journal
https://read.qxmd.com/read/38768643/necrotizing-enterocolitis-associated-acute-kidney-injury-transforming-the-paradigm
#1
JOURNAL ARTICLE
Padma Parvesh Garg, Jeffrey Shenberger, Andrew Micheal South, Parvesh Mohan Garg
Necrotizing enterocolitis (NEC) is one of the most common conditions requiring emergency surgery in the neonatal intensive care unit and is associated with a septic shock-like state contributing to multi-organ dysfunction. NEC affects 6-10% of very-low birth-weight infants and remains a leading cause of death. The occurrence of severe AKI following surgical NEC is a harbinger of multiple morbidities. This review presents current evidence about the clinical impact of NEC associated AKI on the clinical outcomes...
May 20, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38768642/factors-associated-with-refractory-severe-hypertension-in-patients-with-preeclampsia
#2
JOURNAL ARTICLE
Kari Flicker, Danielle Long, Maya Vishnia, Madeleine Wright, Matilda Francis, Kenyone Shevon King, Lauren Gilgannon, Neha Gupta, Aref Rastegar, Sive Rohini, Lea Nehme, George Saade, Baha M Sibai, Tetsuya Kawakita
OBJECTIVE: To identify factors associated with refractory severe hypertension that does not resolve after an initial dose of antihypertensive medication in patients with preeclampsia. STUDY DESIGN: This was a retrospective study of all pregnant and postpartum individuals with a diagnosis of preeclampsia, superimposed preeclampsia, HELLP (hemolysis, elevated liver enzymes, low platelet) syndrome, or eclampsia who delivered at 22 weeks or greater at a single academic institution from 2010 to 2020...
May 20, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38754462/association-between-gestational-age-and-perinatal-outcomes-in-women-with-late-preterm-premature-rupture-of-membranes
#3
JOURNAL ARTICLE
Eleanor M Schmidt, Jacqueline M Powell, Bharti Garg, Aaron B Caughey
OBJECTIVE: ACOG suggests expectant management until 34 weeks for patients with PPROM. New data suggests extending to 37 weeks might enhance neonatal outcomes, reducing prematurity-linked issues. This study aims to assess adverse neonatal outcomes across gestational ages in women with PPROM. STUDY DESIGN: A retrospective cohort study was performed using linked vital statistics and ICD-9 data. Gestational age at delivery ranged from 32 to 36 weeks. Outcomes include NICU admission >24 hours, neonatal sepsis, respiratory distress syndrome, necrotizing enterocolitis, intraventricular hemorrhage, and neonatal death...
May 16, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38754461/neonatologist-at-the-well-child-clinic-a-high-risk-infant-follow-up-pilot-study
#4
JOURNAL ARTICLE
Stephen Marcus Reingold, Liora Yotvat, M Schimmel
Objective High-risk infant follow-up (HRIF) is a complex process lacking standardization. We present a simple, single-provider model that proves effective and is well received by caregivers. Study Design In this study we measured caregiver use and satisfaction with high-risk infant follow-up visit attended by an experienced neonatologist in a well-care setting, soon after discharge. Results One hundred parents participated in the survey. 78% of infants were seen in the first 3 months of life and 39% within one month of discharge...
May 16, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38749483/scholarly-activity-during-neonatal-perinatal-medicine-fellowship
#5
JOURNAL ARTICLE
Nicolle Fernandez Dyess, Patrick Myers, Christiane Dammann, Patricia Chess, Erika Abramson, Caroline Andy, Pnina Weiss
Objective To describe scholarly activity training during neonatal-perinatal medicine (NPM) fellowship and factors associated with scholarship productivity. Study Design NPM fellowship program directors (FPD) were surveyed between March and October 2019, as part of a larger study of all pediatric subspecialty programs, to define barriers, resources, and productivity for fellow scholarly activity. High productivity was defined as > 75% of fellows in a program in the last 5 years having a manuscript accepted for publication based on fellowship scholarly work...
May 15, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38744421/the-impact-of-telehealth-on-obstetrical-outcomes-during-the-covid-19-pandemic
#6
JOURNAL ARTICLE
Alexander Saucedo, Mamaram Ceesay, Sanjana Ravi, Kelsey Mumford, Miriam Alvarez, Jeny Gharty, Lorie M Harper, Alison G Cahill
BACKGROUND: Nationwide, obstetric clinics modified prenatal care to include telehealth visits in response to the COVID-19 pandemic, enabling the opportunity to investigate its impact on patient outcomes. We hypothesized that use of prenatal telehealth visits would increase the number of prenatal visits, decrease the frequency of urgent triage/emergency department (ED) visits, and improve perinatal outcomes. OBJECTIVE: To determine the impact of telehealth on number of obstetric prenatal visits and urgent triage/ED visits amidst the COVID-19 pandemic...
May 14, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38744322/prevalence-and-outcomes-of-gastrointestinal-anomalies-in-down-syndrome
#7
JOURNAL ARTICLE
Marwa M Elgendy, Josef Cortez, Firas Saker, Mohamed A Mohamed, Hany Aly
OBJECTIVES:  Our objective was to investigate the prevalence of small intestinal atresia and Hirschsprung's disease (HD) in infants with Down syndrome (DS) and its impact on outcomes. STUDY DESIGN:  We analyzed the National Inpatient Sample dataset. We included infants with DS, small intestinal atresia, HD, and the concomitant occurrence of both conditions. Regression analysis was used to control clinical and demographic variables. RESULTS:  A total of 66,213,034 infants were included, of whom, 99,861 (0...
May 14, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38740366/critical-organ-dysfunction-and-preoperative-mortality-in-newborns-with-hypoplastic-left-heart-syndrome
#8
JOURNAL ARTICLE
Matthew D Durbin, James L Wynn, Paulomi Chaudhry, Alyx Posorske, Ellen Voskoboynik, Woo Y Park, Orlyn Lavilla, Khyzer B Aziz
Hypoplastic left heart syndrome (HLHS) is fatal without surgical intervention. An important subset of HLHS patients die prior to surgical intervention, but this population is underevaluated. The neonatal sequential organ failure assessment score (nSOFA) is an operational definition of organ dysfunction that can identify those with a high risk of mortality among neonatal intensive care unit (NICU) patients. The utility of the nSOFA to predict preoperative mortality in the unique HLHS population is unknown and could inform care, particularly care provided by neonatology staff...
May 13, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38729183/placental-sars-cov-2-infection-and-its-implications-for-increased-risk-of-adverse-pregnancy-outcomes
#9
JOURNAL ARTICLE
Bingbing Wang, Wei-Bin Shen, Courtney Townsel, Lauren Baracco, James Logue, E Albert Reece, Matthew B Frieman, Peixin Yang
INTRODUCTION: Pregnant women are at increased risk of COVID-19. This could be explained through the prism of physiologic and immunologic changes in pregnancy. In addition, certain immunological reactions originate in the placenta in response to viral infections. OBJECTIVE: This study aimed to investigate whether SARS-CoV-2 can infect the human placenta and discuss its implications in the pathogenesis of adverse pregnancy outcomes. STUDY DESIGN: We conducted a retrospective cohort study in which we collected placental specimens from pregnant women who had a laboratory-confirmed SARS-CoV-2 infection...
May 10, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38729164/prediction-of-covid-19-severity-at-delivery-after-asymptomatic-or-mild-covid-19-during-pregnancy
#10
JOURNAL ARTICLE
Grecio J Sandoval, Torri D Metz, William A Grobman, Tracy A Manuck, Brenna L Hughes, George R Saade, Monica Longo, Hyagriv N Simhan, Dwight J Rouse, Hector Mendez-Figueroa, Cynthia Gyamfi-Bannerman, Angela C Ranzini, Maged M Costantine, Harish M Sehdev, Alan T N Tita
OBJECTIVE:  This study aimed to develop a prediction model that estimates the probability that a pregnant person who has had asymptomatic or mild coronavirus disease 2019 (COVID-19) prior to delivery admission will progress in severity to moderate, severe, or critical COVID-19. STUDY DESIGN:  This was a secondary analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients who delivered from March through December 2020 at hospitals across the United States...
May 10, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38729163/treatment-for-neonatal-abstinence-syndrome-using-nonpharmacological-interventions
#11
JOURNAL ARTICLE
Tonya W Robinson, Reetta Stikes, Jaki Sorrell, Amanda Gater, Adam T Booth, Amanda Gardner, Colleen Greenwell, Shannon Businger, Ryan Low, Rachael Petrie
OBJECTIVE:  Management of neonatal abstinence syndrome includes nonpharmacological interventions, but their effectiveness may not be verified before implemented. The objective of this study is to evaluate the effectiveness of a type of bassinet in the treatment of infants with neonatal abstinence syndrome. STUDY DESIGN:  This is a retrospective observational cohort study. Study setting involved a 24-bed open-bay Level III neonatal intensive care unit located in a metropolitan academic trauma facility...
May 10, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38723640/antenatal-breast-milk-expression-survey-of-individuals-whose-pregnancy-was-complicated-by-diabetes-exploring-knowledge-perceptions-experiences-and-milk-volume-expressed
#12
JOURNAL ARTICLE
Sarah Mess, Anna Palatnik, Erwin Cabacungan
OBJECTIVE:  Antenatal breast milk expression (ABE) offers a host of benefits, including reduced formula consumption, support for breastfeeding success, and increased maternal satisfaction. Despite these advantages, experience with ABE differs significantly, often leading to anxiety over perceived inadequate milk supply and eventual breastfeeding cessation. This study comprehensively evaluates the knowledge, attitudes, and real-world experiences of individuals with gestational or pregestational diabetes concerning ABE, with a focus on total milk volume expressed prior to birth...
May 9, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38714206/is-the-risk-of-intrahepatic-cholestasis-increased-with-supplemental-progesterone
#13
JOURNAL ARTICLE
Matthew C H Rohn, Lindsey Vignali, Isabel Reeder, Kiana Khosravian, Scott Petersen
OBJECTIVE:  This study aimed to evaluate the relationship between supplemental progesterone use during pregnancy and the development of intrahepatic cholestasis of pregnancy (ICP). STUDY DESIGN:  A retrospective, matched case-control study was conducted among a population of women who delivered at George Washington University Hospital (GW) between 2012 and 2022. Women diagnosed with ICP (cases) were identified using International Statistical Classification of Diseases (ICD) codes, and data were collected via chart abstraction...
May 7, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38714205/therapeutic-hypothermia-for-neonatal-hypoxic-ischemic-encephalopathy-reducing-variability-in-practice-through-a-collaborative-telemedicine-initiative
#14
JOURNAL ARTICLE
Danieli M K Leandro, Gabriel F T Variane, Alex Dahlen, Rafaela F R Pietrobom, Jessica A R R de Castro, Daniela P Rodrigues, Mauricio Magalhães, Marcelo J Mimica, Krisa P Van Meurs, Valerie Y Chock
OBJECTIVE:  This study aimed to assess the viability of implementing a tele-educational training program in neurocritical care for newborns diagnosed with hypoxic-ischemic encephalopathy (HIE) and treated with therapeutic hypothermia (TH), with the goal of reducing practice variation. STUDY DESIGN:  Prospective study including newborns with HIE treated with TH from 12 neonatal intensive care units in Brazil conducted from February 2021 to February 2022...
May 7, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38714204/management-utilization-and-outcomes-of-preterm-labor-in-an-integrated-health-care-system
#15
JOURNAL ARTICLE
Darios Getahun, David A Sacks, Jiaxiao Shi, Fagen Xie, Nehaa Khadka, Vicki Y Chiu, Nana A Mensah, Chantal C Avila, Meiyu Yeh, Aniket A Kawatkar, Michael S Ruma, Derek Joyce, Michael J Fassett
OBJECTIVE:  Fetal fibronectin (fFN) testing and transvaginal ultrasound (TVUS) are diagnostic tools used to predict impending spontaneous preterm birth (sPTB) among women presenting with preterm labor (PTL). We evaluated the association between fFN testing or TVUS cervical length (CL) measurement in predicting sPTB, respiratory distress syndrome (RDS), neonatal intensive care unit (NICU) admission, and sPTB-related costs. STUDY DESIGN:  We conducted a retrospective cohort study using data from the Kaiser Permanente Southern California electronic health system (January 1, 2009-December 31, 2020) using diagnostic and procedure codes, along with a natural language processing algorithm to identify pregnancies with PTL evaluations...
May 7, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38701858/associations-between-parental-engagement-in-the-neonatal-intensive-care-unit-and-neighborhood-level-socioeconomic-status
#16
JOURNAL ARTICLE
Lisa Strouss Wallace, Ololade Okito, Kelsi Mellin, Lamia Soghier
OBJECTIVES: 1) To determine the effect of neighborhood-level socioeconomic status (SES), which considers the social and physical environment where a person lives, on parental engagement in the Neonatal Intensive Care Unit (NICU); 2) To compare the relationships between parental engagement and individual versus neighborhood-level measures of SES. STUDY DESIGN: In this cohort study, parents (n=45) of premature neonates ≤ 34 weeks gestation were assessed at two and six weeks after birth from December 2017 to October 2019...
May 3, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38698598/erratum-maternal-hemodynamics-from-preconception-to-delivery-research-and-potential-diagnostic-and-therapeutic-implications-position-statement-by-italian-association-of-pre-eclampsia-and-italian-society-of-perinatal-medicine
#17
JOURNAL ARTICLE
Barbara Vasapollo, Sara Zullino, Gian Paolo Novelli, Daniele Farsetti, Serena Ottanelli, Sara Clemenza, Massimo Micaglio, Enrico Ferrazzi, Daniela Denis Di Martino, Tullio Ghi, Elvira Di Pasquo, Rossana Orabona, Paola Corbella, Maria Grazia Frigo, Federico Prefumo, Tamara Stampalija, Stefano Raffaele Giannubilo, Herbert Valensise, Federico Mecacci
No abstract text is available yet for this article.
May 2, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38698597/cerclage-plus-adjuvant-vaginal-progesterone-for-preterm-birth-prevention-in-patients-with-a-short-or-dilated-cervix-without-prior-preterm-birth
#18
JOURNAL ARTICLE
Jessica M Hart, Annliz Macharia, Anna M Modest, Katherine M Johnson, Julianne Lauring, Erica Nicasio, Michele R Hacker, Melissa H Spiel
OBJECTIVE:  The primary objective was to determine if vaginal progesterone following cerclage for cervical length <10 mm or cervical dilation in patients without a history of spontaneous preterm birth (sPTB) decreased the risk of preterm birth at <34 weeks' gestation compared with cerclage alone. Secondary objectives were to determine if vaginal progesterone following cerclage (1) decreased the risk of preterm birth at <24, <28, and <37 weeks' gestation and (2) increased the latency period from cerclage placement to delivery compared with treatment with cerclage alone...
May 2, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38698596/correlating-severity-of-pulmonary-hypertension-by-echocardiogram-with-mortality-in-premature-infants-with-bronchopulmonary-dysplasia
#19
JOURNAL ARTICLE
Rachel D Torok, Robert A Gardner, Piers C A Barker, Andrew W McCrary, Jennifer S Li, Christoph P Hornik, Matthew M Laughon, Wesley M Jackson
OBJECTIVE:  Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth. Infants with BPD are at increased risk for pulmonary hypertension (PH). Cardiac catheterization is the gold standard for diagnosing PH, but cardiac catheterization is challenging to perform in small, sick, premature infants. The utility of echocardiography for diagnosing PH and predicting outcomes in extremely premature infants has not been clearly defined. Therefore, we sought to use predefined criteria to diagnose PH by echocardiogram and relate PH severity to mortality in extremely premature infants with BPD...
May 2, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38698595/the-impact-on-birth-outcomes-of-sonographic-fetal-weight-estimation-in-neonatal-macrosomia
#20
JOURNAL ARTICLE
Inshirah Sgayer, Karina Nskovica, Iuliia Murkhovskyi, Raneen Abu Shqara, Artyom Bilyk, Lior Lowenstein, Maya Frank Wolf
OBJECTIVE:  Our objective was to examine the association between sonographic estimated fetal weight (EFW) and obstetrical and neonatal outcomes in women with neonatal macrosomia. STUDY DESIGN:  This study, conducted at a tertiary university-affiliated hospital from 2017 to 2021, compared obstetrical and neonatal outcomes between two groups of women who delivered macrosomic newborns (actual birthweight ≥ 4,000 g): (1) those with EFW ≥ 3,800 g (suspected impending macrosomia) and (2) those with EFW < 3,800 g (unsuspected impending macrosomia)...
May 2, 2024: American Journal of Perinatology
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