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International Journal of Technology Assessment in Health Care

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https://read.qxmd.com/read/30957730/addressing-health-system-values-in-health-technology-assessment-the-use-of-evidence-informed-deliberative-processes
#1
Wija Oortwijn, Philip Klein
Health technology assessment (HTA) is increasingly used around the globe to inform resource allocation decisions. Furthermore, the importance of using explicit and transparent criteria for coverage decision making in line with health system values has been acknowledged. However, the values of a health system are often not explicitly taken into account in the HTA process. This situation influences the allocation of scarce resources and could lead to a discord between the HTA outcome and the values of the health system...
April 8, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30922418/assessing-data-sources-for-medicine-price-studies
#2
Sabine Vogler, Peter Schneider
OBJECTIVES: There is no established methodology to assess the feasibility of medicine price data sources. Against this backdrop, a framework to guide the selection of most appropriate price data sources for pharmacoeconomic research has been developed. METHODS: A targeted literature review was carried out. Dimensions discussed in literature as relevant for medicine price comparisons and practical experience of the authors in medicine price studies informed the conceptional work of the framework development...
March 29, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30919794/methods-assessing-sociocultural-aspects-of-health-technologies-results-of-a-literature-review
#3
Anne Kathrin Stich, Kati Mozygemba, Kristin Bakke Lysdahl, Lisa Maria Pfadenhauer, Bjørn Hofmann, Gert-Jan van der Wilt, Ansgar Gerhardus
OBJECTIVES: Social and cultural aspects are rarely assessed in health technology assessments (HTA), despite being part of most HTA definitions. One hypothesis for the reason why they are hardly considered in HTA is that we lack relevant assessment methods. Accordingly, this review aims at providing an overview of methodological approaches to address social and cultural aspects related to health technologies in HTA. METHODS: We conducted a comprehensive literature search by searching fourteen databases and a hand-search of two pertinent journals...
March 28, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30894242/exploring-the-application-of-cost-effectiveness-evaluation-in-the-japanese-national-health-insurance-system
#4
Hisayuki Ogura, Shigekazu Komoto, Takeru Shiroiwa, Takashi Fukuda
OBJECTIVES: Advances in health care due to the development and introduction of new drugs and medical devices have brought considerable benefits to people and patients in terms of upgraded quality of life and extended years of survival. However, some are concerned that the very advancement of health care would increase further the inflation of national healthcare costs. In response to these concerns, Japan's Central Social Insurance Medical Council ("Chuikyo") began in 2012 to examine how cost-effectiveness evaluation might be applied to the national health insurance system, and has been working toward establishing a system for its usage...
March 21, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30871648/cost-effectiveness-of-pain-management-strategies-in-advanced-cancer
#5
David M Meads, John L O'Dwyer, Claire T Hulme, Rocio Rodriguez Lopez, Michael I Bennett
OBJECTIVES: Uncontrolled pain in advanced cancer is a common problem and has significant impact on individuals' quality of life and use of healthcare resources. Interventions to help manage pain at the end of life are available, but there is limited economic evidence to support their wider implementation. We conducted a case study economic evaluation of two pain self-management interventions (PainCheck and Tackling Cancer Pain Toolkit [TCPT]) compared with usual care. METHODS: We generated a decision-analytic model to facilitate the evaluation...
March 15, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30867077/toward-a-strategy-to-involve-patients-in-health-technology-assessment-in-spain
#6
Ana Toledo-Chávarri, Yolanda Alvarez-Perez, Yolanda Triñanes, Lilisbeth Perestelo-Pérez, Mireia Espallargues, Matilde Palma, Pedro Serrano-Aguilar
OBJECTIVES: The aim of this study was to develop a feasible and effective strategy to involve patients in the Spanish Network of Agencies of Health Technology Assessment (RedETS). METHODS: The framework for patient involvement (PI) in the assessment activities and processes of RedETS were developed through a research project that included: (i) a systematic search of the international literature describing a strategy and/or a methodology linking health technology assessment (HTA) and PI; (ii) a qualitative study through interviews with RedETS members to analyze the perceptions of PI among HTA managers in the Spanish context; (iii) a Delphi consultation with three large platforms of patients, carers and consumer organizations in Spain about their perspectives of PI; (iv) a consensus process with the members of the RedETS Governing Council to define the final strategy...
March 14, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30864531/health-technology-assessment-in-malaysia-past-present-and-future
#7
Sarimin Roza, Sabirin Junainah, Mudla Mohamed Ghazali Izzuna, Ku Abdul Rahim Ku Nurhasni, Mohd Aminuddin Mohd Yusof, Md Darus Noormah, Md Fuzi Syful Azlie, Lee Sit Wai
OBJECTIVES: The aim of this study was to provide a comprehensive overview of the evolution of health technology assessment (HTA) in Malaysia over the past decade. METHODS: We described the evolution of HTA program in Malaysia based on review of administrative data, publicly available information and quantitative description of impact evaluation. RESULTS: Health Technology Assessment HTA was formalized in Malaysia in 1995 as a central structure within the Ministry of Health, Malaysia in 1995...
March 13, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30854989/cost-effectiveness-analysis-of-sunitinib-versus-interferon-alfa-for-first-line-treatment-of-advanced-and-or-metastatic-renal-cell-carcinoma-in-singapore
#8
Sil-Ling Pruis, Mohamed Ismail Abdul Aziz, Fiona Pearce, Min Han Tan, David Bin-Chia Wu, Kwong Ng
OBJECTIVES: This study was conducted to evaluate the cost-effectiveness of sunitinib versus interferon-alfa for the treatment of advanced and/or metastatic renal cell carcinoma (RCC) in Singapore. METHODS: A partitioned survival model with three health states (progression-free, progressive disease, and death) was developed from a healthcare payer perspective over a 10-year time horizon. Survival curves from the pivotal trial of sunitinib versus interferon-alfa were extrapolated beyond the trial period to estimate the underlying progression-free survival and overall survival parametric distributions...
March 11, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30829566/is-stratification-testing-for-treatment-of-chronic-obstructive-pulmonary-disease-exacerbations-cost-effective-in-primary-care-an-early-cost-utility-analysis
#9
Lucy Abel, Helen A Dakin, Nia Roberts, Helen F Ashdown, Chris C Butler, Gail Hayward, Ann Van den Bruel, Philip J Turner, Yaling Yang
OBJECTIVES: Patients with chronic obstructive pulmonary disease (COPD) who experience acute exacerbations usually require treatment with oral steroids or antibiotics, depending on the etiology of the exacerbation. Current management is based on clinician's assessment and judgement, which lacks diagnostic accuracy and results in overtreatment. A test to guide these decisions in primary care is in development. We developed an early decision model to evaluate the cost-effectiveness of this treatment stratification test in the primary care setting in the United Kingdom...
March 4, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30829189/hospital-based-health-technology-assessment-in-kazakhstan-3-years-experience-of-one-unit
#10
Andrey Avdeyev, Adlet Tabarov, Amir Akhetov, Nasrulla Shanazarov, David Hailey, Aygul Kaptagayeva, Liazzat Zhanabekova, Aliya Gizatullina, Larissa Makalkina
OBJECTIVES: The aim of this study was to describe the development and activities of the Hospital-Based Health Technology Assessment (HB-HTA) Unit in the Hospital of the President's Affairs Administration, one of the first examples of the implementation of HB-HTA into the practice of Kazakhstani hospitals. METHODS: Details of the development of the Unit were obtained from the hospital's administrative records. The Unit's own records were used to describe the reports prepared and the clinical areas that were covered...
March 4, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30819270/hurdle-poisson-regression-model-for-identifying-factors-related-to-noncompliance-and-waiting-time-for-confirmatory-diagnosis-in-colorectal-cancer-screening
#11
Hsiao-Hsuan Jen, Tsung-Hsi Wang, Han-Mo Chiu, Szu-Min Peng, Chen-Yang Hsu, Sherry Yueh-Hsia Chiu, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Yi-Chia Lee, Hsiu-Hsi Chen, Jean Ching-Yuan Fann
OBJECTIVES: Population-based colorectal cancer (CRC) screening programs that use a fecal immunochemical test (FIT) are often faced with a noncompliance issue and its subsequent waiting time (WT) for those FIT positives complying with confirmatory diagnosis. We aimed to identify factors associated with both of the correlated problems in the same model. METHODS: A total of 294,469 subjects, either with positive FIT test results or having a family history, collected from 2004 to 2013 were enrolled for analysis...
March 1, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30813983/adaptive-evolution-in-rapid-assessments-a-25-year-perspective
#12
Paula Corabian, Bing Guo, Carmen Moga, N Ann Scott
OBJECTIVES: This article retrospectively examines the evolution of rapid assessments (RAs) produced by the Health Technology Assessment (HTA) Program at the Institute of Health Economics over its 25-year relationship with a single requester, the Alberta Health Ministry (AHM). METHODS: The number, types, and methodological attributes of RAs produced over the past 25 years were reviewed. The reasons for developmental changes in RA processes and products over time were charted to document the push-pull tension between AHM needs and the HTA Program's drive to meet those needs while responding to changing methodological benchmarks...
February 28, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30813980/outcomes-and-impacts-of-10-year-hta-implementation-in-taiwan
#13
Kai-Ling Kao, Li-Ying Huang, Yen-Hui Wu, Churn-Shiouh Gau
OBJECTIVES: In 2007, Taiwan began conducting health technology assessments (HTA) to support the National Health Insurance Administration (NHIA) in its reimbursement decisions for drugs, medical devices, and medical services. METHODS: In this study, the development, missions, and procedures of the implementation of HTA in Taiwan are briefly introduced. Moreover, the value of HTA is examined by reviewing the outcomes and impacts of recent HTA-related research projects, which are classified into five categories: (i) pharmaceutical products, (ii) medical procedures, (iii) medical devices, (iv) health policy, and (v) social care...
February 28, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30789111/timely-consistent-transparent-assessment-of-market-access-evidence-implementing-tools-based-on-the-hta-core-model%C3%A2-in-a-pharmaceutical-company
#14
Pierre Ducournau, Cornelia Irl, Iain Tatt, Mary McCarvil, Marlene Gyldmark
OBJECTIVES: Evidence requirements and assessment methods access differ between health technology assessment (HTA) agencies. The HTA Core Model® provides a standardized approach to HTA, targeting evidence sharing and collaboration between participating HTA bodies. It is fit for purpose from an industry perspective and was used by pharmaceutical company Roche to develop a framework for internal assessment of evidence required for market access and coverage/reimbursement ("access evidence")...
February 21, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30744730/quality-assessment-of-reporting-of-economic-evaluation-in-cardiac-sugery-has-it-improved
#15
Pascale Guerre, Nermine Laaboub, Cyrille Colin, Jean-François Obadia, Christell Julien, Abdelbaste Hrifach, Hugo Rabier, Hassan Serrier, Daniel Grinberg
OBJECTIVES: Cardiac surgery has seen substantial scientific progress over recent decades. Health economic evaluations have become important tools for decision makers to prioritize scarce health resources. The present study aimed to identify and critically appraise the reporting quality of health economic evaluations conducted in the field of cardiac surgery. METHODS: A literature search was performed to identify health economic evaluations in cardiac surgery. The consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement was used to assess the quality of reporting of studies...
February 12, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30744713/nudging-in-neonatology-practical-wisdom-and-accountability-for-reasonableness
#16
Michal Stanak
OBJECTIVES: The way choice is presented has an impact on decision-making. This is the case also in the context of neonatal intensive care units (NICUs), particularly in the challenging cases that concern the limit of viability. The objective of this article is to examine the role of nudging in the shared decision-making in neonatology and elaborate on the respective moral challenges. RESULTS: Nudging is not morally neutral. There are two key sources of ethical issues at the heart of nudging...
February 12, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30744712/early-assessment-of-innovation-in-a-healthcare-setting
#17
Linn Nathalie Støme, Tron Moger, Kristian Kidholm, Kari J Kværner
OBJECTIVES: Early assessment can assist in allocating resources for innovation effectively and produce the most beneficial technology for an institution. The aim of the present study was to identify methods and discuss the analytical approaches applied for the early assessment of innovation in a healthcare setting. METHODS: Knowledge synthesis based on a structured search (using the MEDLINE, Embase, and Cochrane databases) and thematic analysis was conducted. An analytical framework based on the stage of innovation (developmental, introduction, or early diffusion) was applied to assess whether methods vary according to stage...
February 12, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30732667/how-procurement-judges-the-value-of-medical-technologies-a-review-of-healthcare-tenders
#18
Fiona A Miller, Pascale Lehoux, Stuart Peacock, Valeria E Rac, Jeff Neukomm, Carolyn Barg, Jessica P Bytautas, Murray Krahn
OBJECTIVES: Procurement's important role in healthcare decision making has encouraged criticism and calls for greater collaboration with health technology assessment (HTA), and necessitates detailed analysis of how procurement approaches the decision task. METHODS: We reviewed tender documents that solicit medical technologies for patient care in Canada, focusing on request for proposal (RFP) tenders that assess quality and cost, supplemented by a census of all tender types...
February 8, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30730288/patient-involvement-in-reflective-multicriteria-decision-analysis-to-assist-decision-making-in-oncology
#19
Xavier Badia, Alfonso Aguarón, Ana Fernández, Antonia Gimón, Begoña Nafria, Bernard Gaspar, Laura Guarga, María Gálvez, Marta Fuentes, Noelia Paco, Roberto Saldaña
OBJECTIVES: Patient involvement in drug evaluation decision making is increasing. The aim of the current study was to develop a multi-criteria decision analysis (MCDA) framework that would enable the inclusion of the patient perspective in the selection of appropriate criteria for MCDAs being used in the value assessments of oncologic drugs. METHODS: A literature review was conducted to identify and define criteria used in drug assessments from patient perspectives...
February 7, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/30722803/rheumatoid-arthritis-treated-with-6-months-of-first-line-biologic-or-biosimilar-therapy-an-updated-systematic-review-and-network-meta-analysis
#20
Emma L Simpson, Shijie Ren, Emma S Hock, John W Stevens, Aymeric Binard, Yves-Marie Pers, Rachel Archer, Suzy Paisley, Matthew D Stevenson, Chloé Herpin, Salah Ghabri
OBJECTIVES: The aim of this study was to estimate the effectiveness of first-line biologic disease modifying drugs(boDMARDs), and their approved biosimilars (bsDMARDs), compared with conventional (csDMARD) treatment, in terms of ACR (American College of Rheumatology) and EULAR (European League against Rheumatism) responses. METHODS: Systematic literature search, on eight databases to January 2017, sought ACR and EULAR data from randomized controlled trials (RCTs) of boDMARDs / bsDMARDs (in combination with csDMARDs, or monotherapy)...
February 6, 2019: International Journal of Technology Assessment in Health Care
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