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Jeongyoon Kwon, Yun Mi Yu, Seungyeon Kim, Kyeong Hye Jeong, Euni Lee
BACKGROUND: The prevalence of drug-induced parkinsonism (DIP) has been reported with the use of trimetazidine (TMZ), an antianginal medication available in Asian and European countries. Very few studies have evaluated the association between DIP and TMZ use, and studies using population-based data from national databases are lacking. OBJECTIVES: To investigate the association between DIP and use of TMZ in patients with angina using data from a national healthcare claims database and to determine the predictive factors of DIP in TMZ use...
March 4, 2019: Neuroepidemiology
Xin Wee Chen, Mohd Nazri Shafei, Jafri Malin Abdullah, Kamarul Imran Musa
BACKGROUND: A comprehensive evaluation of interrater reliability is crucial when it comes to multiple coders assessing the stroke outcomes using telephone interview. The reliability between telephone raters is important, as it could affect the accuracy of the findings published. OBJECTIVE: This study aimed to establish the interrater reliability between multiple telephone interviewers when assessing long-term stroke outcomes. METHODS: Patients alive at discharge selected in a retrospective cohort stroke project were recruited in this study...
February 21, 2019: Neuroepidemiology
Tae-Joon Kim, Jee Eun Yoon, Jung A Park, Seung Ku Lee, Min Kyung Chu, Kwang Ik Yang, Won-Joo Kim, Seong-Ho Park, Robert J Thomas, Chol Shin, Chang-Ho Yun
BACKGROUND: Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in -Korean adults is mostly 4.5-12.1%, which is higher than that reported in other Asian populations. This study aimed to diagnose RLS and exclude mimicking conditions in 2 independent samples of Korean adults, and to compare its prevalence to that from previous studies performed in Asian countries. METHODS: Study populations included a (1) nationwide stratified random sample (n = 2,824; age 19-79 years) and (2) community-based cohort (n = 2,685; age 47-79 years)...
February 14, 2019: Neuroepidemiology
Jonviea D Chamberlain, Anne Buzzell, Hans Peter Gmünder, Kerstin Hug, Xavier Jordan, André Moser, Martin Schubert, Marcel Zwahlen, Martin W G Brinkhof
BACKGROUND: Traumatic spinal cord injuries (TSCI) are a neurological condition associated with reduced well-being, increased morbidity and reductions in life expectancy. Estimates of all-cause and cause-specific mortality can aid in identifying targets for prevention and management of contributors for premature mortality. OBJECTIVES: To compare all-cause and cause-specific rates of mortality to that of the Swiss general population; to identify differentials in risk of cause-specific mortality according to lesion characteristics...
February 14, 2019: Neuroepidemiology
Jiahao Chen, Caixia Zhang, Yanjun Wu, Dongfeng Zhang
BACKGROUND: The results of analytical studies show that the association between hypertension and the risk of Parkinson's disease (PD) remains controversial. METHOD: We searched studies related to the association between hypertension and the risk of PD. We pooled the ORs and risk ratios (RRs) with 95% confidence interval (CI) with random effects model and conducted meta-regression to explore potential sources of heterogeneity. Publication bias was estimated by Egger's test and the funnel plot...
February 6, 2019: Neuroepidemiology
Dean Shibata, Astrid Suchy-Dicey, Cara L Carty, Tara Madhyastha, Tauqeer Ali, Lyle Best, Thomas J Grabowski, W T Longstreth, Dedra Buchwald
BACKGROUND: Clinical stroke is prevalent in American Indians, but the risk factors for cerebrovascular pathology have not been well-studied in this population. The purpose of this study was to correlate abnormalities on brain magnetic resonance imaging (MRI) with clinical risk factors in a cohort of elderly American Indians. METHODS: Brain MRI scans from 789 participants of the Strong Heart Study were analyzed for infarcts, hemorrhage, white matter disease, and measures of cerebral atrophy including ventricular and sulcal grade and total brain volume...
January 24, 2019: Neuroepidemiology
Md Mohaimenul Islam, Tahmina Nasrin Poly, Hsuan-Chia Yang, Chieh-Chen Wu, Yu-Chuan Jack Li
BACKGROUND: Psoriasis, a common chronic inflammatory disease, increases the risk of developing multiple sclerosis (MS), but evidence for this outcome is still unclear. However, we performed a meta-analysis of relevant studies to quantify the magnitude of the association between psoriasis and MS. It will help to assess the current state of knowledge, fill the gaps in our existing concern, and make a recommendation for future research. METHODS: PubMed, EMBASE, and the bibliographies of articles were searched for studies published between January 1, 1990, and November 1, 2017, which reported on the association between psoriasis and MS...
January 22, 2019: Neuroepidemiology
Merel C Broers, Carina Bunschoten, Daan Nieboer, Hester F Lingsma, Bart C Jacobs
BACKGROUND: Prevalence and incidence rates of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are required to determine the impact of CIDP on society. We aimed to estimate the prevalence and incidence of CIDP worldwide and to determine the effect of diagnostic criteria on prevalence and incidence. METHOD: A systematic review was conducted for all published incidence and prevalence studies on CIDP until May 18, 2017. Methodological quality was assessed using the Methodological Evaluation of Observational Research checklist...
January 22, 2019: Neuroepidemiology
Xin Cui, Zeyan Liew, Johnni Hansen, Pei-Chen Lee, Onyebuchi A Arah, Beate Ritz
Cancer patients are at lower risk of developing Parkinson's disease (PD) compared with the general population. One explanation is the negative association between smoking and PD, but PD risk is also lower for cancers not related to smoking. Another explanation is survival bias where death from cancer may act as a competing risk. We conducted a large population-based case-control study in Denmark and investigated whether cancer diagnosis reduced the risk of developing PD even after adjusting for important risk factors including smoking, physical activity, and lifetime oestrogen status...
January 18, 2019: Neuroepidemiology
Alice Theadom, Miriam Rodrigues, Gemma Poke, Gina O'Grady, Donald Love, Graeme Hammond-Tooke, Priya Parmar, Ronelle Baker, Valery Feigin, Kelly Jones, Braden Te Ao, Anna Ranta, Richard Roxburgh
BACKGROUND: Previous epidemiological studies of genetic muscle disorders have relied on medical records to identify cases and may be at risk of selection biases or have focused on selective population groups. OBJECTIVES: This study aimed to determine age-standardised prevalence of genetic muscle disorders through a nationwide, epidemiological study across the lifespan using the capture-recapture method. METHODS: Adults and children with a confirmed clinical or molecular diagnosis of a genetic muscle disorder, resident in New Zealand on April 1, 2015 were identified using multiple overlapping sources...
January 18, 2019: Neuroepidemiology
Anna Andreolli, Emanuela Claudia Turco, Giuseppe Pedrazzi, Ettore Beghi, Francesco Pisani
BACKGROUND: The incidence of childhood and adolescence epilepsy varies in different areas and over time. Published reports in the Italian pediatric population are few and there is no information on the incidence of epilepsy using the new clinical definition of the disease signed by the International League Against Epilepsy. An increased risk of epilepsy is reported in subjects who presented with neonatal seizures (NS), but few population-based studies are available that compare incidence and age at onset of epilepsy in children with and without NS...
January 18, 2019: Neuroepidemiology
Ann-Marie Surmava, Laura C Maclagan, Ferhana Khan, Moira K Kapral, Ruth E Hall, Gabrielle deVeber
BACKGROUND: Reported incidence rates of pediatric stroke and transient ischemic attack (TIA) range widely. Treatment gaps are poorly characterized. We sought to evaluate in -Ontario, the incidence and characteristics of pediatric stroke and TIA including care gaps and the predictive value of International Classification of Diseases (ICD) codes. METHODS: A retrospective chart review was conducted at 147 Ontario pediatric and adult acute care hospitals. Pediatric stroke and TIA cases (age < 18 years) were identified using ICD-10 code searches in the 2010/11 Canadian Institute for Health Information's Discharge Abstract Database (CIHI-DAD) and National Ambulatory Care Reporting System (NACRS) databases in the Ontario Stroke Audit...
January 17, 2019: Neuroepidemiology
Tissa Wijeratne, Huiliang Melissa Tang, David Crewther, Sheila Crewther
Migraine is one of the most prevalent neurological disorders among all age groups including the elderly, but the incidence and prevalence of migraine tend to decrease with age. The clinical phenotype of migraine also appears to be different in the elderly patient group in comparison to the younger patient group, with elderly migraine appearing to be more often bilateral and associated with what has become known as "late-life migraine accompaniments. Furthermore, difficulty in the differentiation of migraine from vascular insults such as transient ischemic attacks and amyloid angiopathy and other multiple comorbidities, polypharmacy and age-related changes in pharmacodynamics and pharmacokinetics makes treatments for this cohort challenging but necessary, especially given the worldwide increase in life expectancy, and likelihood of migraine continuing to be a major personal and public health problem...
January 9, 2019: Neuroepidemiology
Elan D Louis
BACKGROUND: With an aging population, it behooves physicians and scientists to gain an understanding of the intersections between aging and human disease. Here, the author reviews the intersections between age, aging, and essential tremor (ET), particularly as these relate to disease epidemiology. SUMMARY: The prevalence and incidence of ET both increase with age, and the former, in an exponential fashion with advanced aging. There is evidence that age may independently drive several features of the natural history of ET (e...
January 9, 2019: Neuroepidemiology
Allison R Kaup, Alexandrea L Harmell, Kristine Yaffe
BACKGROUND: While some personality traits may reduce risk of dementia, this is controversial and has not been studied as much among diverse populations. We examined associations between 2 traits - Conscientiousness and Openness to Experience - and risk of dementia among black and white older adults. METHODS: We studied 875 older adults (ages 71-82, 47% black) without prevalent dementia from the Health, Aging and Body Composition study, who completed the NEO Five-Factor Inventory for Conscientiousness and Openness to Experience...
January 2, 2019: Neuroepidemiology
Yannick Béjot, Henri Bailly, Mathilde Graber, Lucie Garnier, Annabel Laville, Lucile Dubourget, Nathalie Mielle, Corinne Chevalier, Jérôme Durier, Maurice Giroud
BACKGROUND: We aimed to evaluate the impact of the ageing population on temporal trends in burden of stroke and to provide projections for the coming years. METHODS: Stroke cases (ischemic strokes, spontaneous intracerebral hemorrhages, or undetermined strokes) were prospectively identified between 1987 and 2015 in Dijon, France, using a population-based registry. Age-standardized incidence rates of first-ever and recurrent stroke were calculated, and their temporal trends were assessed using age- and sex-adjusted annual incidence rate ratios (RR)...
January 2, 2019: Neuroepidemiology
Yannick Béjot, Kristine Yaffe
No abstract text is available yet for this article.
January 2, 2019: Neuroepidemiology
Giancarlo Logroscino, Marco Piccininni
Amyotrophic lateral sclerosis (ALS) epidemiology has rapidly developed in the last 30 years alongside the evolving changes in concepts in the field of clinical ALS and also due to the recent proposals of new classification system for motor neuron diseases. Many of these changes in the clinical scenario have been determined through the results of ALS population-based studies conducted in the last 20 years primarily in Europe. All the evidences converge to show that ALS risk is different across continents and ethnicities...
2019: Neuroepidemiology
Arttu Kurtelius, Mitja I Kurki, Mikael von Und Zu Fraunberg, Nelli Väntti, Satu Kotikoski, Heidi Nurmonen, Timo Koivisto, Juha E Jääskeläinen, Antti E Lindgren
BACKGROUND AND PURPOSE: To study the penetrance of saccular intracranial aneurysm (IA) disease in children when both parents carry the disease. PATIENTS AND METHODS: The Kuopio IA Patient and Family Database includes all 4,411 IA patients admitted to the Kuopio University Hospital from its defined Eastern Finnish catchment population since 1980. We fused IA database with hospital diagnoses for IA patients and their 46,021 relatives from a national registry to identify couples concordant for IA disease...
November 26, 2018: Neuroepidemiology
Ibrahim Abdollahpour, Alexis A Lizarraga, Saharnaz Nedjat, Mohammad Ali Mansournia, Bianca Weinstock-Guttman
BACKGROUND: Consistent evidence regarding the potential role of medical history in multiple sclerosis (MS) etiology is lacking. OBJECTIVE: The association of medical history variables, that is, head injury and 9 autoimmune diseases with MS onset was investigated. METHODS: This was a population-based incident case-control study in Iran with 547 incident cases and 1,057 general population controls (August 7, 2013 - February 17, 2015). Multiple logistic regression models were used for estimating the adjusted ORs...
November 26, 2018: Neuroepidemiology
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