journal
MENU ▼
Read by QxMD icon Read
search

Journal of Clinical Immunology

journal
https://read.qxmd.com/read/31102036/recurrent-salmonella-typhi-infection-and-autoimmunity-in-a-young-boy-with-complete-il-12-receptor-%C3%AE-1-deficiency
#1
LETTER
Ankur Kumar Jindal, Deepti Suri, Sandesh Guleria, Amit Rawat, Sumit Garg, Amanjit Bal, Jean-Laurent Casanova, Jacinta Bustamante, Surjit Singh
No abstract text is available yet for this article.
May 17, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31102035/fifteen-years-of-the-j-project
#2
LETTER
László Maródi
No abstract text is available yet for this article.
May 17, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31102034/successful-rituximab-treatment-for-lymphoma-secondary-immunodeficiency-causing-debilitating-sinusitis-underlying-primary-immunodeficiency-disease-and-alternative-treatments-to-improve-the-quality-of-life
#3
EDITORIAL
https://read.qxmd.com/read/31089938/factors-beyond-lack-of-antibody-govern-pulmonary-complications-in-primary-antibody-deficiency
#4
Tamar Weinberger, Ramsay Fuleihan, Charlotte Cunningham-Rundles, Paul J Maglione
PURPOSE: Pulmonary complications occur frequently in primary antibody deficiency (PAD). While the impact of antibody deficiency may appear implicit for certain respiratory infections, immunoglobulin replacement therapy does not completely ameliorate pulmonary complications in PAD. Thus, there may be antibody-independent factors influencing susceptibility to respiratory disease in PAD, but these remain incompletely defined. METHODS: We harnessed the multicenter US Immunodeficiency Network primary immunodeficiency registry to compare prevalence of asthma, bronchiectasis, interstitial lung disease (ILD), and respiratory infections between two forms of PAD: common variable immunodeficiency (CVID) and x-linked agammaglobulinemia (XLA)...
May 14, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31089937/ikzf1-loss-of-function-variant-causes-autoimmunity-and-severe-familial-antiphospholipid-syndrome
#5
LETTER
Yannick Dieudonné, Aurélien Guffroy, Olivier Vollmer, Raphael Carapito, Anne-Sophie Korganow
No abstract text is available yet for this article.
May 14, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31079270/a-unique-presentation-of-infantile-onset-colitis-and-eosinophilic-disease-without-recurrent-infections-resulting-from-a-novel-homozygous-carmil2-variant
#6
Alina Kurolap, Orly Eshach Adiv, Liza Konnikova, Lael Werner, Claudia Gonzaga-Jauregui, Maya Steinberg, Vanessa Mitsialis, Adi Mory, Moran Y Nunberg, Sarah Wall, Ron Shaoul, John D Overton, Alan R Shuldiner, Yaniv Zohar, Tamar Paperna, Scott B Snapper, Dror S Shouval, Hagit Baris Feldman
PURPOSE: This study aimed to characterize the clinical phenotype, genetic basis, and consequent immunological phenotype of a boy with severe infantile-onset colitis and eosinophilic gastrointestinal disease, and no evidence of recurrent or severe infections. METHODS: Trio whole-exome sequencing (WES) was utilized for pathogenic variant discovery. Western blot (WB) and immunohistochemical (IHC) staining were used for protein expression analyses. Immunological workup included in vitro T cell studies, flow cytometry, and CyTOF analysis...
May 11, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31077002/caps-and-nlrp3
#7
REVIEW
Laela M Booshehri, Hal M Hoffman
Cryopyrin-associated periodic syndrome (CAPS) is a rare inherited autoinflammatory disorder characterized by systemic, cutaneous, musculoskeletal, and central nervous system inflammation. Gain-of-function mutations in NLRP3 in CAPS patients lead to activation of the cryopyrin inflammasome, resulting in the inappropriate release of inflammatory cytokines including IL-1β and CAPS-related inflammatory symptoms. Several mechanisms have been identified that are important for the normal regulation of the cryopyrin inflammasome in order to prevent uncontrolled inflammation...
May 10, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31073845/defining-primary-selective-igm-deficiency
#8
LETTER
Sudhir Gupta, Ankmalika Gupta
No abstract text is available yet for this article.
May 9, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31044336/ficolin-3-deficiency-is-associated-with-disease-and-an-increased-risk-of-systemic-lupus-erythematosus
#9
Anne Troldborg, Rudi Steffensen, Marten Trendelenburg, Thomas Hauser, Kasper G Winther, Annette G Hansen, Kristian Stengaard-Pedersen, Anne Voss, Steffen Thiel
PURPOSE: Ficolin-3 deficiency is caused by a mutation (+1637delC) in the FCN3 gene. It is a rare condition and has been associated with both infection and autoimmune disease including systemic lupus erythematosus (SLE). Here we investigated if ficolin-3 deficiency is more frequent in patients than in controls and tried to identify a common phenotype among ficolin-3 deficient individuals. Since a significant part of patients identified with ficolin-3 deficiency was diagnosed with SLE, we explored whether the heterozygous state of the FCN3+1637delC variant represents a risk factor in the development of SLE...
May 1, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31041574/graft-versus-host-disease-following-hla-matched-sibling-donor-compared-with-matched-related-donor-for-hematopoietic-stem-cell-transplantation-for-the-treatment-of-severe-combined-immunodeficiency-disease
#10
Bandar Al-Saud, Alhanouf Al-Saleem, Bashayer Al Rasheed, Abdulaziz Al-Ghonaium, Ali Al-Ahmari, Hamoud Al-Mousa, Amal Al-Seraihy, Rand Arnaout, Abdullah Al-Jefri, Sahar Elshorbagi, Nazeema Elsayed, Hasan Al-Dhekri, Mouhab Ayas, Saleh Al-Muhsen
BACKGROUND: One of the limiting factors for successful hematopoietic stem cell transplantation (HSCT) is graft versus host disease (GVHD). The EBMT/ESID guidelines for HSCT in severe combined immunodeficiency (SCID) recommend no GVHD prophylaxis for a matched sibling donor (MSD). OBJECTIVE: To determine the risk of GVHD in MSD HSCT for SCID patients compared to matched related donor (MRD). METHODS: This retrospective cohort study compares MSD with MRD and the outcome of GVHD in all SCID patients who underwent HSCT between 1993 and 2013...
April 30, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31037583/novel-malt1-mutation-linked-to-immunodeficiency-immune-dysregulation-and-an-abnormal-t-cell-receptor-repertoire
#11
Shirly Frizinsky, Erez Rechavi, Ortal Barel, Rose H Najeeb, Shoshana Greenberger, Yu Nee Lee, Amos J Simon, Atar Lev, Chi A Ma, Guangping Sun, Sarah A Blackstone, Joshua D Milner, Raz Somech, Tali Stauber
MALT1 (mucosa-associated lymphoid tissue lymphoma-translocation gene 1) is an intracellular signaling protein that activates NFκB and is crucial for both the adaptive and innate immune responses. Only 6 patients with immune deficiencies secondary to inherited mutations in the MALT1 gene have been described. PURPOSE: To provide clinical and immunological insights from 2 patients diagnosed with MALT1 immunodeficiency syndrome due to a novel MALT1 mutation. METHODS: Two cousins with suspected combined immunodeficiency underwent immunological and genetic work-up, including lymphocyte phenotyping, lymphocyte activation by mitogen stimulation, and next-generation sequencing (NGS) of T cell receptor gamma chain (TRG) repertoire...
April 29, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31025232/genetic-deficiency-and-biochemical-inhibition-of-itk-affect-human-th17-treg-and-innate-lymphoid-cells
#12
Ahmet Eken, Murat Cansever, Ido Somekh, Yoko Mizoguchi, Natalia Zietara, Fatma Zehra Okus, Serife Erdem, Halit Canatan, Sefika Akyol, Alper Ozcan, Musa Karakukcu, Sebastian Hollizeck, Meino Rohlfs, Ekrem Unal, Christoph Klein, Turkan Patiroglu
PURPOSE: Interleukin-2-inducible T cell kinase (ITK) is an important mediator of T cell receptor signaling. Loss of function mutations in ITK results in hypogammaglobulinemia and CD4+ T cell loss in humans, and the patients often present with EBV-associated B cell lymphoproliferative syndrome. Itk-deficient mice show loss of T cell naivety, impaired cytolytic activity of CD8+ T cells, and defects in CD4+ T cell lineage choice decisions. In mice, Itk mutations were shown to affect Th17-Treg lineage choice in favor of the latter...
April 25, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31016643/successful-lung-transplantation-in-a-patient-with-chronic-granulomatous-disease
#13
LETTER
Maylene Xie, Janet Lee, Maria Crespo, Merritt L Fajt, Norihisa Shigemura, Joseph M Pilewski, Andrej A Petrov
No abstract text is available yet for this article.
April 23, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/31001706/a-novel-carmil2-mutation-resulting-in-combined-immunodeficiency-manifesting-with-dermatitis-fungal-and-viral-skin-infections-as-well-as-selective-antibody-deficiency
#14
LETTER
Faranaz Atschekzei, Roland Jacobs, Martin Wetzke, Georgios Sogkas, Claudia Schröder, Gerrit Ahrenstorf, Akshay Dhingra, Hagen Ott, Ulrich Baumann, Reinhold Ernst Schmidt
No abstract text is available yet for this article.
April 18, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30993493/granule-cell-neuronopathy-in-a-patient-with-common-variable-immunodeficiency
#15
LETTER
Andrew McLean-Tooke, Constantine Chris Phatouros, Glenys Chidlow, David W Smith, Peter Silbert
No abstract text is available yet for this article.
April 16, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30989467/rnaseq-supports-the-molecular-genetic-diagnosis-of-late-onset-ada-deficiency
#16
LETTER
Christopher M Watson, Claire Stockdale, Ian Berry, Laura A Crinnion, Ian M Carr, Andrew Cant, David T Bonthron, Sinisa Savic
No abstract text is available yet for this article.
April 16, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30982207/hemorrhagic-pneumonia-as-the-first-manifestation-of-anhidrotic-ectodermal-dysplasia-with-immunodeficiency
#17
LETTER
Yuko Ichimiya, Motoshi Sonoda, Masataka Ishimura, Shunsuke Kanno, Shouichi Ohga
No abstract text is available yet for this article.
April 13, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30955145/successful-treatment-of-sinusitis-with-topical-human-milk-in-a-lymphoma-patient-using-rituximab
#18
LETTER
Nise Yamaguchi, Patricia Palmeira, Magda Carneiro-Sampaio
No abstract text is available yet for this article.
April 6, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30953287/interleukin-36-receptor-antagonist-deficiency-ditra-with-a-novel-il36rn-homozygous-mutation-c-200g-t-p-cys67phe-in-a-young-colombian-woman
#19
LETTER
Andres F Zea-Vera, Felipe E Estupiñan-Lopez, Jaqueline Cifuentes-Burbano, Myriam J Vargas, Anilza Bonelo
No abstract text is available yet for this article.
April 5, 2019: Journal of Clinical Immunology
https://read.qxmd.com/read/30953286/interferon-%C3%AE-receptor-1-deficiency-corrected-by-umbilical-cord-blood-transplantation
#20
LETTER
Thomas F Michniacki, Kelly J Walkovich, David G Frame, Mark T Vander Lugt
No abstract text is available yet for this article.
April 5, 2019: Journal of Clinical Immunology
journal
journal
28117
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"