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Journals Journal of Clinical Psychophar...

Journal of Clinical Psychopharmacology

https://read.qxmd.com/read/36825887/risk-of-major-malformations-following-first-trimester-exposure-to-olanzapine-preliminary-data-from-the-massachusetts-general-hospital-national-pregnancy-registry-for-psychiatric-medications
#1
JOURNAL ARTICLE
Adele C Viguera, Marlene P Freeman, Lauren A Kobylski, Ella T Rossa, Peter Gaccione, David Chitayat, Sonia Hernández-Díaz, Lee S Cohen
PURPOSE/BACKGROUND: Since its US Food and Drug Administration approval in 1996, olanzapine has been one of the most commonly prescribed atypical antipsychotics, making a better understanding of its reproductive safety profile critical. The goal of the current analysis was to determine the risk of major malformations among infants exposed to olanzapine during pregnancy compared with a group of nonexposed infants. METHODS/PROCEDURES: The National Pregnancy Registry for Psychiatric Medications is a prospective pharmacovigilance program in which pregnant women are enrolled and interviewed during pregnancy and the postpartum period...
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825870/cerebellar-cognitive-affective-syndrome-and-delusional-disorder-associated-with-long-term-phenytoin-use-a-case-report
#2
JOURNAL ARTICLE
Hulya Malali Metin, Taner Aksu, Utku Ogan Akyildiz, Levent Sevincok
No abstract text is available yet for this article.
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825867/serotonin-paradox-in-burning-mouth-syndrome-reply
#3
JOURNAL ARTICLE
Abhiram Narasimhan Purohith
No abstract text is available yet for this article.
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825866/pharmacological-treatment-of-disinhibition-in-acquired-brain-injury
#4
JOURNAL ARTICLE
Grace Song, Mira Koro, Leon Berzen, Anthony Tung, Andrew Ryan, Joseph Chun Wearn Tham
PURPOSE/BACKGROUND: Traumatic brain injury is a major universal public health concern and results in chronic neurobehavioral sequelae including disinhibition. Objectives of this study were to review the literature on pharmacological treatment of disinhibition post-acquired brain injury (ABI), describe a snapshot of pharmacotherapy used in ABI at a tertiary neuropsychiatric unit in British Columbia, Canada, and share expert opinion. METHODS/PROCEDURES: A retrospective chart review of 11 patients from October to December 2021 was conducted based on exclusion criteria: age greater than 18 years, primary neurodegenerative conditions, or aphasia...
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825865/feasibility-and-effect-of-increasing-clozapine-plasma-levels-in-long-stay-patients-with-treatment-resistant-schizophrenia
#5
JOURNAL ARTICLE
Jan P A M Bogers, Peter F J Schulte, Theo G Broekman, Lieuwe de Haan
BACKGROUND: It is unknown whether increasing the clozapine plasma level to 400, 750, or even 1000 ng/mL is a feasible and effective strategy in patients with treatment-resistant schizophrenia (TRS). We investigated this in long-stay patients with TRS. METHODS: In long-stay TRS patients, doses of clozapine were increased gradually to reach target plasma levels of 400, 750, or 1000 ng/mL, depending on the clinical response and tolerability. After an effective or tolerated level was reached, positive and negative syndrome scale scores were evaluated after 3 months and 1 year...
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825864/serotonin-paradox-in-burning-mouth-syndrome
#6
JOURNAL ARTICLE
Takahiko Nagamine
No abstract text is available yet for this article.
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36825857/impact-of-a-caffeine-restriction-policy-on-inpatients-with-schizophrenia-a-pre-post-comparison-using-electronic-health-records
#7
JOURNAL ARTICLE
Juliette Lagreula, Mattia Ferraiolo, Philippe De Timary, Benoit Delatte, Laure Elens, Emmanuel Hermans, Olivia Dalleur
BACKGROUND/PURPOSE: Caffeine is the most commonly used psychostimulant worldwide. Although its large intake is suspected to worsen psychotic symptoms because of increasing dopamine neurotransmission, schizophrenic patients are heavier caffeine consumers than the general population. This study aims to assess the impact of a caffeine restriction policy in a psychiatric hospital on patient psychopathology, hospitalization characteristics, and psychotropic prescribing patterns. METHODS: It is a retrospective cross-sectional study based on electronic health records of a psychiatric hospital in the French-speaking area of Belgium...
February 27, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36821484/misidentified-dopamine-agonists-undermine-investigation-into-aripiprazole-link-with-impulse-control-disorders
#8
JOURNAL ARTICLE
David M Gardner
No abstract text is available yet for this article.
February 24, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36821468/thoughts-on-the-value-of-case-series-in-the-literature-an-example-using-the-article-on-lurasidone-augmentation-of-clozapine-in-refractory-schizophrenia
#9
JOURNAL ARTICLE
Austin G Armstrong, Sheldon H Preskorn
No abstract text is available yet for this article.
February 24, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36821462/reply-misidentified-dopamine-agonists-undermine-investigation-into-aripiprazole-link-with-impulse-control-disorders
#10
JOURNAL ARTICLE
Mahyar Etminan, Mohit Sodhi, Bruce Carleton
No abstract text is available yet for this article.
February 24, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36821406/%C3%AE%C2%BA-opioid-receptor-plasma-levels-are-associated-with-sex-and-diagnosis-of-major-depressive-disorder-but-not-response-to-ketamine
#11
JOURNAL ARTICLE
Brandi Quintanilla, Gustavo C Medeiros, Dede Greenstein, Peixiong Yuan, Jenessa N Johnston, Lawrence T Park, Fernando S Goes, Todd D Gould, Carlos A Zarate
BACKGROUND: Preclinical evidence indicates that the κ-opioid receptor (KOR)/dynorphin pathway is implicated in depressive-like behaviors. Ketamine is believed to partly exert its antidepressant effects by modulating the opioid system. This post hoc study examined the following research questions: (1) at baseline, were there differences in KOR or dynorphin plasma levels between individuals with major depressive disorder (MDD) and healthy volunteers (HVs) or between men and women? (2) in individuals with MDD, did KOR or dynorphin baseline plasma levels moderate ketamine's therapeutic effects or adverse effects? and (3) in individuals with MDD, were KOR or dynorphin plasma levels affected after treatment with ketamine compared with placebo? METHODS: Thirty-nine unmedicated individuals with MDD (23 women) and 25 HVs (16 women) received intravenous ketamine (0...
February 24, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36795032/antidepressant-poisoning-trends-in-pediatric-intensive-care-a-comparative-study-of-new-and-old-generation-antidepressants
#12
JOURNAL ARTICLE
Anar Gurbanov, Hande Kandemir, Lala Gurbanova, Emrah Gün, Edin Botan, Burak Balaban, Fevzi Kahveci, Hasan Özen, Hacer Uçmak, İhsan Özdemir, Merve Havan, Deniz Tekin, Tanıl Kendirli
PURPOSE/BACKGROUND: This study aimed to compare the frequency, clinical findings, treatment practices, and outcomes of toxicity to old-generation (OG) and new-generation (NG) antidepressants in our pediatric intensive care unit (PICU) by year-to-year. METHODS/PROCEDURES: The study included patients hospitalized for antidepressant poisoning during the 11-year period of January 2010 through December 2020. Antidepressants were classified as OG and NG. The groups were compared in terms of patient demographic characteristics, type of poisoning (accidental/suicidal), clinical findings, supportive and extracorporeal treatments received, and outcomes...
February 16, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36795014/valproate-associated-hyperammonemic-encephalopathy-clinical-correlates-and-management-strategies-in-a-tertiary-care-center
#13
JOURNAL ARTICLE
Sivapriya Vaidyanathan, Shalaka Chatorikar, Samir Kumar Praharaj, Ravindra Neelakanthappa Munoli, Suma T Udupa
BACKGROUND: Common adverse effects of valproate include sedation, tremor, gastrointestinal effects, and weight gain. Valproate-associated hyperammonemic encephalopathy (VHE) is an uncommon adverse effect of valproate therapy, which includes symptoms such as tremors, ataxia, seizures, confusion, sedation and coma. We report clinical features and management of 10 cases of VHE in a tertiary care center. METHODS: In a retrospective chart review of case records from January 2018 to June 2021, 10 patients with VHE were identified and included in this case series...
February 16, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36735587/hodgkin-lymphoma-in-patients-receiving-clozapine-treatment-2-case-reports-and-literature-review
#14
JOURNAL ARTICLE
Melike Karaçam Doğan, Nilgün Oktar Erdoğan, Aygün Ertuğrul, Ayşe Elif Anil Yağcioğlu, M Kâzim Yazici
No abstract text is available yet for this article.
February 4, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36735578/clozapine-dose-sex-ethnicity-smoking-habit-age-body-weight-and-plasma-clozapine-and-n-desmethylclozapine-norclozapine-concentrations-in-clinical-practice
#15
JOURNAL ARTICLE
Robert James Flanagan, Samora Hunter, Stephen John Obee, Suzanne Reeves
BACKGROUND: Guidance on clozapine dosing in treatment refractory schizophrenia is based largely on data from young adult male White patients. AIM: This study aimed to audit the plasma clozapine and N-desmethylclozapine (norclozapine) concentrations attained in male and female patients of different ethnicity and smoking habit. METHOD: The effect of dose, sex, ethnicity, age, body weight, and smoking habit on plasma clozapine and norclozapine concentrations were studied using data from a therapeutic drug monitoring service, 1993 to 2017...
February 4, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36719407/ultra-treatment-resistant-schizophrenia-and-clozapine-augmentation
#16
JOURNAL ARTICLE
Srinivasan Tirupati
No abstract text is available yet for this article.
February 1, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36706305/treatment-of-clozapine-associated-sialorrhea-the-role-of-benzamide-derivatives
#17
JOURNAL ARTICLE
Chanoch Miodownik, Anatoly Kreinin, Paul P Lerner, Shmuel Sokolik, Vladimir Lerner
PURPOSE: Hypersalivation is one of the most prevalent and distressing adverse effects associated with clozapine treatment. Currently, there is no standard therapeutic approach toward how to overcome it. Clinicians use various medications for managing this adverse effect. However, some of the agents are not effective enough, whereas others can induce other adverse effects. Recently, several reviews have been published on the treatment of clozapine-associated hypersalivation, in which the focus was on drugs from various pharmacological groups, and little attention was paid to drugs from the group of substituted benzamides...
January 30, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36706284/does-bupropion-increase-anxiety-a-naturalistic-study-over-12-weeks
#18
JOURNAL ARTICLE
Zachary Poliacoff, Heather G Belanger, Mirène Winsberg
PURPOSE/BACKGROUND: There has long been a clinical belief that bupropion exacerbates anxiety. The purpose of the current retrospective study is to compare anxiety severity over time in those prescribed selective serotonin reuptake inhibitors (SSRIs) versus bupropion. METHODS/PROCEDURES: Archival data (N = 8457) from patients receiving psychiatric care from a national tele-mental health company were used. Propensity matching was used to create SSRI and bupropion groups using 17 covariates...
January 30, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36700727/monoamine-oxidase-inhibitors-for-trichotillomania-a-case-series
#19
JOURNAL ARTICLE
Jon E Grant, Samuel R Chamberlain
PURPOSE/BACKGROUND: Despite several decades of research, there are no US Food and Drug Administration-approved medications for trichotillomania or medications generally approved in other geographical jurisdictions. Monoamine oxidase inhibitors show efficacy in the treatment of depression and some possible promise for obsessive compulsive disorder. METHODS/PROCEDURES: We present new data from a case series collected in a specialty clinical practice over a 4-year period...
January 25, 2023: Journal of Clinical Psychopharmacology
https://read.qxmd.com/read/36857556/salute-to-our-reviewers
#20
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2023: Journal of Clinical Psychopharmacology
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