Neuro Endocrinology Letters

OBJECTIVES: Lung ultrasound reduces the number of chest X-rays after thoracic surgery and thus the radiation. COVID-19 pandemic has accelerated research in lung ultrasound artifacts detection using artificial intelligence. This study evaluates the accuracy of artificial intelligence in A-lines detection in thoracic surgery patients using a novel hybrid solution that combines convolutional neural networks and analytical approach and compares it with a radiology resident and radiology experts' results...

BACKGROUND: The swine Sertoli cells (SCs) are more vulnerable to the environmental insults than other species. We observed that zearalenone (ZEA), a prevalent food contaminant, caused SCs oxidative damage and inhibits their proliferation. Therefore, a naturally occurring antioxidant, i.e., the deer blood phospholipids (DBP) has been selected to test its potentially protective effects on SCs. METHODS: Collect fresh samples of swine testicles, isolated, cultured and identified primary swine SCs...

The purpose of supervision is to ensure that clients' needs are met and to monitor the effectiveness of therapeutic interventions and the therapeutic relationship. Cognitive behavioural therapy (CBT) supervision is the systematic cooperation of the supervisee with the supervisor, which aims at increasing the therapists' competencies when working with specific clients. The advantage of supervision is the possibility to shape and develop the therapist's practical skills through specific techniques. This paper aims to review currently available CBT supervision strategies that boost the development of therapists' skills and provide possible examples...

Gonadotropin-releasing hormone (GnRH) plays a crucial role in regulating the human endocrine system. Synthesized primarily in the hypothalamus, GnRH manages the balance of reproductive hormones. This review highlights GnRH's various functions, particularly its impact on fertility, sexual development, and overall reproductive health through the regulation of gonadal development and function. Beyond its direct role in reproductive processes, GnRH also influences neuroprotection, cognition, and mood regulation, as shown by its activity in different regions of the nervous system...

INTRODUCTION: The relationship between a poorly functioning thyroid gland and erectile dysfunction (hereinafter, "ED") has been demonstrated in many studies. If a man has thyroid problems, it can negatively affect his ability to achieve or maintain an erection. The thyroid gland produces hormones that affect metabolism and overall body function, including blood circulation. If the thyroid gland is not functioning properly, it can lead to blood circulation disorders, which can affect erectile function...

OBJECTIVES: To create a Czech version of the Labor Coping Scale (LCS) evaluation tool intended for midwives when caring for a woman with labor pain, to evaluate its psychometric properties and to find out the opinion on it in clinical practice. MATERIALS AND METHODS: Are use a combination of methods. By using repeated back translation, the Czech version of the LCS tool was created. It included an assessment of the tool's content validity index and a questionnaire survey determining the midwives' approach to labor pain (N = 419), supplemented by a focus group method (N = 16 midwives)...

OBJECTIVE: To compare the impact of a commercial "sleep lotion" versus a placebo control lotion on salivary melatonin and sleep quality. METHODS: The presence of melatonin in the lotion was confirmed and quantitated with High Performance Liquid Chromatography (HPLC). In this randomized, controlled, double-blind crossover trial, undergraduate student participants applied lotions on two separate nights and we quantitated melatonin in saliva samples with enzyme linked immunosorbent assays...

OBJECTIVE: The article presents the results of a research study on a patient after an ischemic cerebral stroke, as presented in a case study. The aim of the research was to determine the impact of combined therapy, utilizing long-term and intensive special pedagogical care, occupational therapy and psychology, on the development of the patient's motor and communication abilities. The contribution deals with the possibilities of development and support for individuals in childhood after experiencing the illness, with the potential correction of identified deficits from a multidisciplinary perspective...

When studying the literature on current public health policy challenges, a number of rankings can be found, created from data collected and processed by different methods and from different sources, ordering the challenges by their significance. Inevitably, in global studies, there are errors caused by averaging data across populations that differ significantly in population size and the causes of the decline in disability-adjusted life years (DALYs), potentially in combination with years of life lost (YLL) and years of life lived with disability (YLD), that may serve as indicators of the health status of a given population (Lopez 2005)...

BACKGROUND: Obesity has long been regarded as a risk factor for abnormal liver function, although the quantitative relationship between them is not clear. This study aimed to investigate the relationship between body mass index (BMI) and gamma-glutamyl transpeptidase (GGT) in different gender populations. METHODS: The cross-sectional study included 221,934 people aged over 18 years and under 90 years who underwent physical examinations at Yijishan Hospital in Wuhu City from 2011 to 2016...

This review discusses the topic of synthetic neuroactive steroids. A brief introduction to the mode of action of neuroactive steroids is followed by a short overview of the best-known synthetic neuroactive steroids used in clinical practice and the reasons for their withdrawal from the market. The paper examines various aspects of 6 specific synthetic neuroactive steroids which either have been approved for treatment or are currently in advanced phases of clinical trials, and lists their indications, current experience, and undesirable adverse effects...

OBJECTIVES: There is a complex, reciprocal link between epilepsy and the hypothalami pituitary-adrenal (HPA) axis. This study aimed to evaluate the role of the HPA axis in individuals with focal epilepsy, including those with right- or left-hemispheric lateralized epilepsy. MATERIAL AND METHODS: The study comprised 60 individuals with focal epilepsy, ages 18 to 85, with seizures coming from a single hemisphere, no destructive lesions on cranial magnetic resonance imaging, and 32 healthy persons...

INTRODUCTION: The parallel process is a psychosocial phenomenon where the relationship dynamics between the therapist and the client are repeated in the supervisory relationship between the therapist and the supervisor. The concept of the parallel process can be a useful tool for understanding and solving problems in therapy. However, it can induce supervision drift or block the supervision process. OBJECTIVE: This article aims to familiarize the reader with parallel processes in cognitive-behavioural therapy (CBT) and schema therapy supervision and discuss how to manage this phenomenon in supervision...

OBJECTIVES: Intracerebral hemorrhage (ICH) is a serious public health problem with high mortality and morbidity. The current study aims to investigate the effects of rosiglitazone on the microglial distribution and the expression of PPARγ and CD36 in the ICH rat model. METHODS NEW: Sprague-Dawley male rats (n=116) were randomly divided into four groups: control, ICH, rosiglitazone, and PPARγ antagonist (GW9662). Hematoxylin-eosin staining was used to observe the brain edema in the ICH rat model...

OBJECTIVES: Physical restraint in the prone position is still utilized in healthcare facilities to immobilize violent patients. It is associated with the sudden death of violent patients. The aim of this study is to objectify the impact of physical restraint in the prone position on spirometric and ventilatory parameters. DESIGN: A pilot simulation study. MATERIAL AND METHODS: Ten university students were included in the study. They underwent two types of physical restraint: in the prone position with "chest kneeling" and in the lateral position...

OBJECTIVES: This preliminary study aims to examine the effects of tomato juice, which can be easily consumed regularly, on the physical and psychological states of healthy adults in the Coronavirus era. DESIGN: Prospective observational study. MATERIALS AND METHODS: Ten healthy adults (mean age, 39.7±4.2 years) who consumed 180 mL of tomato juice twice daily for 4 weeks were enrolled. Measurements were taken before and after 4 weeks of consumption for the items below...

INTRODUCTION: Recurrent Cushing's disease (recurrent CD) is an uncommon and intricate clinical form of Cushing's syndrome. However, the connection between the pathological types of ACTH-secreting PitNETs and the clinical signs of recurrent CD remains uncertain. CASE DESCRIPTION: A 64-year-old woman, previously diagnosed with renal carcinoma, was admitted to our hospital due to recent weight gain. Previous endocrine tests indicated fluctuating hypercortisolemia and a recurrent pituitary tumor over the past six years...

BACKGROUND: Idiopathic spinal epidural lipomatosis (iSEL) is frequently associated with the utilization of steroids, endocrine disorders, obesity, and surgical interventions. Nevertheless, the pathogenesis of iSEL remains inadequately understood. The study aimed to investigate the contribution of inflammatory factors to idiopathic epidural lipomatosis. METHODS: Thirteen patients with iSEL (Grade III, iSEL group) and 12 patients with lumbar disc herniation (control group) who underwent unilateral biportal endoscopy from March 2020 to April 2023 were enrolled...

Schema therapy is an integrative approach to treat patients with personality disorders and other complex psychological problems. Group schema therapy has been developed to enhance the effectiveness and efficiency of schema therapy by providing a supportive and stimulating environment for change. This article introduces the River of Life Method, a novel technique for facilitating group schema therapy, based on the metaphor of a river of life. The method helps patients to identify and modify their maladaptive schemas and modes in a nurturing process in the group...

BACKGROUNDS: Dual-antiplatelet therapy (DAPT) with aspirin and clopidogrel for minor strokes or TIAs has been demonstrated in several RCTs. Whether drug selection for mono-antiplatelet therapy (MAPT) following DAPT may influence stroke recurrence has not been clarified, especially for patients with intracranial atherosclerosis stenosis (ICAS). The Thrombelastography Platelet Mapping (TEG-PM) assay claimed to be capable of monitoring platelet function secondary to antiplatelet therapy...