journal
https://read.qxmd.com/read/38051374/serum-il-17-and-tnf%C3%AE-as-prognostic-biomarkers-in-systemic-sclerosis-patients-a-prospective-study
#1
JOURNAL ARTICLE
Joanna Kosałka-Węgiel, Sabina Lichołai, Renata Pacholczak-Madej, Sylwia Dziedzina, Mamert Milewski, Piotr Kuszmiersz, Anna Korona, Jolanta Gąsior, Aleksandra Matyja-Bednarczyk, Helena Kwiatkowska, Lech Zaręba, Andżelika Siwiec-Koźlik, Paweł Koźlik-Siwiec, Anita Wach, Weronika Pociej-Marciak, Marek Sanak, Jacek Musiał, Stanisława Bazan-Socha, Mariusz Korkosz
Recent reports have demonstrated that endothelial injury is critical in the pathogenesis of systemic sclerosis (SSc) and is associated with increased levels of circulating inflammatory biomarkers. This study aims to analyze the serum concentrations of selected cytokines and evaluate their relationship with SSc clinics and the long-term course of the disease. This study included 43 SSc patients and 24 matched healthy controls. In both groups, we measured serum levels of inflammatory cytokines related to the inflammatory response, such as tumor necrosis factor (TNF)α, interferon (IFN)γ, interleukin (IL)-4, IL-6, IL-10, and IL-17, and fibroblast activation protein (FAP)...
December 5, 2023: Rheumatology International
https://read.qxmd.com/read/38030947/quality-of-reporting-and-nature-of-harms-in-clinical-trials-on-supervised-exercise-in-patients-with-rheumatoid-arthritis-or-axial-spondyloarthritis
#2
Max M H Teuwen, Thea P M Vliet Vlieland, Salima F E van Weely, Jan W Schoones, Anne-Kathrin Rausch Osthoff, Carsten B Juhl, Karin Niedermann, Maaike G J Gademan, Cornelia H M van den Ende
To describe the quality of reporting and the nature of reported harms in clinical studies on the effectiveness of supervised exercises in patients with rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA). We performed a systematic review, searching eight databases up to February 2023. Randomized controlled trials (RCTs) evaluating supervised exercises in adults with RA or axSpA were considered eligible. Data on harms were extracted according to the CONSORT Harms 2022 Checklist. Among others, it was recorded if harms were prespecified or non-prespecified...
November 30, 2023: Rheumatology International
https://read.qxmd.com/read/38006457/functional-limitations-of-people-with-rheumatoid-arthritis-or-axial-spondyloarthritis-and-severe-functional-disability-a-cross-sectional-descriptive-study
#3
JOURNAL ARTICLE
Max M H Teuwen, Salima F E van Weely, Thea P M Vliet Vlieland, Thom Douw, Dirkjan van Schaardenburg, Alfons A den Broeder, Astrid M van Tubergen, Maria A T van Wissen, Cornelia H M van den Ende, Maaike G J Gademan
The objective of the study is to describe the nature of functional limitations in activities and participation in people with Rheumatoid Arthritis (RA) or axial SpondyloArthritis (axSpA) with severe functional disability. Baseline data from people with RA (n = 206) or axSpA (n = 155) and severe functional disability participating in an exercise trial were used. Their three most limited activities were derived from the Patient Specific Complaint (PSC) instrument and linked to the International Classification of Functioning and Health (ICF)...
November 25, 2023: Rheumatology International
https://read.qxmd.com/read/37999798/musculoskeletal-disorders-and-pain-in-agricultural-workers-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis
#4
JOURNAL ARTICLE
Mrithula Shivakumar, Victoria Welsh, Ram Bajpai, Toby Helliwell, Christian Mallen, Michelle Robinson, Thomas Shepherd
Agricultural workers constitute two-thirds of the population of Low- and Middle-Income Countries (LMIC) and are at increased risk of developing musculoskeletal disorders (MSD) due to high-risk activities. This systematic review and meta-analysis aim to synthesise the prevalence, predictors, and outcomes of musculoskeletal pain amongst agricultural workers to identify priority areas for prevention and development of early interventions. This systematic review and meta-analysis included Studies published from the inception of global electronic databases until 30 September 2022 were included...
November 24, 2023: Rheumatology International
https://read.qxmd.com/read/37999797/healing-refractory-livedoid-vasculopathy-related-skin-ulcers-by-ozone-therapy-a-case-based-review
#5
REVIEW
Gulsah Yasa Ozturk, Burhan Fatih Kocyigit
Chronic skin wounds represent a prominent etiological factor in the occurrence of non-traumatic foot amputations on a global scale and pose a substantial threat to the patient's well-being and mortality in the absence of effective treatment strategies. There exists a subset of patients that exhibit an insufficient response to different treatment options, comprising antibiotics, dressings, gauze bandages, debridement, rehabilitation, collagen patch, and vacuum-assisted closure. In this patient group, distinct treatment strategies emerge before surgery and amputation...
November 24, 2023: Rheumatology International
https://read.qxmd.com/read/37987842/kidney-histopathology-in-predicting-flares-following-drug-withdrawal-in-proliferative-lupus-nephritis-in-clinical-remission
#6
JOURNAL ARTICLE
Aishwarya Gopal, Chengappa Kavadichanda, Mohan Sreelekha Gayathri, Mamatha Gorijavolu, Devender Bairwa, Christina Mary Mariaselvam, Bheemanathi Hanuman Srinivas, Molly Mary Thabah, Vir Singh Negi
Residual renal histopathological activity at clinical remission in Proliferative Lupus Nephritis (PLN) can predict renal flare upon immunosuppression withdrawal. Data on the role of histological renal remission in predicting extra-renal flares is lacking. We assessed renal histopathology prior to drug withdrawal and the occurrence of renal and extra-renal flares over 52 weeks after drug withdrawal in PLN patients in long-term clinical remission. This is a subgroup analysis of a non-inferiority, open-label randomized (1:1) controlled trial...
November 21, 2023: Rheumatology International
https://read.qxmd.com/read/37985499/jak-inhibitors-improve-atp-production-and-mitochondrial-function-in-rheumatoid-arthritis-a-pilot-study
#7
JOURNAL ARTICLE
Valentina Mihaylova, Maria Kazakova, Zguro Batalov, Rositsa Karalilova, Anastas Batalov, Victoria Sarafian
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease associated by inflammation of the synovial tissue and autoantibody production. Oxidative stress and free radicals are known to be indirectly implicated in joint damage and cartilage destruction in RA. Several studies describe the presence of mitochondrial dysfunction in RA, but few of them follow the dynamics in energy parameters after therapy. The aim of our investigation is to evaluate the direct effect of JAK inhibitors on cellular metabolism (and under induced oxidative stress) in RA patients...
November 20, 2023: Rheumatology International
https://read.qxmd.com/read/37978075/peripheral-and-ocular-microvascular-alterations-in-systemic-sclerosis-observations-from-capillaroscopic-assessments-perfusion-peripheral-analysis-and-optical-coherence-tomography-angiography
#8
JOURNAL ARTICLE
Carlo Alberto Cutolo, Andrea Cere, Paola Toma, Tommaso Cannavacciuolo, Chiara Toma, Serena Balito, Veronica Gerli, Vanessa Smith, Alberto Sulli, Sabrina Paolino, Emanuele Gotelli, Carlo Enrico Traverso, Massimo Nicolò, Maurizio Cutolo, Elvis Hysa
To investigate the correlations between finger microvascular morphology and function in patients with systemic sclerosis (SSc) and the status of ocular microcirculation, as detected by nailfold videocapillaroscopy (NVC), laser speckle contrast analysis (LASCA), and optical coherence tomography angiography (OCTA). The enrollment included 32 SSc patients, classified according to the 2013 ACR/EULAR criteria, and 27 sex- and age-matched healthy controls. The participants underwent comprehensive rheumatological and ophthalmological examinations, as well as NVC, LASCA, and OCTA analysis on the same day at a single center from March to October 2022...
November 17, 2023: Rheumatology International
https://read.qxmd.com/read/37925382/scleromalacia-perforans-as-an-early-manifestation-of-late-onset-rheumatoid-arthritis-a-case-based-review
#9
REVIEW
Letícia Queiroga de Figueiredo, Fernanda Oliveira de Andrade Lopes, André Silva Franco, Henrique Ayres Mayrink Giardini, Lissiane Karine Noronha Guedes, Karina Rossi Bonfiglioli, Andrea Yukie Shimabuco, Ana Cristina de Medeiros Ribeiro, Diogo Souza Domiciano
Rheumatoid arthritis is a chronic autoimmune disease that can affect different organs beyond the joints. Ocular involvement includes keratoconjunctivitis sicca, peripheral ulcerative keratitis (PUK), episcleritis, scleritis, anterior uveitis, and corneal impairment. The most severe form of scleritis, scleromalacia perforans, is an aggressive ophthalmic manifestation that can potentially lead to blindness, usually occurring in late stages of disease. We report a case of an elderly woman in which this severe ocular manifestation occurred early on disease onset, differing from most of the previously reported cases of scleromalacia perforans...
November 4, 2023: Rheumatology International
https://read.qxmd.com/read/37917336/hyperthyroidism-is-an-important-risk-factor-for-incident-gout-particularly-in-younger-age-groups-and-males
#10
LETTER
Yunwen Tao, Changyan Xu, Chen Fang
No abstract text is available yet for this article.
November 2, 2023: Rheumatology International
https://read.qxmd.com/read/37907642/exercise-therapy-for-improving-cardiovascular-health-in-rheumatoid-arthritis
#11
REVIEW
Ilke Coskun Benlidayi
There is increased risk of cardiovascular disease in patients with rheumatoid arthritis. Primary cardiovascular disease prevention in rheumatoid arthritis patients is difficult, especially in those with high disease activity. According to current evidence, people with rheumatoid arthritis can significantly improve clinical indices and patient-reported outcomes by engaging in organized physical activity such as resistance training and aerobic activities. Additionally, participating in an exercise regimen can lower the risk of experiencing cardiovascular problems...
October 31, 2023: Rheumatology International
https://read.qxmd.com/read/37906254/sars-cov-2-seroprevalence-in-patients-with-autoimmune-rheumatic-diseases-versus-family-controls-a-multi-city-cross-sectional-survey
#12
JOURNAL ARTICLE
Ramnath Misra, Debdutta Bhattacharya, Sakir Ahmed, Sanjiv Amin, Vineeta Shobha, Alakendu Ghosh, Sapan C Pandya, Debaprasad Parai, Prasanta Padhan, Subhadra Priyadarshini, Ipsa Mohapatra, A Raj Kumar Patro, Ambika Prasad Mohanty, Sanghamitra Pati
There is uncertainty regarding the effect of the SARS-CoV-2 infection on patients with autoimmune rheumatic diseases (AIRD) who are on immunosuppressive drugs. We did a multicity cross-sectional seroprevalence study conducted in five different cities in India before COVID-19 immunization. Patients with a diagnosis of AIRD and DMARDs were included. Relatives of the patients, preferably staying in the same household with no known rheumatic diseases served as controls. Serum IgG antibodies to SARS-CoV-2 Receptor Binding Domain (RBD) of the spike protein and nucleoprotein (NP) were assayed in eight hundred and eighty nine sera (subjects with disease = 379 and in subjects without disease = 510)...
October 31, 2023: Rheumatology International
https://read.qxmd.com/read/37903914/franz-liszt-s-hand-osteoarthritis
#13
LETTER
Ilke Coskun Benlidayi
No abstract text is available yet for this article.
October 31, 2023: Rheumatology International
https://read.qxmd.com/read/37897662/covid-19-vaccination-and-infection-status-a-cross-sectional-survey-of-patients-with-rheumatic-diseases-in-china
#14
JOURNAL ARTICLE
Chen Chen, Saisai Huang, Linyu Geng, Peng Lai, Huan Dou, Huayong Zhang, Haifeng Chen, Jun Liang, Lingyun Sun
To evaluate the vaccination status and clinical practice of patients with rheumatic diseases (RD) during the COVID-19 pandemic in China and to explore the impact of vaccination on infection severity in patients with RD. A cross-sectional survey was conducted among RD patients in outpatient and inpatient settings of the Rheumatology and Immunology Department in our hospital. Participants' characteristics, vaccination status, COVID-19 infection status, and medication for acute COVID-19 were collected. A total of 749 valid surveys were included in the study...
October 28, 2023: Rheumatology International
https://read.qxmd.com/read/37891327/advancing-ai-in-rheumatology-critical-reflections-and-proposals-for-future-research-using-large-language-models
#15
LETTER
Partha Pratim Ray
No abstract text is available yet for this article.
October 27, 2023: Rheumatology International
https://read.qxmd.com/read/37889264/sapho-syndrome-current-clinical-diagnostic-and-treatment-approaches
#16
REVIEW
Tuba Demirci Yildirim, İsmail Sari
This review provides an overview of SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis), a rare autoinflammatory disease that primarily affects bones, skin, and joints. We conducted a search on Medline/PubMed using keywords such as SAPHO syndrome, chronic recurrent multifocal osteitis/osteomyelitis, and related terms. SAPHO syndrome is rare, with a reported frequency of 1 in 10,000 in the Caucasian population. However, the actual incidence of SAPHO syndrome is unknown, and the incidence of the disease is likely higher...
October 27, 2023: Rheumatology International
https://read.qxmd.com/read/37861727/endorsement-of-reporting-guidelines-and-clinical-trial-registration-across-scopus-indexed-rheumatology-journals-a-cross-sectional-analysis
#17
JOURNAL ARTICLE
Trevon Jelinek, Alexandra Shumard, Jay Modi, Caleb Smith, Danya Nees, Griffin Hughes, Matt Vassar
The purpose of this study was to investigate the instructions for authors of rheumatology journals and analyze their endorsement of reporting guidelines and clinical trial registration. Sixty rheumatology journals were selected by a research librarian and an investigator through the 2021 Scopus CiteScore tool. The instructions for authors' subsection of each journal was assessed to determine endorsement of study design-specific reporting guidelines or clinical trial registration. Descriptive statistics were calculated using R (version 4...
October 20, 2023: Rheumatology International
https://read.qxmd.com/read/37851077/pneumocystosis-in-a-patient-with-rheumatoid-arthritis-on-adalimumab-therapy-a-case-based-review
#18
REVIEW
Dimitris C Kounatidis, Vasileios Papadimitropoulos, Konstantinos Avramidis, Evgenia Plenga, Ioanna Tsiara, Elena Avgoustou, Natalia Vallianou, Dimitrios Vassilopoulos
Pneumocystis jirovecii pneumonia (PJP) is a potentially fatal type of pneumonitis, which may have devastating consequences. Typically, it occurs in immunocompromised patients, with the natural history varying depending on the presence or not of HIV infection. Staining and polymerase chain reaction (PCR) testing in induced sputum or bronchoalveolar lavage (BAL) is the cornerstone of the diagnosis, while trimethoprim-sulfamethoxazole is the treatment of choice. The etiological association of biologic agents with the occurrence of PJP is not entirely clear...
October 18, 2023: Rheumatology International
https://read.qxmd.com/read/37851076/miliarial-type-gout-in-association-with-chronic-use-of-glucocorticoids
#19
REVIEW
A Enríquez-Luna, C Soto-Fajardo, F Carranza-Enríquez, D Clavijo-Cornejo, A Lopez-Reyes, C Pineda
A 59-year-old male patient with long-standing tophaceous gout (more than 30 years) characterized by polyarticular involvement and recurrent disseminated tophi formation; his past medical history is relevant for poor adherence to urate-lowering medications, as well as persistent use of self-prescribed systemic glucocorticoids. Despite achieving therapeutic goals for serum uric acid levels, new tophi formation with an intradermal location in the form of "miliarial-type gout" was documented. Due to functional limitations, the patient underwent surgical resection of the olecranon bursa...
October 18, 2023: Rheumatology International
https://read.qxmd.com/read/37848675/vitamin-b12-cobalamin-supplementation-for-the-management-of-autoimmune-rheumatic-diseases-potential-indications-and-opportunity-for-future-research
#20
LETTER
Jozélio Freire de Carvalho, Steven John Coles, Allain Amador Bueno
No abstract text is available yet for this article.
October 17, 2023: Rheumatology International
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