Retina

No abstract text is available yet for this article.

PURPOSE: Limited vitrectomy improves vision degrading myodesopsia (VDM), but the incidence of recurrent floaters post-operatively is not known. We studied patients with recurrent central floaters using ultrasonography and contrast sensitivity (CS) testing to characterize this subgroup and identify the clinical profile of patients at risk of recurrent floaters. METHODS: 286 eyes (203 patients, 60.6±12.9 years old) undergoing limited vitrectomy for VDM were studied retrospectively...

PURPOSE: To investigate povidone-iodine's (PI) temporal efficacy and sterility against bacteria associated with post-injection endophthalmitis in an in vitro study. METHODS: A single PI bottle was opened and tested for sterility and antibacterial efficacy. PI from the open bottle was inoculated onto a blood agar plate (BAP) and evaluated for growth 24 hours later to test sterility; this was repeated for five consecutive days. To test for antibacterial efficacy, PI was instilled onto the surface of plates of Staphylococcus, Streptococcus, Enterococcus, Pseudomonas, and Haemophilus species...

PURPOSE: To describe the phenotypic variability and rates of progression of atrophy in patients with PROM1-associated macular dystrophy (PAMD). METHODS: Patients in this retrospective, longitudinal case series from a tertiary center had clinical exam and multi-modal imaging performed. Areas of retinal pigment epithelium and ellipsoid zone loss over time via OCT were calculated by two independent graders. RESULTS: Fifteen patients from five kindreds with an Arg373Cys mutation in PROM1 were studied...

BACKGROUND Although modern minimally invasive vitreoretinal surgery has improved visual outcomes, post-operative proliferative vitreoretinopathy (PVR) and hypotony remain a cause of poor visual results1,2. The migration and proliferation of retinal pigment epithelial cells and the invading immune cells lead to the formation of adherent membranes3. To prevent worsening of PVR and suppress intraocular inflammation, intravitreal triamcinolone, or in some cases, anti-vascular endothelial growth factor (anti-VEGF) have been used4,5...

PURPOSE: To determine baseline patient characteristics that predict need for glaucoma surgery or blindness in eyes with neovascular glaucoma (NVG) despite intravitreal anti-vascular endothelial growth factor (VEGF) therapy. METHODS: Retrospective cohort study of patients with NVG who had not previously received glaucoma surgery and were treated with intravitreal anti-VEGF injections at the time of diagnosis, from 9/8/11 to 5/8/20 at a large, retina subspeciality practice...

PURPOSE: Intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF) is the standard of care for neovascular age-related macular degeneration (nAMD). However, a small subgroup of patients still experience severe visual impairment, which may be related to the number of IVI administered. METHODS: This retrospective observational study analyzed data from patients with sudden severe visual decline (≥15 Early Treatment Diabetic Retinopathy Study [ETDRS] letters loss between two consecutive IVIs) during anti-VEGF treatment for nAMD...

PURPOSE: To evaluate the pathological process of intraretinal glioses by investigating mass tissues resected from untreated eyes with intraretinal glioses. METHODS: Five patients with intraretinal gliosis without previous conservative treatment were included. All patients underwent pars plana vitrectomy. The mass tissues were excised and processed for pathological study. RESULTS: During surgery, we observed that the intraretinal gliosis mainly affected the neuroretina and the retinal pigment epithelium was not affected...

PURPOSE: To investigate Henle's fiber layer (HFL), outer nuclear layer (ONL), and outer plexiform layer (OPL) thicknesses and areas in the eyes of patients with diabetes with no diabetic retinopathy (NDR), in eyes with non-proliferative diabetic retinopathy without diabetic macular edema (NPDR), and in healthy eyes using a modified directional optical coherence tomography (OCT) strategy. METHODS: In this prospective study, the NDR group included 79 participants, the NPDR group comprised 68, and the control group had 58 participants...

PURPOSE: To introduce a new surgical technique with a beveled vitrectomy probe for the removal of peripheral vitreous cortex remnants (VCR) in primary rhegmatogenous retinal detachment (RRD). METHODS: This study was a retrospective case series. From September 2019 to June 2022, 54 patients with complete or partial posterior vitreous detachment that underwent vitrectomy for primary RRD by a single surgeon were enrolled. DESCRIPTION OF TECHNIQUE: After staining the vitreous with triamcinolone acetonide, the presence of VCR was assessed in detail...

PURPOSE: To present and compare the clinical features and multimodal imaging (MMI) findings of the primary form of multiple evanescent white dot syndrome (MEWDS) and MEWDS secondary to multifocal choroiditis/punctate inner choroidopathy (MFC/PIC). METHODS: A prospective case series. 30 eyes of 30 MEWDS patients were included and divided into the primary MEWDS group and MEWDS secondary to MFC/PIC group. Demographic, epidemiological, clinical characteristics, and MEWDS-related MMI findings of the two groups were compared...

PURPOSE: To report the clinical presentation and outcomes in patients with Valsalva retinopathy. METHODS: Retrospective case series of patients diagnosed with Valsalva retinopathy between June 1, 2010 and May 31, 2020. Clinical notes, operative reports, fundus photography, and optical coherence tomography images were reviewed. RESULTS: The study comprised 58 eyes of 58 patients. The most common causes were lifting (34.4%), vomiting (20.6%), straining (20...

PURPOSE: Retinal vasculitis or vascular occlusion (RV/RO) have been reported following brolucizumab for neovascular age-related macular degeneration. This systematic literature review evaluated RV/RO events after brolucizumab in real-world practice. METHODS: Systematic literature searches identified 89 publications; 19 were included. RESULTS: Publications described 63 patients (70 eyes) with an RV/RO event following brolucizumab. Mean age was 77...

PURPOSE: To review the literature on eyes with concurrent rhegmatogenous retinal and choroidal detachment (RRD-CD). METHODS: Several databases were searched for "rhegmatogenous retinal detachment" AND "choroidal detachment" through October 2022. All English language primary literature was reviewed. RESULTS: Studies demonstrated that eyes with RRD-CD were very uncommon, and had diminished baseline visual acuity (VA) and intraocular pressure (IOP) compared to eyes with RRD only...

PURPOSE: To organize, categorize and create a quick reference guide for the use of intravitreal antibiotics alternatives to the standard combination of vancomycin and ceftazidime for the treatment of endophthalmitis. METHODS: A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. We searched for all available information regarding intravitreal antibiotics in the last 21 years...

PURPOSE: We assessed outcomes of eyes with neovascular age-related macular degeneration (nAMD) that switched from proactive (treat-and-extend) to reactive (pro re nata) treatment regimen after developing macular atrophy (MA) or submacular fibrosis (SMFi). METHODS: Data were collected from a retrospective analysis of a prospectively designed, multinational registry of "real-world" nAMD treatment outcomes. Eyes without MA or SMFi when starting treatment with a vascular endothelial growth factor inhibitor regimen that subsequently developed MA or SMFi were included...

PURPOSE: To establish an analysis method using diffeomorphic image registration and evaluate microvascular displacement through epiretinal membrane (ERM) removal. METHODS: Medical records of eyes that underwent vitreous surgery for ERM were reviewed. Postoperative optical coherence tomography angiography (OCTA) images were converted to the corresponding preoperative images according to a configured algorithm using diffeomorphism. RESULTS: Thirty-seven eyes with ERM were examined...

PURPOSE: To evaluate the efficacy of anterior segment optical coherent tomography (AS OCT) in estimating the length of the pars plana and optimizing sclerotomy entry site in vitrectomy for highly myopic eyes, facilitating membrane peeling. METHODS: 23 eyes with myopic traction maculopathy were studied. The pars plana was examined using 2 methods: preoperative AS OCT; and intraoperative measurement. The distance from the limbus to the ora serrata in 2 groups was measured to compare differences in length...

PURPOSE: To calculate the retinal surface alternatively in contact with gas and aqueous due to fluid sloshing during daily activities such as ocular saccade, turning the head, standing up and being a passenger of a braking car. METHODS: Fluid dynamics of aqueous and gas tamponade were reproduced via computational methods using the OpenFOAM® open-source library. The double-fluid dynamics was simulated by the volume of fluid method and setting the contact angle at the aqueous-gas-retina interface...

No abstract text is available yet for this article.