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Journals Graefe's Archive for Clinical ...

Graefe's Archive for Clinical and Experimental Ophthalmology

https://read.qxmd.com/read/36949170/pediatric-herpes-zoster-ophthalmicus-a-systematic-review
#1
REVIEW
Farida E Hakim, Kamran Riaz, Asim Farooq
PURPOSE: While typically affecting older adults and immunocompromised individuals, herpes zoster ophthalmicus (HZO) has been reported with varying manifestations and complications in children. In this review, we evaluate reported cases of pediatric HZO in the literature and discuss the epidemiology, risk factors, clinical presentation, treatment and outcomes. METHODS: A literature search on PubMed, Scopus, and Web of Science databases was performed using the terms "pediatric herpes zoster ophthalmicus" and "herpes zoster ophthalmicus children...
March 23, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36944752/network-meta-analysis-comparing-efficacy-and-safety-of-different-protocols-of-corneal-cross-linking-for-the-treatment-of-progressive-keratoconus
#2
REVIEW
Lan Ding, Ling Sun, Xingtao Zhou
PURPOSE: This study aimed to determine the preferred protocol of corneal collagen cross-linking (CXL) in the treatment of progressive keratoconus. METHODS: Relevant studies were retrieved in PubMed, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL). Maximum keratometry value (Kmax ), best spectacle-corrected visual acuity (BSCVA), manifest refraction spherical equivalent (MRSE), and endothelial cell density (ECD) were evaluated in network meta-analysis...
March 22, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36943459/the-paul%C3%A2-glaucoma-implant-1-year-results-of-a-novel-glaucoma-drainage-device-in-a-paediatric-cohort
#3
JOURNAL ARTICLE
Neeru Amrita Vallabh, Ravi Mohindra, Elizabeth Drysdale, Fiona Mason, Cecilia H Fenerty, Kenneth Yau
PURPOSE: The PAUL® glaucoma implant (PGI) is a novel glaucoma drainage device, which has not been previously reported in paediatric glaucoma management. This study aims to evaluate the safety and effectiveness of the PGI in a paediatric cohort. METHODS: A retrospective evaluation of 25 cases of paediatric PGI surgery (age 8 months to 16 years) was performed at Manchester Royal Eye Hospital between September 2019 and July 2020. Primary outcome measures included failure (intraocular pressure (IOP) > 21 mmHg or < 20% reduction of IOP, removal of the implant, further glaucoma intervention or visual loss...
March 21, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36933010/clinical-features-and-factors-affecting-prognosis-and-partial-deterioration-of-ocular-papilloma-a-retrospective-study-of-298-cases
#4
JOURNAL ARTICLE
Huan Jian, Weimin He
PURPOSE: This study aimed to analyze the clinicopathological features of ocular papilloma, a common benign tumor, and the risk factors related to its recurrence and partial deterioration. METHODS: We collected and analyzed the clinical information of 298 patients (51.68% males) with mean age of 41.54 ± 21.95 years, in the ophthalmology department of the West China Hospital. Clinical and pathological factors that might be related to papilloma recurrence and partial deterioration were studied...
March 18, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36933009/multipurpose-ultrasonographic-characteristics-of-primary-uveal-malt-lymphoma
#5
JOURNAL ARTICLE
Lili Zhang, Ting Zhang, Gezhi Xu, Chaoran Zhang, Jiang Qian, Qing Chang, Yingwen Bi, Qian Chen
PURPOSE: To investigate the ultrasonographic features in patients with primary uveal mucosa-associated lymphoid tissue (MALT) lymphoma. METHODS: Medical records of 12 patients (13 eyes) diagnosed with primary uveal MALT lymphoma between September 2014 and September 2021 were retrospectively reviewed. Ultrasonography, B-scan ultrasonography, color Doppler flow imaging, and ultrasound biomicroscopy findings were retrieved from the medical records. RESULTS: Mean age of the included patients was 59...
March 18, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36930322/association-between-myopia-and-complications-of-glaucoma-with-retinal-diseases-investigation-of-a-large-medical-insurance-database
#6
LETTER
Takahiro Ninomiya, Hiroshi Kunikata, Makoto Ishikawa, Toru Nakazawa
No abstract text is available yet for this article.
March 17, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36929056/benefit-of-intravitreal-injections-in-patients-with-sub-threshold-baseline-visual-acuity-a-retrospective-single-centre-study
#7
JOURNAL ARTICLE
Nina-Antonia Grimm, Sarah Fahimi, Fabian Kück, Patricia Take, Peer Lauermann, Anna Nguyen-Hoehl, Hans Hoerauf, Nicolas Feltgen, Sebastian Bemme
PURPOSE: To investigate the lower visual acuity threshold for recommending intravitreal injection therapy (IVI). The lower limit of 1.3 logMAR best-corrected visual acuity (BCVA) was adopted in 2006 and has been maintained since then. METHODS: In this retrospective study, data from patients with a logMAR BCVA ≤ 1.3 and 24 months follow-up were analysed. We included patients with neovascular age-related macular degeneration (nAMD), diabetic macular oedema (DME), or retinal vein occlusion (RVO)...
March 16, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36929055/the-impact-of-case-complexity-in-resident-performed-cataract-surgery
#8
JOURNAL ARTICLE
Sally Se Park, Michael Tseng, Zara Mian, Jee-Young Moon, Anurag Shrivastava
PURPOSE: To evaluate the association of capsular dye and/or a pupil expansion device (PED) usage on the rate of major complication in resident-performed cataract extraction. METHODS: Resident cataract surgeries between 2016 and 2019 were included. The primary outcomes were anterior or posterior vitrectomy (AVx and PPVx). Cases were grouped by the use of a PED and/or capsular staining along with additional preoperative risk factors. RESULTS: Of the 1,348 cases, 371 (27...
March 16, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36917317/impact-of-major-age-related-eye-disorders-on-health-related-quality-of-life-assessed-by-eq-5d-a-systematic-review-and-meta-analysis
#9
REVIEW
Jia-Yan Kai, Yue Xu, Dan-Lin Li, Miao Zhou, Pei Wang, Chen-Wei Pan
PURPOSE: This study is to quantitatively estimate the health-related quality of life (HRQOL) impact of major age-related eye diseases (AREDs) including cataract, glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR) assessed by the EuroQoL Five-Dimensional Questionnaire (EQ-5D). METHODS: PubMed, Embase, Cochrane Library, and CINAHL were searched until October 20, 2022. Studies were included if they reported the EQ-5D health utility score (HUS) or visual analogue scale (VAS) score of both AREDs patients and healthy controls...
March 14, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36917316/effect-of-statins-on-the-age-of-onset-of-age-related-macular-degeneration
#10
JOURNAL ARTICLE
Durga Ganesh, Jeffrey N Chiang, Giulia Corradetti, Noah Zaitlen, Eran Halperin, Srinivas R Sadda
BACKGROUND: This study evaluated the relationship between statin use and the age of onset of age-related macular degeneration (AMD). METHODS: Electronic Health Records from 52,840 patients evaluated at University of California Los Angeles (UCLA) Ophthalmology Clinics and 9,977 patients evaluated at University of California San Francisco (UCSF) Ophthalmology Clinics were screened. Survival analysis was performed using Cox proportional hazards regression models and visualized using Kaplan Meier survival curves, with the following covariates-sex, ethnicity, smoking history, fluoxetine use, obesity, diabetes mellitus, and hypertension...
March 14, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36914818/analysis-of-vault-prediction-in-phakic-implantable-phakic-collamer-lenses-manufacturer-s-calculator-vs-theoretical-formulae-vs-clinical-practice
#11
JOURNAL ARTICLE
Jesús Beltrán-Murcia, Laureano Álvarez-Rementería Capelo, Vanesa Blázquez-Sánchez
BACKGROUND: Implantable collamer phakic (ICL) intraocular lens sizing calculations are necessary to avoid complications associated to inadequate sizing. Historically, Holladay R, Dougherty, Hernández-Matamoros, and other authors have tried to create new formulas that solve calculation problems and provide higher reliability. In addition, in recent years, the appearance of new equipment, parameters, and formulas have led to significant progress. This paper compares the sizing according to manufacturer's method and other methods...
March 14, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36884063/influence-of-a-multifocal-intraocular-lens-centration-and-eye-angles-on-light-distortion-and-ocular-scatter-index
#12
JOURNAL ARTICLE
Joaquín Fernández, Noemí Burguera, Carlos Rocha-de-Lossada, Rahul Rachwani-Anil, Manuel Rodríguez-Vallejo
PURPOSE: To assess how eye axes and multifocal intraocular lens (MIOL) centration may impact the light distortion index (LDI) and ocular scatter index (OSI). METHODS: Fifty-eight subjects implanted with the trifocal MIOL Q-Flex M 640PM or Liberty 677MY (Medicontur) were included in this retrospective analysis. The following variables were collected with the Pentacam Wave (Oculus) considering the vertex normal as the coordinates center: chord-mu to the center of the pupil, chord-alpha to the geometrical center of the cornea, and chord-MIOL to the center of the diffractive ring...
March 8, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36884062/application-of-optical-coherence-tomography-angiography-for-microvascular-changes-in-patients-treated-with-hydroxychloroquine-a-systematic-review-and-meta-analysis
#13
JOURNAL ARTICLE
André Ferreira, Rita Anjos, Rafael José-Vieira, Miguel Afonso, Ana Carolina Abreu, Sílvia Monteiro, Mafalda Macedo, José P Andrade, Maria João Furtado, Miguel Lume
BACKGROUND: Retinal toxicity with long-term hydroxychloroquine (HCQ) treatment is a major concern. This systematic review aims to assess the application of optical coherence tomography angiography (OCTA) to detect microvascular alterations in patients under HCQ. METHODS: PubMed, Scopus, Web of Science, and Cochrane Library databases were systematically searched until January 14, 2023. Studies using OCTA as a primary diagnostic method to evaluate the macular microvasculature of HCQ users were included...
March 8, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36882562/oral-minocycline-for-the-treatment-of-retinitis-pigmentosa-associated-cystoid-macular-edema-results-of-a-phase-i-ii-clinical-trial
#14
JOURNAL ARTICLE
Amisha D Dave, Katherine G Chen, Trent Tsun-Kang Chiang, Janani Singaravelu, Jason A Alvarez, Wai T Wong, Catherine A Cukras
PURPOSE: The etiology of retinitis pigmentosa (RP)-associated cystoid macular edema (CME) has been related to retinal neuroinflammation and microglial activation. Minocycline, a drug FDA-approved for anti-microbial indications, also inhibits microglial activation and expression of inflammatory mediators. This study investigates the safety and efficacy of oral minocycline as primary treatment for RP-associated CME. METHODS: A single-center, prospective, open-label phase I/II clinical trial enrolled five participants with RP-associated CME...
March 8, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36882561/predictive-factors-for-outcomes-of-half-dose-photodynamic-therapy-combined-with-aflibercept-for-pachychoroid-neovasculopathy
#15
JOURNAL ARTICLE
Jun Takeuchi, Hikaru Ota, Yuyako Nakano, Etsuyo Horiguchi, Yosuke Taki, Yasuki Ito, Hiroko Terasaki, Koji M Nishiguchi, Keiko Kataoka
PURPOSE: To assess the effects of half-dose photodynamic therapy (PDT) combined with an intravitreous aflibercept (IVA) injection for pachychoroid neovasculopathy (PNV) and its predictive factors. METHODS: Clinical information of 43 patients (43 eyes) with PNV obtained before and 6 months after treatment with half-dose PDT combined with IVA was retrospectively analyzed. Patients were categorized into the sufficient (25 eyes, 58.1%) or insufficient (18 eyes, 41...
March 8, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36881261/more-on-light-dysphotopsia-origin-in-pseudophakia
#16
EDITORIAL
Andrzej Grzybowski, Jan-Willem Beenakker
No abstract text is available yet for this article.
March 7, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36881260/use-of-corneal-cross-linking-beyond-keratoconus-a-systemic-literature-review
#17
REVIEW
Richard P C Manns, Asaf Achiron, Boris Knyazer, Omar Elhaddad, Kieran Darcy, Tal Yahalomi, Derek Tole, Venkata S Avadhanam
PURPOSE: The success of corneal collagen cross-linking in altering keratoconus' clinical course has driven a search for further uses of this procedure. This literature review aims to analyze the scientific evidence available for the benefit of cross-linking in the management of ophthalmic diseases other than progressive keratoconus or ectasia induced by corneal refractive procedures. METHODS: A systemic literature review. RESULTS: We reviewed 97 studies...
March 7, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36877299/sequential-structural-and-functional-change-in-geographic-atrophy-on-multimodal-imaging-in-non-exudative-age-related-macular-degeneration
#18
JOURNAL ARTICLE
Jeong Hyun Lee, Jeeyun Ahn, Joo Young Shin
PURPOSE: To investigate the temporal order of photoreceptor atrophy, retinal pigment epithelium (RPE) atrophy and visual acuity loss in patients with center-involving geographic atrophy (GA) in non-exudative age-related macular degeneration (neAMD). METHODS: Forty eyes of 25 consecutive patients who eventually developed center-involving GA were investigated. Fundus autofluorescence (FAF) and infrared image coupled optical coherence tomography (OCT) were acquired at each visit...
March 6, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36869890/persistence-of-vascular-empty-sleeves-in-choroidal-neovascularization-after-vegf-therapy-in-both-animal-models-and-humans
#19
JOURNAL ARTICLE
Iori Wada, Shintaro Nakao, Yosuke Fukuda, Satomi Shiose, Atsunobu Takeda, Ram Kannan, Koh-Hei Sonoda
PURPOSE: Choroidal neovascularization (CNV) often recurs during anti-vascular endothelial growth factor (VEGF) therapy; however, little is known about the mechanism of vascular regrowth. Vascular regrowth along the empty sleeves of basement membranes was proposed as a mechanism for recurrence after the reversal of VEGF inhibition in tumors. This study investigated whether the proposed mechanism is involved in CNV during VEGF therapy. METHODS: We made two observations using a mice model, as well as patients with CNV...
March 4, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/36869889/the-outcomes-of-a-low-cost-non-valved-glaucoma-drainage-device-using-mitomycin-c-1-year-results
#20
JOURNAL ARTICLE
Mo'mena Ahmad A Awad-Allah, Amr Saleh Mousa, Doaa Maamoun Ashour
PURPOSE: To evaluate the indications, outcomes, and complications of the usage of Aurolab Aqueous Drainage Implant (AADI) using mitomycin-C. METHODS: A retrospective case series of patients who underwent AADI placement using mitomycin-C between April 2018 and June 2020 at Ain Shams University Hospitals, Cairo, Egypt. The data was extracted from the records of the patients with a minimum of 1 year of follow-up. Complete success was defined as IOP ≥ 5 mmHg and ≤ 21 mmHg or reduction of IOP by ≥ 20% from baseline without antiglaucoma medications (AGMs)...
March 4, 2023: Graefe's Archive for Clinical and Experimental Ophthalmology
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