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Journal of Gastroenterology and Hepatology | Page 5

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https://read.qxmd.com/read/31711259/prevalence-of-prothrombotic-factors-in-patients-with-budd-chiari-syndrome-or-noncirrhotic-nonmalignant-portal-vein-thrombosis-a-hospital-based-observational-study
#81
Jiahao Fan, Qiuhe Wang, Bohan Luo, Hui Chen, Zhengyu Wang, Jing Niu, Jie Yuan, Xulong Yuan, Wei Bai, Chuangye He, Wengang Guo, Kai Li, Zhanxin Yin, Daiming Fan, Guohong Han
Background and Aims Comprehensive investigations on the prothrombotic factors of splanchnic vein thrombosis (SVT), including Budd-Chiari syndrome (BCS) and noncirrhotic nonmalignant portal vein thrombosis (PVT), in Eastern patients are scarce. METHODS: Between March 2012 and July 2017, 812 consecutive patients, including 418 BCS and 394 noncirrhotic nonmalignant PVT patients, were admitted to Xijing Hospital (a Chinese tertiary academic hospital) and screened for prothrombotic factors...
November 11, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31698521/hepatocellular-adenoma-in-taiwan-distinct-ensemble-of-male-predominance-overweight-obesity-and-inflammatory-subtype
#82
Wen-Chih Huang, Jau-Yu Liau, Yung-Ming Jeng, Kao-Lang Liu, Chia-Nan Lin, Hsiang-Lin Song, Jia-Huei Tsai
BACKGROUND AND AIM: The clinicopathologic features of hepatocellular adenoma in Asian populations have been poorly defined. The study aimed to characterize this rare entity in a single institution in Taiwan. METHODS: In total, 45 hepatocellular adenomas from 1995 to 2018 were included and sent for pathologic review and molecular subtyping. RESULTS: The numbers of patients with hepatocellular adenoma has doubled in the recent decade. Surprisingly, men outnumbered women in our cohort (n = 26, 58% vs N = 19, 42%)...
November 7, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31698517/gastrointestinal-anterior-mediastinal-colonic-interposition-on-f-18-fdg-pet-ct-imaging
#83
REVIEW
K N Huynh, B D Nguyen
No abstract text is available yet for this article.
November 7, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31696975/efficacy-of-adjuvant-curcumin-therapy-in-ulcerative-colitis-a-meta-analysis-of-randomized-controlled-trials
#84
Ting Zheng, Xin Wang, Zongran Chen, Anqi He, Zicheng Zheng, Gang Liu
BACKGROUND AND AIM: Aminosalicylic acids are recognized to be the first-line treatment options for ulcerative colitis. Currently, the effectiveness of curcumin as an adjuvant treatment in ulcerative colitis has been investigated, which was still controversial. This study aimed to systematically review and meta-analyze the efficacy and safety of curcumin as an adjuvant treatment in ulcerative colitis. METHODS: The PubMed, EMBASE, and Cochrane Library databases were searched from original to July 2019, and relevant randomized controlled clinical trials were enrolled and analyzed...
November 7, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31694062/gastrointestinal-lymphoblastic-lymphoma-presenting-as-huge-abdominal-masses
#85
REVIEW
Y Nam, K Nam, N-H Myung, M Jeon, J Kim
No abstract text is available yet for this article.
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31693767/effect-of-preventive-closure-of-the-frenulum-after-endoscopic-papillectomy-a-prospective-pilot-study
#86
Koichi Kagawa, Kensuke Kubota, Yusuke Kurita, Yuri Takagi, Ken Ishii, Sho Hasegawa, Akito Iwasaki, Takamitsu Sato, Yuji Fujita, Shingo Kato, Seitaro Watanabe, Yusuke Sekino, Kunihiro Hosono, Atsushi Nakajima
BACKGROUND AND AIMS: The usefulness of preventive closure of the frenulum after endoscopic papillectomy (EP) could reduce bleeding. The feasibility and safety of clipping was evaluated in this prospective pilot study. METHODS: This study involved 40 consecutive patients who underwent preventive closure of the frenulum by clipping just after EP. The outcome data were compared with those of the previous 40 patients in whom no preemptive closure had been performed (no-closure group) (UMIN000014783)...
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31693762/do-we-still-need-a-diverticuloscope-for-the-flexible-endoscopic-septotomy-of-zenker-s-diverticulum
#87
Clément Bresteau, Maximilien Barret, Marie-Anne Guillaumot, Einas Abou Ali, Arthur Belle, Sarah Leblanc, Ammar Oudjit, Anthony Dohan, Romain Coriat, Stanislas Chaussade
BACKGROUND AND AIM: Zenker's diverticulum (ZD) is the most common type of diverticulum in the esophagus. The endoscopic septotomy of the diverticular wall has become a widely accepted treatment modality, but the recurrence rate is unclear. Our aim was to assess short-term and long-term success rates after flexible endoscopic septotomy for the treatment of ZD. METHODS: All consecutive patients treated at our department for a ZD between November 2014 and September 2018 were included...
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31693755/increasing-prevalence-of-primary-biliary-cholangitis-in-victoria-australia
#88
Janine French, Ingrid van der Mei, Steve Simpson, Justin Ng, Peter Angus, John Lubel, Amanda Nicoll, Siddharth Sood, Stuart K Roberts, William Kemp, Niranjan Arachchi, Anouk Dev, Alexander Thompson, Paul J Gow
BACKGROUND AND AIM: The prevalence of primary biliary cholangitis (PBC) reported in different countries varies significantly and in some parts of the world appears to be increasing. The aim of this study was to determine the 2013 prevalence of PBC in Victoria, Australia, and to determine the time trend by comparing it to previous studies undertaken in 1991 and 2002. METHODS: Four case-finding methods were used to identify cases of PBC in Victoria. 1. Physicians' survey; 2...
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31693241/gastrointestinal-burkitt-lymphoma-showing-multiple-tumorous-lesions-in-the-gastrointestinal-tract
#89
REVIEW
A Harada, T Torisu, M Esaki
No abstract text is available yet for this article.
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31692119/can-transanal-natural-orifice-specimen-extraction-after-laparoscopic-anterior-resection-for-colorectal-cancer-reduce-the-inflammatory-response
#90
Sicheng Zhou, Xuewei Wang, Chuanduo Zhao, Haitao Zhou, Wei Pei, Jianwei Liang, Zhixiang Zhou, Xishan Wang
BACKGROUND: Avoiding abdominal incisions is one of the unique features of natural orifice specimen extraction (NOSE) surgery. There has been no consensus on whether the avoidance of abdominal incisions can reduce the systemic inflammatory response after NOSE surgery. This study was designed to evaluate the safety and feasibility of transanal NOSE, especially the inflammatory response after transanal NOSE versus mini-laparotomy (LAP). METHOD: A total of 172 colorectal cancer patients who underwent transanal NOSE were matched with 172 patients who underwent LAP for colorectal cancer...
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31692099/idiopathic-pneumatosis-intestinalis-secondary-to-lactulose-use-in-patients-with-cirrhosis
#91
Lee J Varelas, Matthew J Klinge, Shahid M Malik, Amir A Borhani, Matthew Neal
BACKGROUND & AIMS: Few case reports exist that link lactulose use with pneumatosis intestinalis in cirrhotics. This study investigates the relationship between lactulose use and idiopathic pneumatosis intestinalis in a cohort of cirrhotic patients. METHODS: This case series considers several notable cases of patients with idiopathic pneumatosis intestinalis and concurrent lactulose use. Idiopathic pneumatosis intestinalis was defined as pneumatosis intestinalis with no identifiable etiology...
November 6, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31689724/coagulation-abnormalities-bleeding-thrombosis-and-management-of-patients-with-acute-liver-failure-in-australia-and-new-zealand
#92
Stephen Warrillow, Caleb Fisher, Heath Tibballs, Michael Bailey, Colin McArthur, Pia Lawson-Smith, Bheemasenachar Prasad, Matthew Anstey, Bala Venkatesh, Gemma Dashwood, James Walsham, Andrew Holt, Ubbo Wiersema, David Gattas, Matthew Zoeller, Mercedes Garcia Alvarez, Rinaldo Bellomo
BACKGROUND AND AIM: To study the management of coagulation and hematological derangements among severe acute liver failure (ALF) patients in Australia and New Zealand liver transplant intensive care units (ICUs). METHODS: Analysis of key baseline characteristics, etiology, coagulation and hematological tests, use of blood products, thrombotic complications, and clinical outcomes during the first ICU week. RESULTS: We studied 62 ALF patients...
November 5, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31682026/low-dose-and-same-day-use-of-polyethylene-glycol-improves-image-of-video-capsule-endoscopy-a-multi-center-randomized-clinical-trial
#93
Shan Wu, Liang Zhong, Ping Zheng, Yu-Gang Wang, Wei-Qun Ding, Qi Yu, Ping-Ping Hui, Hui-Min Chen, Yun-Jie Gao, Zhi-Zheng Ge
BACKGROUND AND AIM: Clear visualization of the small bowel is a requirement for satisfactory video capsule endoscopy (VCE). The aim of this study was to identify the optimal dose and timing of polyethylene-glycol (PEG) for small-bowel preparation before VCE. METHODS: 410 patients were enrolled in this prospective randomized trial. All patients fasted for 12 h and ingested 320 mg simethicone 30 min before swallowing the capsule. Patients were randomized into 5 groups: Group A (no PEG), Group B (1 L PEG, 12 h before VCE), Group C (2 L PEG, 12 h before VCE), Group D (1 L PEG, 4 h before VCE), and Group E (2 L PEG, 4 h before VCE)...
November 4, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677201/long-term-outcome-of-eus-guided-pancreatic-duct-drainage-using-a-fully-covered-self-expandable-metal-stent-for-pancreaticojejunal-anastomosis-stricture
#94
Dongwook Oh, Do Hyun Park, Tae Jun Song, Sang Soo Lee, Dong-Wan Seo, Sung Koo Lee, Myung-Hwan Kim
BACKGROUND AND AIM: EUS-guided pancreatic duct drainage (EUS-PD) has been proposed for pancreatic duct obstruction after failure of endoscopic retrograde pancreatography (ERP). We evaluate the long-term outcomes of EUS-PD using a fully covered self-expandable metal stent (FCSEMS) for pancreaticojejunal anastomosis (PJA) strictures following Whipple procedures. METHODS: Twenty-three patients with PJA strictures underwent EUS-PD according to the findings of EUS-guided pancreatogram and the passage of the guidewire through PJA stricture (complete vs...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677195/effect-of-pnpla3-polymorphism-on-diagnostic-performance-of-various-non-invasive-markers-for-diagnosing-and-staging-nafld
#95
Wen-Yue Liu, Kenneth I Zheng, Xiao-Yan Pan, Hong-Lei Ma, Pei-Wu Zhu, Xi-Xi Wu, Rafael S Rios, Giovanni Targher, Christopher D Byrne, Xiao-Dong Wang, Yong-Ping Chen, Ming-Hua Zheng
BACKGROUND AND AIM: Patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M (rs738409) genotype influences clinical/biochemical characteristics in patients with nonalcoholic fatty liver disease (NAFLD), but whether PNPLA3-I148M (rs738409) genotype also influences the diagnostic performance of non-invasive diagnostic tests for NAFLD is uncertain. Our aim was to investigate the differences in diagnostic performance of non-invasive diagnostic tests for NAFLD according to PNPLA3-I148M (rs738409) genotype...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677186/long-term-results-of-variceal-bleeding-management-in-302-patients-with-chronic-extrahepatic-portal-vein-obstruction
#96
Hui Chen, Chuangye He, Yong Lv, Jiahao Fan, Shihao Tang, Jing Niu, Jie Yuan, Bohan Luo, Wengang Guo, Zhanxin Yin, Guohong Han
BACKGROUND AND AIM: Treatment modalities of variceal bleeding or rebleeding for extrahepatic portal vein obstruction (EHPVO) are limited and their long-term results and prognostic factors are unclear. This study aimed at assessing the long-term results of EHPVO treated with current recommendations and investigating the influencing factors. METHODS: Between 2009 and 2016, 302 consecutive patients with EHPVO were included. Watch-and-wait policy was applied for those with no (n=59) or small varices (n=55), nonselective beta-adrenergic blocker (NSBB) and NSBB plus endotherapy were for primary (n=115) and secondary prophylaxis (n=87), transjugular intrahepatic portosystemic shunt (TIPS) or combination therapy was for those with recurrent bleeding (n=92)...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677185/igm-response-is-a-prognostic-biomarker-of-primary-biliary-cholangitis-treated-with-ursodeoxycholic-acid-and-bezafibrate
#97
Keiko Takano, Chisato Saeki, Tsunekazu Oikawa, Akihisa Hidaka, Yusuke Mizuno, Jinya Ishida, Kazuki Takakura, Masanori Nakano, Yuichi Torisu, Katsushi Amano, Tomohisa Ishikawa, Mikio Zeniya, Akihito Tsubota, Masayuki Saruta
AIM: Primary biliary cholangitis (PBC) patients who are refractory to ursodeoxycholic acid (UDCA) are at risk for progression to cirrhosis and liver failure. Bezafibrate could be an alternative second-line therapeutic option in these patients. This study aimed to evaluate the long-term outcome(s) of combined UDCA and bezafibrate therapy in UDCA-refractory PBC patients and identify prognostic factors. METHODS: Among 445 patients treated with UDCA, 150 patients inadequately responded to UDCA monotherapy and received long-term UDCA plus bezafibrate (median, 15 years)...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677184/planning-mass-eradication-of-helicobacter-pylori-infection-for-indigenous-taiwanese-peoples-to-reduce-gastric-cancer
#98
Ming-Jong Bair, Shu-Lin Chuang, Wei-Yi Lei, Chien-Lin Chen, Hui-Wen Tian, Tsung-Hsien Chiang, William Wang-Yu Su, Chiu-Chu Lin, Yuan-Ting Chung Lo, Yann-Yuh Jou, Chien-Yuan Wu, Shu-Li Chia, Ming-Shiang Wu, Hsiu-Hsi Chen, Chia-Hsiang Chu, Yi-Chia Lee, Ying-Wei Wang
BACKGROUND AND AIM: To identify gastric cancer burden in Indigenous Taiwanese peoples and conduct a project to evaluate how to reduce the disparities most effectively in Indigenous communities. METHODS: First, we quantified the health disparities in gastric cancer in Indigenous peoples using data from the cancer registries during the period of 2006-2014. Second, we identified parameters that might be associated with Helicobacter pylori infection or help identify a good eradication strategy...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31677183/effectiveness-of-risk-scoring-systems-in-predicting-endoscopic-treatment-in-colonic-diverticular-bleeding
#99
Noriaki Oguri, Takashi Ikeya, Daiki Kobayashi, Kazuki Yamamoto, Takaaki Yoshimoto, Ayaka Takasu, Takeshi Okamoto, Yasutoshi Shiratori, Shuhei Okuyama, Koichi Takagi, Kenji Nakamura, Katsuyuki Fukuda
BACKGROUND/AIMS: The identification of Stigmata of recent hemorrhage (SRH) in colonic diverticular bleeding (CDB) enables an endoscopic treatment, and can improve the clinical outcome. However SRH identification rate remains low. To investigate whether NOBLADS and Strate scoring systems are useful for predicting SRH identification rate of CDB pre-procedurally via colonoscopy. METHODS: In this single-center retrospective observational study, 302 patients who experienced their first episode of CDB from April 2008 to March 2018 were included...
November 1, 2019: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/31674688/the-role-of-antibiotics-in-upper-gastrointestinal-bleeding-among-cirrhotic-patients-without-major-complications-after-endoscopic-hemostasis
#100
Cheng-Kun Wu, Shih-Cheng Yang, Chih-Ming Liang, Yu-Chi Li, Wen-Shuo Yeh, Wei-Chen Tai, Chen-Hsiang Lee, Yao-Hsu Yang, Chien-Ning Hsu, Tzu-Hsien Tsai, Seng-Kee Chuah
BACKGROUND AND AIM: Antibiotic prophylaxis should be instituted for cirrhotic patients with upper gastrointestinal bleeding (UGIB), but the benefit on compensated patients remains undetermined. We aimed to compare the clinical outcomes between cirrhotic patients without major complications with UGIB with and without antibiotic prophylaxis. METHODS: We conducted this population-based cohort study by using Taiwanese Longitudinal Health Insurance Database 2000 (LHID2000, between 1997 to 2013), aged 18 years or older with a hospital discharge diagnosis of cirrhosis (n = 64,506), UGIB (n = 7,784), and endoscopic therapy (n = 2,292)...
November 1, 2019: Journal of Gastroenterology and Hepatology
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