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European Journal of Surgical Oncology

https://read.qxmd.com/read/38870875/preoperative-and-postoperative-mri-based-models-versus-clinical-staging-systems-for-predicting-early-recurrence-in-hepatocellular-carcinoma
#1
JOURNAL ARTICLE
Ye Lu, Huanhuan Wang, Chenxia Li, Ferdos Faghihkhorasani, Cheng Guo, Xin Zheng, Tao Song, Qingguang Liu, Shaoshan Han
BACKGROUND: To predict the early recurrence of HCC patients who received radical resection using preoperative variables based on Gd-EOB-DTPA enhanced MRI, followed by the comparison with the postoperative model and clinical staging systems. METHODS: One hundred and twenty-nine HCC patients who received radical resection were categorized into the early recurrence group (n = 48) and the early recurrence-free group (n = 81). Through COX regression analysis, statistically significant variables of laboratory, pathologic, and Gd-EOB-DTPA enhanced MRI results were identified...
June 8, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870872/the-impact-of-laterality-on-the-incidence-and-prognosis-of-epithelial-ovarian-cancer
#2
JOURNAL ARTICLE
Yang Zhang, Chuling Wu, Yucong Huang, Jihui Kang, Shuzhong Yao, Ye Chen, Langyu Gu, Guofen Yang
INTRODUCTION: Epithelial ovarian cancer (EOC) is the most prevalent type of ovarian cancer, yet the impact of ovarian laterality has received limited attention. MATERIALS AND METHODS: We conducted a comprehensive investigation into the impact of laterality (left-right and bilateral-unilateral) on EOC incidence and prognosis, focusing on distinct subtypes. Binomial tests and Pearson's χ2 tests were employed to compare occurrence rates among laterality groups...
June 8, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870870/letter-to-the-editor-staging-laparoscopy-with-peritoneal-lavage-to-identify-peritoneal-metastases-and-free-intraperitoneal-cancer-cells-in-the-management-of-locally-advanced-gastric-cancer
#3
LETTER
https://read.qxmd.com/read/38870876/oncologic-outcomes-of-de-escalating-axillary-treatment-in-clinically-node-positive-breast-cancer-patients-treated-with-neoadjuvant-systemic-therapy-a-two-center-cohort-study
#4
JOURNAL ARTICLE
Robert-Jan Schipper, Anne de Bruijn, Maurice J C van der Sangen, Johanne G Bloemen, Ingrid van den Hoven, Ester E M Schepers, Birgit E P Vriens, Thom Boerman, Dorien C Rijkaart, Linda M H van de Winkel, Christel Brouwer, Laurence J C van Warmerdam, Maaike P M Gielens, Rob M G van Bommel, Yvonne E van Riet, Adri C Voogd, Grard A P Nieuwenhuijzen
BACKGROUND: The aim of the present study was to report the 5-year axillary recurrence-free interval (aRFI) in clinically node-positive breast cancer patients treated according to a de-escalating axillary treatment protocol after neoadjuvant systemic therapy (NST). METHODS: All patients diagnosed in two hospitals between October 2014 and March 2021 were identified retrospectively. Data on diagnostic workup, treatment and follow-up was collected. Adjuvant axillary treatment was considered based on the initial staging using 18F-FDG PET/CT and the results of axillary lymph node marking with a radioactive-iodine seed protocol or a targeted axillary dissection procedure...
June 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870874/effect-of-ras-and-braf-mutations-on-peritoneal-metastasis-risk-and-cytoreductive-surgery-hyperthermic-intraperitoneal-chemotherapy-efficacy-in-colorectal-cancer-a-systematic-review-and-meta-analysis
#5
REVIEW
Ziming Gao, Xiang Qi, Ruiying Wang, Zhitong Wen, Hao Qi, Mingguang Ju, Xiaoxu Liu, Junye Wang, Heng Zhou, Zhi Zhu, Xiaofang Liu, Kai Li
BACKGROUND: Colorectal cancer (CRC) patients with peritoneal metastasis (CRC-PM) have a worse prognosis than those with liver and lung metastases. Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is an effective locoregional treatment for CRC-PM. To date, the prognostic analysis of CRS/HIPEC mostly focuses on clinical and pathological characteristics; however, genetic characteristics, such as RAS/BRAF mutation status, are not sufficient. This study aimed to systematically assess the correlation between RAS/BRAF status and PM risk, as well as the prognostic efficacy of CRS/HIPEC for CRC...
June 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870873/electrochemotherapy-ect-in-treatment-of-mucosal-head-and-neck-tumors-an-international-network-for-sharing-practices-on-ect-inspect-study-group-report
#6
JOURNAL ARTICLE
Giulia Bertino, Marta Minuti, Ales Groselj, Crt Jamsek, Barbara Silvestri, Silvia Carpene, Paolo Matteucci, Giuseppe Riva, Giancarlo Pecorari, Matteo Mascherini, Camilla Kjær Lønkvist, Tobian Muir, Christian Kunte, Francesca de Terlizzi, Gregor Sersa
The aim of this multicenter study was to evaluate the effectiveness and safety of electrochemotherapy (ECT) for the treatment of mucosal tumors in the head and neck. A total of 71 patients with 84 nodules of different histologies in the oral cavity, pharynx and larynx treated by ECT were evaluated. The data were collected from the InspECT database from 10 participating centers throughout Europe. Primary and recurrent/secondary tumors of different histologies were treated. The overall response rate was 65 %, with a 33 % complete response rate with limited side effects...
June 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870871/three-year-follow-up-results-of-radiofrequency-ablation-for-low-risk-papillary-thyroid-microcarcinomas-systematic-review-and-meta-analysis
#7
REVIEW
Xidong Xu, Ying Peng, Guoxin Han
OBJECTIVES: Confidence in long-term treatment results of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) is required in comparison with surgery and active surveillance (AS). The objective of this meta-analysis is to report more than three years of follow-up results of radiofrequency ablation for PTMCs. METHODS: Ovid PUBMED, COCHRANE, and EMBASE databases were searched through Nov 19, 2023, for studies reporting outcomes in patients with PTMC treated with radiofrequency ablation and followed up for more than 3 years...
June 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38865930/feasibility-of-remote-access-and-minimally-invasive-video-assisted-approaches-in-lateral-neck-dissection-for-papillary-thyroid-carcinoma-a-systematic-review-and-network-meta-analysis
#8
REVIEW
Van Cuong Nguyen, Chang Myeon Song, Yong Bae Ji, Jae Kyung Myung, Jeong Seon Park, Kyung Tae
BACKGROUND: This study was conducted to evaluate the feasibility and surgical outcomes of minimally invasive video-assisted thyroidectomy (MIVAT) and three remote-access approaches, namely the robotic bilateral axillo-breast approach (BABA-R), endoscopic breast-chest approach (BCA-E), and robotic gasless transaxillary approach (GTAA-R) in lateral neck dissection for papillary thyroid carcinoma, compared with conventional transcervical approach (CTA). METHODS: The literature search was conducted in the PubMed, EMBASE, and Cochrane Library databases, covering the period January 2000 to February 2024...
June 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38870869/surgical-outcomes-and-prognosis-of-her2-invasive-breast-cancer-patients-with-a-dcis-component-treated-with-breast-conserving-surgery-after-neoadjuvant-systemic-therapy
#9
JOURNAL ARTICLE
Roxanne A W Ploumen, Eva L Claassens, Loes F S Kooreman, Kristien B M I Keymeulen, Maartje A C E van Kats, Sander M J van Kuijk, Sabine Siesling, Thiemo J A van Nijnatten, Marjolein L Smidt
INTRODUCTION: In up to 72 % of HER2+ invasive breast cancer (IBC), a ductal carcinoma in situ (DCIS) component is present. The presence of DCIS is associated with increased positive surgical margins after breast-conserving surgery (BCS). The aim of this study was to assess surgical margins, recurrence and survival in a nationwide cohort of HER2+ IBC with versus without a DCIS component, treated with neoadjuvant systemic therapy (NST) and BCS. MATERIALS AND METHODS: Women diagnosed with HER2+ IBC treated with NST and BCS, between 2010 and 2019, were selected from the Netherlands Cancer Registry and linked to the Dutch Nationwide Pathology Databank...
June 4, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38865931/partial-nephrectomy-after-a-period-of-active-surveillance-are-perioperative-and-pathology-outcomes-worsened-compared-to-immediate-surgery
#10
JOURNAL ARTICLE
Riccardo Bertolo, Alessandro Veccia, Francesca Montanaro, Francesco Artoni, Alberto Baielli, Michele Boldini, Francesco Ditonno, Sonia Costantino, Vincenzo De Marco, Filippo Migliorini, Antonio Benito Porcaro, Riccardo Rizzetto, Maria Angela Cerruto, Alessandro Antonelli
INTRODUCTION: Active surveillance (AS) is a viable strategy for managing small renal masses (SRMs) in lieu of immediate surgery, but concerns persist regarding its impact on delayed partial nephrectomy (PN) outcomes. We aimed to compare perioperative and pathological outcomes of patients initially on AS for SRMs, later undergoing PN, against those undergoing immediate PN. MATERIALS AND METHODS: Data were extracted from a prospective institutional database (January 2018-September 2023) for patients with cT1a renal masses...
June 4, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38843660/a-nomogram-based-on-pretreatment-radiomics-and-dosiomics-features-for-predicting-overall-survival-associated-with-esophageal-squamous-cell-cancer
#11
JOURNAL ARTICLE
Daisuke Kawahara, Riku Nishioka, Yuji Murakami, Yuki Emoto, Kazuma Iwashita, Ryohei Sasaki
OBJECTIVES: To propose a nomogram-based survival prediction model for esophageal squamous cell carcinoma (ESCC) treated with definitive chemoradiotherapy using pretreatment computed tomography (CT), positron emission tomography (PET) radiomics and dosiomics features, and common clinical factors. METHODS: Radiomics and dosiomics features were extracted from CT and PET images and dose distribution from 2 institutions. The least absolute shrinkage and selection operator (LASSO) with logistic regression was used to select radiomics and dosiomics features by calculating the radiomics and dosiomics scores (Rad-score and Dos-score), respectively, in the training model...
June 4, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38851136/perineural-invasion-an-independent-risk-factor-for-cervical-cancer-prognosis-and-a-possible-pathway-for-a-future-targeted-treatment
#12
LETTER
Christos Iavazzo, Helen J Trihia, Ioannis D Gkegkes
No abstract text is available yet for this article.
June 1, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38824815/lymph-node-metastasis-burden-identifies-head-and-neck-squamous-cell-carcinoma-patients-benefiting-from-adjuvant-chemoradiation-a-propensity-score-matching
#13
JOURNAL ARTICLE
Peng Li, Qigen Fang, Junhui Yuan, Ruihua Luo
INTRODUCTION: To examine the influence of adjuvant chemoradiation therapy (CRT) on survival, stratified by varying numbers and level involved of metastatic lymph nodes in patients with head and neck squamous cell carcinoma (HNSCC). METHODS: Patients who underwent surgery for metastatic, negative margin HNSCC without extranodal extension were retrospectively enrolled and divided into two groups based on adjuvant therapy received: radiotherapy (RT) and CRT. The impact of RT versus CRT, stratified by the number of positive lymph nodes and the level involved, on Disease-Free Survival (DFS) and Overall Survival (OS) was analyzed...
May 31, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38843661/prognostic-characteristics-recurrence-patterns-and-survival-outcomes-of-vulval-squamous-cell-carcinoma-a-twelve-year-retrospective-analysis-of-a-tertiary-centre
#14
JOURNAL ARTICLE
Ahmed Darwish, Lamiese Ismail, Sanjiv Manek, Karin Hellner, Sean Kehoe, Hooman Soleymani Majd
INTRODUCTION: Vulval cancer is a rare gynaecological malignancy. In this study, we present a tertiary centre case analysis to examine the recurrence patterns and survival outcomes of vulval squamous cell carcinoma (SCC). METHODS: This is a retrospective cohort study of women who received treatment at Oxford University Hospitals between February 2010 and July 2022 for primary vulval SCC. RESULTS: We included 98 cases. The median age at diagnosis was 68 years...
May 29, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38825402/reply-to-surgery-vs-non-surgery-for-liver-metastases-from-primary-breast-cancer
#15
LETTER
Mark Yeo Hao Xuan, Yoshio Masuda
No abstract text is available yet for this article.
May 29, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38851937/surgery-vs-non-surgery-for-liver-metastases-from-primary-breast-cancer
#16
LETTER
Wei Han, Chun-Tao Shi, Hao-Nan Wang
No abstract text is available yet for this article.
May 28, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38824816/tumor-inflammatory-microenvironment-contribution-to-survival-in-resected-upstaged-adenocarcinomas
#17
JOURNAL ARTICLE
Alessandro Bonis, Vincenzo Verzeletti, Francesca Lunardi, Luigi Lione, Giorgio Cannone, Eleonora Faccioli, Marco Mammana, Samuele Nicotra, Fiorella Calabrese, Andrea Dell'Amore, Federico Rea
INTRODUCTION: Tumor Inflammatory microenvironment (TIME) encompasses several immune pathways modulating cancer development and escape that are not entirely uncoded. The results achieved with immunotherapy elicited the scientific debate on TIME also in non-small cell lung cancer (NSCLC). We aimed to investigate whether TIME (in terms of PD-L1 expression and/or Tumor Infiltrating Lymphocytes - TILs) played a separate role in terms of survival (OS) in resected upstaged lung adenocarcinomas (ADCs), excluding other perioperative variables as confounders...
May 28, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38823377/-shaping-gastric-cancer-outcomes-advancing-diagnosis-and-treatment-through-staging-laparoscopy-in-peritoneal-metastasis-detection
#18
LETTER
Mustafa Mansoor, Muhammad Ahmed, Ibrahim Manzoor
No abstract text is available yet for this article.
May 28, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38816257/improving-machine-learning-predictions-for-metastases-in-colorectal-cancer
#19
LETTER
Ali Azlan, Zoha Rafaqat, Abraiz Ahmad
No abstract text is available yet for this article.
May 25, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38815335/the-oncologic-burden-of-residual-disease-in-incidental-gallbladder-cancer-an-elastic-net-regression-model-to-profile-high-risk-features
#20
JOURNAL ARTICLE
Rebecca Marino, Francesca Ratti, Andrea Casadei-Gardini, Margherita Rimini, Federica Pedica, Lucrezia Clocchiatti, Luca Aldrighetti
INTRODUCTION: Incidental Gallbladder Cancer (IGBC) following cholecystectomy constitutes a significant portion of gallbladder cancer diagnoses. Re-exploration is advocated to optimize disease clearance and enhance survival rates. The consistent association of residual disease (RD) with inferior oncologic outcomes prompts a critical examination of re-resection's role as a modifying factor in the natural history of IGBC. METHODS: All patients diagnosed with gallbladder cancer between 2012 and 2022 were included...
May 25, 2024: European Journal of Surgical Oncology
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