journal
https://read.qxmd.com/read/38382484/the-use-of-anemia-control-model-is-associated-with-improved-hemoglobin-target-achievement-lower-rates-of-inappropriate-erythropoietin-stimulating-agents-and-severe-anemia-among-dialysis-patients
#1
JOURNAL ARTICLE
Mario Garbelli, Francesco Bellocchio, Maria Eva Baro Salvador, Milena Chermisi, Abraham Rincon Bello, Isabel Berdud Godoy, Sofia Ortego Perez, Kateryna Shkolenko, Alicia Sobrino Perez, Diana Samaniego Toro, Christian Apel, Jovana Petrovic, Stefano Stuard, Carlo Barbieri, Flavio Mari, Luca Neri
INTRODUCTION The Anemia Control Model (ACM) is a certified medical device suggesting the optimal ESA and iron dosage for patients on hemodialysis. We sought to assess the effectiveness and safety of ACM in a large cohort of hemodialysis patients. METHODS This is a retrospective study of dialysis patients treated in Nephrocare centers between 01-06-2013 and 31-12-2019. We compared patients treated according to ACM suggestions and patients treated in clinics where ACM was not activated. We stratified patients belonging to the reference group by historical target achievement rates in their referral centers (tier 1: <70%; tier 2: 70%-80%; tier 3: >80%)...
February 21, 2024: Blood Purification
https://read.qxmd.com/read/38377975/erratum
#2
(no author information available yet)
No abstract text is available yet for this article.
February 20, 2024: Blood Purification
https://read.qxmd.com/read/38377974/fluid-balance-in-continuous-renal-replacement-therapy-prescribing-delivering-and-review
#3
REVIEW
Ian Charles Baldwin, Amy McKaige
BACKGROUND: Historically IV and enteral fluids given during acute kidney injury (AKI) were restricted before the introduction of continuous renal replacement therapies (CRRT) when more liberal fluids improved nutrition for the critically ill. However fluid accumulation can occur when higher volumes each day are not considered in the fluid balance prescribing and daily review for the NET ultrafiltration (NUF) volume target. KEY MESSAGES: The delivered hours of CRRT each day are vital for achievement of fluid balance and time off therapy makes the task more challenging...
February 20, 2024: Blood Purification
https://read.qxmd.com/read/38377967/ultrafiltration-tolerance-a-phenotype-that-we-need-to-recognize
#4
REVIEW
Gonzalo Ramírez-Guerrero, Claudio Ronco
BACKGROUND: The evaluation and management of fluid balance are key challenges in critical care patients who require renal replacement therapies because cumulative fluid balance is an independent factor that increases morbidity and mortality in different clinical scenarios. SUMMARY: One of the strategies when fluid overload is refractory to diuretics, is extracorporeal fluid removal (i.e., net ultrafiltration [UFNET] during kidney replacement therapy). However, problems with UFNET without individualized assessment are cardiovascular events and intradialytic hypotension, events that contribute to decreasing organ perfusion and sympathetic stress...
February 20, 2024: Blood Purification
https://read.qxmd.com/read/38346416/uncomplicated-calcium-citrate-anticoagulation-during-continuous-renal-replacement-therapy-in-two-other-patients-with-metformin-accumulation
#5
LETTER
Beatrice Brunoni, Francesco Zadek, Alessandro Protti, Maurizio Cecconi, Roberto Fumagalli, Thomas Langer
No abstract text is available yet for this article.
February 12, 2024: Blood Purification
https://read.qxmd.com/read/38346415/erratum
#6
(no author information available yet)
No abstract text is available yet for this article.
February 12, 2024: Blood Purification
https://read.qxmd.com/read/38330931/effect-of-hemodialysis-with-medium-cut-off-vs-high-flux-membranes-on-endothelial-function-of-patients-with-chronic-kidney-disease
#7
JOURNAL ARTICLE
Rachel Gatti Armani, Aluizio Barbosa Carvalho, Monique Vercia Rocha E Silva, Renata Verardino, Luiz Bortolotto, Maria Eugenia F Canziani
BACKGROUND: Endothelial dysfunction (ED) is considered a marker of vascular complications, especially in patients with end-stage kidney disease (ESKD). Inflammation and the uremic state contribute to ED in patients undergoing hemodialysis (HD). Recently, the medium cut-off (MCO) dialysis membrane has been proposed to efficiently remove inflammatory cytokines and large middle-sized uremic toxins, with the potential effect to improve endothelial function. This study aims to compare the effect of dialysis with MCO or high-flux membranes on the endothelial function of patients on chronic HD...
February 8, 2024: Blood Purification
https://read.qxmd.com/read/38325347/low-frequency-high-frequency-ratio-is-a-predictor-of-hospitalization-and-death-in-patients-on-maintenance-hemodialysis-a-prospective-study
#8
JOURNAL ARTICLE
Yafei Chen, Xu Li, Li Zhu, Yan Wang, Liangying Gan, Li Zuo
INTRODUCTION: This study aims to evaluate the predictive value of the low frequency/high frequency (LF/HF) ratio in all causes of death and hospitalizations in maintenance hemodialysis (MHD) patients. METHODS: This is a single-center prospective study with a 48-h electrocardiograph (ECG) recording. A total of 110 patients were enrolled in the study from October 1, 2021, to September 30, 2022. ECG recordings started before initiation of the hemodialysis (HD) session and lasted for 48 h, covering the intra- as well as inter- HD period...
February 7, 2024: Blood Purification
https://read.qxmd.com/read/38310867/japanese-study-of-the-effects-of-amg-%C3%AE-1-microglobulin-reduction-rates-on-survival-jamreds-protocol-of-a-multicenter-prospective-observational-cohort-study
#9
JOURNAL ARTICLE
Toshihide Naganuma, Yoshiaki Takemoto, Naohiro Kamada, Daijiro Kabata, Ayumi Shintani, Keiko Ota, Jun Minakuchi, Ken Tsuchiya, Hideki Kawanishi
INTRODUCTION: Recent advances in dialysis therapy have made it possible to remove middle molecules. Removal of small-middle molecules, such as β2-microglobulin (BMG), can now be achieved with conventional hemodialysis, and removal of large-middle molecules has become a target, particularly for 1-microglobulin (AMG, 33 kD). The AMG reduction rate has emerged as a target for improvement of various clinical symptoms, but the effects on prognosis have yet to be determined. The "Japanese study of the effects of AMG (α1-microglobulin) reduction rates on survival" (JAMREDS) was started in April 2020, with the goal of determining if the AMG reduction rate associates with the risk of mortality and cardiovascular disease (CVD) events...
February 4, 2024: Blood Purification
https://read.qxmd.com/read/38310862/the-changes-in-relative-blood-volume-during-dialysis-are-characterized-by-ultrafiltration-rate-and-predialysis-blood-test-values
#10
JOURNAL ARTICLE
Tomoyuki Tanaka, Yoshifumi Kawakubo, Takeshi Shigematsu, Haruhiko Nishimura
INTRODUCTION: Continuous monitoring of relative blood volume (percentage BV) in hemodialysis (HD) is critical for determining dry weight and preventing intradialytic hypotension. However, the cause of the blood volume variation remains unknown. This research aims to examine factors that influence the percentage BV. METHODS: We devised a formula based on coefficients ("a," "τ" and "b") to predict changes in percentage BV. "a" denotes a significant decrease in percentage BV in the early stages of HD...
February 4, 2024: Blood Purification
https://read.qxmd.com/read/38310853/global-scientific-trends-in-continuous-renal-replacement-therapy-from-2000-to-2023-a-bibliometric-and-visual-analysis
#11
JOURNAL ARTICLE
ZhongBin Tao, YanDong Feng, Jie Wang, YongKang Zhou, JunQiang Yang
INTRODUCTION: Continuous renal replacement therapy (CRRT) is one of the most widely used blood purification and organ support methods in the ICU. However, the development process, the current status, hotspots, and future trends of CRRT remain unclear. METHOD: The WoSCC database was used to analyze CRRT research evolution and theme trends. VOSviewer was used to construct co-authorship, co-occurrence, co-citation, and network visualizations. Citespace is used to detect bursts for co-occurrence items...
February 4, 2024: Blood Purification
https://read.qxmd.com/read/38286112/erratum
#12
(no author information available yet)
No abstract text is available yet for this article.
January 29, 2024: Blood Purification
https://read.qxmd.com/read/38281478/effect-of-mechanical-vibration-on-kinetics-of-solute-adsorption
#13
JOURNAL ARTICLE
Gonzalo Ramírez-Guerrero, Thiago Reis, Anna Lorenzin, Matteo Marcello, Massimo de Cal, Monica Zanella, Claudio Ronco
INTRODUCTION Hemoadsorption with new sorbent cartridges is an emerging extracorporeal blood purification technique. Flow distribution inside the sorbent is one of the main issues concerning the device's performance and optimal sorbent utilization. In this experiment, we aimed to investigate the efficacy of vibration during adsorption by measuring the removal of Vancomycin. METHODS In this experimental study, 1,000 mL of saline with 10 g of Vancomycin was circulated in a closed circuit (set flow of 250 mL/min) simulating a hemoadsorption blood run using HA380 minimodule cartridge containing 75 g of wet resin...
January 27, 2024: Blood Purification
https://read.qxmd.com/read/38262384/in-vitro-removal-of-protein-bound-retention-solutes-by-extracorporeal-blood-purification-procedures
#14
JOURNAL ARTICLE
Claudia Schildböck, Stephan Harm, Jens Hartmann
When the kidneys or liver fail, toxic metabolites accumulate in the patient's blood, causing cardiovascular and neurotoxic complications and increased mortality. Conventional membrane-based extracorporeal blood purification procedures cannot remove these toxins efficiently. The aim of this in-vitro study was to determine whether commercial hemoperfusion adsorbers are suitable for removing protein-bound retention solutes from human plasma and whole blood as well as to compare the removal to conventional hemodialysis...
January 23, 2024: Blood Purification
https://read.qxmd.com/read/38262381/angiopoietin-as-a-novel-prognostic-marker-in-kidney-disease
#15
Abdullah B Yildiz, Sidar Copur, Cem Tanriover, Furkan Yavuz, Sezan Vehbi, Abduzhappar Gaipov, Lorenza Magagnoli, Paola Ciceri, Mario Cozzolino, Mehmet Kanbay
Renal injury is among the leading causes of morbidity and mortality, however, there are no reliable indicators for determining the likelihood of developing CKD, CKD progression or AKI events. Vascular growth factors called angiopoietins have a role in endothelial function, vascular remodeling, tissue stabilization and inflammation, and have been implicated as prognostic and predictive markers in AKI. Although the exact mechanism of the relationship between kidney injury and angiopoietins is unknown, this review demonstrates that AKI patients have higher angiopoietin-2 levels and that higher angiopoietin-1 to angiopoietin-2 ratio may potentially be linked with a reduced risk of the chronic kidney disease progression...
January 23, 2024: Blood Purification
https://read.qxmd.com/read/38228111/protein-kinase-n1-level-predicts-acute-kidney-injury-in-patients-undergoing-cardiac-surgery%C3%AF-a-prospective-cohort-study
#16
JOURNAL ARTICLE
Lianjiu Su, Fangfang Zhu, Jiahao Zhang, Edward Z Cao, Cheng Yang, Haibing Sun, Xiaofang Jiang, Xiaozhan Wang, Jing Wang, Zhiyong Peng
INTRODUCTION: The objective of this study is to examine the utility of protein kinase N1 (PKN1) as a biomarker of cardiac surgery-associated AKI (CSA-AKI). METHODS: A prospective cohort study of 110 adults undergoing on-pump cardiac surgery was conducted. The associations between post-operative PKN1 and CSA-AKI, AKI severity, need for renal replacement therapy (RRT), duration of AKI, length of ICU stay and post-operative hospital stay were evaluated. RESULTS: Patients were categorized into three groups according to PKN1 tertiles...
January 16, 2024: Blood Purification
https://read.qxmd.com/read/38228100/effects-of-extracorporeal-blood-flow-rates-on-patient-tolerance-for-lixelle%C3%A2-treatment-during-outpatient-hemodialysis
#17
JOURNAL ARTICLE
Onkar S Dhande, Arnaud Teichert, Varshasb Broumand, Haruki Kakita, Ayaka Kitamura, Masaaki Fukunishi, Christos P Argyropoulos, Eva Czirr, Peter J Nelson
INTRODUCTION: Accumulation of β2-microglobulin (B2M) in dialysis patients contributes to several comorbidities of end stage kidney disease (ESKD). The LIXELLE® device adsorbs B2M from blood using sorbent bead technology. Studies in Japan showed LIXELLE treatment during hemodialysis (HD) at blood flow rates up to 250 mL/min removes B2M above HD alone and is well-tolerated. We investigated tolerance for LIXELLE treatment during HD at higher HD blood flow rates standard in the United States (US)...
January 16, 2024: Blood Purification
https://read.qxmd.com/read/38228097/application-of-lipid-apheresis-in-acute-lipogenic-pancreatitis
#18
JOURNAL ARTICLE
Yan Yu, Fang Yuan, Pan'ai Song, Cuifang Sun, Hao Xiong, Jie Song
INTRODUCTION: Recently, the incidence of hypertriglyceridemia-associated pancreatitis(HTG-AP) has been increasing. The pathogenesis of lipogenic pancreatitis is not fully understood.This study aimed to retrospectively analyze the laboratory data, clinical manifestations, and prognosis of patients with lipid-derived pancreatitis who received lipid purification,to explore whether lipid purification is a better treatment for acute hyperlipidemic pancreatitis . METHODS: In this study, we enrolled five subjects diagnosed with HTG-AP at the Second Xiangya Hospital of Central South University between 2021 and 2022...
January 16, 2024: Blood Purification
https://read.qxmd.com/read/38219716/seraph-100-microbind-affinity-blood-filter-does-not-clear-antibiotics-an-analysis-of-antibiotic-concentration-data-from-purify-obs
#19
JOURNAL ARTICLE
Jesse P DeLuca, Daniel J Selig, Pooja Vir, Chau V Vuong, Jeffrey Della-Volpe, Ian M Rivera, Caroline Park, Benjamin Levi, Kathleen P Pratt, Ian J Stewart
INTRODUCTION: Novel hemoperfusion systems are emerging for the treatment of sepsis. These devices can directly remove pathogens, pathogen-associated molecular patterns, cytokines, and other inflammatory markers from circulation. However, significant safety concerns such as potential antibiotic clearance need to be addressed prior to these devices being used in large, clinical studies. METHODS: Prospective, observational study of 34 participants undergoing treatment with the Seraph 100® Microbind Affinity Blood Filter (Seraph 100) device at 6 participating sites in the United States...
January 13, 2024: Blood Purification
https://read.qxmd.com/read/38198755/treatment-of-hemodialysis-vascular-access-repeated-stenosis-with-paclitaxel-coated-balloon-angioplasty-a-retrospective-study
#20
JOURNAL ARTICLE
Chen Chao, Gao Jun, Gong Feng, Liu Lihua, Shi Peng, Ma Shengyin
Introduction To report our experience of angioplasty with Paclitaxel-coated balloon (PCB) versus common balloon (CB) for the treatment of repeated failing vascular access. Methods Retrospective, single-center analysis consisting of 88 patients treated with percutaneous transluminal angioplasty (PTA) in the period from October 2020 through December 2021. Patients were divided into two groups according to the type of treatment as Paclitaxel-coated balloon (n=41) and common balloon (n=47). We analyzed target lesion primary patency and vascular access primary patency for 6 months, and the rate of complications...
January 10, 2024: Blood Purification
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