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Rheumatology International

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https://read.qxmd.com/read/30756137/role-of-inflammation-in-the-pathogenesis-and-treatment-of-fibromyalgia
#1
REVIEW
Ilke Coskun Benlidayi
Fibromyalgia is a multifaceted disease. The clinical picture of fibromyalgia covers numerous comorbidities. Each comorbidity stands as a distinct condition. However, common pathophysiologic factors are occupied in their background. Along with the genetic, environmental and neuro-hormonal factors, inflammation has been supposed to have role in the pathogenesis of fibromyalgia. The aim of the present article was to review the current literature regarding the potential role of inflammation in the pathogenesis and treatment of fibromyalgia...
February 13, 2019: Rheumatology International
https://read.qxmd.com/read/30747253/hand-grip-endurance-moderating-the-effect-of-grip-force-on-functional-ability-and-disease-activity-in-rheumatoid-arthritis-patients-a-cross-sectional-study
#2
Ines Doko, Žarko Bajić, Amir Dubravić, Merita Qorolli, Simeon Grazio
To examine the effect of endurance on the relationship between grip force and measures of functional capacity and disease activity, we performed a cross-sectional study at the University Department of Rheumatology, Physical medicine and Rehabilitation from January 2017 to August 2018. Functional capacity of the hand was measured by ABILHAND-RA questionnaire and disease activity was assessed by the Disease Activity Score (DAS-28-CRP). All participants underwent dynamometric measurements of maximal grip force and hand grip endurance during repeated gripping...
February 12, 2019: Rheumatology International
https://read.qxmd.com/read/30725156/real-world-evidence-in-rheumatic-diseases-relevance-and-lessons-learnt
#3
REVIEW
Durga Prasanna Misra, Vikas Agarwal
An emerging trend in the medical literature, including the Rheumatology literature, is that of accumulating large, multicentric, multi-national data based on registries of patients seen in real life situations. Such real-world evidence (RWE) may help provide valuable insights into the long-term outcomes of disease in unselected patients seen in daily practice, including patients belonging to vulnerable populations such as extremes of age, during pregnancy and lactation. Evidences gathered from real life practice settings can help understand drug prescription patterns, including adherence to treatment guidelines, cost-effectiveness of therapy, and real-life long-term outcomes, and adverse effects of treatment with particular medications...
February 6, 2019: Rheumatology International
https://read.qxmd.com/read/30721326/correction-to-on-drug-and-drug-free-remission-by-baseline-symptom-duration-abatacept-with-methotrexate-in-patients-with-early-rheumatoid-arthritis
#4
Vivian P Bykerk, Gerd R Burmester, Bernard G Combe, Daniel E Furst, Tom W J Huizinga, Harris A Ahmad, Paul Emery
The article "On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis", written by Vivian P.Bykerk, was originally published Online First without open access.
February 5, 2019: Rheumatology International
https://read.qxmd.com/read/30706192/clinical-significance-of-ocular-manifestations-in-granulomatosis-with-polyangiitis-association-with-sinonasal-involvement-and-damage
#5
Andrea Hinojosa-Azaola, Annette García-Castro, Alejandra Juárez-Flores, Claudia Recillas-Gispert
Ocular involvement is present in 50-60% of granulomatosis with polyangiitis (GPA) patients and can affect any part of the ocular globe. The present study describes ophthalmologic manifestations, association with systemic symptoms, disease activity and damage in GPA. A cross-sectional study was conducted including patients with GPA who underwent rheumatologic and ophthalmologic evaluation. Demographics, comorbidities, ophthalmologic symptoms, serologic markers, radiographic studies, disease activity and damage were assessed...
January 31, 2019: Rheumatology International
https://read.qxmd.com/read/30689015/characteristics-of-individual-thigh-muscles-including-cross-sectional-area-and-adipose-tissue-content-measured-by-magnetic-resonance-imaging-in-knee-osteoarthritis-a-cross-sectional-study
#6
Koun Yamauchi, Chisato Kato, Takayuki Kato
This study aimed to identify the parameters related to the area and adipose tissue content of thigh muscles that are associated with radiographic knee osteoarthritis grade. Fifty patients (mean age ± standard deviation, 73.0 ± 4.5 years) were divided into early osteoarthritis (n = 23) and established osteoarthritis (n = 27) groups based on Kellgren-Lawrence classification. The femorotibial angle was measured from anteroposterior radiographs of the lower limbs. Individual thigh muscle and adipose tissue areas were analyzed using axial T1-weighted magnetic resonance imaging...
January 28, 2019: Rheumatology International
https://read.qxmd.com/read/30684041/time-until-onset-of-action-when-treating-psoriatic-arthritis-meta-analysis-and-novel-approach-of-generating-confidence-intervals
#7
REVIEW
Phuong Anh Pham, Corinna Dressler, Lisa Eisert, Alexander Nast, Ricardo Niklas Werner
Psoriatic arthritis (PsA) is associated with progressive joint destruction and reduced quality of life. The time until a drug treatment starts to show an effect (TOA) is important for preventing joint destruction. The objective was to assess the time until onset of action of drugs when treating PsA. A systematic review of PsA drug trials was performed. Outcomes were: time until 25% of patients (TOA) reached (1) ≥ 20%, (2) ≥ 50% improvement in modified American College of Rheumatology response criteria (ACR), (3) ≥ 75% reduction in Psoriasis Area and Severity Index (PASI75)...
January 25, 2019: Rheumatology International
https://read.qxmd.com/read/30680511/the-association-of-cat-262c-t-polymorphism-with-catalase-activity-and-treatment-response-in-juvenile-idiopathic-arthritis
#8
Jelena Bašić, Jelena Vojinović, Tatjana Jevtović-Stoimenov, Milena Despotović, Tatjana Cvetković, Dragana Lazarević, Gordana Sušić, Vuk Milošević, Mina Cvetković, Dušica Pavlović
Oxidative stress is believed to be of great importance for both the etiology and the persistence of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the association of -262C/T polymorphism of the catalase (CAT) gene with JIA, as well as to evaluate whether this polymorphism can influence plasma CAT activity and outcome in JIA patients treated with etanercept. A total of 154 subjects (60 JIA patients and 94 healthy volunteers) were screened for CAT-262C/T gene polymorphism using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method...
January 24, 2019: Rheumatology International
https://read.qxmd.com/read/30673815/infliximab-associated-focal-segmental-glomerulosclerosis-in-a-patient-with-ankylosing-spondylitis
#9
REVIEW
Handan Yarkan Tuğsal, Berrin Zengin, Gökçe Kenar, Gerçek Can, Mehtat Ünlü, Fatoş Önen, Merih Birlik
The introduction of tumor necrosis factor-alpha (TNF-α)-targeting drugs has given new opportunities in the treatment of various inflammatory rheumatic diseases and has been the most important development in the treatment of spondyloarthritis (SpA). However, the increasing use and longer follow-up periods of treatment also pose risks of developing various adverse effects ranging from common ones including infections to uncommon renal complications. This report describes a case of infliximab-induced focal segmental glomerulosclerosis (FSGS) in a 40-year-old female patient with ankylosing spondylitis (AS) who presented with asymptomatic proteinuria and microscopic hematuria...
January 23, 2019: Rheumatology International
https://read.qxmd.com/read/30671597/hand-and-knee-osteoarthritis-are-associated-with-reduced-diameters-in-retinal-vessels-the-ages-reykjavik-study
#10
Helgi Jonsson, Diana E Fisher, Gudny Eiriksdottir, Thor Aspelund, Ronald Klein, Vilmundur Gudnason, Mary Frances Cotch
To investigate the association between osteoarthritis (OA) and microvascular pathology, we examined the relationship between retinal microvascular caliber and osteoarthritis of the hand and knee in an elderly population. The AGES-Reykjavik is a population-based, multidisciplinary longitudinal cohort study of aging. Retinal vessel caliber, hand osteoarthritis and total knee joint replacements due to OA were examined in 4757 individuals (mean age 76 ± 5 years; 57% female). Incident knee joint replacements during 5-year follow-up (n = 2961, mean age 75 ± 5 years; 58% female) were also assessed...
January 22, 2019: Rheumatology International
https://read.qxmd.com/read/30656412/secular-trends-in-the-incidence-and-prevalence-of-rheumatoid-arthritis-within-members-of-an-integrated-health-care-delivery-system
#11
Aniket A Kawatkar, Sherine E Gabriel, Steven J Jacobsen
The study objective was to estimate secular trends in the overall incidence rate (IR) and prevalence rate (PR) of rheumatoid arthritis (RA); and subgroup-specific IR and PR by race, ethnicity, and sex in a multi-ethnic population of a large integrated health care delivery system. An ecological study was conducted within the adult population of Kaiser Permanente Southern California health plan. From January 1995 up to and including December 2014, annual IR and PR were calculated separately by race, ethnicity, sex and pooled overall...
January 17, 2019: Rheumatology International
https://read.qxmd.com/read/30649569/level-of-adherence-to-prescribed-exercise-in-spondyloarthritis-and-factors-affecting-this-adherence-a-systematic-review
#12
REVIEW
M T McDonald, S Siebert, E H Coulter, D A McDonald, L Paul
Adherence is a primary determinant of the effectiveness of any intervention. Exercise is considered essential in the management of spondyloarthritis (SpA); however, the overall adherence to exercise programmes and factors affecting adherence are unknown. The aim of this systematic review was to examine measures of, and factors influencing adherence to, prescribed exercise programmes in people with SpA. A search was performed in August 2018 using five data bases; the Cochrane library, CINAHL, EMBASE, MEDLINE, and Web of Science Collections...
January 16, 2019: Rheumatology International
https://read.qxmd.com/read/30617512/determination-of-magnetic-resonance-imaging-criteria-for-diagnosis-of-adhesive-capsulitis
#13
Jae Hoon Jung, Du Hwan Kim, Jaehyuck Yi, Du-Han Kim, Chul-Hyun Cho
The objective of this study was to identify optimal magnetic resonance imaging (MRI) parameters and their cutoff values for diagnosing adhesive capsulitis (AC). One hundred shoulder MRI images with stage 2 AC (AC group) and 100 MRI images without AC (control group) were randomly reviewed by two experienced shoulder specialists. They were asked whether MRI findings were compatible with AC and measurement of MRI parameters. Sensitivity, specificity, and accuracy were calculated. Correlation between MRI parameters and the range of motions was also analyzed...
January 7, 2019: Rheumatology International
https://read.qxmd.com/read/30612148/idiopathic-hip-chondrolysis-a-case-report-of-a-caucasian-hla-b27-positive-adolescent-with-a-history-of-long-walking
#14
REVIEW
Khaled T Kampani, Dimitrios V Papadopoulos, Andreas G Tsantes, Anna Batistatou, Aristotelis Fylaktos, Christos D Papageorgiou
Idiopathic hip chondrolysis is a rare disorder, the pathophysiology of which has not been fully elucidated. Several theories have been proposed regarding the cause of the disease with some of them involving autoimmune-mediated cartilage destruction. There are several similar features between idiopathic hip chondrolysis and rheumatologic diseases such as juvenile idiopathic arthritis, so whether these two disorders are different or not is still debatable. This case report aims to help comprehending this complex disorder by presenting a case of idiopathic hip chondrolysis with apparent risk factors, such as repetitive microtrauma and presence of HLA-B27 antigens...
January 5, 2019: Rheumatology International
https://read.qxmd.com/read/30604206/pediatric-rheumatology-in-turkey
#15
REVIEW
Amra Adrovic, Ozgur Kasapcopur
Pediatric Rheumatology is an emerging specialty in Turkey with increasing number of available centers and specialists all over the country. In this paper, we sought to provide an overview on pediatric rheumatology service in our country, as well as to assess the principle published literature from Turkey in this field. A systematic literature search has been performed to achieve the significance and the impact of this manuscript. The most relevant used databases (PubMed/MEDLINE, Web of Science, SCOPUS) for peer-reviewed studies and reviews in English language published during the last 5 years were screened...
January 3, 2019: Rheumatology International
https://read.qxmd.com/read/30604205/efficacy-and-safety-of-long-term-treatment-with-intravenous-colchicine-for-familial-mediterranean-fever-fmf-refractory-to-oral-colchicine
#16
Chagai Grossman, Itzhak Farberov, Olga Feld, Avi Livneh, Ilan Ben-Zvi
Colchicine is the mainstay of treatment for familial Mediterranean fever (FMF). Intravenous (IV) colchicine, administered over several months, has been shown to be effective for FMF patients unresponsive to oral colchicine. The objective of this study was to evaluate the efficacy and safety of long-term IV colchicine treatment in oral colchicine-resistant FMF. We analyzed data of 15 patients with frequent FMF attacks, despite a maximal tolerated dose of oral colchicine (2-3 mg/day), who were treated with weekly IV injections of 1 mg of colchicine for at least 12 months...
January 2, 2019: Rheumatology International
https://read.qxmd.com/read/30604204/supervised-walking-improves-cardiorespiratory-fitness-exercise-tolerance-and-fatigue-in-women-with-primary-sj%C3%A3-gren-s-syndrome-a-randomized-controlled-trial
#17
Samira Tatiyama Miyamoto, Valéria Valim, Luciana Carletti, Wan-Fai Ng, Anselmo José Perez, Dennis William Lendrem, Michael Trennel, Raquel Altoé Giovelli, Laiza Hombre Dias, Érica Vieira Serrano, Alice Mendonça Subtil, Vanessa Cândido Abreu, Jamil Natour
OBJECTIVE: The aim of this study was to evaluate the safety and effectiveness of a supervised walking program in women with primary Sjögren's syndrome (pSS). METHODS: Forty-five sedentary women fulfilling the American European Consensus Criteria for pSS were randomized to a training group (TG, n = 23) or control group (CG, n = 22). Patients in the TG were submitted to supervise walking three times a week for 16 weeks. The patients of the CG were instructed to not perform any kind of regular physical exercise...
January 2, 2019: Rheumatology International
https://read.qxmd.com/read/30604203/reliability-of-real-world-data
#18
Ilke Coskun Benlidayi
No abstract text is available yet for this article.
January 2, 2019: Rheumatology International
https://read.qxmd.com/read/30600343/early-outcomes-in-kidney-transplant-recipients-with-systemic-lupus-erythematosus
#19
Jorge Mario López-Morales, Lauro Quintanilla-González, Juan Carlos Ramírez-Sandoval, Andrea Hinojosa-Azaola
Kidney transplant (KT) is the best treatment for patients who progress to end-stage renal disease. Short-term outcomes in patients with systemic lupus erythematosus (SLE) following KT are not well known. To describe the postoperative outcomes and complications in SLE patients undergoing KT, we conducted a case-control study from 2010 to 2015 including SLE recipients compared to non-SLE controls matched by age and sex. Demographics, comorbidities, donor characteristics, and preoperative tests were retrieved...
January 2, 2019: Rheumatology International
https://read.qxmd.com/read/30600342/dietary-protein-intake-and-upper-leg-muscle-strength-in-subjects-with-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#20
A H de Zwart, M van der Leeden, L D Roorda, M Visser, M van der Esch, W F Lems, J Dekker
The aims of this study were (1) to describe dietary protein intake, and (2) to evaluate the association between dietary protein intake and upper leg muscle strength in subjects with knee osteoarthritis (OA). Baseline data from the OA was used, in a cross-sectional study. All subjects were diagnosed with symptomatic and radiographic knee OA. Daily dietary protein intake was measured with the Block Brief 2000 food frequency questionnaire (g/kg body weight). The sum of knee flexion and extension strength of the index knee (N/kg bodyweight) was assessed with the Good Strength chair test...
January 2, 2019: Rheumatology International
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