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Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]

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https://read.qxmd.com/read/31098680/abstracts-degro-2019
#1
(no author information available yet)
No abstract text is available yet for this article.
May 9, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31073701/-primary-radiotherapy-and-short-androgen-deprivation-therapy-of-18-months-may-be-sufficient-in-patients-with-localized-prostate-cancer-with-high-risk-factor-compared-to-the-standard-of-28-to-36-months
#2
Dirk Böhmer, Felix Sedlmayer, Thomas Wiegel, Frank Wolf
No abstract text is available yet for this article.
May 9, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31065727/22nd-annual-sasro-meeting
#3
(no author information available yet)
No abstract text is available yet for this article.
May 7, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31049597/-efficacy-and-safety-of-carbon-ion-radiotherapy-for-locally-recurrent-rectal-cancer-results-of-the-j%C3%A2-cros-study-1404-rectum
#4
Christina Jentsch, Esther G C Troost
No abstract text is available yet for this article.
May 2, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31037351/automatic-image-segmentation-based-on-synthetic-tissue-model-for-delineating-organs-at-risk-in-spinal-metastasis-treatment-planning
#5
Olaf Wittenstein, Patrick Hiepe, Lars Henrik Sowa, Elias Karsten, Iris Fandrich, Juergen Dunst
PURPOSE: One of the main goals in software solutions for treatment planning is to automatize delineation of organs at risk (OARs). In this pilot feasibility study a clinical validation was made of computed tomography (CT)-based extracranial auto-segmentation (AS) using the Brainlab Anatomical Mapping tool (AM). METHODS: The delineation of nine extracranial OARs (lungs, kidneys, trachea, heart, liver, spinal cord, esophagus) from clinical datasets of 24 treated patients was retrospectively evaluated...
April 29, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31028406/pattern-of-failure-in-anaplastic-glioma-patients-with-an-idh1-2-mutation
#6
M Back, D Jayamanne, D Brazier, A Newey, D Bailey, G Schembri, E Hsiao, M Khasraw, M Wong, M Kastelan, C Brown, H Wheeler
PURPOSE: The current study aimed to assess patterns of failure (PoF) in anaplastic glioma (AG) patients managed with intensity-modulated radiation therapy (IMRT) and their relationship to molecular subtype. METHODS: The outcomes of AG patients managed between 2008 and 2014 and entered into a prospective database were assessed, including PoF. AG was initially defined using the WHO 2007 classification, but for analysis, patients were subsequently recategorised based on WHO 2016 as anaplastic oligodendroglioma (AOD), astrocytoma isocitrate dehydrogenase (IDH) mutant (AAmut) or astrocytoma IDH wildtype (AAwt)...
April 26, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31025053/a-dedicated-cloud-system-for-real-time-upfront-quality-assurance-in-pediatric-radiation-therapy
#7
Silvia Meroni, Claudia Cavatorta, Salvina Barra, Francesca Cavagnetto, Giovanni Scarzello, Alessandro Scaggion, Emilia Pecori, Barbara Diletto, Ombretta Alessandro, Maura Massimino, Stefano Gianolini, Emanuele Pignoli, Lorenza Gandola
PURPOSE: Pediatric radiotherapy (RT) is a highly specialized field, requiring great experience to delineate correctly tumor targets and organs at risk. To reduce treatment failures related to planning inaccuracies and to obtain robust clinical results despite the limited numbers of enrolled pediatric patients, the SIOP PNET5MB clinical trial on medulloblastoma requires a real-time, pre-radiation review of the RT treatment (craniospinal irradiation and boost plan) under the direct responsibility of the national coordinator center...
April 25, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31001645/-whole-or-partial-breast-radiotherapy-after-5-years-from-a-patient-perspective-longitudinal-analysis-of-the-import-low-cruk-06-003-phase-iii-trial
#8
David Krug, Jürgen Dunst
No abstract text is available yet for this article.
April 18, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/31001644/-vitamin-d-and-omega-3-fatty-acid-supplementation-does-not-reduce-the-cancer-and-cardiovascular-risk
#9
Florian Lordick
No abstract text is available yet for this article.
April 18, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30997541/the-impact-of-vaginal-dilator-use-on-vaginal-stenosis-and-sexual-quality-of-life-in-women-treated-with-adjuvant-radiotherapy-for-endometrial-cancer
#10
Sati Akbaba, Jan T Oelmann-Avendano, David Krug, Nathalie Arians, Tilman Bostel, Juliane Hoerner-Rieber, Nils H Nicolay, Juergen Debus, Katja Lindel, Robert Foerster
BACKGROUND: Despite a lack of evidence and low compliance, current guidelines recommend the use of a vaginal dilator (VD) after pelvic radiotherapy (RT). We analyzed the effect of VD on vaginal stenosis (VS) and its influence on sexual quality of life (QoL) in women treated with adjuvant RT for endometrial cancer (EC). METHODS: Between 2014 and 2015, 56 consecutive patients were instructed to use a VD after completion of treatment. The maximum diameter of the comfortably introducible VD was measured before and at 1 year after treatment...
April 17, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30997540/influence-of-xrcc4-expression-by-breast-cancer-cells-on-ipsilateral-recurrence-after-breast-conserving-therapy
#11
Mio Kitagawa, Masanori Someya, Tomokazu Hasegawa, Toshihiko Mikami, Kazuaki Asaishi, Tadashi Hasegawa, Yoshihisa Matsumoto, Goro Kutomi, Ichiro Takemasa, Koh-Ichi Sakata
BACKGROUND: We examined the expression of nonhomologous end-joining (NHEJ) proteins by breast cancer cells in patients with or without ipsilateral breast tumor recurrence (IBTR) after breast-conserving therapy. We also investigated whether there was a difference of NHEJ-related protein expression by tumor cells between two types of IBTR, i.e., true recurrence (TR) with regrowth from the tumor bed or development of a new primary tumor (NP). PATIENTS AND METHODS: The original cohort comprised 560 breast cancer patients who received breast-conserving therapy between February 1995 and March 2006, including 520 patients without IBTR and 40 patients with IBTR...
April 17, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30989242/acute-severe-lymphopenia-by-radiotherapy-is-associated-with-reduced-overall-survival-in-hepatocellular-carcinoma
#12
Hwa Kyung Byun, Nalee Kim, Sangjoon Park, Jinsil Seong
PURPOSE: Radiotherapy (RT) for peripheral organs can affect circulating lymphocytes and cause lymphopenia. We aimed to investigate RT-related lymphopenia in patients with hepatocellular carcinoma (HCC). METHODS: Medical records of 920 patients who received RT for HCC during 2001-2016 were reviewed. Total lymphocyte count (TLC) were obtained and analyzed for clinical outcome. Acute severe lymphopenia (ASL) was defined as TLC <500/μL within the first 3 months of the start of RT...
April 15, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30972454/retroperitoneal-soft-tissue-sarcoma-low-dose-neoadjuvant-radiation-therapy-followed-by-surgery-with-or-without-intraoperative-radiotherapy-and-adjuvant-radiation-therapy
#13
Simon Kirste, Nicole Landenberger, Jutta Scholber, Karl Henne, Uwe A Wittel, Anca-Ligia Grosu
BACKGROUND: We describe the clinical history, outcome, and toxicity of five patients with high-grade retroperitoneal soft tissue sarcoma (RSTS) who were treated with neoadjuvant low-dose radiotherapy (RT) followed by resection with or without intraoperative radiotherapy (IORT), followed by adjuvant RT. We aim to provide additional evidence for the various treatment options that exist for this rare tumor entity. METHODS: Most patients presented with mild abdominal symptoms...
April 10, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30972453/consolidative-mediastinal-irradiation-of-malignant-lymphoma-using-active-scanning-proton-beams-clinical-outcome-and-dosimetric-comparison
#14
Laila König, Nina Bougatf, Juliane Hörner-Rieber, Naved Chaudhri, Thomas Mielke, Sebastian Klüter, Matthias Felix Haefner, Stefan Rieken, Thomas Haberer, Jürgen Debus, Klaus Herfarth
PURPOSE: Current research approaches in lymphoma focus on reduction of therapy-associated long-term side effects. Especially in mediastinal lymphoma, proton beam radiotherapy (PT) may be a promising approach for reducing the dose to organs at risk (OAR). PATIENTS: In total, 20 patients were irradiated with active scanning PT at Heidelberg Ion Beam Therapy Center (HIT) between September 2014 and February 2017. For comparative analysis, additional photon irradiation plans with helical intensity-modulated radiotherapy (IMRT) were calculated and quantitative and qualitative dose evaluations were made for both treatment modalities...
April 10, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30963203/adapted-strategy-to-tumor-response-in-childhood-nasopharyngeal-carcinoma-the-french-experience
#15
Anaïs Jouin, Sylvie Helfre, Stéphanie Bolle, Line Claude, Anne Laprie, Emilie Bogart, Céline Vigneron, Hélène Potet, Anne Ducassou, Audrey Claren, François Georges Riet, Marie Pierre Castex, Cécile Faure-Conter, Brice Fresneau, Anne Sophie Defachelles, Daniel Orbach
PURPOSE: The aim of this study was to retrospectively study survival and long-term morbidities of children with nasopharyngeal carcinoma (NPC) treated by induction chemotherapy and concurrent chemoradiation (CRT). The total dose of radiation was adapted to the response following neoadjuvant chemotherapy. METHODS: Children with non-metastatic NPC treated in France between 1999 and 2015 were retrospectively included in the study. The strategy combined neoadjuvant platinum-based chemotherapy, followed by adapted CRT to tumor response...
April 8, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30953081/reply-to-combination-of-brachytherapy-and-chemotherapy-not-superior-to-pelvic-radiotherapy-according-to-gog-249
#16
LETTER
S Marnitz
No abstract text is available yet for this article.
April 5, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30949720/-radiosurgery-and-surgical-neurovascular-decompression-are-almost-equal-for-treatment-of-trigeminal-neuralgia
#17
Christoph Straube, Ehab Shiban, Bernhard Meyer, Stephanie E Combs
No abstract text is available yet for this article.
April 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30949719/-durvalumab-after-chemoradiotherapy-is-currently-the-most-promising-treatment-for-stage-iii-nsclc
#18
Martin Wilhelm
No abstract text is available yet for this article.
April 4, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30937509/re-irradiation-in-locally-recurrent-lung-cancer-patients
#19
Ingmar Schlampp, Juliane Rieber, Sebastian Adeberg, Farastuk Bozorgmehr, Claus Peter Heußel, Martin Steins, Jutta Kappes, Hans Hoffmann, Thomas Welzel, Jürgen Debus, Stefan Rieken
PURPOSE: Lung cancer remains one of the tumour diagnoses with high lethality, although innovative treatment approaches have yielded improvements in local control and survival rates. There is still no consensus on how to treat local relapse in patients after first-line treatments. Radiotherapy may be considered in this situation; however, data supporting its effectiveness are rare. The purpose of this retrospective analysis was to evaluate outcomes of patients re-irradiated for thoracic tumours in terms of overall survival (OS), local progression-free survival (LPFS), toxicity and dose-volume parameters...
April 1, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://read.qxmd.com/read/30937508/chemoradiotherapy-for-anal-cancer-are-we-as-good-as-we-think
#20
REVIEW
D Martin, C Rödel, E Fokas
Definitive chemoradiotherapy (CRT) is the standard treatment for anal squamous cell carcinoma (ASCC). Data regarding treatment outcome according to TNM classification is scarce. Here, we review data of randomized trials and retrospective cohorts suggesting a poor 3‑year disease-free survival (DFS; or progression-free survival, PFS) of approximately 60%, or even lower, in patients with locally advanced T3-4 and/or N+ disease, while patients with T1-2N0 ASCC have 3‑year DFS/PFS rates exceeding 80%. These results are in line with our data in a cohort of 210 patients with ASCC treated with definitive 5‑fluorouracil/mitomycin C‑based CRT to a total dose of 50...
April 1, 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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