Shouqiang Li, Cheng Chen, John Lof, Elizabeth A Stolze, Jiri Sklenar, Xucai Chen, John J Pacella, Flordeliza S Villanueva, Terry O Matsunaga, E Carr Everbach, Stanley J Radio, Sherry N Westphal, Sruti Shiva, Feng Xie, Xiaoping Leng, Thomas R Porter
BACKGROUND: Acoustically activatable perfluoropropane droplets (PD) can be formulated from commercially available microbubble preparations. Diagnostic transthoracic ultrasound frequencies have resulted in acoustic activation (AA) predominately within myocardial infarct zones (IZ). OBJECTIVE: We hypothesized that the AA area following acute coronary ischemia/reperfusion (I/R) would selectively enhance the developing scar zone, and target bioeffects specifically to this region...
March 5, 2024: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine