Vivek Pravin Dave, Ramya Natarajan, Rajeev Reddy Pappuru
PURPOSE: To elucidate the learning curve for posterior segment diagnostic endoscopy (DE) based on the results of a self-trained (ST) and a supervised (SUP) vitreoretinal surgeon. METHODS: Retrospective review of medical records of DE performed between 2017 and 2023 by one ST and one SUP vitreoretinal surgeon at a tertiary eye care institute. Data were collected and the serial number of cases was plotted against the time taken for the procedure. A comparative regression plot was created for both the surgeons to know the slope of the learning curve...
July 10, 2024: Seminars in Ophthalmology
Muhammad M Shamim, Sam Karimaghaei, Riley Sanders, Sami H Uwaydat, Ahmed B Sallam
PURPOSE: To assess intra-operative complications and feasibility of removing crystalline lens fragments from the vitreous cavity through a limbal incision compared to a pars plana approach. DESIGN: Retrospective cohort study. SUBJECTS: 16 eyes underwent phacofragmentation via a limbal approach (Group A) and 9 eyes through a pars plana approach (Group B) at an academic center over a 10-year period. METHODS: We collected pre-operative, intra-operative, and post-operative data...
July 10, 2024: Seminars in Ophthalmology
Xueqin Zhang, Guihong Wu, Chen Qiu, Wei Yang, Tianyu Yao, Zhiru Zhang, Yue He
OBJECTIVE: To dynamically track the publications on central serous chorioretinopathy (CSC) and depict the research status and hot spots to guide future research. METHODS: Gather all papers published in this area between 2004 and 2024 in the WOSCC databases comprehensively, assess their trends, and characterize the contributions of various nations, authors, institutions, and journals. In addition, VOSviewer, CiteSpace, and R software are used to obtain the most popular keywords for the topic...
July 1, 2024: Seminars in Ophthalmology
Dalal Fatani, Adel AlSuhaibani
INTRODUCTION: Acute dacryocystitis is an acute infection and the lacrimal sac secondary to pathogenic microorganism growth within the stagnant fluid in the lacrimal sac secondary to nasolacrimal duct obstruction. METHODS: A literature review was conducted on the PubMed database using the following search terms "dacryocystic retention" and "dacryocystitis" or "dacryolith" or "lacrimal duct" or "pseudo-dacryocystitis". RESULTS: The literature review suggests that dacryocystitis in a patent nasolacrimal drainage system can stem from diverse causes including the mechanical impaction by dacryoliths, viral infections and anatomical variations...
June 24, 2024: Seminars in Ophthalmology
Andrea Gómez-Patiño, David P Piñero, Ainhoa Molina-Martín
UNLABELLED: The use of virtual reality (VR) is expected to increase exponentially in next years, and it is important to study whether VR can generate oculomotor, accommodative and binocular alterations in future users. Visual symptoms after the immersion inside VR have been widely reported, specifically in the case of simulator sickness, but the causes are still in study. Some authors have reported changes on accommodative and binocular parameters, but differences between studies made conclusions difficult...
June 20, 2024: Seminars in Ophthalmology
Naoko Wada, Seiji Takagi, Akiko Yoshikawa, Takashi Itokawa, Takahiro Maruyama, Yuichi Hori
BACKGROUND: A pallor optic nerve head (ONH) is one of the three features of retinitis pigmentosa (RP). This study aimed to assess the ONH prospectively by color tone, presence of hyper-reflective tissue, blood flow, retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC) and investigate the change in these parameters with and without ONH pallor. METHODS: The presence of ONH pallor was assessed by three independent examiners through careful examination using fundus photographs...
June 8, 2024: Seminars in Ophthalmology
Catherine Liu, Tina Wong, Dexter Leung, Hae-Young Lopilly Park, Tin Aung, Makoto Aihara, Manchima Makornwattana, Seng Kheong Fang, Ki Ho Park, Christopher Leung
PURPOSE: Topical prostaglandin analogues are commonly used to treat patients with glaucoma, but may cause periocular and periorbital complications known as prostaglandin-associated periorbitopathy syndrome (PAPS). METHODS: A literature review was conducted on PAPS. Given the lack of consensus on grading PAPS, glaucoma specialists from Asia convened to evaluate current PAPS grading systems and propose additional considerations in grading PAPS. RESULTS: Existing grading systems are limited by the lack of specificity in defining grades and consideration for patients' subjective perception of symptoms...
June 6, 2024: Seminars in Ophthalmology
Navid Sobhi, Mirsaeed Abdollahi, Ali Arman, Ata Mahmoodpoor, Ali Jafarizadeh
Methanol-induced optic neuropathy (MION) represents a critical public health issue, particularly prevalent in lower socioeconomic populations and regions with restricted alcohol access. MION, characterized by irreversible visual impairment, arises from the toxic metabolization of methanol into formaldehyde and formic acid, leading to mitochondrial oxidative phosphorylation inhibition, oxidative stress, and subsequent neurotoxicity. The pathogenesis involves axonal and glial cell degeneration within the optic nerve and potential retinal damage...
May 28, 2024: Seminars in Ophthalmology
Jens Heichel
PURPOSE: Epiphora in childhood is a frequent symptom that is typically associated with Congenital nasolacrimal duct obstruction (CNLDO). Nevertheless, inflammatory pathologies of the ocular surface as well as inside the eye, or even congenital glaucoma, must be considered in the differential diagnosis. METHODS: A comprehensive literature review concerning CNLDO was conducted. Different therapeutic steps are categorized and summarized in order to reflect the existing staged therapeutic concept...
May 24, 2024: Seminars in Ophthalmology
Mrittika Sen, Mohammad Javed Ali
No abstract text is available yet for this article.
May 24, 2024: Seminars in Ophthalmology
Nandini Bothra, Purva Agarwal, Mohammad Javed Ali
OBJECTIVE: To describe in detail the lacrimal drainage system anomalies and review of literature in patients with Goldenhar syndrome, Rubinstein-Taybi syndrome (RTS), and Ectodermal-Ectrodactyly-Clefting syndrome (EECS), their management and outcomes. METHODS: A retrospective chart review from January 2011-June 2023 of all cases presenting to the Dacryology clinic with Goldenhar syndrome, RTS, and EECS was obtained. Data collected included demographics, laterality, clinical presentations, proximal and distal lacrimal drainage anomalies, associated systemic features, management, and outcomes...
May 22, 2024: Seminars in Ophthalmology
Soham S Pal, Md Shahid Alam
Lacrimal canaliculitis is an inflammation of the proximal lacrimal drainage system. It classically presents with symptoms of redness, mucopurulent discharge, medial canthal swelling, epiphora, and pouting punctum. Despite having classical clinical characteristics it is frequently misdiagnosed. The cause can be primarily due to various infectious agents or secondary mostly due to the use of punctal plugs. There are no universally accepted guidelines for the management of canaliculitis but different medical and surgical options have been employed with varying success rates and it is notorious for recurrences and failure to therapy...
May 19, 2024: Seminars in Ophthalmology
Junjie Cai, Yamin Li, Dongdong Pan, Xiaomeng Li, Nived Moonasar, Zhong Lin, Yinghui Shi, Jianxia Lin, Peihua Zhang
PURPOSE: To evaluate the incidence and cost of intraocular lens(IOL) waste during IOL implantation, as well as the reasons for it. METHODS: A retrospective analysis was conducted on the data of 485 patients from the IOL waste registers of a single tertiary eye hospital in China during 2016-2020. The primary outcomes were the incidence, cost, and reasons for different IOL properties. Cases were examined to ascertain IOL material, design, procedural details, and causes of waste...
May 19, 2024: Seminars in Ophthalmology
Fulya Duman, Arzu Guler, Mustafa Kosker, Amir A Azari, Deniz Marangoz, Kristin M Hammersmith, Parveen K Nagra, Christopher J Rapuano
PURPOSE: To describe demographic and clinical characteristics of patients with graft failure after keratoplasty, determine the cause of graft failure and outcomes. METHODS: The charts of patients between 2008-2013 in the Cornea Service at Wills Eye Hospital with a history of a corneal transplant before the end of 2012 were retrospectively reviewed. Included were patients who had graft failure after corneal transplantation and had at least one year of follow-up after transplantation...
May 16, 2024: Seminars in Ophthalmology
James Pietris, Jessica Y Tong, Dinesh Selva
INTRODUCTION: Acute dacryocystitis is a common condition occurring secondary to nasolacrimal duct obstruction. We aim to assess the efficacy of primary dacryocystorhinostomy for the management of acute dacryocystitis. METHODS: A systematic search of the databases PubMed/MEDLINE, Embase, and CENTRAL was performed to December 2023. Data extraction and risk of bias analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
May 16, 2024: Seminars in Ophthalmology
Víctor Ponce-García, María-José Bautista-Llamas, Marta-C García-Romera
PURPOSE: This systematic review studies the relationship between Macular Pigment Optical Density (MPOD) values and cognitive and visual function in childhood. METHODS: It included cross-sectional, observational studies or controlled clinical trials in humans between 0 and 18 years of age, analyzing MPOD values in 3 main databases: PubMed, Scopus and Web of Science. The study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations...
May 8, 2024: Seminars in Ophthalmology
Vijitha S Vempuluru, Aniruddh Heroor, Prapti Praful Chheda, Gaurav Patil, Bhargavi Vatte, Swathi Kaliki
PURPOSE: To report the clinical presentation, anterior segment optical coherence tomography features, treatment, and outcomes of ocular surface squamous neoplasia (OSSN) associated with pterygium. METHODS: Retrospective interventional series of 14 cases in a 28-month study period. RESULTS: OSSN was coexistent with pterygium ( n  = 14) in < 1% of all pterygia ( n  = 7384). The mean age at the presentation of OSSN with pterygium was 49 years (median, 49 years; range, 36 to 71 years)...
May 2, 2024: Seminars in Ophthalmology
Nisar Sonam Poonam, Avriel Isaac Gudkar, Md Shahid Alam
AIM: To report a case series on canaliculocoele and to review the existing literature. METHODS AND MATERIALS: A retrospective analysis of the case records of all patients diagnosed with canaliculocoele between January 1st , 2018, and December 31st , 2019, was conducted. Only histopathologically proven cases of canaliculocoele with a minimum follow-up of 6 weeks were included. RESULTS: Five cases of canaliculocoele that presented over 2 years were included...
April 27, 2024: Seminars in Ophthalmology
Yael Lustig Barzelay, David Carmon, Mayan Dagan, Avishai Daniels, Daphna Landau-Prat, Guy J Ben Simon
PURPOSE: This study explores the relationship between acquired punctal stenosis (PS) and ocular surface disease (OSD), assessing causal mechanisms and clinical impacts, utilizing a combination of a comprehensive literature review and a detailed analysis of a patient cohort from a tertiary care center. METHODS: Data from 213 PS patients at Sheba Medical Center were retrospectively analyzed, evaluating various OSD symptoms and treatment effectiveness through standardized clinical assessments and statistical tests...
April 26, 2024: Seminars in Ophthalmology
Terence Ang, Jessica Y Tong, Sandy Patel, Valerie Juniat, Saul Rajak, Dinesh Selva
PURPOSE: To summarise the qualitative and quantitative parameters of bacterial orbital cellulitis (OC) on magnetic resonance imaging (MRI) and explore their clinical correlations. METHODS: Multi-centre retrospective study with inclusion of patients of all ages with OC who underwent MRI. Patients with isolated pre-septal cellulitis, bilateral disease and poor-quality scans were excluded. An enlargement ratio for extraocular muscles (EOMs) was calculated by dividing maximal EOM measurements from the affected side by the contralateral side...
April 25, 2024: Seminars in Ophthalmology
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