Noa Ofir, Yuval Mizrakli, Yariv Greenshpan, Yftach Gepner, Omri Sharabi, Gal Tsaban, Hila Zellicha, Anat Yaskolka Meir, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Yoash Chassidim, Assaf Rudich, Anat Reiner-Benaim, Iris Shai, Ilan Shelef, Roi Gazit
BACKGROUND: Increased levels of bone marrow adipose tissue (BMAT) are negatively associated with skeletal health and hematopoiesis. BMAT is known to increase with age; however, the effect of long-term weight loss on BMAT is still unknown. OBJECTIVE: In this study, we examined BMAT response to lifestyle-induced weight loss in 138 participants (mean age 48 y; mean body mass index 31 kg/m2 ), who participated in the CENTRAL-MRI trial. METHODS: Participants were randomized for dietary intervention of low-fat or low-carb, with or without physical activity...
March 8, 2023: Bone