Ashutosh Bhave
In the past few years, psilocybin, a psychedelic compound found in "magic mushrooms" (psilocybin mushrooms), has undergone decriminalization in numerous cities across the US and has been legalized in Oregon and Colorado. Proponents of psilocybin decriminalization have emphasized its therapeutic potential in treating mental health disorders. Furthermore, psilocybin mushrooms are considered the safest psychedelic option, with lower potency and a reduced risk of overdoses and emergency hospitalizations compared to other prevalent psychedelics, such as LSD (lysergic acid diethylamide) and MDMA (3,4-methylenedioxymethamphetamine)...
July 10, 2024: Journal of Psychoactive Drugs
B Romeo, E Kervadec, B Fauvel, L Strika-Bruneau, A Amirouche, V Verroust, P Piolino, A Benyamina
Treating cannabis use disorder remains a significant challenge in the field of addiction medicine. Some recent studies point to psychedelic-assisted psychotherapy as a potential treatment option for substance use disorders. The objective of this study was therefore to explore the impact of naturalistic psychedelic experiences on cannabis use and psychological flexibility. An online retrospective survey was carried out on 152 cannabis users who also reported a significant experience induced by psychedelics in the past...
July 3, 2024: Journal of Psychoactive Drugs
Luke Muschialli, Justin C Yang, Teyl Engstrom, Cheneal Puljevic, Edoardo Beltazar, Emmanuel Beltazar, Owais Siddique, Jason Ferris, Dean J Connolly
Sexualized drug use (SDU) describes drug-facilitated sexual enhancement, and chemsex is an SDU subculture involving the use of specific drugs by men who have sex with men (MSM). This study aimed to identify research trends, foci, and themes within the SDU and chemsex-specific literature. The Web of Science Core Collection was searched with a list of SDU synonyms. All SDU-related articles were analyzed using the R package, bibliometrix. Full text review identified chemsex-specific records, and text was extracted verbatim for content analysis in Leximancer...
July 3, 2024: Journal of Psychoactive Drugs
Lynda G Balneaves, David Hammond, Shelley Turner, Nathan Nickel, Roberta L Woodgate, Cody Z Watling
Canada legalized the use of non-medical cannabis in 2018. This study examines youth and young adults' knowledge and perceptions of harms, benefits, and education around cannabis use since legalization. An online survey was completed by a convenience sample of 1,759 individuals aged 12-25 years living in Manitoba, Canada. Most participants ( n  = 1,525, 86.7%) reported receiving education on the potential effects/harms related to cannabis; the most common topics included driving and cannabis use (79...
July 1, 2024: Journal of Psychoactive Drugs
Dima Audi, Shorouk Hajeer, Marie-Belle Saab, Lea Saab, Hayat Harati, Alban Desoutter, Elie Al Ahmar, Elias Estephan
Cannabis is one of the most commonly utilized recreational drugs. However, increasing evidence from the literature suggests harmful implications on cognition. Thus, the main aim of the current review is to summarize literature findings pertaining to the impact of cannabis on neurocognitive skills, focusing on the imaging biomarkers provided by MRI. Two reviewers navigated the literature independently using four main search engines including PubMed and Cochrane. Articles were first evaluated through their title and abstract, followed by full-text assessment...
June 29, 2024: Journal of Psychoactive Drugs
Tonći Mastelić, Tonka Borovina Marasović, Marija Franka Žuljević, Mirjana Sučević Ercegovac, Mariano Kaliterna, Neda Pleić, Dora Vukorepa, Joško Topić, Marija Žuljan Cvitanović, Davor Lasić, Boran Uglešić, Slavica Kozina, Trpimir Glavina
For some time now, there has been an increased interest in psychedelics among scientists and mental health experts. Given that experts introduce therapy and advise patients, it is important to know their views. Therefore, the aim of our research was to examine and compare the attitudes of psychiatrists and psychologists toward psychedelics. We were interested in how they are formed and what is the role of personality in that process. We included 218 respondents, of which 92 were psychiatrists and 126 were psychologists...
June 27, 2024: Journal of Psychoactive Drugs
Chelsea Spence, Mary E Kurz, Thomas C Sharkey, Bryan Lee Miller
Opioid misuse continues to cause significant harm. To investigate current research, we conducted a scoping literature review of disease spread models of opioid misuse from January 2000 to December 2022. In total, 85 studies were identified and examined for the opioids modeled, model type, data sources used and model calibration and validation. Most of the studies (58%, 49) only modeled heroin; the next largest categories were prescription opioids and unspecified opioids which accounted for 9% (8) each. Most models were theoretical compartmental models (57) or applied compartmental models (21)...
June 23, 2024: Journal of Psychoactive Drugs
Brian S Barnett, Curtis J Koons, Vincent Van den Eynde, Peter Kenneth Gillman, J Alexander Bodkin
Data on medication interactions with psychedelics are limited. Here we present what may be the first published report of a hypertensive emergency following the combination of psilocybin mushrooms with a monoamine oxidase inhibitor (MAOI). A 42-year-old man with treatment-resistant major depressive disorder took 1 g of Psilocybe cubensis mushrooms, while prescribed tranylcypromine, extended-release dextroamphetamine-amphetamine, and other medications. Approximately half an hour later, he developed severe hypertension with chest pain, palpitations, and headache...
June 21, 2024: Journal of Psychoactive Drugs
Baksun Sung
Cocaine-related mortality rates have risen sharply since 2013 and social vulnerability is a crucial indicator for drug-related mortality rates. Therefore, the purpose of this study was to investigate the relationship between social vulnerability and cocaine-related mortality rates in U.S. counties. The Data were collected from the CDC WONDER, CDC's Social Vulnerability Index (CDC's SVI), and American Community Survey (ACS). The Data were analyzed by spatial autoregression models. According to present results, first, counties with social vulnerability (socioeconomic) were positively related to higher rates of cocaine overdose death (spatial lag: B = 0...
June 11, 2024: Journal of Psychoactive Drugs
Gila Chen
Substance use is a multifaceted disorder of the whole person that is manifested on three levels: intrapersonal, interpersonal, and spiritual. Previous research has demonstrated that self-forgiveness and gratitude help build personal and social resources and reinforce the process of recovery from substance use disorders. The aims of the present narrative review article were to (a) explore self-forgiveness and gratitude as psychological mechanisms of behavioral change in recovery through the lens of positive criminology and recovery capital approach, (b) review the practice of self-forgiveness and gratitude in the Narcotics Anonymous (NA) and Alcoholics Anonymous (AA) programs, and (c) present a conceptual model of self-forgiveness and gratitude in long-term recovery...
June 11, 2024: Journal of Psychoactive Drugs
Sandeep M Nayak, Sydney H White, Samantha N Hilbert, Matthew X Lowe, Heather Jackson, Roland R Griffiths, Albert Garcia-Romeu, David B Yaden
Recent studies suggest psychedelic use may be associated with changes in a variety of beliefs or belief-like states, including increased 1) mind perception, 2) non-naturalistic beliefs, and 3) Atheist-Believer status (e.g. believer, agnostic, or nonbeliever). We conducted a prospective longitudinal study among participants ( N  = 657) who planned to have a psilocybin experience outside a laboratory setting. We asked participants about their beliefs concerning mind perception of various entities, specific metaphysical positions, and Atheist-Believer status both before (and after their experience...
May 7, 2024: Journal of Psychoactive Drugs
Jack E Henningfield, Sean J Belouin, David B Yaden, Julian Urrutia, Brian T Anderson, Ann Berger, Charles S Grob, Beatriz C Labate, Larissa J Maier, M Catherine Maternowska, Frank Weichold, Veronica Magar
No abstract text is available yet for this article.
May 6, 2024: Journal of Psychoactive Drugs
Dave Rojas, Diane C Zelman, Alexander O Hauson, Irina Alexander
Black, Indigenous, and People of Color (BIPOC), and other minoritized populations are insufficiently represented in research on therapeutic psychedelics. This research was a phenomenological qualitative exploration of a culturally diverse (Hispanic, African American, Asian, Native American, biracial, or LGBTQIA+) and low-income sample of 15 individuals receiving ketamine-assisted psychotherapy (KAP) at a sliding-scale fee community clinic. Participants were interviewed after a ketamine session, after a ketamine integration session, and one month later...
May 2, 2024: Journal of Psychoactive Drugs
Sean M Viña
Research has found that psychedelic use is associated with positive behavioral changes, however research has yet to explore the relationship between socio-cultural conditions on this relationship. This paper intends to fill this gap by testing the effects of religious participation and beliefs on the relationship between psychedelic use and behaviors. This study examines the relationship between Lifetime Classic Psychedelic Use (LCPU), different aspects of religion (such as salience and attendance), and the likelihood of committing a violent assault...
April 25, 2024: Journal of Psychoactive Drugs
J Konadu Fokuo, Paul J Hutman, Valerie A Gruber, Carmen L Masson, Paula J Lum, Dylan M Bush, Jessica A Naugle, James L Sorensen
Stigma is a public health concern. Stigmatizing attitudes toward persons with substance use disorders (SUDs) can adversely impact clinical care and outcomes. Beliefs about SUD, prior experience and familiarity to persons with SUD, and educational curricula drive attitudes among health-care workers. In 2019, nursing and nursing assistant students were recruited through an online survey platform. Participants completed an SUD knowledge test and a survey assessing education, beliefs, personal experience, and confidence in recognizing the signs and symptoms of SUD...
April 22, 2024: Journal of Psychoactive Drugs
Jamarie Geller, Nicolas Glynos, Andrew Lemmen, Rachel Pacilio, Daniel J Kruger, Avinash Hosanagar
This study aimed to characterize attitudes and identify gaps in trainee knowledge and education that may impact the field's readiness for the reemergence of psychedelic use in psychiatry. A two-part survey was sent out targeting medical and allied professional trainees who may interact with patients using or planning to use psychedelics therapeutically. Collected data for part one characterized demographics, sources of information, attitudes, experiences, and amount and type of education available about psychedelics in training programs...
April 16, 2024: Journal of Psychoactive Drugs
Tianna Magel, Lourdes Atziri Gonzalez Arreola, Daphne Guh, Scott MacDonald, Scott Harrison, Martin Schechter, Eugenia Oviedo-Joekes
Identifying typical doses of existing opioid use disorder medications, such as injectable opioid agonist treatment (iOAT), can support client and program needs, and potentially increase iOAT expansion. Longitudinal data from participants in a cohort study ( n  = 131), along with clinic dispensation records from August 2014 to April 2020, were used to examine physician prescribed as well as used doses of injectable diacetylmorphine and hydromorphone. Dosage groups, by medication and prescribed dose per session, were created for both hydromorphone and diacetylmorphine...
April 9, 2024: Journal of Psychoactive Drugs
Cassidy R LoParco, Sofia E Olsson, Kaylin M Greene, Carla J Berg, Scott T Walters, Zhengyang Zhou, Matthew E Rossheim
Driving under the influence (DUI) of alcohol or cannabis poses public health risks. Little is known about DUI of Delta-8 THC, a newer cannabis product. Using 2022 survey data among 189 U.S. adults ages 18-25 (58.73% male, 59.26% non-Hispanic White), multivariable logistic regression examined substance-specific (alcohol, cannabis, Delta-8) DUI perceived likelihood and risk in relation to past-year DUI among those with past-year use of each. Overall, 72.49% reported past-year alcohol use, 50.53% cannabis, and 22...
April 9, 2024: Journal of Psychoactive Drugs
Barbara K Campbell, Thao Le, Caravella McCuistian, Catherine Bonniot, Kevin Delucchi, Joseph Guydish
A California-sponsored, 18-month, tobacco-free intervention in residential substance use disorder (SUD) programs was associated with increases in tobacco-free grounds and tobacco-related client services. The current study examined whether positive results would be replicated in 11 programs participating subsequently. Program directors ( N  = 11) completed surveys of tobacco-related policies pre- and post-intervention. Pre- ( n  = 163) and post-intervention ( n  = 128) cross-sectional staff surveys examined tobacco-related training, beliefs, practices, smoking policy, and smoking status...
February 16, 2024: Journal of Psychoactive Drugs
Liu Liu, Zhenni Tang, Xuemeng Li, Wing Hong Chui
This study explores the intentions and experiences of individuals seeking abstinence from heroin use through voluntary rehabilitation, as well as challenges to achieving a positive outcome. This study used semi-structured interviews with 37 individuals (22 female) who used heroin and utilized rational choice theory to guide data analysis. This study found that participants tried both medical and non-medical treatment methods but faced structural and personal barriers that hindered their efforts. While ceasing heroin use would presumably benefit their health and family relationships, individuals perceived the physical, psychological, and social costs of abstinence as outweighing the potential benefits and ultimately resumed heroin use...
February 13, 2024: Journal of Psychoactive Drugs
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