Sharmistha Das, Moumita Malik, Debabrata Ghosh Dastidar, Ritwik Roy, Payel Paul, Sarita Sarkar, Poulomi Chakraborty, Alakesh Maity, Monikankana Dasgupta, Anirban Das Gupta, Sudipta Chatterjee, Ranojit Kumar Sarker, Debasish Maiti, Prosun Tribedi
Methicillin-resistant Staphylococcus aureus (MRSA), a drug-resistant human pathogen causes several nosocomial as well as community-acquired infections involving biofilm machinery. Hence, it has gained a wide interest within the scientific community to impede biofilm-induced MRSA-associated health complications. The current study focuses on the utilization of a natural bioactive compound called piperine to control the biofilm development of MRSA. Quantitative assessments like crystal violet, total protein recovery, and fluorescein-di-acetate (FDA) hydrolysis assays, demonstrated that piperine (8 and 16 μg/mL) could effectively compromise the biofilm formation of MRSA...
February 27, 2024: Microbial Pathogenesis