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International Journal of Technology Assessment in Health Care

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https://read.qxmd.com/read/31296277/commentary-in-praise-of-studies-that-use-more-than-one-generic-preference-based-measure
#1
David Feeny, William Furlong, George W Torrance
Objectives and BackgroundGeneric preference-based (GPB) measures of health-related quality of life (HRQL) are widely used as outcome measures in cost-effectiveness and cost-utility analyses (CEA, CUA). Health technology assessment agencies favor GPB measures because they facilitate comparisons among conditions and because the scoring functions for these measures are based on community preferences. However, there is no gold standard HRQL measure, scores generated by GPB measures may differ importantly, and changes in scores may fail to detect important changes in HRQL...
July 12, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31292015/context-specific-economic-evaluation-for-molecular-pathology-tests-an-application-in-colorectal-cancer-in-the-west-of-scotland
#2
Janet Bouttell, Yun Yi Tan, David Creed, Gillian McGaffin, Neil Hawkins, Ruth McLaughlin, Graeme Smith, Paul Westwood, Nicola Williams, Janet Graham
OBJECTIVES: The cost-effectiveness of molecular pathology testing is highly context dependent. The field is fast-moving, and national health technology assessment may not be relevant or timely for local decision makers. This study illustrates a method of context-specific economic evaluation that can be carried out in a limited timescale without extensive resources. METHODS: We established a multi-disciplinary group including an oncologist, pathologists and a health economist...
July 11, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31292014/heated-humidified-high-flow-nasal-cannula-for-preterm-infants-an-updated-systematic-review-and-meta-analysis
#3
Nigel Fleeman, Yenal Dundar, Prakesh S Shah, Ben Nj Shaw
BACKGROUND: Heated humidified high-flow nasal cannula (HHHFNC) is gaining popularity as a mode of respiratory support. We updated a systematic review and meta-analyses examining the efficacy and safety of HHHFNC compared with standard treatments for preterm infants. The primary outcome was the need for reintubation for preterm infants following mechanical ventilation (post-extubation analysis) or need for intubation for preterm infants not previously intubated (analysis of primary respiratory support) METHODS: We searched PubMed, MEDLINE, Embase, and the Cochrane Library for randomized controlled trials (RCTs) of HHHFNC versus standard treatments...
July 11, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31292013/leaving-no-one-behind-participatory-technology-appraisal-as-a-platform-for-agenda-setting-to-address-disparities-in-access-to-health-services-in-thailand
#4
Sripen Tantivess, Suradech Doungthipsirikul
OBJECTIVES: This article discusses how participatory technology appraisal as part of the Universal Coverage Scheme (UCS) in Thailand contributes to improving access to essential health services among vulnerable populations. METHODS: Document review was conducted on health technology appraisal approaches introduced by the UCS. The review involves health benefit proposals advanced by stakeholders and also meeting minutes of relevant working groups and committees published between 2010 and 2015...
July 11, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31262373/interaction-between-objective-performance-measures-and-subjective-user-perceptions-in-the-evaluation-of-medical-devices-a-case-study-addendum
#5
Matthew D Haydock, Anubhav Mittal, Carissa F Wilkes, David H Lim, Elizabeth Broadbent, John A Windsor
No abstract text is available yet for this article.
July 2, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31250778/ethical-challenges-related-to-patient-involvement-in-health-technology-assessment
#6
Meredith Vanstone, Julia Abelson, Julia Bidonde, Kenneth Bond, Raquel Burgess, Carolyn Canfield, Lisa Schwartz, Laura Tripp
Including information and values from patients in HTA has the potential to improve both the process and outcomes of health technology policy decisions. Accordingly, funding and structural incentives to include patients in HTA activities have increased over the past several years. Unfortunately, these incentives have not yet been accompanied by a corresponding increase in resources, time, or commitment to responsiveness. In this Perspectives piece, we reflect on our collective experiences participating in, conducting, and overseeing patient engagement activities within HTA to highlight the ethical challenges associated with this area of activity...
June 28, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31218976/delayed-patient-access-to-innovative-medical-technologies-in-south-korea-a-lead-time-analysis-of-reimbursement-coverage-determinations
#7
Sang-Soo Lee, Jae-Eun Myung, Liesl Strachan
Background and ObjectivesTimely access to innovative medical technologies driven by accelerated patient access pathways can substantially improve the health outcomes of patients who often have few therapeutic alternatives. We analyzed lead-times for the medical procedure reimbursement coverage process undertaken in South Korea from 2014 to 2017, which is considered one of the most important factors contributing to delays in patient access to new medical technologies. METHODS: This analysis was performed using the open datasets source of "Medical Procedure Expert Evaluation Committee (MPEEC)" meeting results and medical procedure coverage application information published on the Health Insurance Review and Assessment Service Web site...
June 20, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31198129/how-to-deal-with-the-inevitable-generating-real-world-data-and-using-real-world-evidence-for-hta-purposes-from-theory-to-action
#8
Wija Oortwijn, Laura Sampietro-Colom, Rebecca Trowman
OBJECTIVES: Real-world evidence (RWE), derived from real-world data (RWD), is already used, to some extent, for health technology assessment (HTA) purposes. With the increased availability of RWD, there is potential for more widespread use but also challenges ensuring reliable RWE for HTA. Opportunities to overcome key challenges, identified at a scoping meeting, were discussed during the 2019 HTA international (HTAi) Global Policy Forum (GPF). METHODS: Reflection of discussions using Design Thinking (an interactive process aimed to solve complex problems) between seventy-three representatives from not-for-profit, for-profit organizations, and HTAi leadership...
June 14, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31190671/population-adjustment-methods-for-indirect-comparisons-a-review-of-national-institute-for-health-and-care-excellence-technology-appraisals
#9
David M Phillippo, Sofia Dias, Ahmed Elsada, A E Ades, Nicky J Welton
OBJECTIVES: Indirect comparisons via a common comparator (anchored comparisons) are commonly used in health technology assessment. However, common comparators may not be available, or the comparison may be biased due to differences in effect modifiers between the included studies. Recently proposed population adjustment methods aim to adjust for differences between study populations in the situation where individual patient data are available from at least one study, but not all studies...
June 13, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31190670/health-technology-assessment-in-thailand-institutionalization-and-contribution-to-healthcare-decision-making-review-of-literature
#10
Pattara Leelahavarong, Suradech Doungthipsirikul, Suthasinee Kumluang, Akanittha Poonchai, Nitichen Kittiratchakool, Danai Chinnacom, Netnapis Suchonwanich, Sripen Tantivess
OBJECTIVES: To explore health technology assessment (HTA) in Thailand focusing on its institutionalization, key elements for HTA introduction, and HTA contribution to policy. METHODS: A review of literature covered a wide range of topics, including the institutionalization of HTA, elements of HTA introduction, and the role of HTA in policy decision making in Thai context. Additional information from the authors' involvement in the policy decision-making process in Thailand was also considered...
June 13, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31133089/use-of-real-world-data-sources-for-canadian-drug-pricing-and-reimbursement-decisions-stakeholder-views-and-lessons-for-other-countries
#11
Don Husereau, Edward Nason, Tarun Ahuja, Enkeleida Nikaï, Eva Tsakonas, Philip Jacobs
BACKGROUND: Canada has a long history of the use of clinical evidence to support healthcare decision making. Given improvements in data holdings and analytic capacity in Canada and stakeholder interest, the purpose of this study is to reflect on perceptions of the value of real-world evidence in pricing and reimbursement decisions, barriers to its optimal use in pricing and reimbursement, current initiatives that may lead to its increased use, and what role the pharmaceutical industry may play in this...
May 28, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31131776/cost-effectiveness-analysis-of-non-invasive-prenatal-testing-for-down-syndrome-in-china
#12
Yan Xu, Yan Wei, Jian Ming, Na Li, Ningze Xu, Raymond W Pong, Yingyao Chen
OBJECTIVES: There is little evidence in China regarding the cost-effectiveness of non-invasive prenatal testing (NIPT) for Down syndrome (DS). This study aims to evaluate the cost-effectiveness of NIPT and provide evidence to inform decision-making. METHODS: To determine the cost-effectiveness of NIPT for DS, a decision-analytic model was developed using the TreeAge Pro software from a societal perspective in a simulated cohort of 10 000 pregnant women. Main indicators were based on field surveys from sampled hospitals in four locations in China and a literature review...
May 27, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31122306/pd50-helping-innovators-navigate-policy-and-regulatory-processes-corrigendum
#13
Maggie MacNeil, Melissa Koch, Don Juzwishin, Paul Stolee
No abstract text is available yet for this article.
May 24, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31122302/improving-access-to-high-cost-technologies-in-the-asia-region
#14
Linda Mundy, Rebecca Trowman, Brendon Kearney
OBJECTIVES: Discussions at the Health Technology Assessment International (HTAi) Asia Policy Forum (HAPF) aimed to understand the meaning of "high-cost technologies," and to explore mechanisms to increase access to these technologies in publicly funded health systems in the Asia region. METHODS: Discussions and presentations at the 2018 HAPF, informed by a literature review and a premeeting survey of HTA agencies and industry, form the basis of this paper...
May 24, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31097044/from-design-to-evaluation-applications-of-health-technology-assessment-in-myanmar-and-lessons-for-low-or-lower-middle-income-countries
#15
Saudamini Vishwanath Dabak, Yot Teerawattananon, Thiri Win
OBJECTIVES: Health technology assessment (HTA) has been widely used to inform coverage decisions in high-income countries over the past few decades and has been getting increasing attention in middle-income countries as a tool for healthcare decision making in recent years. This study aims to use the case of the Maternal and Child Health Voucher Scheme (MCHVS) in Myanmar to understand how HTA can have a policy impact in a low or lower middle-income country. METHODS: The stages heuristic framework was used to describe the policy-making process...
May 17, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31064563/incorporating-household-spillovers-in-cost-utility-analysis-a-case-study-using-behavior-change-in-copd
#16
Arjun Bhadhuri, Hareth Al-Janabi, Sue Jowett, Kate Jolly
OBJECTIVES: It is important to capture all health effects of interventions in cost-utility analyses conducted under a societal or healthcare perspective. However, this is rarely done. Household spillovers (health effects on patients' other household members) may be particularly likely in the context of technologies and interventions to change behaviors that are interdependent in the household. Our objective was to prospectively collect outcome data from household members and illustrate how these can be included in a cost-utility analysis of a behavior change intervention in chronic obstructive pulmonary disease (COPD)...
May 8, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31044688/patient-preferences-concerning-alternative-treatments-for-neuroendocrine-tumors-results-of-the-piano-study
#17
Axel C Mühlbacher, Christin Juhnke
OBJECTIVES: Neuroendocrine tumors (NETs) are rare, slow-growing malignant tumors. So far, there are no data on patient preferences regarding its therapy. This empirical study aimed to elicit patient preferences in the drug treatment of NET. METHODS: Based on qualitative patient interviews and an analytic hierarchy process, six patient-relevant attributes were analyzed and weighted using a discrete-choice experiment. Patients were recruited with the help of a NET support group...
May 2, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31023393/proposition-of-a-shared-and-value-oriented-work-structure-for-hospital-based-health-technology-assessment-and-enterprise-risk-management-processes
#18
Ana Paula Beck da Silva Etges, Veronique Grenon, Elaine Aparecida Felix, Joana Siqueira de Souza, Francisco José Kliemann Neto, Carisi Anne Polanczyk
BACKGROUND: Healthcare organizations have invested efforts on hospital-based health technology assessment (HB-HTA) and enterprise risk management (ERM) processes for novel systems to obtain more accurate data on which to base strategic decisions. This study proposes to analyze how HB-HTA and ERM processes can share personal resources and skills to achieve principles with value-oriented results. METHODS: Literature on ERM and HB-HTA and data from interviews with healthcare managers compose the research data sources, which were submitted to a qualitative data analysis...
April 26, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31017075/a-framework-for-aiding-the-translation-of-scientific-evidence-into-policy-the-experience-of-a-hospital-based-technology-assessment-unit
#19
Nisha D Almeida, Lorraine Mines, Ioana Nicolau, Alison Sinclair, David Felipe Forero, James M Brophy, Nancy Mayo, Nandini Dendukuri
OBJECTIVES: Very few practical frameworks exist to guide the formulation of recommendations at hospital-based health technology assessment (HTA) units. The objectives of our study were: (i) to identify decision criteria specific to the context of hospital-based health technologies and interventions, (ii) to estimate the extent to which the expert community agrees on the importance of the identified criteria, (iii) to incorporate the identified criteria into a decision-aid tool, and (iv) to illustrate the application of a prototype decision-aid tool...
April 24, 2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31006412/the-spanish-network-of-agencies-for-health-technology-assessment-and-services-of-the-national-health-system-redets
#20
Pedro Serrano-Aguilar, José Asua-Batarrita, María Teresa Molina-López, Mireia Espallargues, Joan Pons-Rafols, Sandra García-Armesto, Paloma Arriola-Bolado, Marisa López-García, María José Faraldo-Vallés, Luis María Sánchez-Gómez, Celia Juárez-Rojo, Isabel Prieto-Yerro, Paloma Casado-Durández, Antonio Sarria-Santamera
Earlier activities on health technology assessment (HTA) started in Spain around 1984, with the creation of a National Advisory Board on HTA, and the development of national and regional HTA organizations in the early 1990s. In 2012, the Spanish Health Ministry established the Spanish Network for Health Technology Assessment of the National Health System (RedETS); funded at national level and including all public HTA organizations at national and regional levels. RedETSis focused on the assessment of nondrug health technologies to inform the revision (approval and funding or disinvestment) of the Benefit Portfolio of the Spanish NHS...
April 22, 2019: International Journal of Technology Assessment in Health Care
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