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Journal of Hospital Infection | Page 2

H Sharma, M R Ong, D Ready, J Coelho, N Groves, V Chalker, S Warren
BACKGROUND: Whole genome sequencing (WGS) of Streptococcus pyogenes linked to invasive disease has been used to identify and investigate outbreaks. The clinical application of WGS in real-time for outbreak control is seldom employed. AIMS: A fatal case of bacteraemia at a national orthopaedic hospital prompted an outbreak investigation to identify carriers and halt transmission using real-time WGS. METHODS: Retrospective surveillance was conducted to identify patients with Streptococcus pyogenes infections in the last year...
July 5, 2019: Journal of Hospital Infection
Rebecca E Stockwell, Emma L Ballard, Peter O'Rourke, Luke D Knibbs, Lidia Morawska, Scott C Bell
Hospital-acquired infections (HAI) continue to persist in hospitals, despite the use of increasingly strict infection control precautions. Opportunistic airborne transmission of potentially pathogenic bioaerosols may be one possible reason for this persistence. Therefore, we aimed to systematically review the concentrations and compositions of indoor bioaerosols in different areas within hospitals and the effects of different ventilation systems. Electronic databases (Medline and Web of Science) were searched to identify articles of interest...
July 4, 2019: Journal of Hospital Infection
Farhana Parvin, Honghua Hu, Greg S Whiteley, Trevor Glasbey, Karen Vickery
Cleaning is fundamental to infection control. This report demonstrates that a Staphylococcus aureus biofilm is significantly harder to remove than dried planktonic bacteria. A single wipe removed >99.9% (>3Log10 ) of dried planktonic bacteria, whereas only 1.48Log10 of biofilm (96.66%) was removed by a standardised wiping process after 50 wipes.
July 4, 2019: Journal of Hospital Infection
Chuanxi Fu, Ruiheng Xu
No abstract text is available yet for this article.
July 4, 2019: Journal of Hospital Infection
Sapna Gohil, Bernadette Donaghy, Darren Tature, Julia Kowal, Sarah Lea, Florence Yl Lai, Simon Range, Julian W Tang
No abstract text is available yet for this article.
July 4, 2019: Journal of Hospital Infection
Rindala Saliba, Caroline Neulier, Delphine Seytre, Alain Fiacre, Frédéric Faibis, Pierre Leduc, Marlène Amara, Françoise Jauréguy, Etienne Carbonnelle, Jean-Ralph Zahar, Laurence Marty
BACKGROUND: Detection of faecal carriers of carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) has become a routine medical practice in many countries. In an outbreak setting, several public health organizations recommend threenweekly rectal screenings to rule-out acquisition in contact patients. This strategy, associated with bed closures and reduction of medical activity for a relatively long time, seems costly. AIM: The objective of this study was to test the positive and negative predictive values of RT-PCR(GeneXpert®) carried-out at Day-0, compared to conventional three weekly culture-based rectal screenings, in identifying, among contact patients, those who acquired CPE/VRE...
July 4, 2019: Journal of Hospital Infection
Samuel Yui, Monika Muzslay, Kush Karia, Bronwen Shuttleworth, Shanom Ali, Natalia Dudzinska, Peter Wilson
Splashing from handwash basins may be a source of bacteria in the healthcare environment. A novel splash-reducing basin was assessed for its ability to reduce droplet formation during simulated handwashing. The basin was compared to two conventional basins commonly used in healthcare. Basins were mounted in a test system and tap flushed for 30 seconds with and without handwashing. Droplets were visualised with fluorescent dye. With conventional basins, >1000 droplets were formed during 30 second flushes and found to spread further than 2m...
July 3, 2019: Journal of Hospital Infection
Anouk P Meijs, Ida Prantner, Tommi Kärki, José A Ferreira, Pete Kinross, Elisabeth Presterl, Pille Märtin, Outi Lyytikäinen, Sonja Hansen, Andrásné Szőnyi, Enrico Ricchizzi, Rolanda Valinteliėnė, Simeone Zerafa, Sabine de Greeff, Thale Cathrine Berg, Paulo André Fernandes, Mária Štefkovičová, Angel Asensio Vegas, Theresa Lamagni, Muhammad Sartaj, Jacqui Reilly, Wendy Harrison, Carl Suetens, Mayke Bg Koek
BACKGROUND: In 2011-2012, the European Centre for Disease Prevention and Control (ECDC) initiated the first European point prevalence survey (PPS) of healthcare-associated infections (HAIs) in addition to targeted surveillance of the incidence of specific types of HAIs such as surgical site infections (SSIs). AIM: To investigate whether national and multi-country SSI incidence can be estimated from ECDC PPS data. METHODS: We included 159 hospitals from 15 countries that participated in both ECDC surveillance modules, aligning surgical procedures in the incidence surveillance to corresponding specialties from the PPS...
June 29, 2019: Journal of Hospital Infection
Rodric Vian Francis, Tim C Boswell, Nikunj Mahida
No abstract text is available yet for this article.
June 28, 2019: Journal of Hospital Infection
Kentaro Iwata, Naomi Morishita, Yoshimi Sakai, Kazuhisa Doimoto, Masami Nishiwaki
No abstract text is available yet for this article.
June 25, 2019: Journal of Hospital Infection
Laura Espenhain, T C Berg, H Bentele, Karin Nygård, O Kacelnik
AIM: The aim of this study was, for the first time, to describe in detail the epidemiology and impact of norovirus outbreaks in healthcare institituions (HCIs) in Norway to identify areas which may improve outbreak response. METHODS: We carried out an analysis of all reported norovirus outbreaks in hospitals and long-term care facilities (LTCFs) from week 34, 2005 to week 33, 2018. We described seasonality, symptoms and number of cases among personnel and patients...
June 21, 2019: Journal of Hospital Infection
James Gray, Phil Orton
No abstract text is available yet for this article.
June 21, 2019: Journal of Hospital Infection
Fatima Sana, Wajid Hussain, Gohar Zaman, LuqmanSatti, UmerKhurshid, Muhammad Tahir Khadim
No abstract text is available yet for this article.
June 21, 2019: Journal of Hospital Infection
Maude Fortier, Pauline Pistre, Victor Ferreira, Mariam Pinsonneault, Jeannie Medeiros Charbonneau, Catherine Proulx, Audrey Buisson, Philippe Morency-Potvin, David Williamson, Anita Ang
BACKGROUD: Antimicrobial misuse leading to drug resistance is a growing concern for clinicians. Improving antimicrobial stewardship programmes through development of new tools could be part of the solution. AIM: To evaluate antimicrobial use in hospitalized patients after implementation of an antimicrobial checklist for ward-based clinical pharmacists. METHODS: A checklist based on quality indicators of optimal antimicrobial use was implemented to standardize hospital pharmacists' assessment of antimicrobial therapy...
June 21, 2019: Journal of Hospital Infection
Maria A Boyle, Aoife Kearney, Philip Carling, Hilary Humphreys
Microbial contamination of the near-patient environment is an acknowledged reservoir for nosocomial pathogens. The hospital bed and specifically bed rails have been shown to be frequently and heavily contaminated in observational and interventional studies. While the complexity of bedrail design has evolved over the years, the microbial contamination of these surfaces has been incompletely evaluated. In many published studies, key design variables are not described, compromising the extrapolation of results to other settings...
June 20, 2019: Journal of Hospital Infection
Ying P Tabak, Sanjay Merchant, Gang Ye, Latha Vankeepuram, Vikas Gupta, Stephen G Kurtz, Laura A Puzniak
BACKGROUND: Multidrug resistant (MDR) Pseudomonas aeruginosa can negatively affect patients and hospitals. AIM: To evaluate excess mortality and cost burden among patients hospitalized with suspected respiratory infections due to MDR P. aeruginosa versus patients with non-MDR P. aeruginosa in 78 United States (US) hospitals. METHODS: We analyzed electronically captured microbiological and outcomes data of patients hospitalized with nonduplicate P...
June 19, 2019: Journal of Hospital Infection
Patrick P Fehling, Justin J Hasenkamp, Steffen S Unkel, Ina I Thalmann, Sandra S Hornig, Lorenz L Trümper, Simone S Scheithauer
BACKGROUND: Hand hygiene compliance even before infection prone procedures (indication 2, "before aseptic tasks", according to WHO) remains disappointing. The aim of this study was to improve hand hygiene compliance by implementing gloved hand disinfection as a resource-neutral process optimization strategy. METHODS: We performed a three-phase intervention study on a stem cell transplant ward. After baseline evaluation of hand hygiene compliance (phase 1) gloved hand disinfection was allowed (phase 2) and restricted (phase 3) to evaluate and differentiate intervention-derived from learning and time effects...
June 18, 2019: Journal of Hospital Infection
Bryn Short, Jason Brown, Christopher Delaney, Leighann Sherry, Craig Williams, Gordon Ramage, Ryan Kean
Surfaces within healthcare play a key role in the transmission of drug-resistant pathogens. Candida auris is an emerging multi-drug resistant yeast which has the ability to survive for prolonged periods on environmental surfaces. Here we show that the ability to form cellular aggregates increases survival after 14 days, which coincides with the upregulation of biofilm-associated genes. Additionally, the aggregating strain demonstrated tolerance to clinical concentrations of sodium hypochlorite and remain viable 14 days' post treatment...
June 18, 2019: Journal of Hospital Infection
C O'Connor, T Bicanic, J Dave, T J Evans, P Moxey, U Adamu, D Shakespeare, M Cotter
No abstract text is available yet for this article.
June 17, 2019: Journal of Hospital Infection
Rachel Herbert, James Hatcher, Elita Jauneikaite, Myriam Gharbi, Stephanie d'Arc, Nelofar Obaray, Tony Rickards, Monica Rebec, Oliver Blandy, Russell Hope, Anthony Thomas, Kathleen Bamford, Annette Jepson, Shiranee Sriskandan
BACKGROUND: Certain Clostridium difficile ribotypes have been associated with complex disease phenotypes including recurrence and increased severity, especially the well-described hypervirulent ribotype RT027. In this study we set out to determine the pattern of ribotypes causing infection and association if any with severity. METHODS: All faecal samples submitted to a large diagnostic laboratory for C. difficile testing between 2011 and 2013 were subject to routine testing and cultured...
June 17, 2019: Journal of Hospital Infection
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