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Giuseppe Giannaccare, Marco Pellegrini, Federico Bernabei, Fabiana Moscardelli, Marina Buzzi, Piera Versura, Emilio C Campos
PURPOSE: To investigate the comparative effect of allogeneic peripheral blood serum (allo-PBS) and cord blood serum (CBS) eye drops on the status of the corneal subbasal nerve plexus in patients with dry eye disease by using an automated analysis system of in vivo confocal microscopy images. METHODS: This prospective, randomized, double-blind study included 30 patients with severe dry eye disease assigned to receive allo-PBS (group 1) or CBS (group 2) eye drops 8 times a day for 30 days...
May 9, 2019: Cornea
Kamal A M Solaiman, Wael M El-Haig, Ashraf Borʼi, Ahmad S Khalil, Ahmed M B Awad, Hani A Al-Bialy, Basem M Ibrahim
No abstract text is available yet for this article.
May 9, 2019: Cornea
Jason Hooton, Kyeong Hwan Kim, Stephen I Lentz, Nicholas Hicks, Kayla Jones, Kristen McCoy, Shahzad I Mian
PURPOSE: The purpose of this study was to determine the safety of long-term storage and shipping of prestripped, prestained, and preloaded Descemet membrane endothelial keratoplasty (pDMEK) grafts. METHODS: A total of 33 cadaveric corneas were prestripped, prestained, and preloaded using modified Jones tube injectors as pDMEK. The corneas were masked to groups that were prepared <9 hours (control), 48 hours, and 72 hours before unloading and analysis. The 48- and 72-hour tissues were shipped by airfreight on each day before arrival to simulate domestic and international shipping...
May 7, 2019: Cornea
Nitee Ratprasatporn, Supeecha Wittayalertpanya, Wondee Khemsri, Tanittha Chatsuwan, Yuda Chongpison, Tasanee Chamsai, Mayura Wattanakijkarn, Sunee Chansangpetch
PURPOSE: To determine in-use stability and sterility of fortified cefazolin, ceftazidime, vancomycin, amphotericin B, and methylprednisolone eye drops in a simulated inpatient setting with and without a mobile refrigerated container (MR). METHODS: Each drug was prepared and divided into 4 groups: 1) simulated patient use with the MR group: stored at 4°C and kept in the MR during drug administration, 2) simulated patient use without the MR (NoMR) group: stored at 4°C and no MR, 3) refrigerated control group: stored at 4°C, and 4) room temperature control group: stored at room temperature...
May 7, 2019: Cornea
Kévin Pierné, Christophe Panthier, Romain Courtin, Adrien Mazharian, Vael Souedan, Damien Gatinel, Alain Saad
No abstract text is available yet for this article.
May 1, 2019: Cornea
Hugo Y Hsu, Tudor Cosmin Tepelus
No abstract text is available yet for this article.
May 1, 2019: Cornea
Arjun Srirampur, Tarannum Mansoori
No abstract text is available yet for this article.
April 30, 2019: Cornea
Preethika Gandhi, Naveen Radhakrishnan, Isha Khaitan, Muthiah Srinivasan, Venkatesh N Prajna
PURPOSE: To report the clinical features and outcomes of toxic keratitis after application of powdered custard apple seeds for hair washing for head lice infestation. METHODS: Retrospective review of all patients with toxic keratitis after application of powdered custard apple seed for head lice infestation during the time period from January 2015 to December 2017. Demographic details, clinical features, and visual outcomes were documented. RESULTS: Thirty-one eyes of 19 patients with toxic keratitis after application of crushed custard apple seeds for head lice infestation were included in the study...
April 30, 2019: Cornea
Prafulla K Maharana, Shah Nawaz, Deepali Singhal, Vishal Jhanji, Tushar Agarwal, Namrata Sharma, Rasik B Vajpayee
PURPOSE: To evaluate the causes and management outcomes of acquired corneal opacity in a preschool age group (0-5 years) at a tertiary care hospital. METHODS: Medical records of all cases (0-5 years) with acquired corneal opacity presenting to the cornea clinic of a tertiary eye care hospital from February 2013 to January 2014 were evaluated for age of onset, age at presentation, sex, laterality, cause of opacity, visual acuity, nutritional status, and socioeconomic class of the parents...
April 29, 2019: Cornea
Avrey Thau, Oseluese Dawodu, Kamiar Mireskandari, Asim Ali, Nasrin Tehrani, Caroline DeBenedictis, Devang Bhoiwala, William Aultman, Waleed A Alnabi, Benjamin E Leiby, Alex V Levin
PURPOSE: We explored elevated central corneal thickness (CCT) in children with cataracts as possibly reflecting preexisting corneal malformation related to specific cataract morphology. METHODS: All children consecutively seen during the study periods who had cataracts and corneal pachymetry as part of their routine care were enrolled at academic centers in large cities of Canada and the United States. Study data collected included age, sex, CCT, and cataract morphology...
April 29, 2019: Cornea
Clara Álvarez de Toledo, Borja Salvador-Culla, José Carlos López, María Fideliz De la Paz, Rafael I Barraquer, Juan Álvarez de Toledo
PURPOSE: To report the diagnosis, histological findings, and treatment of a patient who developed epithelial ingrowth after Descemet membrane endothelial keratoplasty (DMEK). METHODS: We present the case of a type 2 diabetic 60-year-old man who underwent DMEK for Fuchs dystrophy. Two months after surgery, an epithelial ingrowth in the graft-host interface was suspected. After a 3-month follow-up period in which progressive and centrifugal growth of the epithelial cells in the interface was documented, penetrating keratoplasty (PK) was performed to remove all areas of epithelial ingrowth...
April 27, 2019: Cornea
Alexandra M Papp, Grant A Justin, Christian T Vernau, James K Aden, Brian M Fitzgerald, Gregory P Kraus, Gary L Legault
PURPOSE: To perform a systematic review of the international literature evaluating the risk factors, preventative steps, and treatments for perioperative corneal injuries for nonocular surgery. METHODS: PubMed, Embase, and Evidence-Based Medicine Reviews databases were searched on April 13, 2018. Two hundred four articles were identified with 16 meeting the inclusion criteria. All studies were evaluated for quality and level of evidence. Two types of studies were included...
April 25, 2019: Cornea
Marianne O Price, Kavitha Subramaniam, Matthew T Feng, Francis W Price
No abstract text is available yet for this article.
April 25, 2019: Cornea
Nicolas Cesário Pereira, José Álvaro Pereira Gomes, Aline Silveira Moriyama, Luis Fernando Chaves, Adriana Dos Santos Forseto
PURPOSE: To describe the outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed by cornea fellows during their initial learning curve. METHODS: This prospective study included the first consecutive series of 53 DMEK surgeries performed by 14 corneal fellows at Sorocaba's Ophthalmological Hospital. Best spectacle-corrected visual acuity, endothelial cell density (ECD), and complications were evaluated. RESULTS: Of the eyes without ocular comorbidities and with complete visual acuity measurements, 97% of 33 eyes achieved a best spectacle-corrected visual acuity of ≥20/40 in 6 months...
April 25, 2019: Cornea
Arjun Srirampur, Tarannum Mansoori
No abstract text is available yet for this article.
April 25, 2019: Cornea
Wen Long, Yiming Zhao, Yin Hu, Zhouyue Li, Xiaoxiao Zhang, Wenchen Zhao, Xiao Yang, Dongmei Cui, Klaus Trier
PURPOSE: To investigate the characteristics of corneal biomechanics in Chinese preschool children with different refractive status. METHODS: Study participants were 108 Chinese children (216 eyes) aged 4 to 6 years with a spherical equivalent refraction between -9.00 and +9.00 diopters (D). Cycloplegic refraction was measured using an autorefractor, axial length using an IOL Master (Zeiss, Oberkochen, Germany), and corneal biomechanical metrics and corneal power using an ultra-high-speed camera (Corvis ST; Oculus, Wetzlar, Germany) and Pentacam (Oculus; Menlo Park, CA)...
April 25, 2019: Cornea
Fangkun Zhao, Fengkun Du, Jinsong Zhang, Jun Xu
PURPOSE: To map the publication trends in and explore hotspots of keratoconus research. METHODS: A bibliometric analysis based on the Web of Science Core Collection was conducted to investigate the publication trends in research related to keratoconus. The records extracted were analyzed, and a knowledge map was constructed using VOSviewer v.1.6.10 to visualize the annual publication number, distribution of countries, international collaborations, author productivity, source journals, intellectual base, and research hotspots in the field of keratoconus...
April 25, 2019: Cornea
Muhammet Derda Ozer, Muhammed Batur, Selma Mesen, Serek Tekin, Erbil Seven
PURPOSE: To report long-term results of accelerated corneal collagen cross-linking treatment in patients with progressive keratoconus in the pubertal period. METHODS: Patients with progressive keratoconus aged 14 and younger were retrospectively reviewed. Thirty-five eyes of 23 patients, who were followed for at least 4 years postoperatively, were included in the study. Demographic characteristics, uncorrected visual acuity, best-corrected visual acuity, and corneal topography data were recorded...
April 25, 2019: Cornea
Luca Buzzonetti, Gianni Petrocelli, Paola Valente, Giancarlo Iarossi, Roberta Ardia, Sergio Petroni, Rosa Parrilla
PURPOSE: To compare 3-year iontophoretic transepithelial corneal cross-linking (I-ON CXL) outcomes with epithelium-off collagen cross-linking (epi-off CXL) in pediatric patients. METHODS: Forty eyes of 28 consecutive pediatric patients [mean age 14.3 ± 2.5 (SD) years; range, 9-18 years] with keratoconus were evaluated. Twenty eyes of 15 patients underwent I-ON and 20 eyes of 13 patients epi-off CXL. Mean corrected distance visual acuity, spherical equivalent, maximum keratometry (Kmax), posterior elevation of the thinnest point, and thickness of the thinnest point were evaluated...
April 22, 2019: Cornea
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