journal
https://read.qxmd.com/read/37864522/trends-in-clinical-features-and-severity-of-plasmodium-vivax-malaria-among-children-at-tertiary-care-center-in-north-india
#21
JOURNAL ARTICLE
Aditi Arya, Shyam Sundar Meena, Monika Matlani, Shewta Chaudhry, Vineeta Singh
BACKGROUND: Malaria is a significant cause of morbidity and mortality in adults and children. Plasmodium falciparum is the primary cause of severe malaria, but recently Plasmodium vivax is also recognized to cause severe malaria-associated morbidity and mortality. The study focuses on determining the mortality related to severity parameters in individuals under 12 years and their critical presentation in P.vivax malaria-infected children. METHODS: A prospective cross-sectional hospital-based study was conducted at Safdarjung Hospital, New Delhi, and ICMR-NIMR, New Delhi...
October 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37830545/covid-19-lockdown-effect-on-healthcare-utilization-and-in-hospital-mortality-in-children-under-5-years-in-cape-town-south-africa-a-cross-sectional-study
#22
JOURNAL ARTICLE
Noradin Elmi, Liezl Smit, Thandi Wessels, Moleen Zunza, Helena Rabie
BACKGROUND: COVID-19 pandemic measures resulted in the de-escalation of non-COVID-19 healthcare provision. METHODS: A retrospective cross-sectional study of routinely collected data was done to investigate the effect of COVID-19 policies on the healthcare utilization and mortality of children younger than 5 years in Eastern Cape Town, South Africa. We compared visits to primary and urgent care facilities, hospitalization, in-hospital deaths, and vaccine uptake from 1 January to 31 December 2020 to similar periods in 2018 and 2019...
October 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37805828/cerebrospinal-fluid-tumor-necrosis-factor-alpha-tnf-%C3%AE-levels-in-children-with-cerebral-malaria
#23
JOURNAL ARTICLE
Rajniti Prasad, Raghvendra Singh Patel, S P Mishra, Ankur Singh, Abhishek Abhinay, Tej Bali Singh
This prospective cross-sectional study evaluated the diagnostic and prognostic role of cerebrospinal fluid (CSF) tumor necrosis factor-alpha (TNF-α) in children with cerebral malaria (CM) and its role in the differentiation of CM from non-cerebral severe malaria. CSF TNF-α was measured using a human TNF-α enzyme-linked immunosorbent assay kit of 39 cases of CM and 19 cases of non-cerebral severe malaria. CSF TNF-α levels were significantly higher in CM (p < 0.001). Based on the receiver operating characteristics curve, a cutoff value of CSF TNF-α was 5...
October 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37794754/prevalence-of-sleep-disorders-in-children-with-congenital-zika-syndrome
#24
JOURNAL ARTICLE
Carolina Santos Souza Tavares, Raquel Souza Marques, Victor Santana Santos, Hudson P Santos, Monique Carla da Silva Reis, Paulo Ricardo Martins-Filho
Studies have reported that children with Congenital Zika Syndrome (CZS) experience changes in their sleep patterns, which can result in mood disturbances, behavioral issues and delays in growth and development. This systematic review synthesized the available evidence on the prevalence of sleep disorders in children with CZS. Eligible studies were those with an observational design that reported sleep disorders in children with CZS using validated questionnaires, polysomnography/electroencephalographic recording or parent/caregiver reports...
October 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37715501/clinical-profile-of-infants-with-late-onset-sepsis-admitted-in-a-north-east-indian-tertiary-care-center-insights-into-the-uncharted
#25
JOURNAL ARTICLE
Sugunan Niranjana, Chongtham Shyamsunder Singh, Khuraijam Ranjana Devi, O Okendrajit Singh, Chabungbam Smilie, Sareet Kumari Nandeibam
OBJECTIVES: To assess the clinical profile of infants with late onset sepsis admitted in a tertiary care hospital in North-East India. METHODS: Prospective observational study was carried out in Department of Paediatrics, Regional Institute of Medical Sciences hospital during a period of 2 years (September 2019-August 2021). RESULTS: A total of 109 patients were included in the study, of which 80 were community-acquired and 29 infants were hospital-acquired cases of late onset sepsis (LOS)...
September 7, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37705261/evaluation-and-monitoring-of-eye-findings-in-children-exposed-to-zika-virus-during-gestation-3-years-of-follow-up
#26
JOURNAL ARTICLE
Maria Luiza Bernardes Dos Santos, Luiz Cláudio Santos De Souza Lima, Andrea Araújo Zin, Maria Elisabeth Lopes Moreira, Zilton Farias Moreira De Vasconcelos, Luiza Maceira De Almeida Neves, Maurício Bastos Pereira, Renata Artimos De Oliveira Vianna, Luis Guillermo Coca Velarde, Solange Artimos De Oliveira, Lee Woodland Riley, Claudete Aparecida Araújo Cardoso
INTRODUCTION: Congenital Zika syndrome (CZS) is a recently described disease. Our main objective was to evaluate and monitor, over 3 years, the ophthalmoscopic findings in children exposed to zika virus (ZIKV) during gestation. METHODS: This prospective observational study was conducted in Rio de Janeiro, Brazil, between April 2016 and May 2019. We evaluated two groups with exanthema serving as a proxy for viremia: (i) children whose mothers had exanthema during pregnancy and (ii) children who had microcephaly without maternal exanthema during pregnancy...
September 7, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37697654/pediatric-sepsis-profile-in-a-tertiary-care-hospital-in-indonesia-a-4-year-retrospective-study
#27
JOURNAL ARTICLE
Antonius Hocky Pudjiadi, Nina Dwi Putri, Stephanie Wijaya, Fatima Safira Alatas
AIM: This study aimed to explore the factors contributing to mortality and its management among pediatric sepsis patients at a single center in Indonesia. METHOD: We conducted a retrospective study of children admitted due to sepsis from January 2015 to December 2019 in an Indonesian tertiary hospital. RESULTS: The mortality rate of pediatric sepsis in our study was 76.1% among 176 records with outcome identified. Mortality was significantly associated with septic shock at triage, number of organ failure, intensive care unit admission, inotropic use, septic shock and severe sepsis during hospitalization...
September 7, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37674390/tissue-expression-of-the-sars-cov-2-cell-receptor-gene-ace2-in-children
#28
JOURNAL ARTICLE
Jiyi Huang, Zhibin Guo, Junkai Duan, Yong Zou, Kuai Chen, Hui Huang, Sheng Zhang, Yunguo Zhou
Coronavirus disease 2019 (COVID-19) has become a significant global public health problem. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which causes the disease, utilizes angiotensin-converting enzyme II (ACE2) as a major functional receptor to enter host cells. No study has systematically assessed ACE2 expression in multiple tissues in children. This study investigated ACE2 expression and ACE2 protein's histological distribution in various organs in paediatric patients (the small intestine, thymus, heart and lungs)...
September 7, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37674389/global-perspective-from-high-income-countries-on-phototherapy-threshold-differences-at-24-h-in-36-and-38-week-newborn-infants
#29
JOURNAL ARTICLE
Shabih Manzar
No abstract text is available yet for this article.
September 7, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37672804/competencies-of-junior-medical-doctors-in-managing-seriously-ill-and-injured-children-time-to-rethink-our-current-training-approach
#30
JOURNAL ARTICLE
Louisa Erasmus, Andrew Redfern, Liezl Smit
BACKGROUND: The correct treatment of very ill and injured children is critical, yet little is known about the competencies of South African (SA) junior doctors in managing these children. METHODS: This survey documents SA junior doctors' reported resuscitation training opportunities, experience, skills and knowledge. RESULTS: A total of 118 doctors (interns, medical officers and registrars) from paediatric departments affiliated with 7 medical schools, participated...
August 24, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37648424/catch-up-vaccination-and-enhanced-immunization-against-hepatitis-b-hepatitis-a-measles-mumps-rubella-and-varicella-in-children-with-idiopathic-thrombocytopenic-purpura
#31
JOURNAL ARTICLE
Serçin Taşar, Medine Ayşin Taşar, Rukiye Ünsal Saç, Bülent Alioğlu
BACKGROUND: Limited data exist about the vaccination of children with idiopathic thrombocytopenic purpura (ITP) against vaccine preventable diseases. This study identified the vaccination status of children with ITP against hepatitis A, hepatitis B, measles, mumps, rubella and varicella, completed the immunization of children with inadequate immunization, re-evaluated post-vaccination antibody titers and identified probable vaccination-related complications. PATIENTS AND METHODS: All of 46 children had chronic ITP were included...
August 24, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37616069/disseminated-bacillus-calmette-gu%C3%A3-rin-infection-role-of-imaging-in-the-evaluation-of-complications
#32
JOURNAL ARTICLE
Ardeshir Rajabi, Gholamreza Pouladfar, Yasamin Dehghan, Zahra Jafarpour, Alireza Dehghan
BACKGROUND: The Bacillus Calmette-Guerin (BCG) vaccine is generally used to prevent tuberculosis, particularly meningeal and miliary types, in childhood. This vaccine can rarely cause complications of varying severity, ranging from localized disease to a severe diffuse type known as disseminated BCG infection. Imaging modalities play an important role in the evaluation of different complications of disseminated BCG infection. This study aimed to assess and describe the imaging findings of disseminated BCG infection in order to help clinicians diagnose this life-threatening infection more accurately...
August 24, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37616068/knowledge-and-experiences-of-healthcare-workers-in-managing-children-with-neurometabolic-disorders-in-a-developing-country-a-cross-sectional-study
#33
JOURNAL ARTICLE
Arushi Gahlot Saini, Bhanudeep Singanamalla, Pradeep Kumar Gunasekaran, Gunjan Didwal, Savita Verma Attri
OBJECTIVE: To evaluate the knowledge and experiences of healthcare workers in the management of neurometabolic disorders. METHODS: A cross-sectional study was carried out among the 132 participants of a continued medical education program conducted in the Department of Pediatrics at a tertiary-care teaching hospital. A questionnaire-based feedback form was circulated among the participants, and their responses were analyzed. RESULTS: Ninety-three responses were analyzed...
August 24, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37608506/occurrence-of-kawasaki-disease-and-neoplasms-in-temporal-proximity-single-center-experience-and-systematic-review-of-literature
#34
JOURNAL ARTICLE
Aaqib Zaffar Banday, Alisha Babbar, Pratap Kumar Patra, Ankur Kumar Jindal, Deepti Suri, Vignesh Pandiarajan, Amit Rawat, Anju Gupta, Surjit Singh
Various factors (e.g., infections) have been postulated to trigger Kawasaki disease (KD) in genetically predisposed individuals. Whether neoplasms can trigger KD is largely unknown due to paucity of data. Herein, we provide a detailed account of KD occurring in temporal proximity (within 6 months) to neoplasms ('neoplasm-KD'). Patients with 'neoplasm-KD' diagnosed/treated at our center from January 1994 to May 2021 were included. Additionally, we performed a systematic literature review (as per PRISMA 2020 guidelines) utilizing PubMed, Web of Science and Scopus databases to retrieve details of all patients with 'neoplasm-KD' reported till June 2021...
April 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37464453/cryptosporidium-infection-and-associated-risk-factors-among-children-from-rural-areas-in-peru-a-nested-case-control-study
#35
JOURNAL ARTICLE
Jose Luis Paredes, Rafaella Navarro, David Durand, Theresa Jean Ochoa
This study aimed to detect the frequency of Cryptosporidium infection and associated risk factors among children from rural areas in Peru. A case-control study was conducted, nested in a cohort in two rural communities that included children between 6 and 13 months who were followed for 6 months. Cases were children whose fecal samples tested positive for Cryptosporidium infection using an immunochromatography test. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to analyze risk factors associated with Cryptosporidium infection...
April 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37203231/skin-to-skin-contact-and-its-effect-on-mothers-postpartum-psychological-distress-and-their-full-term-neonate-in-egypt
#36
JOURNAL ARTICLE
Asmaa A El Sehmawy, Shaimaa Younes Abd Elaziz, Rania Mahfouz Abd Elwahed, Asmaa Abdelghany Elsheikh
DESIGN: A randomized controlled study was conducted on 400 mothers, who were divided into two groups: 200 mothers who applied skin-to-skin infant care (SSC) for at least 1 h daily for 12 weeks and 200 mothers who performed the usual mother-infant care. The mothers were recruited from the Obstetric Department of Al-Zahraa University Hospital in Cairo, Egypt. The enrolled mothers' infants were assessed for body weight. Sleep hours and frequency of breast milk feeding were evaluated by the mother during the day...
April 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37019086/effect-of-integrated-intervention-to-prevent-child-drowning-in-rural-areas-of-guangdong-china-a-cluster-randomized-controlled-trial
#37
JOURNAL ARTICLE
Ruilin Meng, Haofeng Xu, Mingqu Zhang, Pengpeng Ye, Zhishan Zhou, Xuhao Zhu, Xingru Li, Lifeng Lin
BACKGROUND: Drowning is the leading cause of death for children under the age of 15 years in Guangdong Province, China. This serious public health issue also exists in low- and middle-income countries (LMICs), which have few value-integrated intervention programs. The current study presents an integrated intervention project that aims to explore an effective pattern of prevention for child drowning in rural areas and feasibility to perform in other LMICs. METHODS: We conducted a cluster randomized controlled trial by comparing the incidence of non-fatal drowning among children in two groups in rural areas of southern China...
April 5, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/37004730/early-detection-of-glomerular-dysfunction-and-renal-tubulopathy-in-children-with-sickle-cell-disease-in-india
#38
JOURNAL ARTICLE
Sonia Karapurkar, Radha Ghildiyal, Nikita Shah, Rachna Keshwani, Sujata Sharma
BACKGROUND: Sickle cell disease causes microvascular occlusion in different vascular beds. In kidneys, it leads to occult glomerular dysfunction causing asymptomatic microalbuminuria, proximal tubulopathy causing hyposthenuria and increased free water loss and distal tubulopathy causing poor urine acidification. We studied the prevalence of various types of renal dysfunction, the ability of different tests to detect it at an early stage and the correlation of these parameters in children receiving hydroxyurea (HU)...
February 6, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/36913556/chest-radiograph-findings-in-children-with-covid-19-a-retrospective-analysis-from-a-tertiary-care-paediatric-hospital-in-south-india
#39
JOURNAL ARTICLE
Kanimozhi Vendhan, Mithra Kathirrajan, Gopinathan Kathirvelu, Balasubramanian S
OBJECTIVE: The primary aim of this study is to document the chest X-ray findings in children with COVID-19 pneumonia. The secondary aim is to correlate chest X-ray findings to patient outcome. METHODS: We performed a retrospective analysis of children (0-18 years) with SARS-CoV-2 admitted to our hospital from June 2020 to December 2021. The chest radiographs were assessed for: peribronchial cuffing, ground-glass opacities (GGOs), consolidation, pulmonary nodules and pleural effusion...
February 6, 2023: Journal of Tropical Pediatrics
https://read.qxmd.com/read/36897068/prevalence-of-childhood-obesity-in-brazil-a-systematic-review
#40
JOURNAL ARTICLE
Fabrício De Paula Santos, Eliane Aparecida Ferraz Silva, Caroline Lana Veloso Baêta, Felipe Sávio Campos, Helton Oliveira Campos
The present study aimed to analyze the prevalence of childhood obesity in Brazil and compare it between boys and girls. This systematic review was conducted and reported according to the guidelines outlined in the PRISMA statement. A systematic search of electronic databases, including PubMed, LILACS, and SciELO, was performed in November 2021. Studies that met the following criteria were included: (i) original quantitative studies regardless of their design; (ii) childhood obesity was clearly defined; (iii) prevalence of childhood obesity was reported or it was possible to extract from tables or figures in the text; and (iv) eligible population included children under 12 years of age...
February 6, 2023: Journal of Tropical Pediatrics
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