Journal of Hospital Infection

Patricia Müller, Chee Keong Tan, Ulrike Ißleib, Lars Paßvogel, Benjamin Eilts, Katrin Steinhauer
BACKGROUND: Since the first appearance of Candida auris in 2009, this yeast species has become a relevant pathogen in the clinical field. C. auris has been detected on various surfaces in health facilities, thus being a target for appropriate disinfection procedures. Preventive measures have to be implemented based on disinfectants with proven efficacy against C. auris. AIM: The chemical tolerance of C. auris was compared with the surrogate test organism Candida albicans as established in the European standards (EN)...
May 23, 2020: Journal of Hospital Infection
S Vergnano, A Bamford, S Bandi, F Chappel, A Demirjian, K Doerholt, M Emonts, L F Antolin, A Goenka, L Jones, J Herberg, L Hinds, O McGarrity, P Moriarty, S O'Riordan, M Patel, S Paulus, D Porter, K Stock, S Patel
A survey was conducted in UK regional children's hospitals with paediatric intensive care and paediatric infectious disease (PID) departments to describe the characteristics of paediatric antimicrobial stewardship (PAS) programmes. A structured questionnaire was sent to PAS coordinators. 'Audit and feedback' was implemented in 13 out of 17 centres. Microbiology-led services were more likely to implement antimicrobial restriction (75% vs 33% in PID-led services), to focus on broad-spectrum antibiotics, and to review patients with positive blood cultures...
May 23, 2020: Journal of Hospital Infection
Jean Cyr Yombi, Julien De Greef, Anne-Sophie Marsin, Anne Simon, Hector Rodriguez-Villalobos, Andrea Penaloza, Leila Belkhir
No abstract text is available yet for this article.
May 22, 2020: Journal of Hospital Infection
Jun Sakai, Norihito Tarumoto, Yuta Orihara, Rieko Kawamura, Masahiro Kodana, Nanako Matsuzaki, Ryo Matsumura, Kana Okane, Toru Kawamura, Shinichi Takeuchi, Kazuo Imai, Takashi Murakami, Shigefumi Maesaki, Maeda Takuya
With the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) associated with COVID-19, a high-speed and convenient detection technology should be at the forefront of medical care worldwide. In this study, we evaluated the usefulness of GeneSoC®, a compact, high-speed reciprocal flow RT-qPCR system, for the detection of SARS-CoV-2. Our results support the use of this system for the rapid identification of SARS-CoV-2. This approach can contribute to the strategic selection of initial management strategies for patients with COVID-19...
May 21, 2020: Journal of Hospital Infection
Kin On Kwok, Henry Ho Hin Chan, Ying Huang, David Shu Cheong Hui, Paul Anantharajah Tambyah, Wan In Wei, Patsy Yuen Kwan Chau, Samuel Yeung Shan Wong, Julian Wei Tze Tang
Super-spreading events in an outbreak can change the nature of an epidemic. Therefore, it is useful for public health teams to determine if an ongoing outbreak has any contribution from such events, which may be amenable to interventions. We estimated the basic reproductive number (R0 ) and the dispersion factor (k) from empirical data on clusters of epidemiologically-linked COVID-19 cases in Hong Kong, Japan and Singapore. This allowed us to infer the presence or absence of super-spreading events during the early phase of these outbreaks...
May 21, 2020: Journal of Hospital Infection
Vimercati Luigi, Dell'Erba Alessandro, Migliore Giovanni, De Maria Luigi, Caputi Antonio, Quarato Marco, Stefanizzi Pasquale, Cavone Domenica, Ferorelli Davide, Sponselli Stefania, Mansi Francesca, Tafuri Silvio
SARS-CoV-2-related SARIs (severe acute respiratory infections) have a major impact on public health; moreover, healthcare workers (HCWs) are exposed to a high biological risk. The aim of this study was to show the prevention procedures in place in the University Hospital of Bari (Apulia Region, Southern Italy) to reduce this risk to HCWs, consisting of the enhancement of preventive measures and the activation of a report system to collect HCWs' contacts. To date, 23 confirmed cases of infections (0.4% of all HCWs) have been reported in a 30-day observation period...
May 20, 2020: Journal of Hospital Infection
Stacey Rawlinson
No abstract text is available yet for this article.
May 20, 2020: Journal of Hospital Infection
Barry Cookson
No abstract text is available yet for this article.
May 20, 2020: Journal of Hospital Infection
Ralph A C van Wezel, Anne C T Vrancken, Marieke Ernest, Johan Laurensse, Josephus P C M van Doornmalen Gomez Hoyos
AIM: To develop a protocol to ensure the quality of respiratory protective devices for healthcare workers nursing and treating patients with possible or confirmed COVID-19 in the Catharina hospital. BACKGROUND: Due to the COVID-19 outbreak a shortage of respirators is occurring worldwide; more specifically, CE-certified FFP2 respirators. This has resulted in an increased supply to hospitals of alternative respirators of uncertain quality. Nevertheless, the quality of the respirators used by our healthcare workers must be ensured...
May 20, 2020: Journal of Hospital Infection
J Patel
No abstract text is available yet for this article.
May 20, 2020: Journal of Hospital Infection
S A Egan, S Corcoran, H McDermott, M Fitzpatrick, A Hoyne, O McCormack, A Cullen, G I Brennan, B O'Connell, D C Coleman
BACKGROUND: Linezolid is an antibiotic used to treat infections caused by multi-drug resistant Gram-positive bacteria. Linezolid resistance in enterococci has been reported with increasing frequency, with a recent rise in resistance encoded by optrA, poxtA or cfr. AIM: To investigate a hospital outbreak of linezolid- and vancomycin-resistant Enterococcus faecium (LVREfm) using whole-genome sequencing (WGS). METHODS: Thirty-nine VREfm from patient screening (19 isolates, 17 patients) and environmental sites (20 isolates) recovered in October 2019 were investigated...
May 18, 2020: Journal of Hospital Infection
Daniele Donà, Costanza Di Chiara, Mike Sharland
No abstract text is available yet for this article.
May 17, 2020: Journal of Hospital Infection
Vimercati L, Tafuri S, Chironna M, Loconsole D, Fucilli Fim, Migliore G, Gesualdo L
No abstract text is available yet for this article.
May 16, 2020: Journal of Hospital Infection
I Bloise, B Gómez-Arroyo, J García-Rodríguez
No abstract text is available yet for this article.
May 15, 2020: Journal of Hospital Infection
Sarah M Gerver, Miroslava Mihalkova, Julian F Bion, A Peter R Wilson, Dimple Chudasama, Alan P Johnson, Russell Hope
BACKGROUND/AIM: Bloodstream infections (BSI) in Intensive Care Unit (ICU) patients are associated with increased morbidity, mortality and economic costs. Many BSI are associated with central venous catheters (CVCs). We established the Infection in Critical Care Quality Improvement Programme (ICCQIP) to initiate surveillance of BSIs in English ICUs. METHODS: A web-based data capture system was launched 01/05/2016 to collect all positive blood cultures (PBCs), patient-days and CVC-days...
May 15, 2020: Journal of Hospital Infection
B J Laan, M C Vos, J M Maaskant, M I van Berge Henegouwen, S E Geerlings
BACKGROUND: We previously conducted a successful project, entitled the RICAT-study, to reduce inappropriate use of intravenous and urinary catheters in medical wards to prevent healthcare-associated infections. AIM: To compare surgical and medical wards, and determine risk factors for inappropriate catheter use. METHODS: We performed a cross-sectional study from October, 2017 to May, 2018 in surgical wards of two university hospitals in the Netherlands...
May 15, 2020: Journal of Hospital Infection
S-C Wong, C H-Y AuYeung, G K-M Lam, E Y-L Leung, V W-M Chan, K-Y Yuen, V C-C Cheng
No abstract text is available yet for this article.
May 15, 2020: Journal of Hospital Infection
J O Falkinham
BACKGROUND: Non-tuberculous mycobacteria (NTM) infections in cardiac surgery patients, caused by Mycobacterium chimaera or Mycobacterium abscessus, have been traced to NTM-aerosols produced by heater-cooler units of cardiopulmonary bypass equipment. AIM: To develop a protocol to disinfect the water reservoir(s) of heater-coolers to reduce NTM numbers and thereby prevent potential NTM aerosolization; and to devise an approach to disrupt surface biofilms of heater-coolers to reduce reinoculation of the heater-cooler reservoir(s) after disinfection...
May 15, 2020: Journal of Hospital Infection
M J Bruins, S V de Vries-van Rossum, R Huiskes-Roerink, J A Wallinga, M Waindrich, K Creemers, J Oskam, G J H M Ruijs, S B Debast, G H J Wagenvoort
INTRODUCTION: Aging and comorbidities such as diabetes and vascular problems contribute to the increasing occurrence of chronic wounds. Since the beginning of 2016, we saw a marked increase of Arcanobacterium haemolyticum (ARH) in cultures of chronic wounds. AIM: To report the outbreak investigation of ARH cultured from chronic wounds and describe the implemented infection prevention measures. METHODS: In total 50 ARH isolates were sent to a reference laboratory for molecular typing...
May 14, 2020: Journal of Hospital Infection
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