journal
https://read.qxmd.com/read/38602613/male-patients-with-primary-sj%C3%A3-gren-s-syndrome-have-unique-clinical-manifestations-and-circulating-lymphocyte-profiles
#1
JOURNAL ARTICLE
Huan Liu, Jiangshui Yuan, Xueying Tan, Weiqing Song, Shuguo Wang
OBJECTIVES: We aimed to explore the relationship between clinical characteristics and circulating lymphocyte profiles in Chinese male patients with primary Sjögren's syndrome (pSS). METHOD: Data from 397 patients with pSS were analyzed retrospectively. 37 were male, which is a prevalence of 9.3%. The clinical, laboratory, and immunophenotypic profiles of peripheral blood lymphocyte subsets were compared between male and female pSS patients. RESULTS: Male patients with primary Sjögren's syndrome have unique clinical manifestations and circulating lymphocyte profiles...
April 11, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38602612/characteristics-of-the-oral-microbiota-in-patients-with-primary-sj%C3%A3-gren-s-syndrome
#2
JOURNAL ARTICLE
Yiwen Xie, Yu Fan, Miaotong Su, Yukai Wang, Guohong Zhang
OBJECTIVE: Primary Sjögren's syndrome (pSS) is an autoimmune disease with unknown etiology that is considered to be related to environmental and genetic factors. The aim of this study was to clarify the oral microflora characteristics of pSS patients and to reveal the connection between oral bacterial composition and dental caries using a high-throughput sequencing technique. METHODS: Thirty-five pSS patients and 20 healthy controls were enrolled in this study...
April 11, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38598024/elevated-serum-25-hydroxyvitamin-d-a-potential-indicator-of-remission-in-takayasu-arteritis-patients-with-normal-esr-and-crp-levels
#3
JOURNAL ARTICLE
Hua Liao, Juan Du, Fengjuan Li, Shiyu Yang, Guanming Qi, Lili Pan
OBJECTIVE: The goal of the present study was to investigate the correlation between serum 25-hydroxyvitamin D [25(OH)D] levels and disease remission in Takayasu arteritis (TAK) patients. METHODS: This retrospective study included 59 patients in the study group and 80 patients in the validation cohort with TAK. After 6 months of therapy, patients were re-evaluated, and serum 25(OH)D levels were compared before and after treatment. Correlations between changes in 25(OH)D levels and changes in disease activity scores (NIH, ITAS2010, ITAS...
April 10, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38594463/latent-class-analysis-of-psychological-resilience-and-influencing-factors-in-patients-with-rheumatoid-arthritis-a-cross-sectional-survey
#4
JOURNAL ARTICLE
Jian Zhou, Yuqin Gan, Xinxin Fan, Hong Qi, Yuqiong Cao, Zongting Luo
OBJECTIVES: To investigate the latent class of psychological resilience in patients with rheumatoid arthritis (RA) and examine the factors influencing various latent types. METHODS: A cross-sectional survey design was used in this study. A total of 480 patients with RA were enrolled from two tertiary care institutions in Chengdu, Sichuan Province, between May and November 2023, using the convenience sample approach. The General Information Questionnaire, CD-RISC-10, SSRS, ASES-8, and BRAF-MDQ were used to analyze the latent classes of psychological resilience in the respondents, and the factors influencing the latent classes were explored using one-way analysis of variance, analysis of variance, and multi-categorical logistic regression analysis...
April 10, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38587715/an-externally-validated-clinical-laboratory-nomogram-for-myocardial-involvement-in-adult-idiopathic-inflammatory-myopathy-patients
#5
JOURNAL ARTICLE
Junyu Liang, Liyan Wan, Yake Yao, Xiao Cui, Ye He, Shuangshuang Li, Mengdi Jiang, Yiduo Sun, Heng Cao, Jin Lin
OBJECTIVES: This study aimed at identifying clinical and laboratory risk factors for myocardial involvement (MI) in idiopathic inflammatory myopathies (IIMs) patients as well as constructing a risk-predicted nomogram for prediction and early identification of MI. METHODS: An IIMs cohort in southeastern China was constructed, including 504 adult IIMs patients who met the inclusion and exclusion criteria, and were hospitalized at four divisions of the First Affiliated Hospital, Zhejiang University School of Medicine from January 1st 2018 to April 30st 2022...
April 8, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38584198/hematological-indices-in-psoriatic-enthesopathy-relation-to-clinical-and-ultrasound-evaluation
#6
JOURNAL ARTICLE
Arwa S Amer, Ahmed Y Al Shambaky, Seham G Ameen, Amira Khalil Sobih
BACKGROUND: Enthesopathy is considered a crucial aspect of assessment and outcome in psoriatic arthritis (PsA). Musculoskeletal ultrasound (MSUS) is a critical tool for accurately detecting enthesitis. Recent research focuses on identifying simple biomarkers for detecting and monitoring psoriatic enthesopathy. Red cell distribution width (RDW), mean platelet volume (MPV), and neutrophil/lymphocyte ratio (NLR) are components of a complete blood count (CBC) and are reliable bio-inflammatory markers in various rheumatic diseases...
April 8, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38581577/letter-to-the-editor-development-and-validation-of-equations-for-conversion-from-das28esr-and-das28crp-to-the-sdai-in-patients-with-rheumatoid-arthritis
#7
LETTER
Tianfei Yu, Siyuan Qian, Ming Li
No abstract text is available yet for this article.
April 6, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38578510/non-thyroidal-disease-syndrome-in-patients-with-systemic-lupus-erythematosus-relation-to-disease-inflammatory-activity
#8
JOURNAL ARTICLE
Xue Meng, Ang Lv, Mulin Tang, Xue Liu, Xinhui Wang, Yuchen Li, Yuwei Chai, Qingqing Yang, Chunjia Kou, Li Zhang, Ming Li, Haiqing Zhang
OBJECTIVE: To identify risk factors for the development of non-thyroidal illness syndrome (NTIS) in patients with systemic lupus erythematosus (SLE). METHODS: A retrospective analysis of 517 SLE patients and 1034 age-and sex-matched healthy population was conducted to compare the prevalence of NTIS in these two groups, and to analyze the laboratory and clinical characteristics of SLE patients with NTIS. Finally Logistic regression analysis was used to determine the risk factors for NTIS in SLE patients...
April 5, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38573481/functional-capacity-physical-activity-and-arterial-stiffness-in-patients-with-systemic-sclerosis
#9
JOURNAL ARTICLE
Aylin Tanriverdi, Buse Ozcan Kahraman, Nazenin Hande Sezgin, Yesim Erez, Serap Acar, Ahmet Merih Birlik, Ebru Ozpelit, Sema Savci
OBJECTIVES: Systemic sclerosis (SSc) is a complex immune-mediated connective tissue disease, involving skin manifestations, vascular features, and organ-based complications that may affect functional capacity and physical activity. Functional capacity and physical activity are associated with arterial stiffness; however, this relationship has not been evaluated in patients with SSc. Therefore, the objective of this study was to investigate the association of functional capacity and physical activity with arterial stiffness in patients with SSc...
April 4, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38573480/geiser-sign-in-a-patient-with-rheumatoid-arthritis
#10
EDITORIAL
Daniela Oliveira, Raquel Miriam Ferreira, Carlos Marques Gomes, Carlos Vaz
No abstract text is available yet for this article.
April 4, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38573479/divergent-perspectives-exploring-the-relationships-between-st-george-s-respiratory-questionnaire-and-outcome-measures-in-systemic-sclerosis-associated-interstitial-lung-disease
#11
JOURNAL ARTICLE
Enes Basaran, Duygu Temiz Karadag, Ozgur Cakir, Neslihan Gokcen, Ayten Yazici, Ayse Cefle
INTRODUCTION/OBJECTIVES: Controversy exists regarding the concordance of patient-reported outcome measures (PROMs) with other assessment parameters in systemic sclerosis-associated interstitial lung disease (SSc-ILD). This study aims to explore the association between the St. George's Respiratory Questionnaire (SGRQ) and various outcome measures in patients with SSc-ILD within a real-world cross-sectional setting. METHOD: Patients with SSc-ILD were consecutively recruited from our SSc cohort...
April 4, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38568436/non-invasive-imaging-for-predicting-labial-salivary-gland-biopsy-outcomes-in-patients-with-suspected-primary-sj%C3%A3-gren-syndrome
#12
JOURNAL ARTICLE
Nan Xu, Xuanhan Wang, Tiantian Dai, Nianxing Liu, Yimin Ding, Jinqiong Chen, Longlong Tian, Yuxuan Fang, Yongbin Zhang, Guoqing Li
To identify the value of salivary gland ultrasound (SGUS) combined with magnetic resonance imaging (MRI) and magnetic resonance sialography (MRS) in predicting the results of labial salivary gland biopsy (LSGB) in patients with suspected primary Sjögren syndrome (pSS), and construct a nomogram model to predict LSGB results. A total of 181 patients who were admitted with suspected pSS from December 2018 to April 2023 were examined and divided into a training set (n = 120) and a validation set (n = 61)...
April 3, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38565803/a-predictive-model-for-premature-atherosclerosis-in-systemic-lupus-erythematosus-based-on-clinical-characteristics
#13
JOURNAL ARTICLE
Ruyu Liang, Haojie Xu, Ranran Yao, Wenwen Pei, Ziye Wang, Renge Liang, Xiao Han, Yunshan Zhou, Yuan An, Yin Su
OBJECTIVE: Systemic lupus erythematosus (SLE) is associated with a significant risk of atherosclerotic cardiovascular disease, especially in the development of premature atherosclerosis. Specific prediction models for premature atherosclerosis in SLE patients are still limited. The objective of this study was to establish a predictive model for premature atherosclerosis in SLE. METHOD: The study collected clinical and laboratory data from 148 SLE patients under the age of 55, between January 2021 and June 2023...
April 2, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38563865/frequency-and-the-effects-of-spondyloarthritis-spectrum-disorders-on-the-clinical-course-and-management-of-takayasu-arteritis-an-observational-retrospective-study
#14
JOURNAL ARTICLE
Kerem Abacar, Sema Kaymaz-Tahra, Özün Bayındır, Burak İnce, Muhammet Emin Kutu, Ayten Yazıcı, Elif Durak Ediboğlu, Tuba Demirci-Yıldırım, Zeliha Ademoğlu, Ahmet Omma, Nazife Şule Yaşar-Bilge, Gezmiş Kimyon, Timuçin Kaşifoğlu, Hakan Emmungil, Fatoş Önen, Servet Akar, Ayşe Cefle, Nilüfer Alpay-Kanıtez, Selda Çelik, Murat İnanç, Kenan Aksu, Gökhan Keser, Haner Direskeneli, Fatma Alibaz-Öner
OBJECTIVES: Extravascular findings of Takayasu arteritis (TAK) often share features with the spondyloarthritis (SpA) spectrum of disorders. However, the characteristics of this overlap and its effect on the vascular manifestations of TAK are not fully known. Therefore, we aimed to investigate the frequency of SpA-related features in TAK patients. MATERIAL AND METHODS: In this observational retrospective study, 350 patients with TAK classified according to ACR 1990 criteria, from 12 tertiary rheumatology clinics, were included and evaluated for the presence of axSpA, IBD, or psoriasis...
April 2, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38561590/gardening-yardwork-in-people-with-knee-osteoarthritis-is-not-associated-with-symptom-or-structural-progression-over-48%C3%A2-months-data-from-the-osteoarthritis-initiative
#15
JOURNAL ARTICLE
Grace H Lo, Julieann C Patarini, Michael J Richard, Timothy E McAlindon, Andrea M Kriska, Bonny Rockette-Wagner, Charles B Eaton, Marc C Hochberg, C Kent Kwoh, Michael C Nevitt, Jeffrey B Driban
OBJECTIVE: To evaluate the relationship of gardening/yardwork with symptomatic and structural progression in those with pre-existing radiographic knee osteoarthritis (OA) in the Osteoarthritis Initiative (OAI), an observational study designed to evaluate potential and known biomarkers and risk factors of knee OA. METHODS: We conducted a cohort study nested within the OAI, including participants ≥ 50 years old with radiographic OA in at least one knee at the time of OAI enrollment...
April 1, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38538907/the-value-of-mri-based-radiomics-for-evaluating-early-parotid-gland-injury-in-primary-sj%C3%A3-gren-s-syndrome
#16
JOURNAL ARTICLE
Lu Lu, Tiantian Dai, Yi Zhao, Hang Qu, Qi An Sun, Hongyi Xia, Wei Wang, Guoqing Li
OBJECTIVE: This study aimed to evaluate the value of machine learning models (ML) based on MRI radiomics in diagnosing early parotid gland injury in primary Sjögren's syndrome (pSS). METHODS: A total of 164 patients (114 in the training cohort and 50 in the testing cohort) with pSS (n=82) or healthy controls (HC) (n=82) were enrolled. Itksnap software was used to perform two-dimensional segmentation of the bilateral parotid glands on T1-weighted (T1WI) and fat-suppressed T2-weighted imaging (fs-T2WI) images...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38536518/prognostic-modeling-in-early-rheumatoid-arthritis-reconsidering-the-predictive-role-of-disease-activity-scores
#17
JOURNAL ARTICLE
Alix Bird, Lauren Oakden-Rayner, Luke A Smith, Minyan Zeng, Shonket Ray, Susanna Proudman, Lyle J Palmer
OBJECTIVE: In this prospective cohort study, we provide several prognostic models to predict functional status as measured by the modified Health Assessment Questionnaire (mHAQ). The early adoption of the treat-to-target strategy in this cohort offered a unique opportunity to identify predictive factors using longitudinal data across 20 years. METHODS: A cohort of 397 patients with early RA was used to develop statistical models to predict mHAQ score measured at baseline, 12 months, and 18 months post diagnosis, as well as serially measured mHAQ...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38536517/development-and-validation-of-a-risk-prediction-model-for-valve-regurgitation-in-beh%C3%A3-et-s-disease
#18
JOURNAL ARTICLE
Zixian Deng, Benhui Liang, Tangzhiming Li, Qiyun Liu, Xiaoyu Wang, Xin Sun, Ziwei Ou, Lin Zhao, Cong Xu, Huadong Liu, Jianghua Li
BACKGROUND: In Behçet's disease (BD), mild-to-severe valvular regurgitation (VR) poses a serious complication that contributes significantly to heart failure and eventually death. The accurate prediction of VR is crucial in the early stages of BD subjects for improved prognosis. Accordingly, this study aimed to develop a nomogram that can detect VR early in the course of BD. METHODS: One hundred seventy-two patients diagnosed with Behçet's disease (BD) were conducted to assess cardiac valve regurgitation as the primary outcome...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38517652/efficacy-and-safety-of-tofacitinib-for-chronic-plaque-psoriasis-and-psoriatic-arthritis-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
JOURNAL ARTICLE
Qianqian Dai, Yanfeng Zhang, Qian Liu, Chijin Zhang
OBJECTIVES: To summarize and analyze the results of published randomized controlled trials of tofacitinib for the treatment of chronic plaque psoriasis and psoriatic arthritis(PsA) and discuss its efficacy and safety. PATIENTS AND METHODS: An exhaustive systematic search encompassing PubMed, Cochrane, Embase, and Web of Science databases was conducted up to July 2023. Studies eligible for inclusion were analyzed, organized using Review Manager version 5.4.1 (Cochrane Collaboration, Oxford, UK) and STATA 15...
March 22, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38517651/how-can-clinicians-enhance-self-efficacy-beliefs-in-osteoarthritis-an-overview-of-systematic-reviews-with-meta-analysis
#20
REVIEW
Javier Martinez-Calderon, Francisco Javier Cano-García, Cristina García-Muñoz, Carmen Rufo-Barbero, Javier Matias-Soto, Marta Infante-Cano
This overview of reviews aimed to synthesize the effectiveness of non-pharmacological approaches to enhance self-efficacy in people with osteoarthritis. The CINAHL, Embase, PsycINFO, PubMed, SPORTDiscus, and the Cochrane Library databases were searched from inception to December 2023. We considered systematic reviews with meta-analysis of randomized clinical trials evaluating any non-pharmacological intervention. We used AMSTAR 2 to assess the methodological quality of reviews. The overlap between reviews was calculated...
March 22, 2024: Clinical Rheumatology
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