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Journals American Journal of Dermatopat...

American Journal of Dermatopathology

https://read.qxmd.com/read/38354376/rapidly-progressive-and-debilitating-epithelioid-hemangioendothelioma-an-atypical-presentation-of-a-rare-malignant-cutaneous-vascular-neoplasm
#21
JOURNAL ARTICLE
Siddhartha Dash, Biswanath Behera, Parvathy Viswan, Kunal Garg, Madhusmita Sethy, Pavithra Ayyanar
Epithelioid hemangioendothelioma (EHE) is a rare vascular malignant tumor that comprises less than 1% of all vascular tumors. Cutaneous involvement in EHE can occur either by spreading from underlying bone or rarely could be limited to the skin and mostly presents as solitary well-circumscribed mass to an ill-defined infiltrative lesion. We present a case of rapidly progressive and debilitating EHE presenting multiple vascular papules and nodules. Histopathology showed an ill-circumscribed nodular proliferation of epithelioid and spindled cells in the dermis that extended into the subcutaneous tissue...
February 7, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354375/unraveling-prame-expression-in-desmoplastic-melanocytic-neoplasms-illuminating-its-diagnostic-significance-in-distinguishing-desmoplastic-spitz-nevi
#22
JOURNAL ARTICLE
Jesús Machuca-Aguado, Cecilia Iborra García-Trevijano, Carmen Orrego-Pereira, Ana María Montaña-Ramírez, Juan José Ríos-Martín
No abstract text is available yet for this article.
February 7, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354374/onychomatricoma-versus-superficial-acral-fibromyxoma-nestin-immunohistochemistry-is-a-help-in-the-differential-diagnosis
#23
JOURNAL ARTICLE
Christophe Perrin
No abstract text is available yet for this article.
February 7, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354373/cutaneous-malignant-mixed-tumor-with-pulmonary-metastasis-a-case-report-and-literature-review
#24
JOURNAL ARTICLE
Hannah Haberecht, Burak Tekin, Krista Warren, Ruifeng Ray Guo
BACKGROUND: Cutaneous malignant mixed tumor (MMT) is a rare sweat gland-derived tumor characterized by admixed malignant epithelial cells and chondromyxoid stroma. Approximately 50 cases have been described in the literature. Metastasis, which may occur in more than one-third of cases, is most common in the lung. METHODS: We summarized the clinicopathologic features of a patient with cutaneous MMT metastatic to the lungs. A literature review of similar cases was completed using Web of Science, Scopus, and PubMed databases...
February 7, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38175704/homozygous-loss-of-cdkn2-in-primary-cutaneous-cd8-lymphoma-nos
#25
JOURNAL ARTICLE
Alistair Robson, Joaninha Costa Rosa, Kristina Semkova, Farrah Bakr, Jose Cabecadas
Primary cutaneous acral CD8(+) lymphoma (AL) has been accepted as primary cutaneous acral CD8-positive T-cell lymphoproliferative disorder in the revised WHO and updated WHO-EORTC lymphoma classifications. Commonly arising on the ears and comprising a clonal cytotoxic CD8+ T-cell infiltrate, almost all cases follow an indolent clinical course. A single aggressive case reported in the literature had a deletion at the CDKN2 locus at 9p21. We report an atypical CD8+ T-cell proliferation arising on the chest of an elderly man who had some similarities to AL but with a very high proliferation rate, absent p16 protein expression, and homozygous loss of the CDKN2 locus using FISH analysis...
January 4, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38170737/metastatic-undifferentiated-melanoma-mimicking-a-primary-bone-tumor-a-potential-diagnostic-pitfall
#26
JOURNAL ARTICLE
Abby Wills, Megan Dibbern, Henry F Frierson, Shyam S Raghavan
Undifferentiated melanoma (UM) is defined by the loss of classic morphologic and immunohistochemical melanocytic markers. Reports in the literature are rare and show that UM usually occurs as a metastasis in the setting of a known primary cutaneous melanoma. The most common mutations in UM include those involving BRAF, NRAS, and KIT, which are almost invariably present in the parent melanoma. In this study, we report a case of a primary sinonasal melanoma with metastatic UM presenting with osteoclast-like giant cells and resembling a primary bone tumor...
January 3, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38170727/mosaic-muir-torre-syndrome-keratoacanthoma-as-a-piece-of-the-puzzle
#27
JOURNAL ARTICLE
Amber O'Brien, Sarah Macfarlane, Matthew Sommerlad, Schaida Schirwani
Lynch syndrome is an inherited condition, which increases the risk of numerous visceral malignancies and cutaneous tumors such as keratoacanthomas and sebaceous tumors. It is typically identified by immunohistochemistry of tissue taken from tumors or through genetic testing with next-generation sequencing. Diagnosing Lynch syndrome becomes more complex when the individual is mosaic for the relevant pathogenic variant. There are very few cases of this reported in the medical literature. It is even more unusual for the diagnosis to be made based on testing of a keratoacanthoma lesion...
January 3, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488353/persistent-hyperpigmented-macules-on-the-scalp-and-face-a-clinicopathologic-challenge-challenge
#28
JOURNAL ARTICLE
Nakisa B Sadeghi, Carolyn M Ziemer, Sam B Wu, Jayson R Miedema, Rachel C Blasiak
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488352/progressive-hyperpigmentation-on-the-face-in-a-skin-of-color-woman-challenge
#29
JOURNAL ARTICLE
Marianne E Gosch, Amy J McMichael, Angela G Niehaus, Omar P Sangüeza
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488351/geometric-patch-of-alopecia-in-a-young-man-challenge
#30
JOURNAL ARTICLE
Neelam Chhajed, Anupama Bains, Meenakshi Rao
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488350/persistent-hyperpigmented-macules-on-the-scalp-and-face-answer
#31
JOURNAL ARTICLE
Nakisa B Sadeghi, Carolyn M Ziemer, Sam B Wu, Jayson R Miedema, Rachel C Blasiak
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488349/progressive-hyperpigmentation-on-the-face-in-a-skin-of-color-woman-answer
#32
JOURNAL ARTICLE
Marianne E Gosch, Amy J McMichael, Angela G Niehaus, Omar P Sangüeza
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488348/pressure-alopecia-answer
#33
JOURNAL ARTICLE
Neelam Chhajed, Anupama Bains, Meenakshi Rao
No abstract text is available yet for this article.
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38488347/androgen-receptor-immunohistochemistry-is-superior-to-prame-for-the-differentiation-of-sebaceous-carcinoma-from-primary-cutaneous-basaloid-mimics
#34
JOURNAL ARTICLE
Craig Wakefield, Eleanor Russell-Goldman
Cutaneous sebaceous neoplasia comprises a spectrum of disease ranging from benign adenomas to malignant carcinomas. The hallmark of these lesions is sebaceous differentiation. However, poorly-differentiated sebaceous carcinoma (SC), which lacks significant overt sebaceous differentiation, can show morphologic overlap with a variety of other basaloid cutaneous neoplasms. The accurate classification of SC is essential not only for diagnosis, but also because of the potential association with Muir-Torre syndrome...
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457671/febrile-ulceronecrotic-mucha-habermann-disease-associated-with-hemophagocytic-lymphohistiocytosis-a-case-report-and-review-of-the-literature
#35
JOURNAL ARTICLE
Caroline Chen, Lauren M Fahmy, Celine M Schreidah, Cynthia M Magro, Larisa J Geskin
Mucha-Habermann disease (MHD) is an inflammatory skin disease characterized by polymorphous eruptions of erythematous, necrotic macules that have been reported for similarities to cutaneous T-cell lymphoma. Febrile ulceronecrotic MHD (FUMHD) represents a severe variant of MHD, marked by ulcers, hemorrhagic bullae, and systemic symptoms. Herein, we report a case of a severely atypical lymphomatoid expression of FUMHD associated with hemophagocytic lymphohistiocytosis (HLH). A previously healthy 21-year-old woman was admitted to the hospital with a rapidly progressive necrotic papular rash...
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38457669/cellular-cutaneous-epithelioid-hemangioma-harboring-the-rare-gata6-foxo1-gene-fusion
#36
JOURNAL ARTICLE
Jonathan A Tepp, Narasimhan P Agaram, Jason C Chang, Konstantinos Linos
Epithelioid hemangioma (EH) is a benign vascular tumor displaying diverse histomorphologies. Among these, one EH subtype comprises cellular sheets of atypical epithelioid cells, posing potential challenges in distinguishing it from malignant vascular lesions. In this case report, we present a cutaneous cellular EH that carries the rare GATA6::FOXO1 gene fusion, a recent discovery. Our aim is to provide an updated insight into the evolving knowledge of EHs while delving into the histologic and molecular characteristics of the primary differential diagnoses...
April 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354390/hyperkeratotic-pigmented-plaques-with-blaschkoid-distribution-in-a-child-challenge
#37
JOURNAL ARTICLE
Chrislene Olukoga, Azadeh Samiei, Gregory Borschel, Rachel Kowal
No abstract text is available yet for this article.
March 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354389/persistent-papules-in-erythema-elevatum-diutinum-treated-with-dapsone-challenge
#38
JOURNAL ARTICLE
Diana Olvera, M Yadira Hurley, Madelyn Jeter, Peter Chow, Wesley T Hodges
No abstract text is available yet for this article.
March 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354388/a-dermatomal-rash-challenge
#39
JOURNAL ARTICLE
Matthew Chung Yi Koh, Paul Anantharajah Tambyah, MeiQi May Liau, Soon Boon Justin Wong, Kong-Bing Tan
No abstract text is available yet for this article.
March 1, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38354387/expanding-the-spectrum-of-skin-neoplasms-in-muir-torre-syndrome-beyond-sebaceous-tumours
#40
JOURNAL ARTICLE
Pablo Díaz-Calvillo, Carmen Gómez-Jiménez, Doriane Sabushimike, Rogelio González-Sarmiento, Mónica Roncero-Riesco, Ángel Santos-Briz
No abstract text is available yet for this article.
March 1, 2024: American Journal of Dermatopathology
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