; (5) MBS + CM + PBM...
June 18, 2024: Lasers in Medical Science
Sucharita Banerjee, Mangesh V Pantawane, Narendra B Dahotre
Frequently orthopedic surgeries require mechanical drilling processes especially for inserted biodegradable screws or removing small bone lesions. However mechanical drilling techniques induce large number of forces as well as have substantially lower material removal rates resulting in prolong healing times. This study focuses on analyzing the impact of quasi-continuous laser drilling on the bone's surface as well as optimizing the drilling conditions to achieve high material removal rates. An ex-vivo study was conducted on the cortical region of desiccated bovine bone...
June 15, 2024: Lasers in Medical Science
Alarifi Abdulaziz, Moataz Mohamed El-Kholy, Sherif Samir Bushra, Sara Mohamed Ali, Karim A Shehab
The risk of enamel deterioration that frequently coexists with debonding of orthodontic teeth brackets elevates the mandate for finding an optimum approach for debonding them without harmful effects. This in-vitro study is intended to compare the effects of two different laser modes (scanning and circular) and a conventional method on the enamel surface after debonding orthodontic brackets. 66 extracted premolars were assigned into 3 groups. After that, light-cure composite resin was used to attach the ceramic brackets to the teeth...
June 13, 2024: Lasers in Medical Science
Gabriel Pereira Nunes, Renata de Oliveira Alves, Matheus Henrique Faccioli Ragghianti, Tamires Passadori Martins, Alexandre Henrique Dos Reis Prado, Larissa Pereira Nunes, Maria Clara Faria Poli, Arles Naisa Amaral Silva, Francine Benetti
The aim of this systematic review and meta-analysis (SRM) was to evaluate the effectiveness of the adjunctive use of antimicrobial photodynamic therapy (aPDT) in non-surgical periodontal treatment (NSPT) in subjects with Human Immunodeficiency Virus (HIV) and periodontitis. This SRM was registered in PROSPERO (CRD42023410180) and followed the guidelines of PRISMA 2020. Searches were performed in different electronic databases. Risk of bias was performed using the Cochrane Risk of Bias tool (RoB 2.0) for randomized clinical trials (RCT)...
June 12, 2024: Lasers in Medical Science
Shushu Xu, Zhongjing Lin, Yanzhi Guo, Ping Huang, Shouyue Huang, Yisheng Zhong
PURPOSE: To investigate the diagnostic ability of retinal superficial vasculature evaluation by optic coherence tomography angiography (OCTA) combined with visual field (VF) testing for early primary open-angle glaucoma (POAG). PATIENTS AND METHODS: In this cross-sectional study, 84 participants were included, including 11 in the ocular hypertension (OHT) group, 11 in the preperimetric POAG (pre-POAG) group, 29 in the early POAG group and 33 in the control group...
June 11, 2024: Lasers in Medical Science
Lasarus Mitrofanoff, Susanna Marini, Leonardo Marini
Q-switched (QS) Nd: YAG lasers are frequently utilised light sources for tattoo removal due to their precise micro-confined photo-acoustic interaction with exogenous and endogenous pigments. In order to achieve optimal results, several treatment sessions are usually required. However, the number of sessions depend on tattoo size, design complexity, pigment quantity within dermal layers, and anatomical location. Higher energy settings have often been used to reduce treatment sessions to a minimum however, this approach may lead to possible post-laser skin complications such as pathological wound healing...
June 11, 2024: Lasers in Medical Science
Natalia Romanenko, Svetlana Tarasenko, Albert Davtyan, Natalia Serezhnikova, Sofiko Djidjavadze, Alexandre Derevyankin, Ekaterina Shchetinina, Anton Deryugin, Anastasiya Burlak
In clinical practice, an innovative laser technology that provides contactless preparation of soft tissues with a wavelength of 445 nm has been introduced. This study aimed to investigate the morphological changes in the oral mucosa when exposed to laser radiation at a wavelength of 445 nm in the ablation mode.An experimental study was conducted to analyze the dynamics of reparative regeneration in the wound caused by that particular type of radiation, utilizing the procedure of lower lip frenuloplasty as an illustration...
June 8, 2024: Lasers in Medical Science
Kentaro Sueoka, Taiichiro Chikama, Koichiro Shinji, Yoshiaki Kiuchi
The aim of this study was to compare two types of light irradiation devices for antimicrobial photodynamic therapy (aPDT). A 660-nm light-emitting diode (LED) and a 665-nm laser diode (LD) were used for light irradiation, and 0.1 mg/L TONS 504, a cationic chlorin derivative, was used as the photosensitizer. We evaluated the light attenuation along the vertical and horizontal directions, temperature rise following light irradiation, and aPDT efficacy against Staphylococcus aureus under different conditions: TONS 504 only, light irradiation only, and TONS 504 with either LED (30 J/cm2 ) or LD light irradiation (continuous: 30 J/cm2 ; pulsed: 20 J/cm2 at 2/3 duty cycle, 10 J/cm2 at 1/3 duty cycle)...
June 5, 2024: Lasers in Medical Science
Ibadulla Mirzayev, Ahmet Kaan Gündüz, Ahmet Ergin
PURPOSE: To investigate the swept-source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA) findings in circumscribed choroidal hemangioma (CCH) before and after treatment with transpupillary thermotherapy (TTT). METHODS: The clinical records of 21 eyes having CCH imaged with SS-OCT/SS-OCTA between September 2018 and December 2022 were evaluated. RESULTS: SS-OCT examination in CCH showed dome-shaped appearance (100%), choroidal shadowing (100%), expansion of choroidal structures (100%), subretinal fluid (66...
June 5, 2024: Lasers in Medical Science
Ivânia Soares, Inês Pereira Amaral, Madalena Pupo Correia, Rita Travassos, Paulo Filipe
This article explores the intricacies of laser surgery, acknowledging inherent risks and complications. Patients with higher Fitzpatrick phototypes, characterized by unique biological traits, face heightened vulnerability during laser treatments. Limited experience with darker skin tones necessitates a higher level of laser expertise and a conservative approach. The study aims to comprehensively review laser therapy's side effects and complications, with a specific focus on Fitzpatrick phototypes IV through VI...
June 5, 2024: Lasers in Medical Science
Masoud Fallahinejad Ghajari, Zahra Kiaepour, Reza Fekrazad, Serlie Hartoonian, Fatemeh Shekarchi
In pediatric dentistry, complications arising from extended soft tissue anesthesia can negatively impact patient comfort and trust in dental care. This study evaluates the clinical efficacy of diode laser-based photobiomodulation therapy (PBMT) in expediting the resolution of anesthesia in children aged 6-9 receiving inferior alveolar nerve block (IANB) injections. In this split-mouth double-blind randomized clinical trial, 36 pediatric subjects aged 6-9, requiring pulpotomy procedures on both sides of the mandible, received IANBs (single cartridge of 2% lidocaine/1:100,000 epinephrine)...
June 3, 2024: Lasers in Medical Science
Jiali Ruan, Yuxin Zheng, Suiqing Cai
Previous clinical studies have shown that pulsed dye laser (PDL) and intense pulsed light (IPL) are effective for treating erythematotelangiectatic rosacea(ETR). This article aims to compare the efficacy and safety of PDL and IPL at three different wavelength bands (broad-band, single-narrow-band, and dual-narrow-band) in treating ETR. Sixty subjects with ETR were randomly categorized into four groups and received one of the following laser treatments: PDL (595 nm), IPL with Delicate Pulse Light (DPL, 500-600 nm), IPL with M22 590 (590-1200 nm), or IPL with M22 vascular filter (530-650 nm and 900-1200 nm)...
June 1, 2024: Lasers in Medical Science
Beng Jiong Ang, Nursakinah Suardi, Muhammad Asyraf Abduraman
Photobiomodulation (PBM) holds promise as a therapy modality, but its applicability is hindered by the lack of a quantitative model to predict the optimal dose for all forms of PBM. This study investigated the optimal PBM parameters for 532 nm green laser irradiation on SHSY5Y neuroblastoma cells, a commonly used in vitro model for neurodegenerative disease studies. A two-tailed, two sample t-test with equal variance was used to obtain the p-values and statistical significance. There are 3 sets of parameters showing significant <mml:math xmlns:mml="https://www...
June 1, 2024: Lasers in Medical Science
Ana Paula do Nascimento, Giani Alves de Oliveira, João Pedro Beguetto Bressanin, Pablo Aguirra, Alex Silva Ribeiro, Lúcio Flávio Soares Caldeira, Juliano Casonatto, Cleber Ferraresi, Andreo Fernando Aguiar
Photobiomodulation therapy (PBMT) has been advocated as a potential intervention to improve muscle performance and recovery in the health and sports context. However, the short- and long-term effects of PBMT on endurance running performance remain under-researched and controversial. The purpose of this study was to investigate the acute dose-response effect of PBMT with light-emitting diodes (LEDs) on endurance performance and rating of perceived exertion (RPE; 6-20 Borg) during a 5-km running trial in recreational runners...
May 31, 2024: Lasers in Medical Science
Ahmed O El-Gendy, Sarah Ezzat, Fatma Abdel Samad, Ola Ali Dabbous, Jonathan Dahm, Michael R Hamblin, Tarek Mohamed
Enterococcus faecalis is among the most resistant bacteria found in infected root canals. The demand for cutting-edge disinfection methods has rekindled research on photoinactivation with visible light. This study investigated the bactericidal activity of femtosecond laser irradiation against vancomycin-resistant Enterococcus faecalis V583 (VRE). The effect of parameters such as wavelength and energy density on the viability and growth kinetics of VRE was studied to design an optimized laser-based antimicrobial photoinactivation approach without any prior addition of exogenous photosensitizers...
May 29, 2024: Lasers in Medical Science
Naoya Ishibashi, Takuya Nanjo, Shinichi Tao
The purpose of this study is to explore the potential application of photobiomodulation to irritable bowel syndrome. We established the following experimental groups: the Non-Stress + Sham group, which consisted of rats that were not restrained and were only subjected to sham irradiation; the Stress + Sham group, which underwent 1 hour of restraint stress followed by sham irradiation; and the Stress + Laser group, which was subjected to restraint stress and percutaneous laser irradiation bilaterally on the L6 dorsal root ganglia for 5 minutes each...
May 28, 2024: Lasers in Medical Science
Vinicius Saura Cardoso, Pedro Renan de Souza Lima da Silveira, Cristiana Maria Dos Santos, Mariana Bezerra Miranda, Ana Carolina Silva Barros, Lorena Coelho Veloso, Alessandra Tanuri Magalhães, Rebeca Barbosa da Rocha, Fuad Ahmad Hazime
PURPOSE: This study aimed to examine the impact of a 904 nm photobiomodulation (PBM) on diabetic ulcers using varying dosages. METHODS: The study was a randomized, double-blind, placebo-controlled clinical trial that compared treatments using PBM (GaAs 904 nm 30w) with three different energy densities (4 J/cm2 ; 8 J/cm2 ; 10 J/cm2 ) in the healing process of non-infected diabetic foot ulcers. Eighty volunteers (48.75% female; 58.5 ± 11...
May 28, 2024: Lasers in Medical Science
Eman Hamed, Osama Fakry Ahmed Al Balah, Mohamed Refaat, Abeer Mahmoud Badr, Ahmed Afifi
PURPOSE: Conventional approaches for enhancing wound healing may not always yield satisfactory results. Instead, we test the effectiveness of a newly developed photodynamic therapy (PDT) that uses methylene blue (MB) loaded with polyethylene glycol (PEG) (MB-PEG) hydrogel to accelerate wound healing process in mice. METHODS: A dorsal skin incision with 6 mm punch which topically subjected to MB-PEG hydrogel and a low-level laser light of red light to assess the regeneration process of wounded skin...
May 27, 2024: Lasers in Medical Science
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