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Journal of the American College of Nutrition

Isabel Cardoso, Joanna Michalowska, Sofus C Larsen, Bo Abrahamsen, Berit L Heitmann, Mina N Händel
No abstract text is available yet for this article.
April 16, 2019: Journal of the American College of Nutrition
Rafaella de Andrade Silva Cavalcanti, Alcides da S Diniz, Ilma K G de Arruda
OBJECTIVE: The aim was to verify the relations among intra-erythrocyte folate, serum vitamin B12, and hemoglobin concentrations in women of childbearing age and their association with several socioeconomic and demographic variables, nutritional status, and food consumption in the city of Recife, Northeastern Brazil. METHODS: This was a cross-sectional study with a random sample of 1,210 women of childbearing age from the city of Recife. Concentrations of serum vitamin B12 and intra-erythrocyte folate were analyzed by immunoassay and hemoglobin concentrations by automated determination...
April 16, 2019: Journal of the American College of Nutrition
Qiurong Wang, Rui Guo, Sreejayan Nair, Derek Smith, Bledar Bisha, Anand S Nair, Rama Nair, Bernard W Downs, Steve Kushner, Manashi Bagchi
BACKGROUND: Enzymes are crucial for all aspects of metabolic function. Digestive enzymes from natural sources have been credited with beneficial effects in the digestion and absorption of food. N-SORB is a novel KD120 multienzyme complex (MEC) of metabolically activated enzymes composed of proteases, amylases, lipases, alpha-galactosidase, and glucoamylase from natural sources. These enzymes are encapsulated in a SK713 SLP (non-GMO soy lecithin phospholipid) absorption technology (Prodosome® )...
April 11, 2019: Journal of the American College of Nutrition
Augusta E Modestino, Elaine A Skowronski, Chris Pruitt, Pam R Taub, Karen Herbst, Geert W Schmid-Schönbein, Michael J Heller, Paul J Mills
OBJECTIVE: To examine resting and postprandial peripheral protease activity in healthy controls and individuals with type 2 diabetes mellitus (T2DM) and pre-T2DM. METHODS: Individuals with T2DM or pre-T2DM and healthy controls (mean age 55.8 years) were studied before and for a span of 300 minutes following a single high-calorie McDonald's breakfast. Metalloproteases-2/-9 (MMP-2/-9), elastase, and trypsin activities were assessed in whole blood before and following the meal using a novel high-precision electrophoretic platform...
April 9, 2019: Journal of the American College of Nutrition
Reema Tayyem, Sabika Allehdan, Lana Mustafa, Fida Thekraallah, Fida Al-Asali
OBJECTIVES: Assessing the relationship between maternal diet and pregnancy outcomes is a crucial issue that requires valid dietary assessment tools in this critical period. This study aimed to develop and assess the validity and reproducibility of a culture-specific quantitative food frequency questionnaire (QFFQ) to evaluate the dietary intake of macro- and micronutrients from food in a sample of Jordanian pregnant women. METHODS: A QFFQ was validated against three repeated 24-hour dietary recalls (24-hr recalls)...
April 5, 2019: Journal of the American College of Nutrition
Ranjeet Kumar Nirala, Pratuyasha Dutta, Md Zubbair Malik, Lalita Dwivedi, Tulsidas G Shrivastav, Sonu Chand Thakur
OBJECTIVE: The medicinal plant Betula alba has been used for prevention and treatment of kidney stones. Betulin is one of the main phytochemicals of Betula alba. The aim of this study is to investigate the antioxidant and antiurolithiatic activity of betulin in vitro and in silico. For antioxidant activity, 2, 2-diphenyl-1-picrylhydrazyl (DPPH), total reducing capacity, nitric oxide (NO) radical scavenging assay, and superoxide radical scavenging assay were studied. METHOD: In order to study antiurolithiatic activity, three assays such as crystallization, nucleation, and aggregation of oxalate crystal in urine were performed...
April 1, 2019: Journal of the American College of Nutrition
Sunghee Lee, Eun Young Kim, Chol Shin
OBJECTIVE: Although brain atrophy is a natural process of healthy aging, diet may play a role in delaying the process across age. We sought to investigate how food groups associate brain region-specific volume changes over 4 years in a general population. METHODS: We obtained data from the Korean Genome and Epidemiology Study on 848 community-dwelling individuals. The participants completed a dietary examination using a food frequency questionnaire between 2005 and 2006 to determine habitual usual intakes of food consumption and two brain magnetic resonance imaging (MRI) scans between 2011 and 2014 and between 2015 and 2017, respectively...
March 21, 2019: Journal of the American College of Nutrition
Lílian L Lopes, Josefina Bressan, Maria do Carmo G Peluzio, Helen Hermana M Hermsdorff
Epigenetic mechanisms may play an important role in the etiology of obesity and cardiometabolic diseases, by activating or silencing the related-genes. Scientific evidence has suggested that LINE-1 methylation is associated with body composition and obesity-related diseases, including insulin resistance, type 2 diabetes mellitus, and cardiovascular disease (CVD). It also has been evaluated as predictor of weight loss. The studies' results are still conflicting, and positive and negative associations have been found to LINE-1 methylation regarding adiposity and cardiometabolic markers...
March 12, 2019: Journal of the American College of Nutrition
Mehdi Sadeghian, Omid Sadeghi, Ahmad Esmaillzadeh
We have with great interest read the recent article by Hajihashemi et al. which systematically reviewed and meta-analyzed a number of published clinical trials about the effect of whole grains on serum levels of hs-CRP (high sensitiviy C-reactive protein), IL-6 (interlukin-6), TNF-α (tumor necrosis factor-α). The findings suggested that consumption of whole grains significantly decreased serum levels of hs-CRP and IL-6, but not TNF-α, compared with the control group. It is an interesting study, but there are some methodological limitations and missing data that need to be addressed...
March 11, 2019: Journal of the American College of Nutrition
Rijané Swart, Aletta E Schutte, Johannes M van Rooyen, Wayne Smith, Catharina M C Mels
OBJECTIVE: Selenium plays an important physiological role as component for antioxidant selenoproteins such as glutathione peroxidase (GPx). Since oxidative stress contributes to hypertension development, it is likely that selenium deficiency may contribute to the burden of cardiovascular disease. To better understand the involvement of selenium and GPx in the early development of cardiovascular disease, we investigated in young, healthy black and white African men and women whether measures of the micro- and macrovasculature are related to selenium and GPx activity...
March 1, 2019: Journal of the American College of Nutrition
Suvajyoti Guha, Nesrine Bouhrira, Mark J Antonino, Joshua S Silverstein, Jeffrey Cooper, Matthew R Myers
OBJECTIVE: Blenderized diets are gaining increasing popularity among enteral tube users. Connectors in gastrostomy tubes (G-tubes) are undergoing standardization to reduce misconnections. These standardized G-tubes are referred to as ENFit G-tubes. This study was performed to quantify the in vitro performance of existing (legacy) G-tubes and compare them with ENFit G-tubes for blenderized diets. METHOD: Patient blenderized diet recipes and practices were obtained through patient advocacy groups...
March 1, 2019: Journal of the American College of Nutrition
Harry G Preuss, Nate Mrvichin, Gilbert R Kaats, Debasis Bagchi, Dallas Clouatre
BACKGROUND: Medical professionals attribute a crucial role in the development of several age-related, chronic health maladies to glucose-insulin perturbations - particularly, discernible insulin resistance (IR). However, little information is available concerning the degree to which relatively minor changes in IR participate over time in overall aging population, e.g., when circulating glucose and/or insulin concentrations are consistently within the higher end of normally accepted ranges...
February 27, 2019: Journal of the American College of Nutrition
Chin-Lin Hsu, Yu-Hsin Hou, Ci-Sian Wang, Shih-Wei Lin, Bo-Yi Jhou, Chin-Chu Chen, Yen-Lien Chen
OBJECTIVE: Obesity has become one of the world's biggest issues. This condition has a great impact on several metabolic and chronic diseases. For example, obesity is often accompanied by hyperuricemia or gout. However, few drugs are available for the treatment of obesity. The present study is to evaluate the antiobesity effect of Lactobacillus plantarum GKM3 in high-fat-diet-induced obese rats and whether taking L plantarum GKM3 can effectively reduce uric acid accumulation caused by obesity and ameliorate other harmful factors...
February 22, 2019: Journal of the American College of Nutrition
Ilaria Russo, Chiara Del Giorno, Ivana Giangrieco, Najla Hajji, Maria Antonietta Ciardiello, Paola Iovino, Carolina Ciacci
OBJECTIVE: Celiac disease is an immune-mediated disease of the intestine triggered by gluten. Gluten elicits, in genetically susceptible individuals, cytokine responses that are then transmitted to the immunocompetent cells. Vegetables and fruit have anti-inflammatory and antioxidant properties with a protective effect on intestinal epithelium. Kiwifruit is known to have beneficial effects on the intestinal tissues, and it is the only plant food containing the peptide kissper, with anti-inflammatory properties...
February 22, 2019: Journal of the American College of Nutrition
Wendi Liu, Peng Zhang, Xin Zhao, Maocheng Sang, Xiaotong Liu, Lu Liu, Shiyan Liu, Haiyue Lin, Zhongna Sang
OBJECTIVE: The aim of this research was to determine the correction coefficients of different spot urinary iodine concentrations (UICs) in a day to predict the early morning UIC, to make the different spot UICs of a day comparable in assessing iodine status in the same population. METHODS: In total, 424 participants aged 18 to 28 years were recruited from Tianjin, China. Three spot urine samples were collected from each participant during three periods of the day (6:30-7:00, 10:00-10:30, and 16:00-16:30)...
February 15, 2019: Journal of the American College of Nutrition
Michelle E Baker, Kristen N DeCesare, Abby Johnson, Kathleen S Kress, Cynthia L Inman, Edward P Weiss
OBJECTIVE: Healthful dietary patterns have constituents that are known to improve exercise performance, such as antioxidants, nitrates, and alkalizing effects. However, ergogenic effects of such diets have not been evaluated. We hypothesized that a short-term Mediterranean diet results in better exercise performance, as compared to a typical Western diet. METHODS: Eleven recreationally active women (n = 7) and men (n = 4) (body mass index, 24.6 ± 3...
February 13, 2019: Journal of the American College of Nutrition
Gail Cresci, Michelle Beidelschies, Julie Tebo, Alan Hull
The need to educate and train future physicians about nutrition and wellness has become increasingly apparent in the past decade. A rising incidence of chronic health conditions with a nutrition background (e.g., obesity, cardiovascular disease, type 2 diabetes) has led to an even greater need for nutrition educational content in medical school curricula so that physicians may counsel patients regarding their lifestyle factors. This review provides an overview of the successful development and integration of a nutrition thread in a 5-year medical school curriculum...
February 6, 2019: Journal of the American College of Nutrition
Shahrokh Bagheri, Mostafa Moradi Sarabi, Peyman Khosravi, Reza Mohammadrezaei Khorramabadi, Saeid Veiskarami, Hassan Ahmadvand, Mahtab Keshvari
INTRODUCTION: Diabetes mellitus (DM) affects many patients all over the world. It involves different parts of the body, such as brain, eyes, kidneys, vessels, and so on. The lack of balance between free radicals and antioxidants is a possible mechanism involved in the pathogenesis of diabetes. Antioxidant treatment, especially natural forms, can be a beneficial solution. Therefore, we evaluated the effects of Pistacia atlantica oleoresin (PAO) on oxidative stress markers and antioxidant enzymes expression in diabetic rats...
February 4, 2019: Journal of the American College of Nutrition
Yi Zhang, Dian-Zhong Zhang
OBJECTIVE: Our aim was to examine the relationship between nut consumption and metabolic syndrome (MetS). METHODS: The electronic databases of PubMed, Web of Science, and Embase were searched up to November 2018 for observational studies on the relationship between nut consumption and MetS. The pooled relative risk (RR) of MetS for the highest versus lowest category of nut consumption, as well as their corresponding 95% confidence intervals (CIs) were calculated...
February 4, 2019: Journal of the American College of Nutrition
Sayantan Maitra, Arnab De, Bhaskar Das, Sudipendra Nath Roy, Ranadhir Chakraborty, Amalesh Samanta, Subhrajit Bhattacharya
OBJECTIVE: Tea (Camellia sinensis Linn.; family: Theaceae) is popular as a stimulant beverage across the globe and is also utilized as a functional antioxidant in alternative medicine. This study has evaluated the impact of seasonal variation on phyto-constituents of tea. METHOD: The antiproliferative potential of methanolic extracts of tea leaves collected in the rainy season (MECR) was compared with the extract of tea leaves collected in the autumn season (MECA) of the same mother plant...
January 29, 2019: Journal of the American College of Nutrition
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