journal
https://read.qxmd.com/read/38710306/risk-factors-for-multidrug-resistant-and-extensively-drug-resistant-acinetobacter-baumannii-infection-of-patients-admitted-in-icu-a-systematic-review-and-meta-analysis
#41
REVIEW
Haiqing Diao, Guangyu Lu, Yang Zhang, Zhiyao Wang, Xiaoguang Liu, Qiang Ma, Hailong Yu, Yuping Li
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Acinetobacter baumannii infections pose challenges for clinical treatment and cause high mortality, particularly in intensive care units (ICUs). Identifying the risk factors for MDR and XDR infection is crucial, and existing findings remain controversial. We aim to systematically summarize and analyze the risk factors for MDR/XDR A. baumannii-infected patients admitted to ICUs. We searched PubMed, Embase, Web of Science, and the Cochrane Library for eligible original studies published in English before October 2023...
May 4, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38705477/residual-risk-of-pseudomonas-aeruginosa-waterborne-contamination-in-intensive-care-unit-despite-the-presence-of-filters-on-all-water-points-of-use
#42
JOURNAL ARTICLE
Guilhem Royer, Maxine Virieux-Petit, Fabien Aujoulat, Clément Hersent, Sophie Baranovsky, Florence Hammer-Dedet, Agnès Masnou, Hélène Marchandin, Philippe Corne, Estelle Jumas-Bilak, Sara Romano-Bertrand
OBJECTIVE: To assess the residual risk of waterborne contamination by Pseudomonas aeruginosa (PA) from water network colonized by a single genotype (Sequence Type (ST)299) despite the presence of antimicrobial filters in a medical intensive care unit (ICU). METHODS: During the first 19-month period after ICU opening, water network contamination was assessed monthly by collecting water upstream the filters. Downstream water was also sampled to assess filters efficiency...
May 3, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38705476/air-dispersal-of-multidrug-resistant-organisms-including-methicillin-resistant-staphylococcus-aureus-carbapenem-resistant-acinetobacter-baumannii-and-carbapenemase-producing-enterobacterales-in-general-wards-surveillance-culture-of-air-grilles
#43
JOURNAL ARTICLE
Shuk-Ching Wong, Jonathan Hon-Kwan Chen, Monica Oi-Tung Kwok, Crystal Yuen-Ki Siu, Lithia Lai-Ha Yuen, Christine Ho-Yan AuYeung, Chi-Kuen Li, Bella Hong-Yan Li, Betsy Wai-Ka Chan, Simon Yung-Chun So, Kelvin Hei-Yeung Chiu, Kwok-Yung Yuen, Vincent Chi-Chung Cheng
BACKGROUND: The environmental surveillance of air grilles in clinical areas has not been systematically analyzed. METHODS: Samples were collected from frequently-touched items (n=529), air supply (n=295) and exhaust (n=184) grilles in six medical and eleven surgical wards for the cultures of multidrug-resistant organisms (MDROs): methicillin-resistant Staphylococcus aureus (MRSA), carbapenem-resistant Acinetobacter baumannii (CRAB), and carbapenemase-producing Enterobacterales (CPE), and isolates were selected for whole-genome analysis (WGS)...
May 3, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38705475/a-clinical-study-of-antibacterial-medical-textiles-containing-polyhydroxyalkanoate-oligomers-for-reduction-of-hospital-acquired-infections
#44
JOURNAL ARTICLE
Lin Lin Ma, Ying-Ying Wei, Jun Li, Yang-Yang Sun, Shi Rui Liu, Kit Ming Ma, Polly Hang-Mei Leung, Xiaoming Tao
INTRODUCTION: The prevention and control of hospital-acquired infections remain a significant challenge worldwide, as textiles used in hospital wards are highly involved in transmission processes. Herein, we report a new antibacterial medical fabric used to prepare hospital pillowcases, bottom sheets, and quilt covers for controlling and reducing hospital-acquired infections. METHOD: The medical fabric was composed of blended yarns of staple polyester and degradable poly(3-hydroxybutyrate co-3-hydroxyvalerate)/polylactide fibres, which were then coated with polylactide oligomers, an environmentally friendly and safe antimicrobial agent with excellent thermal stability in high-temperature laundry...
May 3, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38705474/assessing-the-stability-and-sporicidal-efficacy-of-oxidising-disinfectants
#45
JOURNAL ARTICLE
L Brown, A Marshall, L Conway, J Otter, P Norville, J Clarke
The role of the healthcare environment in the transmission of clinical pathogens is well established. We investigated the chemical stability and sporicidal efficacy of oxidising disinfectant products in the presence of simulated clean and medical dirty conditions. Performance of chlorine-releasing agents (sodium dichloroisocyanurate, chlorine dioxide and hypochlorous acid) was concentration-dependent, with 1000 ppm chlorine showing reduced stability and efficacy in dirty conditions. In contrast peracetic acid product demonstrated stability and consistently achieved efficacy in dirty conditions...
May 3, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38705473/qualitative-research-methods-powerful-tools-for-understanding-practice-and-informing-change
#46
EDITORIAL
Jennifer Broom, Alex Broom
No abstract text is available yet for this article.
May 3, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38688391/which-antiseptic-to-use-for-a-caesarean-section-a-systematic-review-and-network-meta-analysis-of-randomised-controlled-trials
#47
REVIEW
Ludwig Serge Aho Glele, Emmanuel Simon, Camille Bouit, Maeva Serrand, Laurence Filipuzzi, Paul Sagot, Karine Astruc, Philippe Kadhel
BACKGROUND: Guidelines for preoperative skin antisepsis recommend using chlorhexidine in an alcohol-based solution. However, other antiseptics such as aqueous povidone iodine or alcohol-based solutions are still used. Randomised controlled trials (RCTs) in Caesarean section (CS) are rare and do not include all possible comparisons of antiseptics. AIM: To assess the efficacy (reduction of surgical site infections) of chlorhexidine at two different concentrations (0...
April 28, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38685413/development-and-evaluation-of-test-methods-for-the-detection-and-enumeration-of-opportunistic-waterborne-pathogens-from-the-hospital-environment
#48
JOURNAL ARTICLE
Teresa Inkster, Isabel Caldwell, Heather Aird, Caroline Willis, Sandra Lai, John Mallon
BACKGROUND: Many Gram -negative bacteria other than Pseudomonas aeruginosa have been implicated in waterborne outbreaks but standardised laboratory detection methods for these organisms have not been established. AIM: We aimed to establish laboratory testing methodologies for six waterborne pathogens; Acinetobacter spp, Burkholderia spp, Cupriavidus spp, Delftia acidovorans, Elizabethkingia spp and Stenotrophomonas maltophilia. METHODS: Water samples were spiked by UK Health Security Agency labs and sent to the Glasgow Royal Infirmary lab for analysis...
April 27, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38685412/the-requirement-to-move-towards-standardisation-of-wastewater-sampling
#49
LETTER
Phillip Norville, Jonathan A Otter
No abstract text is available yet for this article.
April 27, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38679391/human-resource-management-to-assist-infection-prevention-and-control-professionals-a-scoping-review
#50
REVIEW
Rojda Ülgüt, Ivonne Tomsic, Iris F Chaberny, Thomas von Lengerke
Infection prevention and control (IPC) professionals are key intermediaries between hospital managers and frontline staff. During the novel coronavirus disease pandemic, IPC professionals faced new challenges. Unfortunately, research on human resource management (HRM) to support IPC during and between pandemics is lacking. Therefore, this scoping review aimed to elucidate the existing knowledge on HRM measures in this context and thus contribute to the pandemic preparedness of healthcare facilities. It was conducted as part of the "PREparedness and PAndemic REsponse in Germany (PREPARED)"-project within the Network University Medicine (NUM)...
April 26, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38679390/ml-based-risk-assessment-tool-to-rule-out-empiric-use-of-esbl-targeted-therapy-in-endemic-areas
#51
JOURNAL ARTICLE
Hersh D Ravkin, Rachel M Ravkin, Eitan Rubin, Lior Nesher
BACKGROUND: Antimicrobial stewardship focuses on identifying patients who require ESBL-targeted therapy. Rule-in tools have been extensively researched in areas of low endemicity; however, such tools are inadequate for areas with high rates of ESBL, as almost all patients will be selected. AIM: To develop a machine learning-based rule-out tool suitable for areas with high levels of resistance. METHODS: We used gradient boosted decision trees to train and validate a risk prediction model on data from 17,913 (45% ESBL) patients with Escherichia coli and Klebsiella pneumoniae in urine cultures...
April 26, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38677481/the-prophylactic-use-of-negative-pressure-wound-therapy-after-cardiac-surgery-a-meta-analysis
#52
REVIEW
Alessandro Fiocco, Martina Dini, Giulia Lorenzoni, Dario Gregori, Andrea Colli, Laura Besola
BACKGROUND: Surgical site infections (SSi) pose a frequent complication in cardiac surgery patients and lead to increased patient discomfort and extended hospitalization. AIM: This meta-analysis evaluates the protective role of single-use-negative-pressure-wound-therapy (sNPWT) devices on closed surgical wounds after cardiac surgery, and explores their potential preventive application across all cardiac surgery patients. METHODS: A comprehensive literature search was conducted on PubMed and Elsevier, focusing on studies related to "negative pressure wound therapy" or "PICO negative pressure wound therapy" combined with "cardiac surgery" or "sternotomy," published between 2000 and 2022...
April 25, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38677480/impact-of-covid-19-on-healthcare-associated-infections-and-antimicrobial-use-in-italy-2022
#53
JOURNAL ARTICLE
Costanza Vicentini, Antonino Russotto, Roberta Bussolino, Marta Castagnotto, Claudia Gastaldo, Luca Bresciano, Stefano Bazzolo, Dario Gamba, Silvia Corcione, Francesco Giuseppe De Rosa, Fortunato D'Ancona, Carla Maria Zotti
INTRODUCTION: We aimed to assess the impact of COVID-19 on healthcare associated infection (HAI) transmission and antimicrobial use (AMU) prevalence during the later stages of the pandemic. METHODS: A point prevalence survey (PPS) was conducted among 325 acute-care hospitals of 19/21 regions of Italy, during November 2022. Non COVID-19 patients were matched to COVID-19 patients according to age, sex, and severity of underlying conditions. HAI and AMU prevalence were calculated as the percentage of patients with at least one HAI or prescribed at least one antimicrobial over all included patients, respectively...
April 25, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38670495/pilot-randomised-experimental-study-evaluating-isopropyl-alcohol-and-uvc-radiation-in-the-disinfection-of-healthcare-workers-smartphones
#54
JOURNAL ARTICLE
A Lontano, D Pascucci, F Pattavina, S Vincenti, F Boninti, R Grossi, I Incitti, M Bilotta, R Pastorino, G Vento, F Gigli, R Liperoti, F De Meo, M Antonelli, S Lochi, P Laurenti
Smartphones in medical settings pose infection risks due to harbouring pathogenic bacteria. This pilot study assesses the effectiveness duration of sanitisation methods, focusing on 70% isopropyl alcohol wipes and UVC boxes, aiming to obtain preliminary data on the reduction in Total Bacterial Load 3 hours post-sanitisation. A randomised monocentric trial with two intervention arms (wipes and UVC boxes) was designed. As participants, healthcare workers from three wards at Fondazione Policlinico Universitario "A...
April 24, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38670494/octenidine-exposure-was-not-associated-with-reduced-octenidine-susceptibility-of-meticillin-resistant-staphylococcus-aureus-mrsa-in-an-extended-care-facility-in-singapore
#55
JOURNAL ARTICLE
Ying Wei Tang, Pei Yun Hon, Joanna Tan, Bee Fong Poh, Brenda Ang, Angela Chow
OBJECTIVES: Antiseptics such as chlorhexidine gluconate (CHG) and octenidine dihydrochloride (OCT) are frequently used in hospitals to prevent and control meticillin-resistant Staphylococcus aureus (MRSA) transmission. With increasing prevalence of reduced CHG susceptibility of MRSA, concerns are raised about the possibility of reduced OCT susceptibility. Hence, we evaluated the prevalence of reduced CHG and OCT susceptibility over 3 years and assessed the association between exposure to OCT and MRSA reduced susceptibility to OCT...
April 24, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38663517/practices-to-prevent-non-ventilator-hospital-acquired-pneumonia-a-narrative-review
#56
REVIEW
Alana Livesey, Samuel Quarton, Harriet Pittaway, Aditya Adiga, Frances Grudzinska, Davinder Dosanjh, Dhruv Parekh
Nosocomial infection has significant consequences in healthcare, at the individual level driving increased morbidity and mortality, but also at the organisational level due to increased costs. Hospital acquired pneumonia(HAP) is the most common nosocomial infection and is associated with high excess mortality, frequent use of broad spectrum anti-microbials and increased length of stay. In this review we explore the preventative strategies that have been examined in non-ventilator acquired hospital associated pneumonia (NVHAP)...
April 23, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38649121/endoscope-sampling-and-culturing-methods
#57
JOURNAL ARTICLE
Lionel Pineau, Michelle Alfa, Caroline Radix
Contamination rates reported in the literature for patient-ready flexible endoscopes vary from 0.4% to 49%. Unfortunately, the comparison and interpretation of these results is almost impossible since several factors including sampling and culturing methods, target levels for contamination or definition of indicator microorganisms vary widely from one study to the other. The objective of this study was to compare the efficacy of six duodenoscope sampling and culturing methods by means of extraction efficacy comparison, while at the same time identifying key parameters that provide optimal microbial recovery...
April 20, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38649120/inhibition-of-bacterial-growth-on-sinks-of-a-paediatric-intensive-care-unit-using-a-222-nm-far-ultraviolet-irradiation-device-care222%C3%A2-%C3%AF
#58
LETTER
Shinsuke Mizuno, Masashi Kasai
No abstract text is available yet for this article.
April 20, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38649119/is-detergent-only-cleaning-paired-with-chlorine-disinfection-the-best-approach-for-cleaning
#59
JOURNAL ARTICLE
Martin A Kiernan, Mark Garvey, Philip Norville, Jonathon A Otter, David J Weber
No abstract text is available yet for this article.
April 20, 2024: Journal of Hospital Infection
https://read.qxmd.com/read/38621514/trends-in-viable-microbial-bioburden-on-surfaces-within-a-paediatric-bone-marrow-transplant-unit
#60
JOURNAL ARTICLE
Samuel Watkin, Elaine Cloutman-Green, Martin Kiernan, Lena Ciric
INTRODUCTION: Despite their role being historically overlooked, environmental surfaces have been shown to play a key role in the transmission of pathogens causative of healthcare-associated infections (HCAI). To guide infection prevention and control (IPC) interventions and inform clinical risk assessments, more needs to be known about microbial surface bioburden. AIMS: To identify the trends in culturable bacterial contamination across communal touch sites over time in a hospital setting...
April 13, 2024: Journal of Hospital Infection
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