Qing Li, Zongjing Yang, Xingqing Ling, Junming Ye, Jiaying Wu, Yu Wang, Chun Yao, Jinghui Zheng
OBJECTIVE: Tumor microenvironment (TME) research can provide a crucial direction for the innovation and continuous improvement of novel biologic therapies for cancer. This study examined the relationship between the TME, expression profiles of the tumor-infiltrating immune cell, and prognostic gene expression in ovarian cancer (OC). MATERIALS AND METHODS: Screening of CD3E, CD3G, CD2, CD3D, CCL19, and IL2RG was performed using the bioinformatics methods. RESULTS: All six genes were found to participate in immune-related molecular mechanisms and could regulate the expression of tumor-infiltrating cells...
2023: Disease Markers