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European Journal of Epidemiology

Arvid Sjölander, Stijn Vansteelandt
Multiple tests arise frequently in epidemiologic research. However, the issue of multiplicity adjustment is surrounded by confusion and controversy, and there is no uniform agreement on whether or when adjustment is warranted. In this paper we compare frequentist and Bayesian frameworks for multiple testing. We argue that the frequentist framework leads to logical difficulties, and is unable to distinguish between relevant and irrelevant multiplicity adjustments. We further argue that these logical difficulties resolve within the Bayesian framework, and that the Bayesian framework makes a clear and coherent distinction between relevant and irrelevant adjustments...
May 13, 2019: European Journal of Epidemiology
Susanne Strohmaier, Elizabeth E Devore, Celine Vetter, A Heather Eliassen, Bernard Rosner, Olivia I Okereke, Eva S Schernhammer
We investigated the relationship between maternal history of nightshift work before and shift work during pregnancy and offspring risk of depression and anxiety, among mothers participating in the Nurses Health Study II and in their offspring enrolled in the Growing Up Today Study 2 between 2004 and 2013. Case definitions were based on offspring self-reports of physician/clinician-diagnosed depression and/or anxiety, regular antidepressant use and depressive symptoms assessed using the Center for Epidemiologic Studies Depression Scale...
May 13, 2019: European Journal of Epidemiology
Florence Gignac, Dora Romaguera, Silvia Fernández-Barrés, Claire Phillipat, Raquel Garcia Esteban, Mónica López-Vicente, Jesus Vioque, Ana Fernández-Somoano, Adonina Tardón, Carmen Iñiguez, Maria-Jose Lopez-Espinosa, Manoli García de la Hera, Pilar Amiano, Jesús Ibarluzea, Mònica Guxens, Jordi Sunyer, Jordi Julvez
There is scientific evidence on the protective effects of nut intake against cognitive decline in the elderly; however, this effect has been less explored in child neurodevelopment and no studies have explored the potential longitudinal association with nut intake during pregnancy. We aimed to analyze the association of maternal nut intake during pregnancy with child neuropsychological outcomes. We included 2208 mother-child pairs from a population-based birth cohort in four regions of Spain. The follow up settings were during pregnancy (first and third trimesters), birth, 1...
May 7, 2019: European Journal of Epidemiology
Youngyo Kim, Youjin Je, Edward Giovannucci
Coffee consumption has been associated with decreased mortality in previous studies. As aging, obesity, and lifestyle factors affect the risk of mortality, the association between coffee and mortality needs to be examined in various subpopulations by characteristics of subjects. To quantitatively assess this association, we conducted an updated meta-analysis including stratified analyses by potential modifiers. We searched in the PubMed and Web of Science databases through March 8, 2019, and conducted meta-analysis including linear and non-linear dose-response analyses...
May 4, 2019: European Journal of Epidemiology
Karl Mårild, German Tapia, Øivind Midttun, Per M Ueland, Maria C Magnus, Marian Rewers, Lars C Stene, Ketil Størdal
Ecological observations suggest an inverse relationship between smoking in pregnancy and celiac disease (CD) in offspring. While individual-level analyses have been inconsistent, they have mostly lacked statistical power or refined assessments of exposure. To examine the association between pregnancy-related smoking and CD in the offspring, as well as its consistency across data sets, we analyzed: (1) The Norwegian Mother and Child Cohort (MoBa) of 94,019 children, followed from birth (2000-2009) through 2016, with 1035 developing CD; (2) a subsample from MoBa (381 with CD and 529 controls) with biomarkers; and (3) a register-based cohort of 536,861 Norwegian children, followed from birth (2004-2012) through 2014, with 1919 developing CD...
April 29, 2019: European Journal of Epidemiology
Lukas Schwingshackl, Sven Knüppel, Nathalie Michels, Carolina Schwedhelm, Georg Hoffmann, Khalid Iqbal, Stefaan De Henauw, Heiner Boeing, Brecht Devleesschauwer
Our aim was to estimate and rank 12 food groups according to disability-adjusted life years (DALYs) from coronary heart disease (CHD), stroke, type 2 diabetes (T2D), and colorectal cancer (CRC) in 16 European countries. De novo published non-linear dose-response meta-analyses of prospective studies (based on 297 primary reports), and food consumption data from the European Food Safety Authority Comprehensive European Food Consumption Database in Exposure Assessment, and DALY estimates from the Institute for Health Metrics and Evaluation were used...
April 27, 2019: European Journal of Epidemiology
Seolhye Kim, Yoosoo Chang, Young Rae Lee, Hyun-Suk Jung, Young Youl Hyun, Kyu-Beck Lee, Kwan Joong Joo, Kyung Eun Yun, Hocheol Shin, Seungho Ryu
The renal outcome of solitary kidney remains controversial. We examined the longitudinal association of congenital or acquired solitary kidney with the development of chronic kidney disease (CKD). A cohort study was performed involving 271,171 Korean men and women free of CKD at baseline who underwent a health screening program and who were followed annually or biennially for an average of 5.4 years. Solitary kidney was determined based on ultrasonographic findings. CKD was defined as an estimated glomerular filtration rate of < 60 ml/min/1...
April 25, 2019: European Journal of Epidemiology
Congying Xia, Mieneke Rook, Gert Jan Pelgrim, Grigory Sidorenkov, Hendrik J Wisselink, Jurjen N van Bolhuis, Peter M A van Ooijen, Jiapan Guo, Matthijs Oudkerk, Harry Groen, Maarten van den Berge, Pim van der Harst, Hildebrand Dijkstra, Marleen Vonder, Marjolein A Heuvelmans, Monique D Dorrius, Peter Paul De Deyn, Geertruida H de Bock, Aafje Dotinga, Rozemarijn Vliegenthart
Lung cancer, chronic obstructive pulmonary disease (COPD), and coronary artery disease (CAD) are expected to cause most deaths by 2050. State-of-the-art computed tomography (CT) allows early detection of lung cancer and simultaneous evaluation of imaging biomarkers for the early stages of COPD, based on pulmonary density and bronchial wall thickness, and of CAD, based on the coronary artery calcium score (CACS), at low radiation dose. To determine cut-off values for positive tests for elevated risk and presence of disease is one of the major tasks before considering implementation of CT screening in a general population...
April 23, 2019: European Journal of Epidemiology
Reem Waziry, Luuk Gras, Sanaz Sedaghat, Henning Tiemeier, Gerrit J Weverling, Mohsen Ghanbari, Jaco Klap, Frank de Wolf, Albert Hofman, M Arfan Ikram, Jaap Goudsmit
Chronological age alone is not a sufficient measure of the true physiological state of the body. The aims of the present study were to: (1) quantify biological age based on a physiological biomarker composite model; (2) and evaluate its association with death and age-related disease onset in the setting of an elderly population. Using structural equation modeling we computed biological age for 1699 individuals recruited from the first and second waves of the Rotterdam study. The algorithm included nine physiological parameters (c-reactive protein, creatinine, albumin, total cholesterol, cytomegalovirus optical density, urea nitrogen, alkaline phosphatase, forced expiratory volume and systolic blood pressure)...
April 13, 2019: European Journal of Epidemiology
Noel S Weiss
No abstract text is available yet for this article.
April 11, 2019: European Journal of Epidemiology
Nathalie Auger, Laura Arbour, Wei Luo, Ga Eun Lee, Marianne Bilodeau-Bertrand, Tom Kosatsky
Causes of birth defects are unclear, and the association with electromagnetic fields is inconclusive. We assessed the relationship between residential proximity to extremely low frequency electromagnetic fields from power grids and risk of birth defects. We analyzed a population-based sample of 2,164,246 infants born in Quebec, Canada between 1989 and 2016. We geocoded the maternal residential postal code at delivery and computed the distance to the nearest high voltage electrical transmission line or transformer station...
April 11, 2019: European Journal of Epidemiology
Clair A Enthoven, Jan Willem Lodewijk Tideman, Jan Roelof Polling, Milly S Tedja, Hein Raat, Adriana I Iglesias, Virginie J M Verhoeven, Caroline C W Klaver
Myopia is a refractive error of the eye caused by a complex interplay between nature and nurture. The aim of this study was to investigate whether environmental risk factors can influence the genetic effect in children developing myopia. A total of 3422 children participating in the birth-cohort study Generation R underwent an extensive eye examination at 9 years with measurements of refractive error and axial length corneal radius ratio (AL/CR). Environmental risk factors were evaluated using a questionnaire, and environmental risk scores (ERS) were calculated using backward regression analyses...
April 3, 2019: European Journal of Epidemiology
Anna-Janina Stephan, Ralf Strobl, Lars Schwettmann, Christa Meisinger, Karl-Heinz Ladwig, Birgit Linkohr, Barbara Thorand, Annette Peters, Eva Grill
Morbidity trends may result from cohort experiences in critical developmental age. Our objective was to compare the health status of 65-71 year-olds who were in critical developmental age before (1937-June 1945), during (June 1945-June 1948) and after (June 1948-1950) the early reconstruction and food crisis (ERFC) period in Germany following World War II. Data originate from the KORA (Cooperative Health Research in the Region of Augsburg)-Age study in Southern Germany. We used the 2008 baseline sample born 1937-1943 and the 2015 enrichment sample born 1944-1950...
April 2, 2019: European Journal of Epidemiology
Jonas F Ludvigsson, Pia Svedberg, Ola Olén, Gustaf Bruze, Martin Neovius
Education, income, and occupation are factors known to affect health and disease. In this review we describe the Swedish Longitudinal Integrated Database for Health Insurance and Labour Market Studies (LISA, Longitudinell Integrationsdatabas för Sjukförsäkrings- och Arbetsmarknadsstudier). LISA covers the adult Swedish population aged ≥ 16 years registered on December 31 each year since 1990 (since 2010 individuals aged ≥ 15 years). The database was launched in response to rising levels of sick leave in the country...
March 30, 2019: European Journal of Epidemiology
Elsa Kobeissi, Makoto Hibino, Han Pan, Dagfinn Aune
Abdominal aortic aneurysms (AAA) are fatal in 80% of the cases when ruptured. Hypertension has been considered a potential risk factor for AAA; but the findings from prospective cohort studies have not been entirely consistent, nor have they been summarised in a comprehensive meta-analysis. Our aim was to conduct a systematic review and meta-analysis of cohort studies of the association between blood pressure, hypertension and AAA to clarify the strength and shape of these associations. We searched PubMed and Embase databases for relevant cohort studies up to April 30th, 2018...
March 22, 2019: European Journal of Epidemiology
Sanne Verhoog, Pedro Marques-Vidal, Oscar H Franco
No abstract text is available yet for this article.
March 21, 2019: European Journal of Epidemiology
Adela Castelló, Marcelo Urquia, María Ángeles Rodríguez-Arenas, Francisco Bolúmar
Deliveries from Indian and Chinese mothers present a higher than expected male:female ratio in their own countries, in northern Europe, EEUU and Canada. No studies have been carried out in southern European countries. We explored whether the high male-to-female ratio common in Indian and Chinese communities, also exists among families from those regions who live in Spain. For that purpose we designed a cross-sectional population-based study containing data on 3,133,908 singleton live births registered in the Spanish Vital Statistics Registry during the period 2007-2015...
March 20, 2019: European Journal of Epidemiology
Brian K Lee, Raz Gross, Richard W Francis, Håkan Karlsson, Diana E Schendel, Andre Sourander, Abraham Reichenberg, Erik T Parner, Mady Hornig, Amit Yaniv, Helen Leonard, Sven Sandin
Season of birth has been hypothesized to be a risk factor for autism spectrum disorder (ASD). However, the evidence has been mixed and limited due to methodological challenges. We examine ASD birth trends for 5,464,628 births across 5 countries. ASD birth prevalence data were obtained from the International Collaboration for Autism Registry Epidemiology database, including children born in Denmark, Finland, Norway, Sweden, and Western Australia. Empirical mode decomposition and cosinor modeling were used to assess seasonality...
March 20, 2019: European Journal of Epidemiology
Olaf M Dekkers
No abstract text is available yet for this article.
March 18, 2019: European Journal of Epidemiology
Christel M Middeldorp, Janine F Felix, Anubha Mahajan, Mark I McCarthy
The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established...
March 18, 2019: European Journal of Epidemiology
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