journal
https://read.qxmd.com/read/38391273/a-deep-dive-into-the-percutaneous-mitral-valve-data
#21
JOURNAL ARTICLE
Ana Paula Tagliari, Rodrigo Petersen Saadi, Gilbert H L Tang
PURPOSE OF REVIEW: This review offers insights into percutaneous mitral valve management, emphasizing pivotal trials that contributed to its evolution. RECENT FINDINGS: Mitral regurgitation (MR) is a highly prevalent heart valve disease, with surgical intervention being the gold standard for managing primary MR. However, a notable proportion of patients face ineligibility criteria or are at high surgical risk, particularly in the setting of secondary MR. To fill this gap, transcatheter therapies have emerged as less invasive alternatives...
February 26, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38386349/the-role-of-genetic-testing-in-marfan-syndrome
#22
JOURNAL ARTICLE
Emanuele Monda, Martina Caiazza, Giuseppe Limongelli
PURPOSE OF REVIEW: This review aims to delineate the genetic basis of Marfan syndrome (MFS) and underscore the pivotal role of genetic testing in the diagnosis, differential diagnosis, genotype-phenotype correlations, and overall disease management. RECENT FINDINGS: The identification of pathogenic or likely pathogenic variants in the FBN1 gene, associated with specific clinical features such as aortic root dilatation or ectopia lentis, is a major diagnostic criterion for MFS...
February 22, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38386340/metabolic-basis-of-cardiac-dysfunction-in-cancer-patients
#23
JOURNAL ARTICLE
Jane C Figueiredo, Neil Adri Bhowmick, Anja Karlstaedt
PURPOSE OF REVIEW: The relationship between metabolism and cardiovascular diseases is complex and bidirectional. Cardiac cells must adapt metabolic pathways to meet biosynthetic demands and energy requirements to maintain contractile function. During cancer, this homeostasis is challenged by the increased metabolic demands of proliferating cancer cells. RECENT FINDINGS: Tumors have a systemic metabolic impact that extends beyond the tumor microenvironment. Lipid metabolism is critical to cancer cell proliferation, metabolic adaptation, and increased cardiovascular risk...
February 22, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38386339/short-and-long-term-complications-of-hypertensive-disorders-of-pregnancy-lifelong-cardiovascular-risks-we-cannot-ignore
#24
JOURNAL ARTICLE
Cara E Saxon, Julia Bast, Josephine C Chou
PURPOSE OF REVIEW: Hypertensive disorders of pregnancy (HDP) pose a significant threat to maternal cardiovascular health, with emerging research shedding light on the enduring risks beyond the gestational period. This review highlights updates regarding cardiovascular risks associated with HDP and their implications for long-term health. RECENT FINDINGS: Patients with a history of HDP are at an elevated risk of developing chronic hypertension, ischemic heart disease, stroke, valvular heart disease, and heart failure...
February 22, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38375816/sleep-disordered-breathing-in-heart-failure
#25
JOURNAL ARTICLE
Gregory R Jackson, Justin Durland, Frank Hoyland
PURPOSE OF REVIEW: This review addresses the evolving intersection of sleep-disordered breathing (SDB) and heart failure, a topic of increasing clinical significance due to the high prevalence of SDB in heart failure patients and its impact on morbidity and mortality. It reflects recent advancements in diagnostic methodologies and therapeutic strategies. It emphasizes the need for heightened awareness among healthcare providers about the complex relationship between SDB and various forms of heart failure...
February 20, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38362936/decongestion-instead-of-ultrafiltration
#26
JOURNAL ARTICLE
Art Schuermans, Frederik H Verbrugge
PURPOSE OF REVIEW: To summarize the contemporary evidence on decongestion strategies in patients with acute heart failure (AHF). RECENT FINDINGS: While loop diuretic therapy has remained the backbone of decongestive treatment in AHF, multiple randomized clinical trials suggest that early combination with other diuretic classes or molecules with diuretic properties should be considered. Mineralocorticoid receptor antagonists and sodium-glucose co-transporter-2 inhibitors are disease-modifying drugs in heart failure that favourably influence prognosis early on, advocating their start as soon as possible in the absence of any compelling contraindications...
February 19, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38353280/intravenous-iron-in-patients-with-iron-deficiency-and-heart-failure-a-review-of-modern-evidence
#27
JOURNAL ARTICLE
Stormi E Gale, Andrew Willeford, Katherine Sandquist, Kristin Watson
PURPOSE OF REVIEW: Iron deficiency is common in patients with heart failure, affecting up to half of ambulatory patients and an even greater percentage of patients admitted for acute decompensation. Iron deficiency in this population is also associated with poor outcomes, including worse quality of life in addition to increased hospitalizations for heart failure and mortality. Evidence suggests that patients with iron deficiency in heart failure may benefit from repletion with IV iron...
February 15, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38305721/simulating-mitral-repair-lessons-learned
#28
JOURNAL ARTICLE
Abigail White, Anna Zarzycki, Gianluigi Bisleri
PURPOSE OF REVIEW: With the growing complexity of cardiac surgical cases, increased focus on patient safety, and minimally invasive techniques, simulation-based training has experienced a renaissance. This review highlights important elements of simulation-based training, focusing specifically on available simulators for mitral valve repair and the uses for simulation. RECENT FINDINGS: Referring to simulators as being high or low fidelity is oversimplified. Fidelity is a multifactorial concept, and for surgical task trainers, structural and functional fidelity should be discussed...
February 3, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38294187/beyond-weight-loss-the-emerging-role-of-incretin-based-treatments-in-cardiometabolic-hfpef
#29
JOURNAL ARTICLE
Federico Capone, Natasha Nambiar, Gabriele G Schiattarella
PURPOSE OF REVIEW: Incretin-based drugs are potent weight-lowering agents, emerging as potential breakthrough therapy for the treatment of obesity-related phenotype of heart failure with preserved ejection fraction (HFpEF). In this review article, we will discuss the contribution of weight loss as part of the benefits of incretin-based medications in obese patients with HFpEF. Furthermore, we will describe the potential effects of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists on the heart, particularly in relation to HFpEF pathophysiology...
January 31, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38567949/integration-of-palliative-care-across-the-spectrum-of-heart-failure-care-and-therapies-considerations-contemporary-data-and-challenges
#30
REVIEW
Sarah Chuzi, Katharine Manning
PURPOSE OF REVIEW: Heart failure (HF) is characterized by significant symptoms, compromised quality of life, frequent hospital admissions, and high mortality, and is therefore well suited to palliative care (PC) intervention. This review elaborates the current PC needs of patients with HF across the spectrum of disease, including patients who undergo advanced HF surgical therapies, and reviews the current data and future directions for PC integration in HF care. RECENT FINDINGS: Patients with chronic HF, as well as those who are being evaluated for or who have undergone advanced HF surgical therapies such as left ventricular assist device or heart transplantation, have a number of PC needs, including decision-making, symptoms and quality of life, caregiver support, and end-of-life care...
May 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38567948/implementation-of-remote-monitoring-strategies-to-improve-chronic-heart-failure-management
#31
REVIEW
Vinh Q Chau, Teruhiko Imamura, Nikhil Narang
PURPOSE OF REVIEW: The goal of this review is to describe the current evidence available for remote monitoring devices available for patients with chronic heart failure, and also detail practical clinical recommendations for implementing these tools in daily clinical practice. RECENT FINDINGS: Several devices ranging from sophisticated multiparametric algorithms in defibrillators, implantable pulmonary artery pressure sensors, and wearable devices to measure thoracic impedance can be utilized as important adjunctive tools to reduce the risk of heart failure hospitalization in patients with chronic heart failure...
May 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38567947/editorial-gene-based-renaming-of-human-diseases
#32
JOURNAL ARTICLE
Ali J Marian
No abstract text is available yet for this article.
May 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38294186/obesity-cardiometabolic-phenotype-of-heart-failure-with-preserved-ejection-fraction-mechanisms-to-recent-trials
#33
REVIEW
Raj Verma, Nitish K Dhingra, Kim A Connelly
PURPOSE OF REVIEW: Heart failure with preserved ejection fraction (HFpEF) is a leading and growing cause of morbidity and mortality globally. Of the various phenotypes identified, the obesity (or cardiometabolic) phenotype appears to be most common. The purpose of this review is to provide the clinician with an abridged understanding of recent developments that have elucidated obesity/visceral adiposity as a central mechanism linking inflammation/immune dysregulation to the development of the HFpEF syndrome...
March 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38170194/a-review-of-the-contemporary-use-of-inotropes-in-patients-with-heart-failure
#34
REVIEW
Radhika Neicheril, David Snipelisky
PURPOSE OF REVIEW: The role of inotropes has evolved with its use now expanding over multiple indications including cardiogenic shock, low cardiac output states, bridging therapy to transplant or mechanical support, and palliative care. There remains no consensus as to the recommended inotrope for the failing heart. We aim to provide an overview of the recent literature related to inotrope therapy and its application in patients with advanced heart failure and hemodynamic compromise. RECENT FINDINGS: In this review, we outline various clinical scenarios that warrant the use of inotrope therapy and the associated recommendations...
March 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38116833/heart-transplant-donation-after-circulatory-death-current-status-and-implications
#35
REVIEW
Savitri Fedson
PURPOSE OF REVIEW: The use of cardiac transplantation following circulatory death (DCD) has been limited worldwide. Concerns about cardiac function after warm ischemia and the potential for decreased graft function have been important considerations in this hesitancy. In addition, ethical and legal questions about the two widely used organ procurement methods have led to discussions and public education in many countries. RECENT FINDINGS: Publication of a US randomized trial of cardiac transplantation following DCD has shown that it is both feasible and has similar short-term outcomes compared with cardiac transplantation following brain death (DBD)...
March 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38078601/salt-restriction-for-treatment-of-hypertension-current-state-and-future-directions
#36
REVIEW
Philip Nolan, John W McEvoy
PURPOSE OF REVIEW: Given the adverse effects of excess dietary sodium chloride (also known as table salt) on blood pressure (BP) and cardiovascular disease (CVD), restriction of dietary sodium is recommended by numerous guidelines. The strictest of these recommend no more than 1.5 g/day of dietary sodium among hypertensive persons. However, average dietary sodium intake in the population is closer to 5 g/day and there is debate about whether too much sodium restriction may be associated with increased CVD risk...
January 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/38078600/measuring-lipoprotein-a-for-cardiovascular-disease-prevention-in-whom-and-when
#37
REVIEW
Peter E Thomas, Signe Vedel-Krogh, Børge G Nordestgaard
PURPOSE OF REVIEW: The aim of this study is to summarize major cardiovascular guideline recommendations on lipoprotein(a) and highlighting recent findings that emphasize how measuring lipoprotein(a) once in all adults is meaningful regardless of age, sex, comorbidities, or ethnicity. RECENT FINDINGS: Many international guidelines now recommend once in a lifetime measurement of lipoprotein(a) in all adult individuals to facilitate accurate risk prediction. Lipoprotein(a)-lowering therapy to reduce cardiovascular disease is on the horizon, with results from the first phase 3 trial expected in 2025...
January 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/37934715/2023-update-on-equity-diversity-and-inclusion-in-canadian-cardiac-surgery
#38
REVIEW
Lina A Elfaki, Rosalind Groenewoud, Akachukwu Nwakoby, Areeba Zubair, Raj Verma, Bobby Yanagawa
PURPOSE OF REVIEW: Despite efforts to diversify the medical field, cardiac surgery remains amongst the least diverse specialties. Specifically, the percentage of women and racial minorities has remained low in past few decades. This may impact prospective trainee recruitment and surgical care. This paper highlights recent efforts that aim to promote diversity and inclusion of the Canadian cardiac surgical workforce. RECENT FINDINGS: Formal programs have been established to support students at different stages of training...
January 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/37921758/cardiovascular-disease-prevention-in-women-the-current-state-in-2023
#39
REVIEW
Aarti Purohit, Yoo Jin Kim, Erin D Michos
PURPOSE OF REVIEW: Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality for women globally. The purpose of this review is to provide an updated overview of CVD prevention in women, focusing on what is currently understood about female-specific or female-predominant CVD risk factors and the importance of tailored strategies for risk assessment and medical interventions. RECENT FINDINGS: Recent studies have demonstrated the need to account for risk factors specific to women in current risk assessment models for CVD, including early menarche, polycystic ovary syndrome, adverse pregnancy outcomes, early menopause, and chronic inflammatory conditions...
January 1, 2024: Current Opinion in Cardiology
https://read.qxmd.com/read/37751365/advances-in-cardiac-pacing-with-leadless-pacemakers-and-conduction-system-pacing
#40
REVIEW
Sulaiman Somani, Albert J Rogers
PURPOSE OF REVIEW: The field of cardiac pacing has undergone significant evolution with the introduction and adoption of conduction system pacing (CSP) and leadless pacemakers (LLPMs). These innovations provide benefits over conventional pacing methods including avoiding lead related complications and achieving more physiological cardiac activation. This review critically assesses the latest advancements in CSP and LLPMs, including their benefits, challenges, and potential for future growth...
January 1, 2024: Current Opinion in Cardiology
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