journal
Journals Graefe's Archive for Clinical ...

Graefe's Archive for Clinical and Experimental Ophthalmology

https://read.qxmd.com/read/38300334/topographic-analysis-of-local-oct-biomarkers-which-predict-progression-to-atrophy-in-age-related-macular-degeneration
#21
JOURNAL ARTICLE
Navid Manafi, Alireza Mahmoudi, Mehdi Emamverdi, Giulia Corradetti, Stephanie Trejo Corona, Charles C Wykoff, SriniVas R Sadda
PURPOSE: To define optical coherence tomography (OCT) biomarkers that precede the development of complete retinal pigment epithelium and outer retinal atrophy (cRORA) at that location in eyes with age-related macular degeneration (AMD). METHODS: In this retrospective case-control study, patients with dry AMD who had evidence of cRORA and OCT data available for 4 years (48 ± 4 months) prior to the first visit with evidence of cRORA were included...
February 1, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38294513/intravitreal-anti-vascular-endothelial-growth-factor-and-combined-photodynamic-therapy-for-pachychoroid-neovasculopathy-long-term-treatment-outcomes
#22
JOURNAL ARTICLE
Nobuya Tanaka, Keiko Azuma, Shuichiro Aoki, Kohdai Kitamoto, Kohei Ueda, Ryosuke Fujino, Tatsuya Inoue, Ryo Obata
PURPOSE: To examine the long-term visual outcomes after initial treatment with combined photodynamic therapy (PDT) or aflibercept treat-and-extend (TAE) monotherapy in patients with pachychoroid neovasculopathy (PNV). METHODS: Patients diagnosed with PNV, initially treated with PDT combined with anti-vascular endothelial growth factor (VEGF) or intravitreal aflibercept (IVA) monotherapy in the TAE protocol and followed up for at least 6 months, were included in the study...
January 31, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38294512/three-dimensional-soft-tissue-reconstruction-and-volume-measurement-used-for-the-diagnosis-of-dysthyroid-optic-neuropathy
#23
JOURNAL ARTICLE
Lan Ma, Minghui Wang, Zheng Zhang, Xue Jiang, Zhijia Hou, Dongmei Li
PURPOSE: Dysthyroid optic neuropathy (DON) leads to vision loss. This study aimed to investigate a new method that can directly evaluate the change in muscle cone inner volume (MCIV) and distinguish DON orbits from non-DONs. MATERIALS AND METHODS: This study included 54 patients (108 orbits) who were diagnosed with thyroid eye disease and treated at the Beijing Tongren Hospital between December 2019 and September 2021. The extraocular muscle volume (EOMV), orbital fat volume (OFV), and bony orbit volume (BOV) of the patients were measured using three-dimensional reconstruction...
January 31, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38289371/type-1-and-type-2-torpedo-maculopathy
#24
JOURNAL ARTICLE
Annekatrin Rickmann, Jan-Philipp Bodenbender, Faik Gelisken, Laura Kühlewein
PURPOSE: To analyze torpedo maculopathy (TM) and to report the characteristics of the disease. METHODS: Retrospective study. The review of a database for clinical diagnosis identified eight patients with TM lesions in the retina between 2016 and 2022. Multimodal imaging was used to analyze the cases. RESULTS: All cases were unilateral, asymptomatic, and hypopigmented. They were associated by surrounding hyperpigmented retinal pigment epithelium changes to varying degrees...
January 30, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38285248/biomechanical-properties-measured-with-dynamic-scheimpflug-analyzer-in-central-serous-chorioretinopathy
#25
JOURNAL ARTICLE
Shuichiro Aoki, Ryo Asaoka, Keiko Azuma, Kohdai Kitamoto, Kohei Ueda, Tatsuya Inoue, Ryo Obata
PURPOSE: Recent evidence suggests that venous congestion at the vortex vein significantly contributes to the development of central serous chorioretinopathy (CSCR), and sclera is observed to be thicker in affected eyes. This study aims to investigate whether eyes with CSCR exhibit stiff corneas, measured using Corneal Visualization Scheimflug Technology (Corvis ST), which may serve as an indicator of scleral stiffness. METHODS: This retrospective case-control study comprises 52 eyes from 33 patients diagnosed with CSCR and 52 eyes from 32 normal controls without CSCR...
January 29, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38280029/subthreshold-laser-treatment-in-retinal-diseases-a-mini-review
#26
REVIEW
Andrzej Grzybowski, Zuzana Sulaviková, Maciej Gawęcki, Igor Kozak
PURPOSE: To summarize the mechanism and the clinical applications of subthreshold laser (STL) in retinal practice. Subthreshold or "non-destructive" laser includes all types of laser treatments that produce minimal or no damage to the tissues and no visible signs after application. METHODS: A descriptive review of articles from literature databases (PubMed, Medline, Embase, Cochrane, Web of Science) published before August 2023, which discuss current STL treatments of retinal diseases...
January 27, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38270630/platelet-concentrates-in-macular-hole-surgery-a-journey-through-the-labyrinth-of-terminology-preparation-and-application-a-comprehensive-review
#27
REVIEW
Francesco Gelormini, Sergio D'antico, Federico Ricardi, Guglielmo Parisi, Enrico Borrelli, Paola Marolo, Fabio Conte, Marika Salafia, Michele Reibaldi
The surgical management of macular holes is undergoing continuous evolution, with recent focus on the utilization of platelet concentrates as a promising adjunctive intervention. Currently, they present a valid surgical approach for achieving anatomical and functional success with a non-inferiority comparably to the alternative surgical techniques. Nonetheless, the utilization of varied platelet concentrates terminologies, coupled with the lack of standardization in their preparation methodologies, engenders both lexical confusion and challenges in comparing scientific studies published up until now...
January 25, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38270629/repeatability-and-reproducibility-of-quantitative-oct-angiography-measurements-from-table-top-and-portable-flex-spectralis-devices
#28
JOURNAL ARTICLE
Arathi Ponugoti, Hoan Ngo, Sandra Stinnett, Michael P Kelly, Lejla Vajzovic
PURPOSE: The recent development of a portable investigational handheld OCT-angiography (OCTA) device has allowed for expansion of imaging into the operating room (OR) in addition to standard in-clinic imaging. The aim of this study was to assess intravisit repeatability and intervisit reproducibility of retinal microvasculature measures and central retinal thickness for in-clinic table-top and portable OR compatible OCTA devices. METHODS: Repeated 10 × 10 OCTA images were acquired in 20 healthy adult participants on two separate visit days using Spectralis spectral-domain OCTA table-top and investigational armature suspended Flex systems...
January 25, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38244084/optical-coherence-tomography-angiography-macular-biomarkers-of-peripheral-retinal-ischemia-in-diabetic-macular-edema-secondary-endpoints-from-the-clinical-study-fovea
#29
JOURNAL ARTICLE
Rita Serra, Florence Coscas, Jean François Boulet, Diogo Cabral, Thi Ha Chau Tran, Antonio Pinna, Marco Lupidi, Gabriel Coscas
PURPOSE: To investigate the relationship between the macular values of fractal dimension (FD) and lacunarity (LAC) on optical coherence tomography angiography (OCTA) images and the presence of peripheral retina non-perfusion areas (NPAs) on fluorescein angiography (FA) in patients with treatment-naïve diabetic macular edema (DME). METHODS: Fifty patients with treatment-naïve DME underwent a full ophthalmic examination, including best-corrected visual acuity measurement, FA, spectral-domain optical coherence tomography, and OCTA...
January 20, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38240778/a-comparison-of-antimicrobial-regimen-outcomes-and-antibiogram-development-in-microbial-keratitis-a-prospective-cohort-study-in-alexandria-egypt
#30
JOURNAL ARTICLE
Amira A Nayel, Noha A Hamdy, Tamer H Massoud, Nelly M Mohamed
INTRODUCTION: Antimicrobial resistance in microbial keratitis has not been previously explored in Alexandria. We aim to recommend effective therapies through identification of etiological agents, determination of antimicrobial susceptibilities, and comparing outcomes of empiric topical antimicrobials. METHODS: In this 2022 prospective cohort conducted in Alexandria Main University Hospital cornea clinic, antimicrobial susceptibilities of isolated microorganisms from corneal scrapings were detected and antibiograms were developed...
January 19, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38240777/accuracy-of-bruch-s-membrane-opening-minimum-rim-width-and-retinal-nerve-fiber-layer-thickness-in-glaucoma-diagnosis-depending-on-optic-disc-size
#31
JOURNAL ARTICLE
Verena Anna Englmaier, Jens Julian Storp, Martin Dominik Leclaire, Larissa Lahme, Viktoria Constanze Brücher, Julia Biermann, Raphael Diener, Nicole Eter
BACKGROUND/AIM: The aim of this paper is to compare retinal nerve fiber layer thickness (RNFL) and Bruch's membrane opening-based minimum rim width (BMO-MRW) in terms of their performance in detecting early and moderate/advanced glaucoma using receiver operating characteristics (ROC) analysis and the classification using the 5th percentile as a cut-off. METHODS: One hundred eyes from 100 patients with early glaucoma (mean deviation (MD): < -5.0 dB) and 100 eyes from 100 patients with moderate/advanced glaucoma (MD: > -5...
January 19, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38231247/differences-between-young-and-elderly-polypoidal-choroidal-vasculopathy-patients-with-and-without-pachychoroid-phenotypes
#32
JOURNAL ARTICLE
Yuelin Wang, Wenfei Zhang, Jingyuan Yang, Xinyu Zhao, Lihui Meng, Youxin Chen, Xiao Zhang
PURPOSE: To investigate the distinct characteristics between young and elderly polypoidal choroidal vasculopathy (PCV) patients based on the pachy- or non-pachychoroid phenotypes. METHODS: PCV patients treated with intravitreal injections of Conbercept based on the 3 + PRN regimen from 27 centers of China PCV Research Alliance were included. Patients were categorized into the young and the elderly aged group based on the cut-off point determined using the Youden method according to the pachychoroid phenotypes...
January 17, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38231246/170%C3%A2-years-of-data-mining-history-and-future
#33
EDITORIAL
Bernd Kirchhof
No abstract text is available yet for this article.
January 17, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38231245/graefe-s-archive-for-clinical-and-experimental-surgery-170th-anniversary
#34
EDITORIAL
Antonia M Joussen
No abstract text is available yet for this article.
January 17, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38224344/comparative-efficacy-of-brolucizumab-half-dose-photodynamic-therapy-and-aflibercept-in-managing-chronic-central-serous-chorioretinopathy
#35
JOURNAL ARTICLE
Yu-Te Huang, Peng-Tai Tien, Po-Yu Chen, Chi-Lan Yang, San-Ni Chen
PURPOSE: To compare the efficacy of brolucizumab, half-dose PDT, and aflibercept in treating chronic central serous chorioretinopathy (CSC). METHODS: A retrospective cohort study with chronic CSC patients who underwent intravitreal injection of one shot of brolucizumab or aflibercept in the first 3 months, followed by pro re nata regimens or a single session of half-dose PDT, was retrospectively reviewed. The primary outcome measure was the proportion of eyes that achieved complete absorption of retinal fluid without requiring any rescue treatment...
January 15, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38217768/predescemetic-femtosecond-laser-assisted-deep-anterior-lamellar-keratoplasty-with-simulated-pachymetry
#36
JOURNAL ARTICLE
David Diaz-Valle, Barbara Burgos-Blasco, Mayte Ariño-Gutierrez, Jose Antonio Gegundez-Fernandez
No abstract text is available yet for this article.
January 13, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38217767/flare-levels-after-intravitreal-injection-of-brolucizumab-for-diabetic-macular-edema
#37
JOURNAL ARTICLE
Yushi Ichihashi, Yoshihiro Takamura, Takao Hirano, Masahiko Shimura, Keisuke Yoneda, Keiichiro Konno, Yutaka Yamada, Masakazu Morioka, Makoto Gozawa, Takehiro Matsumura, Masaru Inatani
PURPOSE: This study aimed to evaluate anterior flare intensity (AFI) after intravitreal injection of brolucizumab (IVBr) in patients with diabetic macular edema (DME), and to identify the factors associated with the change of AFI after IVBr. METHODS: This prospective multicenter study was conducted at five sites in Japan for patients with DME who underwent a single IVBr. AFI and central retinal thickness (CRT) were measured using a laser flare meter and spectral-domain optical coherence tomography, respectively, at weeks 0 and 6...
January 13, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38217766/accuracy-of-intraocular-lens-power-formulas-in-eyes-with-keratoconus-multi-center-study-in-japan
#38
JOURNAL ARTICLE
Tomohiro Yokogawa, Yosai Mori, Hidemasa Torii, So Goto, Yumi Hasegawa, Takashi Kojima, Kazutaka Kamiya, Takuya Shiba, Kazunori Miyata
PURPOSE: To assess the accuracy of intraocular lens (IOL) power formulas, namely, SRK/T, Haigis, Barrett Universal II, Barrett True-K for keratoconus, Kane formula, and Kane formula for keratoconus, for cataract with keratoconus in Japanese eyes. SETTING: Five surgical sites in Japan. DESIGN: A retrospective case series. METHODS: Eyes with keratoconus undergoing cataract surgery were included. Postoperative refraction was compared with the prediction by the formulas...
January 13, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38214734/measurement-of-the-retinal-venous-pressure-with-a-new-instrument-in-patients-with-primary-open-angle-glaucoma
#39
JOURNAL ARTICLE
Richard Stodtmeister, Aline Menzel, Anna Klimova, Robert Herber, Karin R Pillunat, Lutz E Pillunat
PURPOSE: To compare the results of retinal venous pressure (RVP) measurement performed with contact lens dynamometry (CLD) and with the new IOPstim. METHODS: In this cross-sectional study, we included 36 patients with primary open angle glaucoma with a median age (Q25; Q75) of 74 (64; 77) years (m/f = 18/18), baseline intraocular pressure (IOP): 13.9 (12.2; 15.1) mmHg. Median mean defect: - 5.8 (- 11.9; - 2.6) db...
January 12, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38206414/macular-dystrophy-in-kabuki-syndrome-due-to-de-novo-kmt2d-variants-refining-the-phenotype-with-multimodal-imaging-and-follow-up-over-10-years-insight-into-pathophysiology
#40
JOURNAL ARTICLE
Veronika Vaclavik, Aurelie Navarro, Alain Jacot-Guillarmod, Armand Bottani, Young Joo Sun, Joel A Franco, Vinit B Mahajan, Vasily Smirnov, Isabelle Bouvet-Drumare
BACKGROUND: Kabuki Syndrome is a rare and genetically heterogenous condition with both ophthalmic and systemic complications and typical facial features. We detail the macular phenotype in two unrelated patients with Kabuki syndrome due to de novo nonsense variants in KMT2D, one novel. A follow-up of 10 years is reported. Pathogenicity of both de novo nonsense variants is analyzed. METHODS: Four eyes of two young patients were studied by full clinical examination, kinetic perimetry, short wavelength autofluorescence, full field (ff) ERGs, and spectral-domain optical coherence tomography (SD-OCT)...
January 11, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
journal
journal
28313
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.