Jagdish Mishra, Subhajit Chakraborty, Niharika, Ankan Roy, Soumen Manna, Tirthankar Baral, Piyasa Nandi, Samir K Patra
Mechanical forces may be generated within a cell due to tissue stiffness, cytoskeletal reorganization, and the changes (even subtle) in the cell's physical surroundings. These changes of forces impose a mechanical tension within the intracellular protein network (both cytosolic and nuclear). Mechanical tension could be released by a series of protein-protein interactions often facilitated by membrane lipids, lectins and sugar molecules and thus generate a type of signal to drive cellular processes, including cell differentiation, polarity, growth, adhesion, movement, and survival...
February 12, 2024: Journal of Cellular Biochemistry