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Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism

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https://read.qxmd.com/read/30721993/pellagra-and-alcohol-dependence-syndrome-findings-from-a-tertiary-care-addiction-treatment-centre-in-india
#1
Venkata Lakshmi Narasimha, Suhas Ganesh, Sarath Reddy, Lekhansh Shukla, Diptadhi Mukherjee, Arun Kandasamy, Prabhat K Chand, Vivek Benegal, Pratima Murthy
Aim: To define the prevalence and clinical presentation of pellagra, a multi-systemic disease caused by the deficiency of niacin, in patients admitted to a tertiary addiction treatment centre in southern India, with alcohol dependence syndrome (ADS)-(ICD10). Methods: Review of the health records of 2947 patients who received inpatient care for ADS between 2015 and 2017. Results: Out of 2947, 31 (1%) were diagnosed with pellagra. Nearly two-thirds (64...
February 5, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30721965/how-to-interpret-hair-etg-concentrations-in-individuals-with-high-body-mass-index-brief-commentary-on-influence-of-body-mass-index-on-hair-ethyl-glucuronide-concentrations
#2
Cleo L Crunelle, Michel Yegles, Hugo Neels
Body mass index (BMI) is a variable that complicates the interpretation of the alcohol metabolite ethyl glucuronide (EtG) in hair. However, direction on how EtG should currently be interpreted within individuals consuming moderate and excessive daily amounts of alcohol related to their BMI is lacking. In light of interpretation of EtG in individuals with high BMI, we present post hoc analysis of earlier data regarding the effect of BMI on hair EtG concentrations.
February 5, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30715164/the-methanol-poisoning-outbreaks-in-iran-2018
#3
Hamidreza Aghababaeian, Ladan Araghi Ahvazi, Abbas Ostadtaghizadeh
Aims: To present epidemiological data, probable causes and lessons learned from the outbreak of methanol poisoning in Iran in September 2018, and relate this to the increasing incidence of methanol poisoning worldwide over recent decades. Method: Analysis of all available reliable field information, official news reports and reports from the country's forensic medicine organization and the Ministry of Health. Results: Overall, 768 people in Iran were documented as poisoned from September 7 to October 7 2018 by consuming an informal alcohol containing methanol, of whom 76 died (10...
January 31, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30649160/does-self-reported-or-behavioral-impulsivity-predict-subjective-response-to-low-dose-alcohol
#4
Benjamin L Berey, Robert F Leeman, Brian Pittman, Nicholas Franco, Suchitra Krishnan-Sarin
Aims: Subjective response to alcohol and impulsivity are both independent predictors of alcohol use and may be related risk factors for alcohol use disorders (AUDs). Recent findings suggest that more impulsive individuals may experience higher risk subjective response patterns at moderate-to-high doses of alcohol. However, whether these relationships are observable early in a drinking occasion remains an open question. This study examined multiple measures of impulsivity in relation to subjective response following low-dose alcohol...
January 11, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30608570/individual-and-social-factors-related-to-trajectories-of-blackouts-among-underage-drinkers-in-the-emergency-department
#5
Erin E Bonar, Jason E Goldstick, Rebecca M Cunningham, Anne C Fernandez, Alan K Davis, Mark A Ilgen, Maureen A Walton
Aims: Alcohol-related blackouts can result in acute injuries and other negative outcomes. Among underage risky drinkers, we examined longitudinal trajectories of blackout frequency following an emergency department (ED) visit, and identified baseline characteristics associated with blackout trajectory membership. Methods: Participants (ages 14-20; N = 836) attending an ED who screened positive for risky drinking and enrolled in a randomized-controlled trial of brief alcohol interventions were assessed at baseline, 3-, 6-, and 12-months...
January 4, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30608520/3d-analysis-of-philtrum-depth-in-children-with-fetal-alcohol-syndrome
#6
Moritz Blanck-Lubarsch, Dieter Dirksen, Reinhold Feldmann, Cristina Sauerland, Christian Kirschneck, Ariane Hohoff
Aims: Diagnosis of fetal alcohol spectrum disorder (FASD) is complex and difficult. The estimated number of unreported FASD is thus assumed to be substantial. In our cross-sectional study, we aimed to identify possible metric differences in philtrum depth in children with fetal alcohol syndrome (FAS) compared to healthy controls based on non-invasive 3D facial scanning in order to provide an objective, metrical tool improving FASD diagnosis. Methods: Twenty-five children with confirmed FAS and 30 healthy school children without FAS, both in the mixed dentition, were prospectively recruited and 3D facial scans were performed after recording body length, weight and head circumference...
January 4, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30576416/executive-functioning-moderates-responses-to-appetitive-cues-a-study-in-severe-alcohol-use-disorder-and-alcoholic-liver-disease
#7
Warren B Logge, Kirsten C Morley, Paul S Haber, Andrew J Baillie
Aim: To examine subjective and psychophysiological responses to appetitive cues during an alcohol cue reactivity task, and its relation to alcoholic liver disease and assess whether executive functioning is associated with appropriate regulation of cue-elicited responses in individuals with severe alcohol use disorder (AUD). Methods: Seventeen treatment-seeking alcoholic liver disease patients and a control group of treatment-seeking severe AUD participants completed neuropsychological executive functioning measures (Stroop task; Trail-making test) and the cue reactivity task, whereby control (water) and alcohol beverage cues were presented, followed by respective recovery periods...
December 20, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30576413/healthcare-utilisation-morbidities-and-alcohol-use-monitoring-prior-to-alcoholic-psychosis-diagnosis
#8
Harmony Otete, M Kate Fleming, Joe West, Elizabeth Orton
Aims: The aim of this study was to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk. Methods: Using linked general practice and hospitalisation data in England (April 1997 to June 2014), we identified 1731 individuals (≥18 years) with a clinical recorded diagnosis of alcoholic psychosis and 17,310 matched controls without the disorder, we examined all prior general practitioner (family doctor) visits, hospitalisations, medically recorded morbidities and alcohol assessment/interventions records...
December 20, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30541059/maximum-time-between-tests-a-digital-biomarker-to-detect-therapy-compliance-and-assess-schedule-quality-in-measurement-based-ehealth-systems-for-alcohol-use-disorder
#9
Andreas Zetterström, Markku D Hämäläinen, Elin Karlberg, Maria Winkvist, Marcus Söderquist, Patrik Öhagen, Karl Andersson, Fred Nyberg
Aim: To evaluate, in a breathalyzer-based eHealth system, whether the time-based digital biomarker 'maximum time between tests' (MTBT) brings valuable information on alcohol consumption patterns as confirmed by correlation with blood phosphatidyl ethanol (PEth), serum carbohydrate deficient transferrin (CDT) and timeline follow-back data. Method: Data on 54 patients in follow-up for treatment of alcohol use disorder were analysed. Results: The model of weekly averages of 24-log transformed MTBT adequately described timeline follow-back data (P  <  0...
December 12, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30508169/a-review-of-baclofen-overdoses-in-australia-calls-to-a-poisons-information-centre-and-a-case-series
#10
Nazila Jamshidi, Kirsten C Morley, Rose Cairns, Andrew Dawson, Paul S Haber
Aim: to describe trends in baclofen reports to Australia's largest Poisons Information Centre (PIC) and present a case series detailing severity of overdoses. Short summary: PBS data demonstrates baclofen use is increasing in Australia, while calls to NSWPIC illustrate an increase in number of exposures associated with toxicity. Baclofen toxicity may require prolonged intensive care admission. To minimize harms associated, especially with off-label baclofen prescribing for AUD, prescribers should pay careful attention to psychiatric comorbidities, and closely monitor treatment and dispensing...
December 1, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30624639/unhelpful-prescribing-in-alcohol-use-disorder-risk-and-averting-risk
#11
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30566592/higher-creatinine-concentrations-in-ethyl-glucuronide-positive-urine-specimens-collected-from-subjects-in-a-controlled-alcohol-abstinence-program-is-serum-creatinine-a-good-marker-of-renal-function-in-drinkers
#12
Aldo Eliano Polettini, Sergej Bleicher, Johannes Kutzler, Richard Mauerer, Wolfgang Schultis
Aims: The aim of this study was to examine urine creatinine concentrations in drivers submitted to controlled alcohol abstinence programs. Methods: Urine samples (n = 32,210) were screened for ethyl glucuronide (EtG) by immunoassay during a 2-year period. Non-negatives underwent EtG and ethyl sulfate (EtS) confirmation by coupled-column Liquid Chromatography-Tandem Mass Spectrometry. Urine samples were tested for dilution by the analysis of creatinine content with <0...
January 1, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30407502/executive-dysfunction-in-patients-with-korsakoff-s-syndrome-a-theory-driven-approach
#13
W G Moerman-van den Brink, L van Aken, E M L Verschuur, S J W Walvoort, J I M Egger, R P C Kessels
Aims: In addition to amnesia, executive deficits are prominent in Korsakoff's syndrome (KS), yet poorly studied. This study investigates the degree of executive dysfunction in patients with KS for the three main executive subcomponents shifting, updating and inhibition using novel, theory-driven paradigms. Short summary: Compared to healthy controls, patients with KS show impairments on the executive subcomponents shifting and updating, but not on inhibition. Methods: Executive functions were measured with six carefully designed tasks in 36 abstinent patients with KS (mean age 62...
January 1, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30260381/the-incidence-of-alcoholism-in-patients-with-advanced-cancer-receiving-active-treatment-in-two-tertiary-care-centers-in-italy
#14
Raffaele Giusti, Marco Mazzotta, Lucilla Verna, Isabella Sperduti, Francesca Romana Di Pietro, Paolo Marchetti, Giampiero Porzio
Introduction: Substance abuse is frequently under-diagnosed among cancer patients. Alcoholism is a problem afflicting about 18% of the general population. This percentage is higher in hospitalized patients. Previous studies conducted on advanced cancer patients admitted in palliative care units have highlighted this problem only for a small percentage of cases. The objective of the study was to evaluate the incidence of alcoholism in patients with advanced cancer admitted to two Italian Oncology Units for active cancer treatment, using a recognized and validated assessment tool...
January 1, 2019: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30462159/inhibition-by-ethanol-of-shear-stress-induced-formation-of-platelet-thrombi-in-whole-blood
#15
Kazumi Ekawa, Mikio Marumo, Ichiro Wakabayashi
Aims: The risk of thromboatherosclerotic disease is lower in moderate drinkers than in non-drinkers. We investigated the effects of ethanol on platelet aggregation under a condition with shear stress. Short summary: Shear stress-induced formation of platelet thrombi is inhibited by ethanol at its attainable concentrations after drinking. This effect is prominent at the early stage of thrombus formation, being in agreement with inhibitory actions of ethanol on the initial steps of platelet activation such as Ca2+ entry and phospholipase A2 activation...
November 20, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30452537/can-suicide-attempt-be-related-to-problem-drinking-cohort-study
#16
Kristina Dambrauskiene, Virginija Adomaitiene, Rimantas Zalinkevicius, Giedre Jariene, Vigintas Vilkas, Ina Rybakova, Loreta Dunderiene
Aims: Alcohol consumption is a well-established risk factor in suicidal behaviour, but there is still discussion about which factor might imply greater suicide risk-acute alcohol intoxication or being a problems drinkers. The aim of this study was to analyse the association between a suicide attempt and the drinking pattern and to evaluate the risk factors for suicide attempt among problem drinkers versus non-problem drinkers. Short summary: We found that problem drinking (CAGE ≥2) is an important issue in suicide attempts...
November 17, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30423027/effects-of-moderate-ethanol-consumption-on-lipid-metabolism-and-inflammation-through-regulation-of-gene-expression-in-rats
#17
Meegan Justice, Autumn Ferrugia, Joshua Beidler, Jerrold C Penprase, Patricia Cintora, Danielle Erwin, Octavio Medrano, Susan M Brasser, Mee Young Hong
Aims: Epidemiological studies and experimental data from rodent models have reported a non-linear relationship between consumption of alcohol and cardiovascular disease (CVD) risk that suggests that light-to-moderate drinking as opposed to excessive consumption may provide some cardiovascular benefits. The present study examined potential mechanisms by which moderate alcohol consumption may provide a protective effect against CVD. Short summary: Wistar rats exposed for 3 months to a 20% ethanol intermittent-access voluntary drinking paradigm displayed a reduction in epididymal fat, blood glucose and non-HDL and total cholesterol...
November 13, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30346466/stress-and-alcohol-priming-of-brain-toll-like-receptor-signaling-in-alcohol-use-disorder
#18
Fulton T Crews, Ryan P Vetreno
No abstract text is available yet for this article.
November 1, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30339185/alcohol-and-alcoholism-then-now-and-the-future-of-the-red-journal
#19
Lorenzo Leggio, Philippe de Witte, Jonathan Chick
No abstract text is available yet for this article.
November 1, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://read.qxmd.com/read/30204846/new-alcohol-biomarkers-new-challenges
#20
Pablo Barrio, Friedrich Martin Wurst, Antoni Gual
No abstract text is available yet for this article.
November 1, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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