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Annals of Nutrition & Metabolism

Jace Schell, Nancy M Betts, Timothy J Lyons, Arpita Basu
BACKGROUND: Postprandial metabolic impairments in diabetes have been shown to play an important role in vascular complications. Dietary polyphenols and other bioactive compounds in berries have been shown to improve postprandial hyperglycemia and related metabolic impairments, but few clinical studies have been reported in diabetes. OBJECTIVE: To examine the effects of daily dietary raspberries on postprandial and 4-week fasting glucose, lipids and biomarkers of inflammation in obese adults with type 2 diabetes...
February 14, 2019: Annals of Nutrition & Metabolism
Lijun Wang, Chenghe Ding, Fangfang Zeng, Huilian Zhu
β-Carotene has been reported to alleviate hepatic steatosis (SS), inflammation, and fibrosis in vivo and vitro studies. However, the clinical relevance of serum β-carotene and β-carotene-to-retinol (SC/SR) ratio with histological severity in nonalcoholic fatty liver disease (NAFLD) patients is unknown. This case-control study enrolled 24 control subjects and 62 NAFLD patients. Liver biopsies were collected and histological characteristics were assessed. Information with regard to demographic, anthropometric and dietary intake was assessed by face-to-face interviews with questionnaire...
February 13, 2019: Annals of Nutrition & Metabolism
Monica C Serra, Daniel P Beavers, Rebecca M Henderson, Jessica L Kelleher, Jessica R Kiel, Kristen M Beavers
BACKGROUND: Whether improvements in cardiometabolic health following weight loss (WL) are associated with changes in regional body fat distribution (gluteal vs. -android) is not well documented. METHODS: Older (age: 70 ± 4 years; mean ± SD) adults with obesity were randomized to a 6-month WL program (WL; n = 47), accomplished using a hypocaloric, nutritionally complete, higher protein -(targeting ≥1.0 g/kg/day) meal plan, or a weight stability (WS; n = 49) program...
February 12, 2019: Annals of Nutrition & Metabolism
Gholamreza Namazi, Parastoo Asa, Nizal Sarrafzadegan, Morteza Pourfarzam
BACKGROUND: The increased generation of reactive oxygen species that occurs in the case of a metabolic syndrome (MetS) may be responsible for the increased oxidative injury to erythrocyte membranes in coronary artery disease (CAD). Therefore, we studied the effects of MetS on both indexes of oxidative damage and biochemical properties of erythrocyte membranes in CAD patients. METHODS: We analyzed the markers of oxidative stress, Na+/K+-ATPase activity, total cholesterol content of erythrocyte membranes (CEM), and fatty acid compositions of the erythrocyte membrane in 82 patients with stable CAD and 39 non-CAD subjects...
February 7, 2019: Annals of Nutrition & Metabolism
Shohei Akagawa, Shoji Tsuji, Chikushi Onuma, Yuko Akagawa, Tadashi Yamaguchi, Mitsuru Yamagishi, Sohsaku Yamanouchi, Takahisa Kimata, Shin-Ichiro Sekiya, Atsushi Ohashi, Masaki Hashiyada, Atsushi Akane, Kazunari Kaneko
BACKGROUND/AIMS: The mode of delivery (vaginal or cesarean section) and feeding type (breastfeeding or formula feeding) of neonates are considered the most influential factors in the development of gut microbiota. OBJECTIVES: This study investigated the effect of prebiotic-rich breast milk on overcoming gut microbiota dysbiosis. METHOD: Stool samples from 36 healthy Japanese neonates were obtained at 4 days and 1 month of age, and divided into 4 groups based on mode of delivery and feeding type...
February 4, 2019: Annals of Nutrition & Metabolism
Berthold Koletzko, K M Godfrey, Lucilla Poston, Hania Szajewska, Johannes B van Goudoever, Marita de Waard, Brigitte Brands, Rosalie M Grivell, Andrea R Deussen, Jodie M Dodd, Bernadeta Patro-Golab, Bartlomiej M Zalewski
BACKGROUND: A considerable body of evidence accumulated especially during the last decade, demonstrating that early nutrition and lifestyle have long-term effects on later health and disease ("developmental or metabolic programming"). METHODS: Researchers involved in the European Union funded international EarlyNutrition research project consolidated the scientific evidence base and existing recommendations to formulate consensus recommendations on nutrition and lifestyle before and during pregnancy, during infancy and early childhood that take long-term health impact into account...
January 23, 2019: Annals of Nutrition & Metabolism
Carolina Maldonado Galdeano, Silvia Inés Cazorla, José María Lemme Dumit, Eva Vélez, Gabriela Perdigón
BACKGROUND: The gastrointestinal tract is one of the most microbiologically active ecosystems that plays a crucial role in the working of the mucosal immune system (MIS). In this ecosystem, the consumed probiotics stimulate the immune system and induce a network of signals mediated by the whole bacteria or their cell wall structure. This review is aimed at describing the immunological mechanisms of probiotics and their beneficial effects on the host. SUMMARY: Once administered, oral probiotic bacteria interact with the intestinal epithelial cells (IECs) or immune cells associated with the lamina propria, through Toll-like receptors, and induce the production of different cytokines or chemokines...
January 23, 2019: Annals of Nutrition & Metabolism
Takaki Kamiya, Daiki Hira, Nobuo Hoshino, Mika Kurihara, Mayumi Nakagawa, Masaya Sasaki, Tomohiro Terada
BACKGROUND/AIMS: Patients undergoing hematopoietic stem cell transplantation (HSCT) often receive total parenteral nutrition (TPN) due to poor oral intake. In clinical practice, it is difficult to predict adequate nutritional management, especially the duration of parenteral nutrition (PN), because of inter-individual variability in the conditions and types of treatment regimens. This study investigated the relationship between patient factors and the duration of TPN and the duration of PN...
January 23, 2019: Annals of Nutrition & Metabolism
Ting Chen, Fengyun Wang, Zhenyu Chu, Ling Sun, Haitao Lv, Wanping Zhou, Jie Shen, Linqi Chen, Miao Hou
OBJECTIVES: Spexin (SPX) is a novel peptide that has recently emerged as an important regulatory adipokine of obesity and related metabolic disease. Little is known about its role in children. The aim of the current study was to determine the potential role of SPX in obese children and explore its relationships with obesity-related markers, insulin sensitivity and pancreatic β cell function. METHOD: We studied the levels of serum SPX in 40 obese and 32 normal weight pre-puberty children (mean age was 8...
January 23, 2019: Annals of Nutrition & Metabolism
Joyce A Nettleton, Norman Salem
No abstract text is available yet for this article.
January 7, 2019: Annals of Nutrition & Metabolism
Daniel Weghuber, Emma Boyland, Margherita Caroli, Eva Erhardt, Marie-Laure Frelut, Anders Forslund, Artur Mazur, Susanne Ring-Dimitriou, Εlpis A Vlachopapadopoulou, David Thivel
No abstract text is available yet for this article.
January 7, 2019: Annals of Nutrition & Metabolism
Carla Assaf-Balut, Nuria García de la Torre, Alejandra Duran, Manuel Fuentes, Elena Bordiú, Laura Del Valle, Cristina Familiar, Johanna Valerio, Inés Jiménez, Miguel A Herraiz, Nuria Izquierdo, María J Torrejon, Maria Ángeles Cuadrado, Isabel Ortega, Francisco J Illana, Isabelle Runkle, Paz de Miguel, Inmaculada Moraga, Carmen Montañez, Ana Barabash, Martín Cuesta, Miguel A Rubio, Alfonso L Calle-Pascual
AIMS: The aim of the study was to evaluate the effect of a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on a composite of adverse maternofoetal outcomes of women with normoglycemia during pregnancy. METHODS: This was a sub-analysis of the St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic women were analysed (697). They were randomized (at 8-12th gestational weeks) to: standard-care control group (337), where fat consumption was limited to 30% of total caloric intake; or intervention group (360), where a MedDiet, enhanced with EVOO and pistachios (40-42% fats of total caloric intake) was recommended...
December 14, 2018: Annals of Nutrition & Metabolism
Armin Zittermann, Jana B Ernst, Sylvana Prokop, Uwe Fuchs, Jens Dreier, Joachim Kuhn, Cornelius Knabbe, Jochen Börgermann, Heiner K Berthold, Stefan Pilz, Ioanna Gouni-Berthold, Jan F Gummert
BACKGROUND/AIMS: We aimed to investigate the effect of a moderately high vitamin D dose on lipid parameters and biochemical markers of vascular calcification (VC) in patients with established cardiovascular disease. METHODS: We included in this pre-specified secondary analysis of a randomized controlled trial 161 patients with advanced heart failure and 25-hydroxyvitamin D (25OHD) concentrations < 75 nmol/L (vitamin D group: n = 80; placebo group: n = 81), who received a daily vitamin D3 supplement of 4,000 IU for 3 years...
December 14, 2018: Annals of Nutrition & Metabolism
Tomoaki Yatabe, Moritoki Egi, Masahiko Sakaguchi, Takashi Ito, Nobuhiro Inagaki, Hiromi Kato, Jun Kaminohara, Amane Konishi, Michiko Takahashi, Hiroomi Tatsumi, Masaru Tobe, Ikue Nakashima, Naoki Nakamoto, Takeshi Nishimura, Masakazu Nitta, Masaji Nishimura
BACKGROUND: There is lack of evidence regarding nutritional management among intensive care unit (ICU) patients in a population with relatively low body mass index. Therefore, we conducted an observational study to assess the nutritional management in Japanese ICUs. Also, we investigated the impact of nutritional management and rehabilitation on physical outcome. METHODS: The study population comprised 389 consecutive patients who received mechanical ventilation for at least 24 h and those admitted to the ICU for > 72 h in 13 hospitals...
December 12, 2018: Annals of Nutrition & Metabolism
Yun Qiu, Su-Fan Wang, Chao Yu, Qian Chen, Rui Jiang, Lei Pei, Yuan-Ling Huang, Neng-Zhi Pang, Zhenfeng Zhang, Wenhua Ling, Lili Yang
BACKGROUND/AIMS: Some adipokines, such as adiponectin and leptin, have been reported to be involved in the pathogenesis of nonalcoholic fatty liver disease (NAFLD), while the association of adipsin and visfatin with NAFLD still remains unclear. This study aimed to examine the association of circulating adipsin, visfatin, and adiponectin with NAFLD in Chinese adults. METHODS: We recruited a total of 211 eligible subjects, including 100 NAFLD cases and 111 age and sex frequency-matched controls...
December 12, 2018: Annals of Nutrition & Metabolism
Qin Cao, Yan Xiong, Zibiao Zhong, Qifa Ye
BACKGROUND: Computed tomography (CT)-assessed sarcopenia indexes have been reported to predict postoperative morbidity and mortality; however conclusions drawn from different indexes and studies remain controversial. AIM: The purpose of this meta-analysis was to evaluate various CT-assessed sarcopenia indexes as predictors of risk for major complications in patients undergoing hepatopancreatobiliary surgery for malignancy. METHODS: Medline/PubMed, Web of Science, and Embase databases were systematically searched to identify relevant studies published before June 2018...
December 4, 2018: Annals of Nutrition & Metabolism
Miranda C E Lomer, Orla Cahill, Aristea Baschali, Prasanna Partha Sarathy, Magda Sarantidou, Gerassimos J Mantzaris, Daniel R Gaya, Konstantinos Katsanos, Dimitrios K Christodoulou, Konstantinos Gerasimidis
BACKGROUND: Overnutrition and undernutrition can affect patients with inflammatory bowel disease (IBD). Although all IBD outpatients should be screened for nutrition risk, screening is not routinely performed, potentially leading to reduced identification and treatment. This study aimed to estimate the prevalence of nutrition risk in adult IBD outpatients and the proportion of cases who discussed diet and/or nutrition during their routine clinical appointment. METHODS: Adults with IBD attending outpatient clinics at 4 hospitals in Greece and in UK were recruited...
November 28, 2018: Annals of Nutrition & Metabolism
Joanna J Samulak, Angelika K Sawicka, Dace Hartmane, Solveiga Grinberga, Osvalds Pugovics, Wieslawa Lysiak-Szydlowska, Robert A Olek
BACKGROUND: L-carnitine can be metabolized to trimethylamine N-oxide (TMAO), a molecule that promotes atherogenesis through its interaction with macrophages and lipid metabolism. OBJECTIVE: The aim of the present study was to assess whether L-carnitine supplementation may promote changes in selected serum biomarkers of atherosclerosis. METHODS: Before the start, in the mid-point and after completing the 24-weeks supplementation protocol, fasting blood samples were taken from the antecubital vein...
November 28, 2018: Annals of Nutrition & Metabolism
Visith Chavasit, Wantanee Kriengsinyos
No abstract text is available yet for this article.
November 21, 2018: Annals of Nutrition & Metabolism
(no author information available yet)
No abstract text is available yet for this article.
2019: Annals of Nutrition & Metabolism
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