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Heart and Vessels

Monami Ando, Yasuya Inden, Yukihiko Yoshida, Akinori Sairaku, Satoshi Yanagisawa, Hirohiko Suzuki, Ryo Watanabe, Masaki Takenaka, Mayuho Maeda, Toyoaki Murohara
In the original publication of the article, the table 2 was published incorrectly.
May 13, 2019: Heart and Vessels
Kathrin Weidner, Michael Behnes, Christel Weiß, Christoph Nienaber, Linda Reiser, Armin Bollow, Gabriel Taton, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Jonas Rusnak, Tobias Schupp, Seung-Hyun Kim, Christian Barth, Jorge Hoppner, Muharrem Akin, Kambis Mashayekhi, Martin Borggrefe, Ibrahim Akin
The study sought to assess the impact of chronic kidney disease (CKD) on recurrences of ventricular tachyarrhythmias in implantable cardioverter defibrillator (ICD) recipients. Data regarding the outcome of patients with CKD in ICD recipients is limited. A large retrospective registry was used including consecutive ICD recipients surviving episodes of ventricular tachycardia (VT) or fibrillation (VF) from 2002 to 2016. CKD patients were compared to non-CKD patients. The primary endpoint was the first recurrence of ventricular tachyarrhythmias at 5 years...
May 10, 2019: Heart and Vessels
Lu Zhang, Li Liu, Mei Ma, Shiqiang Cheng, Bolun Cheng, Ping Li, Yan Wen, Yanan Du, Xiao Liang, Yan Zhao, Miao Ding, Qi Xin, Chujun Liang, Huimei Huang, Feng Zhang
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia characterized by extensive structural, contractile and electrophysiological remodeling. The genetic basis of AF remained elusive until now. Transcriptome-wide association study (TWAS) was conducted by FUSION tool using gene expression weights of 7 tissues combined with a large-scale genome-wide association study (GWAS) dataset of AF, totally involving 8180 AF cases and 28,612 controls. Significant genes identified by TWAS were then subjected to gene ontology (GO) and pathway enrichment analysis...
May 7, 2019: Heart and Vessels
Koichi Akutsu, Hideaki Yoshino, Tomoki Shimokawa, Hitoshi Ogino, Takashi Kunihara, Toshiyuki Takahashi, Michio Usui, Kazuhiro Watanabe, Tetsuya Tobaru, Kenichi Hagiya, Wataru Shimizu, Tetsuya Niino, Mitsuhiro Kawata, Hiroshi Masuhara, Yoshinori Watanabe, Nobuko Yoshida, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
Acute aortic dissection (AAD) cases are thought to have high blood pressure (BP) on admission; however, little data are available on BP prior to admission. The purpose of this study was to investigate systolic blood pressure (SBP) very early after symptom onset and before hospital transfer in patients with AAD to determine whether SBPs were high, and also whether SBPs were higher or lower compared with SBPs at hospital admission. We obtained results using three-year data derived from the Tokyo Acute Aortic Super Network Database...
May 6, 2019: Heart and Vessels
Yume Nohara-Shitama, Hisashi Adachi, Mika Enomoto, Ako Fukami, Sachiko Nakamura, Shoko Kono, Nagisa Morikawa, Akiko Sakaue, Hitoshi Hamamura, Kenta Toyomasu, Yoshihiro Fukumoto
It is well known that subjects with metabolic syndrome show an elevated resting heart rate. We previously reported that elevated heart rate was significantly related to all-cause mortality, and that coffee consumption was inversely associated with metabolic syndrome. We hypothesized that higher coffee consumption may decrease all-cause mortality by reducing resting heart rate. We performed a longitudinal epidemiological study in Tanushimaru (a cohort of the Seven Countries Study). A total of 1920 residents aged over 40 years received health checkups in 1999...
May 6, 2019: Heart and Vessels
Sangmo Hong, Munsuk Nam, Bertis B Little, Seihyun Paik, Kwanwoo Lee, Jungtaek Woo, Dooman Kim, Jungoo Kang, Minyoung Chun, Yongsoo Park
Antiplatelet drugs are effective in preventing recurrence of atherosclerosis in type 2 diabetes (T2D) patients. However, the efficacy and usefulness of antiplatelet drugs on the progression of carotid intima-media thickness (IMT), a marker for evaluating early atherosclerotic vascular disease, has not been analyzed. We conducted a prospective, randomized, open, 36-month trial comparing cilostazol vs. aspirin. A total of 415 T2D patients (age range 38-83 years; 206 females) without macrovascular complications were randomized to either an aspirin (100 mg/day) or cilostazol (200 mg/day) treatment...
May 6, 2019: Heart and Vessels
Hideyuki Kishima, Takanao Mine, Eiji Fukuhara, Kenki Ashida, Masaharu Ishihara
The low-voltage areas of left atrium (LA-LVA) have recently been of significant focus. However, very few studies have focused on the association between LA function and LA-LVA, and the mechanism of appearance of LA-LVA remains unclear. We investigated the marker for the existence of LA-LVA using automated 3-D mapping system. We studied 92 patients (75 males, 68 ± 9 years, 47 non-paroxysmal AF) who received CA for AF and 40 control patients without AF. Echocardiography was performed before the CA, and high-density voltage mapping during sinus rhythm after pulmonary isolation was performed in AF patients...
May 2, 2019: Heart and Vessels
Tatsuro Ibe, Hiroshi Wada, Kenichi Sakakura, Seiichiro Yoshimura, Miyuki Ito, Yusuke Ugata, Kei Yamamoto, Masaru Seguchi, Yousuke Taniguchi, Shin-Ichi Momomura, Hideo Fujita
In patients with acute pulmonary thromboembolism (PTE), the influence of residual pulmonary hypertension (PH) has not been well investigated. The aim of this study was to compare clinical characteristics between patients with and without residual PH, and to investigate the association between residual PH and clinical outcomes after acute phase in acute PTE. We included acute PTE patients who underwent echocardiogram after acute phase between January 2009 and December 2016. These patients were divided into residual PH and non-residual PH groups according to the value of estimated right ventricular systolic pressure (eRVSP) by echocardiogram after acute phase (the residual PH group: eRVSP ≥ 40 mmHg, the non-residual PH group: eRVSP < 40 mmHg)...
May 2, 2019: Heart and Vessels
Koichi Ohashi, Daisuke Abe, Norihiro Kuroki, Takao Yuba, Kou Suzuki
The aim of this study was to investigate the incidence of binary restenosis and its predictors in patients with ostial lesions of the right coronary artery (RCAos) who underwent percutaneous coronary intervention (PCI). RCAos are associated with a high incidence of restenosis, and the implantations of drug-eluting stents for RCAos have not been fully elucidated. The study participants included 75 patients (72.3 ± 9.5 years, 72% men) who underwent PCI for RCAos at our institution between November 2001 and May 2017...
April 26, 2019: Heart and Vessels
Gensai Yamaura, Tetsu Watanabe, Harutoshi Tamura, Hayato Tsuchiya, Naoto Hashimoto, Masahiro Wanezaki, Satoshi Nishiyama, Takanori Arimoto, Hiroki Takahashi, So Yamauchi, Tetsuro Shishido, Tamon Yamanaka, Takuya Miyamoto, Masafumi Watanabe
Prolonged total atrial conduction time is caused by atrial remodeling. Left atrial remodeling is associated with poor outcome in patients with heart failure (HF). This study aimed to investigate whether prolonged total atrial conduction time predicts poor prognosis in patients with HF. We performed transthoracic echocardiography in 100 patients (65 men; mean age 68 ± 13 years) who were hospitalized for HF. Total atrial conduction time was defined as the duration from P wave onset on electrocardiography to peak A' wave on tissue Doppler imaging (TDI) echocardiography (PA-TDI duration)...
April 26, 2019: Heart and Vessels
Takashi Yoshizane, Shinichiro Tanaka, Shintaro Abe, Takahiro Ueno, Yoshiaki Goto, Tai Kojima, Makoto Iwama, Masazumi Arai, Toshiyuki Noda, Masanori Kawasaki
Pathological studies have suggested the different process of in-stent restenosis (ISR) of bare-metal stents (BMS) and drug-eluting stents (DES). Here, we evaluated the components of neointimal tissue using integrated backscatter intravascular ultrasound (IB-IVUS) and focused on the time course after stent implantation and tissue signal distribution. We evaluated 125 lesions of 125 patients who underwent target lesion revascularization for ISR (BMS: n = 73, DES: n = 52). Volume analysis of a 4-mm length centered on a minimum lumen area in every 1-mm cross-sectional area was performed...
April 17, 2019: Heart and Vessels
Yipin Zhao, Jiaojiao Yang, Yingying Ji, Shunli Wang, Tong Wang, Fengyun Wang, Jianmin Tang
No-reflow is one of the major complications of primary percutaneous coronary artery intervention (pPCI) in the treatment of acute ST-segment elevation myocardial infarction (STEMI). Fibrinogen-to-albumin ratio (FAR) has currently emerged as a novel inflammatory marker to predict inflammation in chronic diseases. This study aimed to investigate whether admission FAR values predicts angiographic no-reflow and short-term prognosis in all STEMI patients. A total of 510 consecutive STEMI patients who underwent successful pPCI between September 2016 and May 2018 were included in this study...
April 16, 2019: Heart and Vessels
Koki Shishido, Futoshi Yamanaka, Tomoki Ochiai, Tsuyoshi Yamabe, Kenichiro Noguchi, Takashi Ota, Yasuhiro Koide, Hidemitsu Ogino, Yutaka Tanaka, Shigeru Saito
Transcatheter aortic valve implantation (TAVI) is a viable treatment option for high-risk patients with severe aortic stenosis. In Japan, TAVI can be performed using first-generation self-expandable Medtronic CoreValve or balloon-expandable Edwards SAPIEN-XT from 2012. Since the durability and hemodynamic outcomes after transcatheter heart valve (THV) implantation in Japanese patients have not been clearly elucidated, we assessed serial changes in post-TAVI THV performances over a-3-year period by transthoracic echocardiography (TTE)...
April 16, 2019: Heart and Vessels
Hiroki Teragawa, Chikage Oshita, Tomohiro Ueda
It is well known that patients with gastroesophageal reflux disease (GERD) experience GERD-related chest pain, but little is known about the relationship between GERD and coronary artery disease (CAD). We evaluated medical history of GERD in patients with suspected CAD and its association with types of CAD. We enrolled 236 patients who underwent coronary angiography (CAG). We assessed past medical history of each patient, making note of esophageal or stomach diseases such as GERD including reflux esophagitis and non-erosive reflux disease...
April 16, 2019: Heart and Vessels
Miho Mitsui, Akihisa Kataoka, Yugo Nara, Fukuko Nagura, Hideyuki Kawashima, Hirofumi Hioki, Makoto Nakashima, Yusuke Watanabe, Naoyuki Yokoyama, Ken Kozuma
Conventional diuretic therapy for low-flow (LF) severe aortic stenosis (SAS) often has an inadequate effect or causes hemodynamic instability. Tolvaptan is used for acute heart failure in addition to conventional diuretics, and it does not cause intravascular dehydration. This study aimed to retrospectively investigate the safety and efficacy of tolvaptan in the acute phase in 56 consecutive patients with SAS and compared LF-SAS with normal-flow (NF) SAS. The primary endpoints were adverse clinical events (death, worsening heart failure, worsening renal failure, fatal arrhythmia, cardiogenic or hypovolemic shock, and use of inotropic agents) and the volume of urine within 48 h of tolvaptan administration...
April 16, 2019: Heart and Vessels
Naoki Hayakawa, Satoshi Kodera, Noriyoshi Ohki, Junji Kanda
This study was performed to evaluate the efficacy and safety of endovascular therapy (EVT) by diluted contrast digital subtraction angiography (DSA) in patients with chronic kidney disease (CKD). Patients with peripheral artery disease (PAD) often have CKD; thus, EVT carries a risk of contrast-induced nephropathy (CIN). Reducing the amount of contrast medium is, therefore, important in these patients. We developed a novel EVT method using DSA with diluted contrast medium. DSA parameters were adjusted for diluted contrast angiography (1:10 dilution), and we defined this technique as low-concentration DSA (LC-DSA)...
April 15, 2019: Heart and Vessels
Hiroya Takafuji, Shinobu Hosokawa, Riyo Ogura, Yoshikazu Hiasa
In the original publication of the article, the below sentence were garbled.
April 15, 2019: Heart and Vessels
Shunsuke Matsumoto, Shigeo Okuda, Yoshitake Yamada, Tatsuya Suzuki, Akihiro Tanimoto, Atsushi Nozaki, Masahiro Jinzaki
Myocardial T1 mapping is clinically valuable for assessing the myocardium, and modified look-locker inversion-recovery (MOLLI) approaches have been commonly used for measuring myocardial T1 values. To date, several other sequences have been developed for measuring myocardial T1 values, and saturation-recovery-based sequences have been shown to be less dependent on various factors, such as T2 times and magnetization transfer, than inversion-recovery techniques. Systematic differences in T1 values between different sequences have been reported; therefore, definition of the normal range of native T1 values is required before clinical usage can begin...
April 11, 2019: Heart and Vessels
Nobuhiro Murata, Takafumi Hiro, Tadateru Takayama, Suguru Migita, Tomoyuki Morikawa, Takehiro Tamaki, Takashi Mineki, Keisuke Kojima, Naotaka Akutsu, Mitsumasa Sudo, Daisuke Kitano, Daisuke Fukamachi, Atsushi Hirayama, Yasuo Okumura
Low wall shear stress (WSS) is associated with plaque formation. However, the relationship between WSS and coronary plaque vulnerability remains unclear. Therefore, this study aimed to clarify the in vivo relationship between luminal WSS derived from three-dimensional (3D) computed tomography (CT) and plaque vulnerability within the coronary artery. Forty-three consecutive patients with ischemic heart disease and coronary stenotic lesions were enrolled and underwent coronary angiography and color-coded intravascular ultrasonography (iMap™) followed by multi-slice coronary CT angiography...
April 11, 2019: Heart and Vessels
Akio Chikata, Takeshi Kato, Kazuo Usuda, Shuhei Fujita, Michiro Maruyama, Kan-Ichi Otowa, Shin-Ichiro Takashima, Hisayoshi Murai, Soichiro Usui, Hiroshi Furusho, Shuichi Kaneko, Masayuki Takamura
Phrenic nerve (PN) stimulation is essential for the elimination of PN palsy during balloon-based pulmonary vein isolation (PVI). Although ultrasound-guided vascular access is safe, insertion of a PN stimulation catheter via central venous access carries a potential risk of the development of mechanical complications. We evaluated the safety of a left cubital vein approach for positioning a 20-electrode atrial cardioversion (BeeAT) catheter in the coronary sinus (CS), and the feasibility of right PN pacing from the superior vena cava (SVC) using proximal electrodes of the BeeAT catheter...
April 10, 2019: Heart and Vessels
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