Maha Houssen, Rasha El-Mahdy, Nouran E Samra, Yousra Tera, Kamel Nayera Mostafa, Manal M El-Desoky, Fatma Azzahraa Hisham, Asem A Hewidy, Rehab A Elmorsey, Hala Samaha, Rasha Mahmoud, Mona S Abdelhafez
AIM: To evaluate the serum levels of HMGB1, IL1β, and α-klotho in COVID-19 patients with different disease severity, investigate their association with clinicopathological parameters, and to assess HMGB1 rs1045411 polymorphism and its relation with clinical severity. METHODS: 120 COVID-19 patients (89 critically ill, 15 severe, and 16 moderately severe) along with 80 healthy control were enrolled.The serum levels of HMGB1,IL1β, and α-klotho were determined by ELISA...
February 6, 2024: Immunological Investigations