Toshiki Tanigaki, Shingo Kato, Mai Azuma, Manabu Nitta, Nobuyuki Horita, Daisuke Utsunomiya
OBJECTIVE: The objective of this meta-analysis was to assess the clinical utility of anomalous discoveries on cardiac magnetic resonance, particularly the right ventricular extracellular volume (RV-ECV), among individuals who underwent surgical repair for Tetralogy of Fallot (rTOF). METHODS: We conducted a systematic search of electronic databases including PubMed, Web of Science Core Collection, Cochrane advanced search, and EMBASE. Our analysis involved a comparison of ECV levels between rTOF patients and controls, as well as an evaluation of the predictive value of ECV for future adverse events...
November 27, 2023: Heart and Vessels
Tsukasa Murakami, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Takunori Tsukui, Masashi Hatori, Yusuke Tamanaha, Taku Kasahara, Yusuke Watanabe, Kei Yamamoto, Masaru Seguchi, Hiroshi Wada, Hideo Fujita
Mechanical complication (MC) is a rare but serious complication in patients with ST-segment elevation myocardial infarction (STEMI). Although several risk factors for MC have been reported, a prediction model for MC has not been established. This study aimed to develop a simple prediction model for MC after STEMI. We included 1717 patients with STEMI who underwent primary percutaneous coronary intervention (PCI). Of 1717 patients, 45 MCs occurred after primary PCI. Prespecified predictors were determined to develop a tentative prediction model for MC using multivariable regression analysis...
November 27, 2023: Heart and Vessels
Takaomi Nomi, Akira Kitamura, Miki Tsujita, Yuki Shiko, Yohei Kawasaki, Hideyuki Nakagawa
Acute kidney injury (AKI) frequently occurs after cardiac surgery. Recently, transcatheter aortic valve implantation (TAVI), a less invasive option for aortic stenosis (AS), has been increasingly performed, particularly in elderly patients. We retrospectively investigated and compared the incidence and risk factors of postoperative AKI in patients who underwent surgical aortic valve replacement (SAVR) and TAVI. This was a retrospective single-center study. Seven days postoperatively, data were obtained from medical records...
November 17, 2023: Heart and Vessels
Yu Hosono, Ken Takahashi, Sachie Shigemitsu, Satoshi Akimoto, Mayumi Ifuku, Kana Yazaki, Hisako Wakatsuki, Akinori Yaguchi, Osamu Tomita, Junya Fujimura, Masahiro Saito, Daisuke Yoneoka, Toshiaki Shimizu
BACKGROUND: Cardiac dysfunction due to cardiotoxicity from anthracycline chemotherapy is a leading cause of morbidity and mortality in childhood cancer survivors (CCS), and the cumulative incidence of cardiac events has continued to increase. This study identifies an adequate indicator of cardiac dysfunction during long-term follow-up. PROCEDURE: In total, 116 patients (median age: 15.5 [range: 4.7-40.2] years) with childhood cancer who were treated with anthracycline were divided into three age groups for analysis (C1: 4-12 years of age, C2: 13-18 years of age, C3: 19-40 years of age), and 116 control patients of similar ages were divided into three corresponding groups (N1, N2, and N3)...
November 16, 2023: Heart and Vessels
Amr Alkassas, Yasser Elbarbary, Mohammed H Sherif, Shaimaa B El-Saied, Rasha Y Hagag, Mohammed Elbarbary
Acute kidney injury (AKI) is a common complication after Percutaneous Coronary Intervention (PCI) for ST segment elevation myocardial infarction (STEMI) and is associated with poor outcomes. AKI is diagnosed by the dynamic change of serum Cr, but it could not predict AKI. This study aimed to evaluate a biomarker array that may fulfill this shortage. Setting: Cardiology Department, Tanta University Hospital. Design: Prospective interventional study included 280 acute STEMI patients who underwent emergency PCI...
November 13, 2023: Heart and Vessels
Chang Hou, Yahui Lu, Yuliang Ma, Qi Li, Chuanfen Liu, Mingyu Lu, Chengfu Cao, Jian Liu
Fractional flow reserve (FFR) has been established as a gold standard for functional coronary ischemia. At present, the FFR can be calculated from coronary computed tomography angiography (CCTA) images (CT-FFR). Previous studies have suggested that CT-FFR outperforms CCTA and invasive coronary angiography (ICA) in determining hemodynamic significance of stenoses. Recently, a novel automatical algorithm of CT-FFR called RuiXin-FFR has been developed. The present study is designed to investigate the predictive value of this algorithm and its value in therapeutic decision making...
October 28, 2023: Heart and Vessels
Daisetsu Aoyama, Shinsuke Miyazaki, Naoki Amaya, Naoto Tama, Kanae Hasegawa, Ryohei Nomura, Toshihiko Tsuji, Akira Nakano, Hiroyasu Uzui, Hiroshi Tada
Clinical outcomes after catheter ablation in patients with reduced left ventricular (LV) ejection fraction (EF) and atrial fibrillation (AF) remain unclear. This study aimed to explore the clinical outcomes of patients with arrhythmia-induced cardiomyopathy (AIC) and the influence of pharmacological treatment on clinical outcomes in patients with AIC after the procedure. Ninety-six patients with AF with a reduced LVEF (LVEF < 50%, 66.7 ± 10.9 years; 72 males) underwent AF ablation...
October 23, 2023: Heart and Vessels
Teresa Miriam Pérez-Sanz, Itziar Gómez-Salvador, Pau Codina, Beatriz Calvo Antón, María Mar de la Torre Carpente, Belén Redondo Bermejo, Cristina Tapia Ballesteros
Soluble ST2 (sST2) is the expression of a pathogenic process related to adverse remodeling that ultimately leads to increased mortality in heart failure (HF). Risk score models provide a comprehensive approach for mortality prediction, beyond the use of biomarkers alone. The objective was to determine the additional value of sST2 and two well-validated contemporary risk scores, BCN-Bio-HF and MAGGIC-HF, in predicting mortality and readmission in the acute setting. This prospective study included 129 patients (mean age 75 ± 9 years; 52% males) after an urgent HF visit...
October 23, 2023: Heart and Vessels
Haruhiko Sugimori, Tatsuya Nakao, Yukikatsu Okada, Yutaka Okita, Hitoshi Yaku, Junjiro Kobayashi, Hideyuki Uesugi, Shuichiro Takanashi, Toshiaki Ito, Tadaaki Koyama, Taichi Sakaguchi, Kouji Yamamoto, Yasushi Yoshikawa, Yoshiki Sawa
This study retrospectively evaluated the mid-term outcomes of surgical aortic valve replacement (SAVR) using a stented porcine aortic valve bioprosthesis (Mosaic; Medtronic Inc., Minneapolis, MN, USA) with concomitant mitral valve (MV) repair. From 1999 to 2014, 157 patients (median [interquartile range] age, 75 [70-79] years; 47% women) underwent SAVR with concomitant MV repair (SAVR + MV repair), and 1045 patients (median [interquartile range] age, 76 [70-80] years; 54% women) underwent SAVR only at 10 centers in Japan as part of the long-term multicenter Japan Mosaic valve (J-MOVE) study...
October 16, 2023: Heart and Vessels
Yuji Kono, Masahiko Mukaino, Yushi Ozawa, Koji Mizutani, Yuki Senju, Takayuki Ogasawara, Masumi Yamaguchi, Takashi Muramatsu, Hideo Izawa, Yohei Otaka
The purposes of the present study were: (1) to investigate the relationship between hospital-associated functional decline (HAFD) and non-lying time and (2) to clarify the optimal cut-off value for non-lying time associated with HAFD in older patients undergoing transcatheter aortic valve implantation (TAVI). From January 2021 to December 2022, patients admitted to a university hospital who underwent trans-femoral TAVI were consecutively recruited. We measured short physical performance battery (SPPB) pre and post-TAVI, and non-lying time from post-operative days 3-5...
October 16, 2023: Heart and Vessels
Yujiro Homma, Minoru Takahashi, Koichi Fuse, Yuki Okamoto, Kazuo Yamamoto, Atsushi Kuwabara, Masaaki Okabe, Shinpei Yoshii, Kiminori Kato, Kohei Akazawa, Yoshifusa Aizawa
To examine reverse atrial electrical remodeling in patients with aortic stenosis (AS) after trans-catheter aortic valve replacement (TAVR). In 65 consecutive patients with severe AS (83 ± 4 years, 47 (72.3%) females), we analyzed ECG records for the P wave duration (PWD) in lead II and P-terminal force (PTFV1) in V1, and measured cardiac dimensions and function by echocardiography (ECHO) following TAVR. Biomarkers were measured to assess myocardial injury by TAVR. TAVR was successfully performed without major complications: the aortic valve area increased from 0...
October 16, 2023: Heart and Vessels
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October 11, 2023: Heart and Vessels
Shunsuke Tomomori, Kazuyoshi Suenari, Akinori Sairaku, Tadanao Higaki, Kazuoki Dai, Kuniomi Oi, Tomoharu Kawase, Norihiko Ohashi, Kenji Nishioka, Yoshiko Masaoka, Nobuo Shiode, Yukiko Nakano
Epicardial adipose tissue (EAT) has been reported to promote myocardial fibrosis and to affect intracardiac conduction. The PR interval reflects the conduction from the atria to the Purkinje fibers and may be associated with the EAT volume, especially in persistent atrial fibrillation (AF) patients. We aimed to investigate the relationship between the EAT and PR interval in patients with persistent AF. We enrolled 268 persistent AF patients who underwent catheter ablation (CA) and divided the patients into two groups: the normal PR interval group (PR interval less than 200 ms: Group N) and long PR interval group (PR interval 200 ms or more: Group L)...
October 9, 2023: Heart and Vessels
Hüseyin Durak, Mustafa Çetin, Nadir Emlek, Elif Ergül, Ali Gökhan Özyıldız, Ahmet Seyda Yılmaz, Hakan Duman, Haldun Koç, Muhammed Mürsel Öğütveren, Ahmet Özsipahi
The identification of interatrial block (IAB) through electrocardiography (ECG) has been correlated with an elevated likelihood of developing atrial fibrillation (AF) and stroke. IAB is diagnosed by evaluating P-wave prolongation on a surface ECG. The presystolic wave (PSW) is an echocardiographic marker determined by pulse-wave examination of the aortic root during late diastole. As IAB and PSW share similar pathophysiological mechanisms, we speculated that PSW, as a component of the P wave, might be useful in predicting IAB...
October 5, 2023: Heart and Vessels
Carlo A Mallio, Gianfranco Di Gennaro, Federico Greco, Andrea Pescosolido, Caterina Bernetti, Claudia Lucia Piccolo, Vitaliano Buffa, Carlo C Quattrocchi, Bruno Beomonte Zobel
Lipomatous hypertrophy of the interatrial septum (LHIS) is a benign cardiac mass determined by abnormal deposition of adipose tissue in the interatrial septum. The quantitative relationship between LHIS and visceral adiposity has not been explored to date.In this retrospective study, three groups of consecutive patients undergoing CT imaging were enrolled: L + with LHIS, L- without LHIS, and LO- without both LHIS and history of malignancies. Areas of total adipose tissue (TAT), visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT) and LHIS areas were calculated on CT images...
October 4, 2023: Heart and Vessels
Akiko Sakai, Michinobu Nagao, Atsushi Yamamoto, Risako Nakao, Shuji Sakai, Junichi Yamaguchi
Interstitial lung disease and cardiac involvement are common manifestations and prognostic factors of systemic sclerosis. However, it is unclear whether impaired right atrial function associated with interstitial lung disease in systemic sclerosis can be used as a prognostic factor in this patient population. Therefore, this study aimed to investigate the relationship between right atrial function, interstitial lung disease, and prognosis in patients with systemic sclerosis using tissue tracking analysis with cine cardiac magnetic resonance imaging...
October 1, 2023: Heart and Vessels
Ryota Kobayashi, Miki Sakazaki, Yukie Nagai, Takanobu Okamoto, Yuto Hashimoto, Kaori Sato, Shotaro Seki, Urara Hata, Kazuki Esaki, Ryuya Tanigawa, Amane Mitsuoka, Akiko Funaki, Yasuhiro Niki, Takeo Hashiguchi, Hideyuki Negoro
Endothelin-1 (ET-1), produced by vascular endothelial cells, plays a pivotal role in the regulation of vascular tone. Isomaltulose, a naturally occurring sweetener and structural isomer of sucrose, reduces postprandial hyperglycemia, but its effect on arteriosclerosis due to hyperglycemia is unknown. The effects of 12 weeks of isomaltulose administration on ET-1 levels, a peptide that regulates arterial stiffness, blood pressure, and vascular tone, were tested before and after an oral glucose tolerance test...
September 30, 2023: Heart and Vessels
Yanxia Zhang, Jieqiong Liu
To analyze the clinical value of echocardiography combined with serum lacuna protein-1 (Cav-1), activated T cell nuclear factor C1 (NFATc1), and plasminogen activator inhibitor-1 (PAI-1) in the diagnosis of Kawasaki disease (KD) complicated with coronary artery lesions (CAL). A total of 200 children with KD treated in our hospital from January 2019 to October 2021 were grouped as the KD alone group (n = 56) and the KD complicated with CAL group (n = 144) according to the results of coronary angiography...
September 27, 2023: Heart and Vessels
Olena Pankova, Oleksii Korzh
Catestatin (CST) is a pleiotropic peptide with cardioprotective and metabolic effects. CST is involved in the pathogenesis of both arterial hypertension (AH) and type 2 diabetes mellitus (T2DM), which are the risk factors of cardiovascular diseases. In this study, we aimed to investigate the plasma CST levels in hypertensive patients, especially with T2DM, as well as compare those with healthy volunteers, and explore the relationship between CST levels and clinical, anthropometric and laboratory parameters...
September 27, 2023: Heart and Vessels
Shizuya Shintomi, Satoshi Saito, Azumi Hamasaki, Yuki Ichihara, Kozo Morita, Masahiro Ikeda, Satoru Domoto, Akihisa Furuta, Hiroshi Niinami
Little is known regarding the long-term (> 10 years) outcomes and risk factors of total arterial coronary artery bypass grafting (CABG). This study evaluated the long-term outcomes and risk factors for all-cause mortality and major adverse cardiac and cerebrovascular events (MACCEs) following total arterial on-pump CABG (ONCAB) or off-pump CABG (OPCAB) with complete revascularization. This retrospective cohort analysis enrolled patients with stable angina who underwent total arterial CABG with complete revascularization in our institute between July 2000 and June 2019...
September 25, 2023: Heart and Vessels
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