Keisuke Matsuo, Ikuo Inoue, Takehide Matsuda, Takahide Arai, Shintaro Nakano
The absolute value of small dense low-density lipoprotein (sd-LDL) including small LDL (s-LDL) and very small LDL (vs-LDL) has been shown to be associated with increased incidence of atherosclerosis. However, the impact of short-timeframe increases in sd-LDL on arteriosclerosis has not yet been elucidated. Therefore, we investigated the clinical roles of ex-vivo induced sd-LDL in acute coronary syndrome (ACS) using a novel method. This is a prospective, single-blind, and observational study that screened patients who underwent coronary angiography (CAG) for the treatment of ACS or investigation of heart-failure etiology between June 2020 and April 2022 (n = 247)...
July 17, 2024: Heart and Vessels
Xiaohong Zhou
No abstract text is available yet for this article.
July 16, 2024: Heart and Vessels
Yuichiro Toma, Hidekazu Ikemiyagi, Shinya Shiohira, Haruno Nagata, Takaaki Nagano, Masashi Iwabuchi, Kojiro Furukawa, Kenya Kusunose
Transcatheter aortic valve replacement (TAVR) offers a solution, especially for high-risk aortic stenosis (AS) patients. However, patient outcomes post-TAVR show variability, highlighting the need for reliable prognostic indicators. Brachial-ankle pulse wave velocity (baPWV), a measure of arterial stiffness, may predict outcomes post-TAVR. This study aims to explore baPWV's prognostic value in relation to all-cause mortality post-TAVR. This study prospectively enrolled 212 severe AS patients undergoing TAVR between September 2015 and December 2021, focusing on pre- and post-TAVR baPWV measurements to explore associations with all-cause mortality...
July 15, 2024: Heart and Vessels
Yu Otsu, Masanari Kuwabara, Rieko Niitsu, Tetsuo Yamaguchi, Takahide Kodama
This study aimed to identify the clinical characteristics associated with spontaneous isolated dissection of superior mesenteric artery/celiac artery (SIDSMA/SIDCA). This observational study, conducted at Toranomon Hospital, Japan between 2009 and 2020, analyzed consecutive SIDSMA/SIDCA cases based on radiology data. The study compared clinical characteristics between symptomatic and asymptomatic patients with SIDSMA/SIDCA and investigated factors related to future vessel dilatation. Among 57 cases (44 SIDSMA, 17 SIDCA, and 4 both), the majority were male (87...
July 12, 2024: Heart and Vessels
Motoko Kametani, Yuichiro Minami, Hidetoshi Hattori, Shintaro Haruki, Junichi Yamaguchi
The HeartMate Risk Score (HMRS), a simple clinical prediction rule based on the patients' age, albumin, creatinine, and the international normalized ratio of the prothrombin time (PT-INR), is correlated with mortality in the cohort of left ventricular assist device (LVAD) recipients. However, in an aging society, an LAVD is indicated for only a small proportion of patients with acute heart failure (AHF), and whether the HMRS has prognostic implications for unselected patients with AHF is unknown. This study aimed to assess the prognostic value of HMRS categories on admission in patients with AHF...
July 10, 2024: Heart and Vessels
Shintaro Yoneyama, Makoto Hoyano, Kazuyuki Ozaki, Ryutaro Ikegami, Naoki Kubota, Takeshi Okubo, Takao Yanagawa, Takakuni Kurokawa, Takumi Akiyama, Yuzo Washiyama, Takeshi Kashimura, Takayuki Inomata
Continuous intravenous adenosine triphosphate (ATP) administration is the standard method for inducing maximal hyperemia in fractional flow reserve (FFR) measurements. Several cases have demonstrated fluctuations in the ratio of mean distal coronary pressure to mean arterial pressure (Pd/Pa) value during ATP infusion, which raised our suspicions of FFR value inaccuracy. This study aimed to investigate our hypothesis that Pd/Pa fluctuations may indicate inaccurate FFR measurements caused by insufficient hyperemia...
July 9, 2024: Heart and Vessels
Woong Gil Choi, Seung-Woon Rha, Byoung Geol Choi, Soohyung Park, Ji Bak Kim, Dong Oh Kang, Cheol Ung Choi, Yong Sung Seo, Yoon Hyung Cho, Sang Ho Park, Seung Jin Lee, Young Guk Ko, Ae-Young Her, Sang Min Kim, Ki Chang Kim, Jang Hyun Cho, Won Yu Kang, Joo Han Kim, Min Woong Kim, Do Hoi Kim, Jang Ho Bae, Ji Hoon Ahn, Sang Cheol Jo, Jae Bin Seo, Woo Young Jung, Sang Min Park
Iliac artery angioplasty with stenting is an effective alternative treatment modality for aortoiliac occlusive diseases. Few randomized controlled trials have compared the efficacy and safety between self-expandable stent (SES) and balloon-expandable stent (BES) in atherosclerotic iliac artery disease. In this randomized, multicenter study, patients with common or external iliac artery occlusive disease were randomly assigned in a 1:1 ratio to either BES or SES. The primary end point was the 1-year clinical patency, defined as freedom from any surgical or percutaneous intervention due to restenosis of the target lesion after the index procedure...
July 2, 2024: Heart and Vessels
Jia-Lin Yuan, Chuang-Xiong Hong
No abstract text is available yet for this article.
June 27, 2024: Heart and Vessels
Luca Paolucci, Fabio Mangiacapra, Michele Mattia Viscusi, Sara Sergio, Edoardo Bressi, Iginio Colaiori, Elisabetta Ricottini, Ilaria Cavallari, Annunziata Nusca, Rosetta Melfi, Gian Paolo Ussia, Francesco Grigioni
To evaluate if integrating platelet reactivity (PR) evaluation in the original age, creatinine and ejection fraction (ACEF) score could improve the diagnostic accuracy of the model in patients with stable coronary artery disease (CAD). We enrolled patients treated with percutaneous coronary intervention between 2010 and 2011. High PR was included in the model (PR-ACEF). Co-primary end points were a composite of death/myocardial infarction (MI) and major adverse cardiovascular events (MACE). Overall, 471 patients were enrolled...
June 24, 2024: Heart and Vessels
Yuki Hida, Teruhiko Imamura, Hiroshi Onoda, Kota Kakeshita, Koichiro Kinugawa
We often encounter patients with congestive heart failure refractory to conventional diuretics therapy. Kampo goreisan (Tsumura &Co. Tokyo, Japan) is receiving great concern in mediating body water balance, particularly for such a cohort. However, its detailed biological mechanism remains uncertain. Patients who received goreisan to treat congestive heart failure refractory to tolvaptan-incorporated medical therapy were prospectively included and observed for one week during the therapeutic period. The change in urine biomarkers during the first 24 h was assessed as a primary concern...
June 21, 2024: Heart and Vessels
Shuichi Kitada, Yu Kawada, Kosuke Nakasuka, Tatsuya Mizoguchi, Junki Yamamoto, Masashi Yokoi, Tsuyoshi Ito, Toshihiko Goto, Shohei Kikuchi, Yoshihiro Seo
Activated arginine vasopressin (AVP) pathway worsens congestion in heart failure (HF), but its potential to relieve pulmonary congestion is also reported. The pathophysiological role and prognostic utility of AVP elevation in acute decompensated HF (ADHF) are poorly understood. We prospectively enrolled 52 hospitalized patients for ADHF to investigate the association between acute lung injury (ALI) in ADHF and AVP levels on admission. ALI was defined as respiratory failure leading to death, or requiring a respirator or a more than 12-h non-invasive intermittent positive pressure ventilation (NIPPV) support...
June 11, 2024: Heart and Vessels
Takahiro Yamashita, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Takunori Tsukui, Masashi Hatori, Taku Kasahara, Yusuke Watanabe, Kei Yamamoto, Masaru Seguchi, Hideo Fujita
Although serum troponin level is the gold standard under the universal definition of acute myocardial infarction (AMI), serum creatinine kinase (CK) and creatine kinase-myocardial band (CK-MB) is still measured in clinical practice as the compliment of troponin level. The purpose of this retrospective study is to illustrate the dramatic change of CK-MB/CK ratio by comparing CK-MB/CK ratio in patients with ST-segment elevation myocardial infarction (STEMI) among ≤ 24 h before reaching peak CK, peak CK, ≤ 24 h after reaching peak CK, and 24-48 h after reaching peak CK...
June 8, 2024: Heart and Vessels
Makoto Haga, Shunya Shindo, Jun Nitta, Mitsuhiro Kimura, Shinya Motohashi, Hidenori Inoue, Junetsu Akasaka
The aim of this study was to identify anatomical and clinical factors associated with limb-based patency (LBP) loss, major adverse limb events (MALEs), and poor amputation-free survival (AFS) after an infrapopliteal arterial bypass (IAB) surgery according to the Global Limb Anatomic Staging System. A retrospective analysis of patients undergoing IAB surgery between January 2010 and December 2021 at a single institution was performed. Two-year AFS, freedom from LBP loss, and freedom from MALEs were assessed using the Kaplan-Meier method...
June 6, 2024: Heart and Vessels
Hirokazu Shimono, Akihiro Tokushige, Daisuke Kanda, Ayaka Ohno, Ryo Arikawa, Hideto Chaen, Hideki Okui, Naoya Oketani, Mitsuru Ohishi
High bleeding risk (HBR), as defined by the Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria, has been recently reported to be associated with an increased risk of major bleeding events and cardiovascular events. We investigated the association between the ARC-HBR score and clinical outcomes in patients with stable coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). We assessed 328 consecutive patients with stable CAD who underwent PCI between January 2017 and December 2020...
June 6, 2024: Heart and Vessels
Hironobu Sumiyoshi, Mikitaka Fujita, Naoki Nishiura, Kazunori Mushiake, Ryuki Chatani, Sachiyo Ono, Hiroshi Tasaka, Takeshi Maruo, Kazushige Kadota, Shunsuke Kubo
Currently, no consensus has been established on the most effective antithrombotic therapy to prevent thromboembolic and bleeding events in patients undergoing percutaneous left atrial appendage closure (LAAC) with preprocedural thromboembolic or bleeding events under oral anticoagulation (OAC) therapy. We retrospectively investigated the incidence of device-related thrombosis (DRT), thromboembolic events, and bleeding events in patients who underwent LAAC from September 2019 to October 2022. After categorizing patients into three groups based on preprocedural thromboembolic or bleeding events under OAC therapy, we compared the incidence of DRT and prognosis according to the postprocedural antithrombotic therapy...
June 5, 2024: Heart and Vessels
M A M Beijk, J A Winkelman, H M Eckmann, D A Samson, A P Widyanti, J Vleugels, D C M Bombeld, C G C M Meijer, H J Bogaard, A Vonk Noordegraaf, H A C M de Bruin-Bon, B J Bouma
BACKGROUND: Assessment of the pattern of the RV outflow tract Doppler provides insights into the hemodynamics of chronic thromboembolic pulmonary hypertension (CTEPH). We studied whether pre-operative assessment of timing of the pulmonary flow systolic notch by Doppler echocardiography is associated with long-term survival after pulmonary endarterectomy (PEA) for CTEPH. METHODS: Fifty-nine out of 61 consecutive CETPH patients (mean age 53 ± 14 years, 34% male) whom underwent PEA between June 2002 and June 2005 were studied...
June 5, 2024: Heart and Vessels
Yuji Kono, Masahiko Mukaino, Yushi Ozawa, Koji Mizutani, Yuki Senju, Takayuki Ogasawara, Masumi Yamaguchi, Takashi Muramatu, Hideo Izawa, Yohei Otaka
No abstract text is available yet for this article.
June 3, 2024: Heart and Vessels
Manabu Kashiwagi, Akio Kuroi, Natsuki Higashimoto, Kazuya Mori, Kosei Terada, Yosuke Katayama, Kazushi Takemoto, Akira Taruya, Yasutsugu Shiono, Takashi Tanimoto, Hironori Kitabata, Atsushi Tanaka
The relationship between subclinical atrial fibrillation (SCAF) and left pulmonary vein anatomy is unknown. This study sought to investigate whether left pulmonary vein trunk predict the development of SCAF in patients with cardiac implantable electronic device (CIED). We also examined the relationship between the duration of SCAF and left pulmonary vein trunk. We retrospectively enrolled 162 patients who underwent implantation of dual-chamber CIEDs and follow-up by remote monitoring system. Computed tomography was used to measure the length of the left pulmonary vein...
June 1, 2024: Heart and Vessels
Peng Jin, Qinggang Zhang
No abstract text is available yet for this article.
May 29, 2024: Heart and Vessels
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