journal
https://read.qxmd.com/read/38751200/individualized-care-delivery-for-children-with-autism-and-related-disabilities-undergoing-overnight-video-electroencephalography-eeg-one-hospital-s-experience-with-a-coordinated-team-approach
#1
JOURNAL ARTICLE
Kalyn Nix, Atara Siegel, Jessica V Smith, Elizabeth M Wells, Kathleen Atmore
Background and Purpose: Children with developmental disabilities have increased risk of epilepsy and need for overnight video electroencephalographic (EEG) monitoring. However, video EEGs have historically been considered difficult to complete for this population. An autism support service at a pediatric tertiary care hospital implemented a coordinated team approach to help children with developmental disability tolerate overnight video EEGs. The project included completion of a caregiver-report preprocedure questionnaire that then was shared with the multidisciplinary team and used to create individualized care plans...
May 15, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38751192/abnormality-of-early-white-matter-development-in-tuberous-sclerosis-complex-and-autism-spectrum-disorder-longitudinal-analysis-of-diffusion-tensor-imaging-measures
#2
JOURNAL ARTICLE
Siddharth Srivastava, Fanghan Yang, Anna K Prohl, Peter E Davis, Jamie K Capal, Rajna Filip-Dhima, E Martina Bebin, Darcy A Krueger, Hope Northrup, Joyce Y Wu, Simon K Warfield, Mustafa Sahin, Bo Zhang
Background: Abnormalities in white matter development may influence development of autism spectrum disorder in tuberous sclerosis complex (TSC). Our goals for this study were as follows: (1) use data from a longitudinal neuroimaging study of tuberous sclerosis complex (TACERN) to develop optimized linear mixed effects models for analyzing longitudinal, repeated diffusion tensor imaging metrics (fractional anisotropy, mean diffusivity) pertaining to select white matter tracts, in relation to positive Autism Diagnostic Observation Schedule-Second Edition classification at 36 months, and (2) perform an exploratory analysis using optimized models applied to all white matter tracts from these data...
May 15, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38751188/proceedings-of-the-47th-annual-southern-pediatric-neurology-society-meeting-new-orleans-la-march-23-2024
#3
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
May 15, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38748539/headache-and-other-factors-modifying-cerebrospinal-fluid-opening-pressure-in-pediatric-patients
#4
JOURNAL ARTICLE
Oscar M Espitia Segura, Ana M Bedoya Morales, Cristina L Ramírez-Sierra, Juan D Farfán-Albarracín, Sofy H Pérez Cárdenas, Juan D Sánchez Rincón, Jennifer J Guzmán-Porras, Luisa F López Mora, Mateo H Ramírez Salazar, Leydi A Ceballos Inga, María C Rueda Rodríguez, Hugo A Téllez Prada, Juan C Castro Rubio, Ingrid Lemus Espitia, Juan D Guevara Ramos
Cerebrospinal fluid opening pressure values are associated with various neurologic diseases; however, numerous factors can modify this measurement. This study aims to describe factors related to modifications in opening pressure measurements in pediatric patients. Methods: A retrospective analysis of lumbar punctures in pediatric patients conducted by the neuropediatrics group with institutional standardization. Bivariate and linear regression analyses were performed to determine the association between opening pressure and variables included in the study...
May 15, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38698642/has-the-incidence-of-febrile-convulsions-in-childhood-changed-during-the-sars-cov-2-pandemic
#5
JOURNAL ARTICLE
Monika Kovacs, Lilla Makszin, Zoltan Nyul, Katalin Hollody
Introduction: SARS-CoV-2 infection in children is usually asymptomatic or only mild symptoms are typical. The aim of our study was to assess the incidence of febrile convulsions in our own patients with COVID-19. Patients and Methods: In our retrospective study, we reviewed the data of children who presented at our University Hospital from March 2020 to March 2022 with febrile convulsion. The control group were children admitted to the hospital because of febrile convulsions from January 2018 to January 2020...
May 2, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38659405/development-of-an-infantile-gm2-clinical-rating-scale-remote-assessment-of-clinically-meaningful-health-related-function
#6
JOURNAL ARTICLE
Michael Kiefer, Meg Simione, Florian S Eichler, Elise L Townsend
GM2 gangliosidoses (GM2) are a group of rare lysosomal storage disorders in which accumulation of GM2 gangliosides results in progressive central nervous system damage. The infantile GM2 phenotype is characterized by delays in milestones by 6 months of age, followed by rapid loss of motor, cognitive, and visual function. Advancements in early diagnosis and pharmacotherapies provide promise for improved outcomes. However, the lack of feasible and clinically meaningful clinical outcome assessments for GM2 poses a challenge to characterizing GM2 natural history and selecting clinical trial endpoints...
April 25, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38629166/recognition-and-management-of-delirium-in-the-neonatal-intensive-care-unit-case-series-from-a-single-center-level-iv-intensive-care-unit
#7
JOURNAL ARTICLE
Stacey Dornette, Stephen Deptola, Brianna Hemmann, Charu Venkatesan, DonnaMaria E Cortezzo
Delirium often goes unrecognized in neonates and children because of lack of experience in evaluating behavior and cognition, insufficient awareness of the prevalence, and nondistinctive symptoms in this population. Although there are increasing reports of the presence of delirium in neonates, there are little data to guide the pharmacologic treatment in this population. In this retrospective single-center case series, we present our experience using quetiapine to treat delirium in 9 medically complex neonates...
April 17, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38544431/brain-volumes-in-opsoclonus-myoclonus-ataxia-syndrome-a-longitudinal-study
#8
JOURNAL ARTICLE
Montaha Almudhry, Matthias W Wagner, Giulia Longoni, Carmen Yea, Logi Vidarsson, Birgit Ertl-Wagner, E Ann Yeh
INTRODUCTION: Little is known about the longitudinal trajectory of brain growth in children with opsoclonus-myoclonus ataxia syndrome. We performed a longitudinal evaluation of brain volumes in pediatric opsoclonus-myoclonus ataxia syndrome patients compared with age- and sex-matched healthy children. PATIENTS AND METHODS: This longitudinal case-control study included brain magnetic resonance imaging (MRI) scans from consecutive pediatric opsoclonus-myoclonus ataxia syndrome patients (2009-2020) and age- and sex-matched healthy control children...
March 27, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38532733/characterization-of-fine-motor-and-visual-motor-skills-in-aicardi-gouti%C3%A3-res-syndrome
#9
JOURNAL ARTICLE
Stacy V Cusack, Francesco Gavazzi, Isabella Peixoto de Barcelos, Nicholson B Modesti, Sarah Woidill, Brielle Formanowski, Sara B DeMauro, Scott Lorch, Ariel Vincent, Abbas F Jawad, Timothy Estilow, Allan M Glanzman, Adeline Vanderver, Laura A Adang
Aicardi-Goutières syndrome is a genetic inflammatory disorder resulting in dispersed neurologic dysfunction. Despite a recognition of overall motor impairment, fine and visual motor skills are undercharacterized. We hypothesize that there is a spectrum of fine and visual motor skills in the Aicardi-Goutières syndrome population as captured by a standard outcome measure, the Peabody Developmental Motor Scales (PDMS-2), which will be proportional to overall disease severity.In a cohort of 74 subjects, the Peabody Developmental Motor Scales-2 grasping and visual-motor integration subtests were administered concurrently with the Aicardi-Goutières syndrome Severity Scale (severe [range 0-3], moderate [range 4-8], and attenuated [range 9-11])...
March 27, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38528770/yield-and-utility-of-routine-epilepsy-panel-genetic-testing-among-young-patients-with-seizures
#10
JOURNAL ARTICLE
Emily Grew, Mayuri Reddy, Hayley Reichner, Jinsoo Kim, Misbah Salam, Anjum Hashim
Objective: We examined the yield of routine epilepsy panel genetic testing in pediatric patients. Methods: We retrospectively reviewed epilepsy genetic panel results routinely performed in the hospital or clinic on patients <8 years old from July 2021 to July 2023. We evaluated demographics, family history, seizure type, severity, and frequency, development, tone and movement abnormalities, dysmorphism, and electroencephalography (EEG) or magnetic resonance imaging (MRI) results as predictors of results...
March 25, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38528756/in-support-of-single-payer-health-care
#11
EDITORIAL
Jay Desai, Kiarash Sadrieh
No abstract text is available yet for this article.
March 25, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38504646/new-onset-vision-impairment-in-children-magnetic-resonance-imaging-findings-by-age-groups
#12
JOURNAL ARTICLE
Esra Çıvgın, Semra Duran, Izzet Selçuk Parlak, Başak Gülleroğlu, İnci Elif Erbahçeci Timur, Özge Dedeoğlu, Ayşe Seçil Yücel Ekşioğlu
INTRODUCTION: Non-traumatic visual impairment is rare in the pediatric population, but early diagnosis and treatment of the cause is crucial to prevent long-term consequences affecting children's neurocognitive development. The authors aim to determine the most common causes of non-traumatic visual impairment in pediatric patients according to age groups by magnetic resonance imaging (MRI). METHODS: Images of patients who underwent contrast-enhanced cranial and orbital MRI for new-onset visual impairment between June 2019 and June 2022 were retrospectively reviewed...
March 20, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38500008/clearance-for-driving-in-genetic-generalized-epilepsy
#13
JOURNAL ARTICLE
Jay Desai, Kiarash Sadrieh, Eesha Singh
A key aspect of management of genetic generalized epilepsy involves assessing seizure control and deciding suitability for driving motor vehicles. We surveyed child neurologists and pediatric epileptologists on key questions that practitioners should ask prior to providing clearance for driving. The results showed a wide variability of practice among responders. We propose a likely appropriate process necessary to determine seizure control.
March 18, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38488459/rare-cases-of-pseudomonas-aeruginosa-meningitis-in-children-10-year-experience-in-a-single-center
#14
JOURNAL ARTICLE
Lijun Liu, Lvchang Zhu, Chanchan Hu, Shuzhen Zhu, Sheng Ye
OBJECTIVE: The primary objective was to elucidate the epidemiologic characteristics, risk determinants, and clinical outcomes associated with Pseudomonas aeruginosa -induced meningitis. METHODS: All cases of meningitis caused by Pseudomonas aeruginosa that were treated at the hospital between 2012 and 2022 were retrospectively analyzed and detailed. RESULTS: During a 10-year period, only 10 patients satisfied the inclusion criteria. Three patients had previously undergone neurosurgical procedures and 4 patients had leukemia...
March 15, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38477320/pediatric-subacute-sclerosing-panencephalitis-a-narrative-review-on-measles-and-the-future-of-vaccination
#15
REVIEW
Samia Aziz Sulaiman, Nilofar M Vora, Kusumita Chhabra, Muhammad Arsalan Bashir, Zainab Awan
Subacute sclerosing panencephalitis is a rare complication due to persistent measles infection, characterized by cognitive and motor deterioration. Because subacute sclerosing panencephalitis is considered a potentially fatal complication of measles and usually presents in young populations, particularly those with measles infection under the age of 2 years, new approaches to implement vaccination programs must be devised to help avoid the worsening of patient outcome. Until the disease is eradicated globally, children in all regions of the world remain at risk of measles infection and its respective complications, and therefore, the vaccine is considered the optimal preventative measure...
March 13, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38419482/opening-pressure-and-post-lumbar-puncture-headache-in-children-undergoing-intrathecal-baclofen-trial
#16
JOURNAL ARTICLE
Amanda E Summers, Jenny L Wilson
Aims: Post-lumbar puncture headache occurs in 5% to 12% of children. The purpose of this study was to determine the frequency and predictors of post-lumbar puncture headache in children with hypertonia undergoing lumbar puncture for intrathecal baclofen trial. Methods: This was a retrospective single-center review of all 43 children (<18 years) with hypertonia and/or dyskinesia undergoing intrathecal baclofen trial from 2013-2022. Predictors of post-lumbar puncture headache were evaluated via 2-way paired t test and Fisher exact test...
February 28, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38409793/stereotactic-awake-basal-ganglia-electrophysiological-recording-and-stimulation-sabers-a-novel-staged-procedure-for-personalized-targeting-of-deep-brain-stimulation-in-pediatric-movement-and-neuropsychiatric-disorders
#17
JOURNAL ARTICLE
Mark A Liker, Terence D Sanger, Jennifer A MacLean, Jaya Nataraj, Enrique Arguelles, Mark Krieger, Aaron Robison, Joffre Olaya
Selection of targets for deep brain stimulation (DBS) has been based on clinical experience, but inconsistent and unpredictable outcomes have limited its use in patients with heterogeneous or rare disorders. In this large case series, a novel staged procedure for neurophysiological assessment from 8 to 12 temporary depth electrodes is used to select targets for neuromodulation that are tailored to each patient's functional needs. Thirty children and young adults underwent deep brain stimulation target evaluation with the new procedure: Stereotactic Awake Basal ganglia Electrophysiological Recording and Stimulation (SABERS)...
February 26, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38387869/structural-alterations-of-the-corpus-callosum-in-children-with-infantile-hydrocephalus
#18
JOURNAL ARTICLE
Derya Adil, Emma G Duerden, Roy Eagleson, Sandrine de Ribaupierre
This study investigates structural alterations of the corpus callosum in children diagnosed with infantile hydrocephalus. We aim to assess both macrostructural (volume) and microstructural (diffusion tensor imaging metrics) facets of the corpus callosum, providing insights into the nature and extent of alterations associated with this condition. Eighteen patients with infantile hydrocephalus (mean age = 9 years) and 18 age- and sex-matched typically developing healthy children participated in the study...
February 22, 2024: Journal of Child Neurology
https://read.qxmd.com/read/38751190/the-contribution-of-psychological-symptoms-to-cognitive-difficulties-in-youth-with-postural-orthostatic-tachycardia-syndrome-and-chronic-pain
#19
JOURNAL ARTICLE
Michele Tsai Owens, Philip R Fischer, Leslie Sim, Alexandra Kirsch, Kendra Homan, Michael Zaccariello, Nicholas Sawchuk, Allison LeMahieu, Jennifer Geske, Cynthia Harbeck-Weber
INTRODUCTION: Subjectively experienced cognitive difficulties are common in youth with postural orthostatic tachycardia syndrome. The pathophysiological and psychological contributions of these cognitive impairments remain unclear. METHOD: Participants were 96 adolescents and young adults diagnosed with postural orthostatic tachycardia syndrome and admitted to an intensive pain treatment program. Participants completed cognitive assessment and measures of postural orthostatic tachycardia syndrome symptoms, pain intensity, pain catastrophizing, anxiety, depression, and functional disability...
March 2024: Journal of Child Neurology
https://read.qxmd.com/read/38351705/the-use-of-botulinum-toxin-type-a-in-medically-refractory-pediatric-patients-with-chronic-daily-headaches-and-its-impact-on-the-quality-of-life
#20
JOURNAL ARTICLE
Asra Akbar, Jenna Ford, Sandeep Tripathi
Background: Chronic migraine in children has been a challenging condition to treat, prompting the investigation of alternative therapies. This retrospective single-center chart review aimed to evaluate the efficacy and safety of Botox injections for managing chronic migraine in children. Methods: The study included children with chronic daily headaches and chronic migraine who were medically refractory to previous treatments at OSF Healthcare/Illinois Neurological Institute, Peoria, between 2015 and 2021. Botox injections were administered quarterly following a specific protocol...
February 13, 2024: Journal of Child Neurology
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