journal
Journals Strahlentherapie und Onkologie...

Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et Al]

https://read.qxmd.com/read/38600366/advances-and-residual-knowledge-gaps-in-the-neck-management-of-head-and-neck-squamous-cell-carcinoma-patients-with-advanced-nodal-disease-undergoing-definitive-chemo-radiotherapy-for-their-primary
#1
REVIEW
Florent Carsuzaa, Emilien Chabrillac, Pierre Yves Marcy, Hisham Mehanna, Juliette Thariat
PURPOSE: Substantial changes have been made in the neck management of patients with head and neck squamous cell carcinomas (HNSCC) in the past century. These have been fostered by changes in cancer epidemiology and technological progress in imaging, surgery, or radiotherapy, as well as disruptive concepts in oncology. We aimed to review changes in nodal management, with a focus on HNSCC patients with nodal involvement (cN+) undergoing (chemo)radiotherapy. METHODS: A narrative review was conducted to review current advances and address knowledge gaps in the multidisciplinary management of the cN+ neck in the context of (chemo)radiotherapy...
April 10, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38578509/reply-to-letter-to-the-editor-reply-to-comparison-of-patient-setup-accuracy-for-optical-surface-guided-and-x-ray-guided-imaging-with-respect-to-the-impact-on-intracranial-stereotactic-radiotherapy
#2
LETTER
M Schöpe, J Sahlmann, S Jaschik, A Findeisen, G Klautke
No abstract text is available yet for this article.
April 5, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38578508/letter-to-the-editor-reply-to-comparison-of-patient-setup-accuracy-for-optical-surface-guided-and%C3%A2-x-ray-guided-imaging-with-respect-to-the-impact-on-intracranial-stereotactic-radiotherapy
#3
LETTER
Adi Robinson
No abstract text is available yet for this article.
April 5, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38546749/sarcopenia-is-associated-with-chemoradiotherapy-discontinuation-and-reduced-progression-free-survival-in-glioblastoma-patients
#4
JOURNAL ARTICLE
Fabian M Troschel, Benjamin O Troschel, Maren Kloss, Johanna Jost, Niklas B Pepper, Amelie S Völk-Troschel, Rainer G Wiewrodt, Walter Stummer, Dorothee Wiewrodt, Hans Theodor Eich
PURPOSE: Sarcopenia may complicate treatment in cancer patients. Herein, we assessed whether sarcopenia measurements derived from radiation planning computed tomography (CT) were associated with complications and tumor progression during radiochemotherapy for glioblastoma. METHODS: Consecutive patients undergoing radiotherapy planning for glioblastoma between 2010 and 2021 were analyzed. Retrocervical muscle cross-sectional area (CSA) was measured via threshold-based semi-automated radiation planning CT analysis...
March 28, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38530418/patient-reported-symptoms-before-adjuvant-locoregional-radiotherapy-for-breast-cancer-triple-negative-histology-impacts-the-symptom-burden
#5
JOURNAL ARTICLE
Carsten Nieder, Silje K Johnsen, Annette M Winther, Bård Mannsåker
BACKGROUND: Multimodal breast cancer treatment may cause side effects reflected in patient-reported outcomes and/or symptom scores at the time of treatment planning for adjuvant radiotherapy. In our department, all patients have been assessed with the Edmonton Symptom Assessment System (ESAS; a questionnaire addressing 11 major symptoms and wellbeing on a numeric scale of 0-10) at the time of treatment planning since 2016. In this study, we analyzed ESAS symptom severity before locoregional radiotherapy...
March 26, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38498173/enhancing-the-prediction-of-symptomatic-radiation-pneumonitis-for-locally-advanced-non-small-cell-lung-cancer-by-combining-3d-deep-learning-derived-imaging-features-with-dose-volume-metrics-a%C3%A2-two-center-study
#6
JOURNAL ARTICLE
Yan Kong, Mingming Su, Yan Zhu, Xuan Li, Jinmeng Zhang, Wenchao Gu, Fei Yang, Jialiang Zhou, Jianjiao Ni, Xi Yang, Zhengfei Zhu, Jianfeng Huang
OBJECTIVE: This study aims to examine the ability of deep learning (DL)-derived imaging features for the prediction of radiation pneumonitis (RP) in locally advanced non-small-cell lung cancer (LA-NSCLC) patients. MATERIALS AND METHODS: The study cohort consisted of 90 patients from the Fudan University Shanghai Cancer Center and 59 patients from the Affiliated Hospital of Jiangnan University. Occurrences of RP were used as the endpoint event. A total of 512 3D DL-derived features were extracted from two regions of interest (lung-PTV and PTV-GTV) delineated on the pre-radiotherapy planning CT...
March 18, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38488902/degro-guideline-for-personalized-radiotherapy-of-brain-metastases-and-leptomeningeal-carcinomatosis-in-patients-with-breast-cancer
#7
REVIEW
Kai J Borm, Sophie T Behzadi, Juliane Hörner-Rieber, David Krug, Rene Baumann, Stefanie Corradini, Marciana Nona Duma, Jürgen Dunst, Gerd Fastner, Petra Feyer, Rainer Fietkau, Wulf Haase, Wolfgang Harms, Thomas Hehr, Christiane Matuschek, Marc D Piroth, Leonard Christopher Schmeel, Rainer Souchon, Vratislav Strnad, Wilfried Budach, Stephanie E Combs
PURPOSE: The aim of this review was to evaluate the existing evidence for radiotherapy for brain metastases in breast cancer patients and provide recommendations for the use of radiotherapy for brain metastases and leptomeningeal carcinomatosis. MATERIALS AND METHODS: For the current review, a PubMed search was conducted including articles from 01/1985 to 05/2023. The search was performed using the following terms: (brain metastases OR leptomeningeal carcinomatosis) AND (breast cancer OR breast) AND (radiotherapy OR ablative radiotherapy OR radiosurgery OR stereotactic OR radiation)...
March 15, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38488901/radiotherapy-in-localized-prostate-cancer-a%C3%A2-multicenter-analysis-evaluating-tumor-control-and-late-toxicity-after-brachytherapy-and-external-beam-radiotherapy-in-1293-patients
#8
JOURNAL ARTICLE
Matthias Moll, Elisabeth Nechvile, Christian Kirisits, Oxana Komina, Thomas Pajer, Bettina Kohl, Marcin Miszczyk, Joachim Widder, Tomas-Hendrik Knocke-Abulesz, Gregor Goldner
BACKGROUND AND PURPOSE: Comparing oncological outcomes and toxicity after primary treatment of localized prostate cancer using HDR- or LDR-mono-brachytherapy (BT), or conventionally (CF) or moderately hypofractionated (HF) external beam radiotherapy. MATERIALS AND METHODS: Retrospectively, patients with low- (LR) or favorable intermediate-risk (IR) prostate cancer treated between 03/2000 and 09/2022 in two centers were included. Treatment was performed using either CF with total doses between 74 and 78 Gy, HF with 2...
March 15, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38488900/spinal-and-cervical-nodal-metastases-in-a%C3%A2-patient-with-glioblastoma
#9
JOURNAL ARTICLE
Silvio Heinig, Thomas Aigner, Heinz-Georg Bloß, Gerhard G Grabenbauer
This article presents the rare case of a 54-year-old gentleman with primary glioblastoma developing multiple extracranial metastases 7 months after diagnosis. Initially, the patient complained of progressive headaches, confusion, and weakness of the left arm. Magnetic resonance imaging of the brain showed a right temporoparietal tumor with substantial surrounding subcortical edema and midline shift to the left. Two consecutive craniotomies resulted in complete microsurgical resection of the lesion...
March 15, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38488899/assessment-and-validation-of-glottic-motion-using-cone-beam-ct-and-real-time-cine-mri
#10
JOURNAL ARTICLE
Seok-Joo Chun, Jaeman Son, Seonghee Kang, Chang Heon Choi, Jung-In Kim, Young-Il Kim, Joo Ho Lee, Jin Ho Kim, Hong-Gyun Wu
PURPOSE: This study aimed to assess the margin for the planning target volume (PTV) using the Van Herk formula. We then validated the proposed margin by real-time magnetic resonance imaging (MRI). METHODS: An analysis of cone-beam computed tomography (CBCT) data from early glottic cancer patients was performed to evaluate organ motion. Deformed clinical target volumes (CTV) after rigid registration were acquired using the Velocity program (Varian Medical Systems, Palo Alto, CA, USA)...
March 15, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38483569/-staphylococcus-aureus-colonization-as-a%C3%A2-risk-factor-for-acute-radiation-dermatitis
#11
JOURNAL ARTICLE
Nwabata Oji
No abstract text is available yet for this article.
March 14, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38466403/survival-outcomes-and-treatment-experience-of-124%C3%A2-patients-with-primary-central-nervous-system-lymphoma
#12
JOURNAL ARTICLE
Ziqing Tang, Geting Wu, Fang Tan, Yang Long, Jidong Hong, Zhiping Lyu, Rui Wei
PURPOSE: Primary central nervous system lymphoma (PCNSL) is a rare malignancy of the central nervous system with high invasiveness. There is little consensus on the treatment of PCNSL. This study retrospectively studied data from PCNSL patients in a single center to summarize treatment experience and explore prognostic factors. METHODS: Survival curves were drawn using the Kaplan-Meier method and prognostic factors were analyzed using Cox's hazards model...
March 11, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38453699/vitexin-enhances-radiosensitivity-of-mouse-subcutaneous-xenograft-glioma-by-affecting-the-mir-17-5p-mir-130b-3p-pten-hif-1%C3%AE-pathway
#13
JOURNAL ARTICLE
Tao Xie, Yu-Hao Ding, Chun-Sheng Sang, Ze-Xi Lin, Jun Dong, Xi-An Fu
PURPOSE: Vitexin can cooperate with hyperbaric oxygen to sensitize the radiotherapy of glioma by inhibiting the hypoxia-inducible factor (HIF)-1α. However, whether vitexin has a direct radiosensitization and how it affects the HIF-1α expression remain unclear. This study investigated these issues. METHODS: The SU3 cells-inoculated nude mice were divided into control, radiation, and vitexin + radiation groups. The vitexin + radiation-treated mice were intraperitoneally injected with 75 mg/kg vitexin daily for 21 days...
March 7, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38453698/visual-hallucinations-after-resection-of-cerebral-metastases-two-patients-with-complex-phantom-images
#14
JOURNAL ARTICLE
A Ovchinnikov, L Andereggen, S Rogers, M Gschwind
PURPOSE: Complex visual hallucinations are rarely seen in neurooncology. They are commonly observed alongside psychotic symptoms in schizophrenia or dementia, in Parkinson's or Lewy-body disease, after opioid medications or anesthesia, and, in particular, they appear with visual impairments. METHODS: Here we report two normal-sighted and mentally healthy patients with unusual visual hallucinations after the resection and irradiation of brain metastases, the main features of which were persistent colorful and meaningful images with hallucinatory perseveration...
March 7, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38421432/-nintedanib-for-the-treatment-of-radiation-pneumonitis
#15
JOURNAL ARTICLE
Cas Stefaan Dejonckheere, Ulrike Höller, Lukas Käsmann
No abstract text is available yet for this article.
February 29, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38418653/cost-benefit-ratio-of-modern-medical-education-using-micro-costing-a%C3%A2-model-calculation-using-the-example-of-an-innovative-breast-brachytherapy-workshop
#16
JOURNAL ARTICLE
Stefan Knippen, Marciana-Nona Duma, Michael Schwedas, Steffen Schrott, Sonja Drozdz, Irina Mäurer, Guido Hildebrandt, Matthias Mäurer
BACKGROUND AND PURPOSE: Radiation oncology is an essential component of therapeutic oncology and necessitates well-trained personnel. Multicatheter brachytherapy (MCBT) is one radiotherapeutic option for early-stage breast cancer treatment. However, specialized hands-on training for MCBT is not currently included in the curriculum for residents. A recently developed hands-on brachytherapy workshop has demonstrated promising results in enhancing knowledge and practical skills. Nevertheless, these simulation-based teaching formats necessitate more time and financial resources...
February 28, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38416163/longer-time-to-testosterone-recovery-impacts-favorably-on-outcomes-for-prostate-cancer-following-androgen-deprivation-and-radiotherapy
#17
JOURNAL ARTICLE
Susana Castro-Larefors, Maria Magdalena Marti-Laosa, Veronica Lopez-Honrubia, Irene Rey-Lopez, Beatriz Ruiz-Herrero, Yasmina Murria-Perez, Ignacio Andres, Isabel Elvira Jimenez-Garcia, Roberto Berenguer, Manuel Aguayo-Martos, Ricardo Sánchez-Prieto, Angeles Rovirosa, Esther Jimenez-Jimenez, Meritxell Arenas, Sebastià Sabater
PURPOSE: To evaluate the impact of sustained hypogonadism after androgen deprivation therapy (ADT) associated with radiotherapy in prostate cancer (PCa) patients with biochemical relapse-free survival (bRFS). METHODS: A retrospective cohort analysis of 213 consecutive PCa patients referred for radiotherapy plus ADT was carried out. Follow-up times including time to testosterone recovery (TTR) and bRFS were calculated from the end of ADT. Univariate and multivariate Cox regression analyses predicting bRFS were used...
February 28, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38409394/transrectal-ultrasound-for-intraoperative-interstitial-needle-guidance-in-cervical-cancer-brachytherapy
#18
JOURNAL ARTICLE
J Knoth, A Sturdza, A Zaharie, V Dick, G Kronreif, N Nesvacil, J Widder, C Kirisits, M P Schmid
OBJECTIVE: This study aimed to prospectively assess the visibility of interstitial needles on transrectal ultrasound (TRUS) in cervical cancer brachytherapy patients and evaluate its impact on implant and treatment plan quality. MATERIAL AND METHODS: TRUS was utilized during and after applicator insertion, with each needle's visibility documented through axial images at the high-risk clinical target volume's largest diameter. Needle visibility on TRUS was scored from 0 (no visibility) to 3 (excellent discrimination, margins distinct)...
February 26, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38396139/-hypoxia-based-de-escalation-of-radiochemotherapy-in-patients-with-human-papillomavirus-related-oropharyngeal-carcinoma
#19
JOURNAL ARTICLE
Alexander Rühle, Nils H Nicolay
No abstract text is available yet for this article.
February 23, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/38393398/radiotherapy-statements-of-the-18th-st-%C3%A2-gallen-international-breast-cancer-consensus-conference-a%C3%A2-german-expert-perspective
#20
REVIEW
David Krug, Maggie Banys-Paluchowski, Sara Y Brucker, Carsten Denkert, Nina Ditsch, Peter A Fasching, Renate Haidinger, Nadia Harbeck, Jörg Heil, Jens Huober, Christian Jackisch, Wolfgang Janni, Hans-Christian Kolberg, Sibylle Loibl, Diana Lüftner, Marion van Mackelenbergh, Julia C Radosa, Toralf Reimer, Manfred Welslau, Rachel Würstlein, Michael Untch, Wilfried Budach
PURPOSE: To summarize the radiotherapy-relevant statements of the 18th St. Gallen Breast Cancer Consensus Conference and interpret the findings in light of German guideline recommendations. METHODS: Statements and voting results from the 18th St. Gallen International Breast Cancer Consensus Conference were collected and analyzed according to their relevance for the radiation oncology community. The voting results were discussed in two hybrid meetings among the authors of this manuscript on March 18 and 19, 2023, in light of the German S3 guideline and the 2023 version of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) guidelines...
February 23, 2024: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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