Michail Mastrogeorgiou, Elena Chatzikalil, Stamatios Theocharis, Alexandra Papoudou-Bai, Michel Péoc'h, Mousa Mobarki, Georgia Karpathiou
While several treatment choices exist for cervical cancer, such as surgical therapy, chemotherapy, and radiotherapy, some patients will still show poor prognosis. HPV infection is a principal factor for cervical cancer development, from early inflammation to proliferation, angiogenesis, and neoplastic growth. While HPV T-cell responses exist, the tumor seems to evade the immune system upon its tolerance. The latter suggests the existence of a confluent tumor microenvironment responsible for the evasion tactics employed by the neoplasm...
March 1, 2024: Histology and Histopathology