De-Wei An, Yu-Ling Yu, Azusa Hara, Dries S Martens, Wen-Yi Yang, Yi-Bang Cheng, Qi-Fang Huang, Kei Asayama, Katarzyna Stolarz-Skrzypek, Marek Rajzer, Peter Verhamme, Tim S Nawrot, Yan Li, Jan A Staessen
OBJECTIVES: We undertook time-stratified analyses of the National Health and Nutrition Examination Survey in the US to assess time trends (1999-2020) in the associations of blood lead (BL) with blood pressure, mortality, the BL-associated population attributable fraction (PAF). METHODS: Vital status of participants, 20-79 years old at enrolment, was ascertained via the National Death Index. Regressions, mediation analyses and PAF were multivariable adjusted and standardized to 2020 US Census data...
March 15, 2024: Journal of Hypertension
Yiqian Zhang, Qiufen Sun, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Huaidong Du, Ling Yang, Yiping Chen, Xiaoming Yang, Xiaofang Chen, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv
OBJECTIVE: How traditional cardiovascular disease (CVD) risk factors are related to long-term blood pressure change (BPC) or trajectories remain unclear. We aimed to examine the independent associations of these factors with 15-year BPC and trajectories in Chinese adults. METHODS: We included 15 985 participants who had attended three surveys, including 2004-2008 baseline survey, and 2013-2014 and 2020-2021 resurveys, over 15 years in the China Kadoorie Biobank (CKB)...
March 14, 2024: Journal of Hypertension
Fan Yang, Yijie Wang, Ziwei Zhang, Yangjie Zeng, Mengsi Liu, Zhaoyang Tian, Ping Li
OBJECTIVE: Adrenal venous sampling (AVS) is key for primary aldosteronism subtype identification. However, the value of adrenocorticotropic hormone (ACTH) stimulation in AVS is still controversial. METHODS: In this prospective study, we investigated the role of continuous ACTH infusion on the performance and interpretation of bilateral simultaneous AVS using a standard protocol in 59 primary aldosteronism patients. We analyzed the selectivity index and lateralization index in AVS pre and post-ACTH and estimated the prognosis of patients who underwent adrenalectomy with different cutoff points of lateralization index post-ACTH...
March 11, 2024: Journal of Hypertension
Felipe González-Alvarez, Bruno Estañol, Jesús Antonio González-Hermosillo, Francisco Javier Gómez-Pérez, Karla Maria Tamez-Torres, Eduardo Peña, Carlos Cantú, Erwin Chiquete, José Sifuentes-Osornio, Maria Del Carmen Alba-Lorenzo, Dulce Andrea Celestino-Montelongo, Guadalupe E Salazar-Calderón, Jose de Jesus Aceves Buendia
The COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has emerged as a global public health concern and its sequels have barely started to outcrop. A good percentage of patients who suffered from COVID-19 are prone to develop long-COVID or post-COVID condition (PCC), a multisystemic, heterogeneous, chronic disorder. Patients with PCC may experience diverse manifestations, of which cardiovascular and neurological symptoms are among the most frequently reported...
March 11, 2024: Journal of Hypertension
Alejandro de la Sierra, Natalie Staplin, Luis M Ruilope, Manuel Gorostidi, Ernest Vinyoles, Julián Segura, Colin Baigent, Bryan Williams
OBJECTIVE: It has been suggested that a blunted nocturnal blood pressure (BP) decline is associated with a poor prognosis. Nevertheless, it remains unclear if an abnormal dipping is deleterious per se or it merely reflects an elevated BP during sleep. We aimed to assess the prognostic value of nocturnal BP decline, with or without concomitant elevated nocturnal BP. METHODS: Vital status and cause of death were obtained from death certificates in 59 124 patients, enrolled in the Spanish ABPM Registry between 2004 and 2014 (median follow-up: 10 years)...
March 6, 2024: Journal of Hypertension
Germaine Loo, Troy Puar, Roger Foo, Tiong Kiam Ong, Tzung-Dau Wang, Quang Ngoc Nguyen, Chee Tang Chin, Calvin W L Chin
Hypertension remains the leading modifiable risk factor for cardiovascular disease worldwide. Over the past 30 years, the prevalence of hypertension has been increasing in East and Southeast Asia to a greater extent as compared with other Western countries. Asians with hypertension have unique characteristics. This can be attributed to increased impact of obesity on Asians with hypertension, excessive salt intake and increased salt sensitivity, loss of diurnal rhythm in blood pressure and primary aldosteronism...
March 1, 2024: Journal of Hypertension
Janis M Nolde, Emily Atkins, Simone Marschner, Graham S Hillis, John Chalmers, Laurent Billiot, Mark R Nelson, Christopher M Reid, Peter Hay, Michael Burke, Shirley Jansen, Tim Usherwood, Anthony Rodgers, Clara K Chow, Markus P Schlaich
BACKGROUND: A combination of four ultra-low-dose blood pressure (BP) medications lowered office BP more effectively than initial monotherapy in the QUARTET trial. The effects on average ambulatory BP changes at 12 weeks have not yet been reported in detail. METHODS: Adults with hypertension who were untreated or on monotherapy were eligible for participation. Overall, 591 participants were randomized to either the quadpill (irbesartan 37.5 mg, amlodipine 1...
February 29, 2024: Journal of Hypertension
Aleksi Tarkkonen, Ward Fickweiler, Marika Eriksson, Jennifer K Sun, Lena M Thorn, Paula Summanen, Per-Henrik Groop, Jukka Putaala, Juha Martola, Daniel Gordin
OBJECTIVES: A third of asymptomatic individuals with type 1 diabetes (T1D) show signs of cerebrovascular disease in brain MRI. These signs associate with advanced stages of diabetic retinal disease, but not in mild or moderate retinopathy. We aimed to evaluate a wider spectrum of retinal changes by exploring the relationship between quantitative measures of retinal vessel parameters (RVP) and cerebrovascular changes in T1D. METHODS: We included 146 neurologically asymptomatic individuals with T1D [51% women, median age 40 (33...
February 28, 2024: Journal of Hypertension
Iedda A Brasil, José Cristiano P L Silva, Linda S Pescatello, Paulo Farinatti
Blood pressure (BP) reduction occurs after a single bout of exercise, referred to as postexercise hypotension (PEH). The clinical importance of PEH has been advocated owing to its potential contribution to chronic BP lowering, and as a predictor of responders to exercise training as an antihypertensive therapy. However, the mechanisms underlying PEH have not been well defined. This study undertook a scoping review of research on PEH mechanisms, as disclosed in literature reviews. We searched the PubMed, Web of Science, Scopus, Cumulated Index to Nursing and Allied Health Literature (CINAHL), Cochrane Library, and Sport Discus databases until January 2023 to locate 21 reviews - 13 narrative, four systematic with 102 primary trials, and four meta-analyses with 75 primary trials involving 1566 participants...
February 27, 2024: Journal of Hypertension
Eeva Kokko, Manoj Kumar Choudhary, Aapo Mutanen, Milja Honkonen, Antti Tikkakoski, Jenni K Koskela, Mari Hämäläinen, Eeva Moilanen, Marianna Viukari, Niina Matikainen, Pasi I Nevalainen, Ilkka Pörsti
OBJECTIVES: We examined haemodynamics, focusing on volume balance and forward and backward wave amplitudes, before and after 2.8 years of targeted treatment of primary aldosteronism. Patients with essential hypertension and normotensive individuals were examined for comparison (n = 40 in each group). METHODS: Recordings were performed using radial artery pulse wave analysis and whole-body impedance cardiography. Unilateral aldosteronism was treated with adrenalectomy (n = 20), bilateral aldosteronism with spironolactone-based medication (n = 20), and essential hypertension with standard antihypertensive agents...
February 21, 2024: Journal of Hypertension
Maximilian Seidel, Muhammed F Kiziler, Marios Matiakis, Sebastian Bertram, Simon Wang, Felix S Seibert, Nina Babel, Timm H Westhoff
BACKGROUND: Sleep apnea is associated with hypertension. Metaanalyses indicate that treatment of sleep apnea by continuous positive airway pressure (CPAP) reduces blood pressure (BP) by a mean of 3 mmHg. To date, predictors of BP response to CPAP remain incompletely understood. We hypothesized that the magnitude of CPAP-induced BP reduction depends on baseline apnea-hypopnea index (AHI) and the extent of daytime sleepiness. METHODS: We performed a retrospective study on the association of BP response to CPAP with polysomnographic readings, intensity of sleepiness (measured by Epworth Sleepiness Scale, ESS), and epidemiologic parameters in 2461 patients with obstructive sleep apnea...
February 19, 2024: Journal of Hypertension
Xueyan Lang, Cheng Peng, Yanxiu Zhang, Rong Gao, Bing Zhao, Yilan Li, Yao Zhang
BACKGROUND: The correlation between systolic blood pressure (SBP) and mortality in hypertensive patients with different phenotypes of heart failure (HF) has not been adequately studied, and optimal blood pressure control targets remain controversial. To explore the link between SBP and prognosis in all or three ejection fraction (EF) phenotypes of HF patients with hypertension. METHODS: We analyzed 1279 HF patients complicated by hypertension in a retrospective cohort...
February 16, 2024: Journal of Hypertension
Brendan J Carry, Wayne L Miller
The relationship of blood volume (BV) to systemic blood pressure (BP) is not well defined in resistant hypertension (RH). The goal of this study was to examine the extent to which systemic BP stratified by patient sex would impact BV phenotypes. A retrospective analysis of clinical and quantitative BV data was undertaken in a cohort of ambulatory patients with a history of controlled and uncontrolled RH. We analyzed 253 unique BVs with 54% of patients above goal BP of <150 mmHg. BV phenotypes were highly variable but no correlation of systolic BP to absolute BV or percentage deviation from normal volume was identified in either sex...
February 15, 2024: Journal of Hypertension
Rafael Ramírez-Carracedo, Ignacio Hernández, Rafael Moreno-Gómez-Toledano, Javier Díez-Mata, Laura Tesoro, Claudia González-Cucharero, Beatriz Jiménez-Guirado, Nunzio Alcharani, Laura Botana, Marta Saura, Jose L Zamorano, Carlos Zaragoza
BACKGROUND: Endothelial nitric oxide synthase (NOS3) elicits atheroprotection by preventing extracellular matrix (ECM) proteolytic degradation through inhibition of extracellular matrix metalloproteinase inducer (EMMPRIN) and collagenase MMP-13 by still unknown mechanisms. METHODS: C57BL/6 mice lacking ApoE, NOS3, and/or MMP13 were fed with a high-fat diet for 6 weeks. Entire aortas were extracted and frozen to analyze protein and nucleic acid expression...
February 6, 2024: Journal of Hypertension
Shuqi Wang, Samuel Y S Wong, Benjamin H K Yip, Eric K P Lee
BACKGROUND: It remained unclear whether central blood pressures (BP) was more closely associated with cardiovascular disease (CVD) than brachial BP in different age groups. OBJECTIVES: To investigate the age-stratified association of CVD with brachial and central BPs, and to evaluate corresponding improvement in model performance. METHODS: This cohort study included 34 289 adults without baseline CVD from the UK Biobank dataset. Participants were categorized into middle-aged and older aged groups using the cut-off of age 65 years...
February 1, 2024: Journal of Hypertension
Esther M C Vriend, Thomas A Bouwmeester, Oscar H Franco, Henrike Galenkamp, Aeilko H Zwinderman, Bert-Jan H van den Born, Didier Collard
BACKGROUND: Hypertension can be classified into different phenotypes according to systolic and diastolic blood pressure (BP). In younger adults, these phenotypical differences have different prognostic value for men and women. However, little is known about sex differences in the natural course of different BP phenotypes over time. METHODS: We used baseline and follow-up data from the multiethnic, population-based HELIUS study to assess differences in BP phenotypes over time in men and women aged < 45 years stratified according to baseline office BP into normotension (<140/<90 mmHg), isolated systolic hypertension (ISH, ≥140/<90 mmHg), isolated diastolic hypertension (IDH, <140/≥90 mmHg) or systolic diastolic hypertension (SDH, ≥140/≥90 mmHg)...
January 31, 2024: Journal of Hypertension
Felicia C Derendinger, Annina S Vischer, Philipp Krisai, Thenral Socrates, Christina Schumacher, Michael Mayr, Thilo Burkard
OBJECTIVE: There is an increasing number of cuffless blood pressure (BP) measurement (BPM) devices. Despite promising results when comparing single measurements, the ability of these devices to track changes in BP levels over 24 h related to an initial calibration BP (CalibBP) is unknown. Our aim was to analyse this ability in a cuffless device using pulse transit time. METHODS: We prospectively enrolled 166 participants for simultaneously performed cuffless (Somnotouch-NIBP) and cuff-based (Spacelabs 90217A/IEM Mobil-O-graph) 24 h BPM...
January 24, 2024: Journal of Hypertension
Brent M Egan, Jiexiang Li, Susan E Sutherland, Michael K Rakotz
OBJECTIVE: Statins appear to have greater antihypertensive effects in observational studies than in randomized controlled trials. This study assessed whether more frequent treatment of hypertension contributed to better blood pressure (BP, mmHg) control in statin-treated than statin-eligible untreated adults in observational studies. METHODS: National Health and Nutrition Examination Surveys 2009-2020 data were analyzed for adults 21-75 years (N = 3814) with hypertension (BP ≥140/≥90 or treatment)...
January 18, 2024: Journal of Hypertension
Kumi Sagara, Kenichi Goto, Megumi Maeda, Fumiko Murata, Haruhisa Fukuda
Hypertension is the leading cardiovascular risk factor worldwide. However, in Japan, only 30% of patients have their blood pressure controlled under 140/90 mmHg, and nonadherence to antihypertensives is thought to be a reason for the poor control of hypertension. We therefore sought to assess the adherence to hypertension treatment and to evaluate factors influencing patients' adherence in a large, representative sample of the Japanese population. To this end, we analyzed claims data from the LIFE Study database, which includes 112 506 Japanese adults with newly diagnosed hypertension...
January 18, 2024: Journal of Hypertension
Xiao-Fei Ye, Wen-Yuan-Yue Wang, Xin-Yu Wang, Qi-Fang Huang, Chang-Sheng Sheng, Yan Li, Ji-Guang Wang
BACKGROUND: We investigated seasonal variation in ambulatory blood pressure control in hypertensive patients on clinic blood pressure-guided antihypertensive treatment. METHODS: The study participants were hypertensive patients enrolled in an 8-week therapeutic study. Antihypertensive treatment was initiated with long-acting dihydropyridine calcium channel blockers amlodipine 5 mg/day or the gastrointestinal therapeutic system (GITS) formulation of nifedipine 30 mg/day, with the possible up-titration to amlodipine 10 mg/day or nifedipine-GITS 60 mg/day at 4 weeks of follow-up...
January 18, 2024: Journal of Hypertension
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.